Role of CX3CL1/CX3CR1 Signaling Axis Activity in Osteoporosis.

abstract：:To evaluate the impact of low levels of high density lipoprotein cholesterol (HDL-c) on patients with LDL-c average levels, focusing on oxidative, lipidic, and inflammatory profiles. Patients with cardiovascular risk factors (n = 169) and control subjects (n = 73) were divided into 2 subgroups, one of normal HDL-c and...

journal_title：Mediators of inflammation

authors： Mascarenhas-Melo F,Sereno J,Teixeira-Lemos E,Marado D,Palavra F,Pinto R,Rocha-Pereira P,Teixeira F,Reis F

更新日期：2013-01-01 00:00:00

abstract：:The human virome comprises viruses that infect host cells, virus-derived elements in our chromosomes, and viruses that infect other organisms, including bacteriophages and plant viruses. The development of high-throughput sequencing techniques has shown that the human gut microbiome is a complex community in which the...

journal_title：Mediators of inflammation

authors： Focà A,Liberto MC,Quirino A,Marascio N,Zicca E,Pavia G

更新日期：2015-01-01 00:00:00

abstract：:Leptin participates in the inflammatory responses in multiple cell types and animal models. Chronic cerebral hypoperfusion (CCH) induces inflammation in the central nervous system (CNS), which acts as one of the main reasons for CCH-induced white matter lesions (WMLs). But whether leptin participates in the pathogenes...

journal_title：Mediators of inflammation

authors： Du Y,Song Y,Zhang X,Luo Y,Zou W,Zhang J,Fu J

更新日期：2020-12-18 00:00:00

abstract：:There is some anecdotal evidence that oxygen-ozone therapy may be beneficial in some human diseases. However so far only a few biochemical and pharmacodynamic mechanisms have been elucidated. On the basis of preliminary data we postulated that controlled ozone administration would promote an oxidative preconditioning ...

journal_title：Mediators of inflammation

authors： León OS,Menéndez S,Merino N,Castillo R,Sam S,Pérez L,Cruz E,Bocci V

更新日期：1998-01-01 00:00:00

abstract：:Both alveolar macrophages (AMs) and alveolar epithelial cells (AECs) are main targets of Mycobacterium tuberculosis (M. tuberculosis (Mtb)). Intercellular communications between mucosal AECs and AMs have important implications in cellular responses to exogenous insults. However, molecular mechanisms underpinning inter...

journal_title：Mediators of inflammation

authors： Yang Y,Sun Y,Xu J,Bao K,Luo M,Liu X,Wang Y

更新日期：2018-09-26 00:00:00

abstract：:Monocyte and macrophage diversity is evidenced by the modulation of cell surface markers and differential production of soluble mediators. These immune cells play key roles in controlling tissue homeostasis, infections, and excessive inflammation. Macrophages remove dead cells in a process named efferocytosis, contrib...

journal_title：Mediators of inflammation

authors： Stunault MI,Bories G,Guinamard RR,Ivanov S

更新日期：2018-12-10 00:00:00

abstract：:Concentrations of acute phase proteins (CRP: C-reactive protein, albumin) change during surgery. We investigated the acute phase response to circumcision and the effects of anaesthesia on this response. The children were divided into four groups; group 1 (intratracheal general anaesthesia, n=40), group 2 (general anae...

journal_title：Mediators of inflammation

authors： Buyukkocak U,Caglayan F,Caglayan O,Basar M,Cakmak M,Batislam E,Ulusoy S

更新日期：2005-10-24 00:00:00

abstract：:Invertebrates do not display the level of sophistication in immune reactivity characteristic of mammals and other 'higher' vertebrates. Their great number and diversity of forms, however, reflect their evolutionary success and hence they must have effective mechanisms of defence to deal with parasites and pathogens an...

journal_title：Mediators of inflammation

authors： Rowley AF

更新日期：1996-01-01 00:00:00

abstract：:Vascular complications of diabetes mellitus represent a major public health problem. Although many steps forward have been made to define the causes and to find the best possible therapies, the problem remains crucial. In recent years, more and more evidences have defined a link between microbiota and the initiation, ...

journal_title：Mediators of inflammation

authors： Biscetti F,Nardella E,Cecchini AL,Landolfi R,Flex A

更新日期：2019-05-08 00:00:00

abstract：:B-1a cells are distinguishable from conventional B cells, which are designated B-2 cells, on the basis of their developmental origin, surface marker expression, and functions. In addition to the unique expression of the CD5 antigen, B-1a cells are characterized by the expression level of CD23. Although B-1a cells are ...

journal_title：Mediators of inflammation

authors： Yamamoto W,Toyoda H,Xu DQ,Hanaki R,Morimoto M,Nakato D,Ito T,Iwamoto S,Bonno M,Tanaka S,Hirayama M

更新日期：2018-12-23 00:00:00

abstract：:Little is known about the cause and pathophysiology of middermal elastolysis (MDE). In this condition, variable inflammatory infiltrate may be present or not together with loss of elastic fibres in the middermis that spares both papillary and lower reticular dermis. MDE may be a consequence of abnormal extracellular m...

journal_title：Mediators of inflammation

authors： De Cunto G,Lamberti A,de Santi MM,Miracco C,Fimiani M,Lungarella G,Cavarra E

更新日期：2017-01-01 00:00:00

abstract：:Autism is a neurodevelopmental disorder characterized by problems in communication, social skills, and repetitive behavior. Recent studies suggest that apoptotic and inflammatory mechanisms may contribute to the pathogenesis of this disorder. Nuclear factor-κB (NF-κB) is an important gene transcriptional factor involv...

journal_title：Mediators of inflammation

authors： Malik M,Tauqeer Z,Sheikh AM,Wen G,Nagori A,Yang K,Brown WT,Li X

更新日期：2011-01-01 00:00:00

abstract：:Diabetic retinopathy is considered a neurovascular disorder, hyperglycemia being considered the main risk factor for this pathology. Diabetic retinopathy also presents features of a low-grade chronic inflammatory disease, including increased levels of cytokines in the retina, such as interleukin-1 beta (IL-1β). Howeve...

journal_title：Mediators of inflammation

authors： Baptista FI,Aveleira CA,Castilho ÁF,Ambrósio AF

更新日期：2017-01-01 00:00:00

abstract：:We have previously shown that immunodominant MBP peptides encapsulated in mannosylated liposomes (Xemys) effectively suppressed experimental allergic encephalomyelitis (EAE). Within the frames of the successfully completed phase I clinical trial, we investigated changes in the serum cytokine profile after Xemys admini...

journal_title：Mediators of inflammation

authors： Lomakin Y,Belogurov A Jr,Glagoleva I,Stepanov A,Zakharov K,Okunola J,Smirnov I,Genkin D,Gabibov A

更新日期：2016-01-01 00:00:00

abstract：:Fluid of artificial blisters from erythromelalgic skin areas in primary thrombocythaemia contained a high amount of prostaglandin-E-like activity. Dazoxiben did not alleviate the erythromelalgia in patients with primary thrombocythaemia despite complete inhibition of platelet malondialdehyde and thromboxane B(2) synth...

journal_title：Mediators of inflammation

authors： Michiels JJ,Zijlstra FJ

更新日期：1993-01-01 00:00:00

abstract：:Gout is a common inflammatory disease characterized by acute arthritis and hyperuricemia. A number of epidemiological studies have suggested the critical role of gout in carcinogenesis. The aim of this study was to estimate the association between gout and cancer risk by meta-analysis of all relevant studies published...

journal_title：Mediators of inflammation

authors： Wang W,Xu D,Wang B,Yan S,Wang X,Yin Y,Wang X,Sun B,Sun X

更新日期：2015-01-01 00:00:00

abstract：Objective:To profile maternal plasma metabolome in spontaneous preterm birth. Method:In this retrospective case-control study, we have examined plasma of patient with preterm birth (between 22 and 36 weeks of pregnancy (n = 57)), with threatened preterm labor (between 23 and 36 weeks of pregnancy (n = 49)), and with t...

journal_title：Mediators of inflammation

authors： Lizewska B,Teul J,Kuc P,Lemancewicz A,Charkiewicz K,Goscik J,Kacerovsky M,Menon R,Miltyk W,Laudanski P

更新日期：2018-02-15 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/3214105.]. ...

journal_title：Mediators of inflammation

authors： Liang Y,Chen Q,Du W,Chen C,Li F,Yang J,Peng J,Kang D,Lin B,Chai X,Zhou K,Zeng J

更新日期：2017-01-01 00:00:00

abstract：:The present study investigated the association between the rs12979860 polymorphism in the IL-28B gene and HTLV-1 infection as well as the development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HTLV-1-infected patients (26 HAM/TSP symptomatic and 53 asymptomatic) and 300 seronegative health...

journal_title：Mediators of inflammation

authors： Vallinoto AC,Santana BB,Sá KS,Ferreira TC,Sousa RC,Azevedo VN,Feitosa RN,Machado LF,Ishak MO,Ishak R

更新日期：2015-01-01 00:00:00

abstract：:Inflammation represents the immune system response to external or internal aggressors such as injury or infection in certain tissues. The body's response to cancer has many parallels with inflammation and repair; the inflammatory cells and cytokines present in tumours are more likely to contribute to tumour growth, pr...

journal_title：Mediators of inflammation

authors： Albulescu R,Codrici E,Popescu ID,Mihai S,Necula LG,Petrescu D,Teodoru M,Tanase CP

更新日期：2013-01-01 00:00:00

abstract：STUDY OBJECTIVES:To assess serum amyloid alpha (SAA) pleural fluid levels in parapneumonic effusion (PPE) and to investigate SAA diagnostic performance in PPE diagnosis and outcome. METHODS:We studied prospectively 57 consecutive patients with PPE (empyema (EMP), complicated (CPE), and uncomplicated parapneumonic effu...

journal_title：Mediators of inflammation

authors： Boultadakis V,Skouras V,Makris D,Damianaki A,Nikoulis DJ,Kiropoulos T,Oikonomidi S,Tsilioni I,Gourgoulianis K

更新日期：2011-01-01 00:00:00

abstract：:Specific binding sites for the anti-inflammatory protein annexin I have been detected on the surface of human monocytes and polymorphonuclear leukocytes (PMN). These binding sites are proteinaceous in nature and are sensitive to cleavage by the proteolytic enzymes trypsin, collagenase, elastase and cathepsin G. When m...

journal_title：Mediators of inflammation

authors： Euzger HS,Flower RJ,Goulding NJ,Perretti M

更新日期：1999-01-01 00:00:00

abstract：:Recent investigations have indicated that reactive metabolites and AGE-RAGE-mediated inflammation might play an important role in the pathogenesis of ischemia-reperfusion injury in liver transplantation. In this observational clinical study, 150 patients were enrolled following liver transplantation from deceased dono...

journal_title：Mediators of inflammation

authors： Brenner T,Fleming TH,Spranz D,Schemmer P,Bruckner T,Uhle F,Martin EO,Weigand MA,Hofer S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Exhaled nitric oxide (FeNO) has been reported to be elevated in the oxidative stress involved in asthmatic patients, and the reaction of nitric oxide (NO) with superoxide anions results in the formation of nitrotyrosine. The purpose of this study was to investigate the effect of inhaled steroid treatment on ...

journal_title：Mediators of inflammation

authors： Bodini A,Peroni DG,Zardini F,Corradi M,Alinovi R,Boner AL,Piacentini GL

更新日期：2006-01-01 00:00:00

abstract：Objective:To analyze the potential role of colchicine monotherapy in patients with tumor necrosis factor receptor associated periodic syndrome (TRAPS) in terms of control of clinical and laboratory manifestations. Methods:Patients with TRAPS treated with colchicine monotherapy were retrospectively enrolled; demographi...

journal_title：Mediators of inflammation

authors： Vitale A,Sota J,Obici L,Ricco N,Maggio MC,Cattalini M,Ruscitti P,Caso F,Manna R,Viapiana O,Caggiano V,Emmi G,Insalaco A,Montin D,Licciardi F,Soriano A,Dagna L,Salvarani C,Lamacchia V,Hernández-Rodríguez J,Giacomel

更新日期：2020-05-27 00:00:00

abstract：:Rheumatoid arthritis (RA), a chronic inflammatory disease usually occurring in synovial tissues and joints, is highly associated with genetic and environmental factors. ORAI1, a gene related to cellular immune system, has been shown to be involved in the pathogenesis of chronic inflammatory diseases and immune disease...

journal_title：Mediators of inflammation

authors： Yen JH,Chang CM,Hsu YW,Lee CH,Wu MS,Hwang DY,Chen BK,Liao HT,Wu MT,Chang WC

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Rodent models suggest that follistatin-like 3 (fstl3) is associated with diabetes and obesity. In humans, plasma fstl3 is reduced with gestational diabetes. In vitro, TNF-α induces fstl3 secretion, which suggests a link to inflammation. OBJECTIVE:To elucidate the association between plasma fstl3 and obesity...

journal_title：Mediators of inflammation

authors： Brandt C,Pedersen M,Rinnov A,Andreasen AS,Møller K,Hojman P,Pedersen BK,Plomgaard P

更新日期：2014-01-01 00:00:00

abstract：:The recently discovered IL-33 as an IL-1 cytokine family member has been proved to be specifically released from osteonecrotic bones. We aimed to investigate the potential role of IL-33 in the development of osteonecrosis of femoral head (ONFH). Forty patients diagnosed with ONFH and forty age-, sex-, and body mass in...

journal_title：Mediators of inflammation

authors： Ma J,Guo W,Li Z,Wang B,Li S,Wang P

更新日期：2017-01-01 00:00:00

abstract：:S. epidermidis is responsible for biofilm-related nonunions. This study compares the response to S. epidermidis-infected fractures in rats systemically or locally injected with vancomycin or bone marrow mesenchymal stem cells (BMSCs) in preventing the nonunion establishment. The 50% of rats receiving BMSCs intravenous...

journal_title：Mediators of inflammation

authors： Lovati AB,Drago L,Bottagisio M,Bongio M,Ferrario M,Perego S,Sansoni V,De Vecchi E,Romanò CL

更新日期：2016-01-01 00:00:00

abstract：:The development of an acidic tissue environment is a hallmark of a variety of inflammatory processes and solid tumors. However, little attention has been paid so far to analyze the influence exerted by extracellular pH on the immune response. Tissue acidosis (pH 6.0 to 7.0) is usually associated with the course of inf...

journal_title：Mediators of inflammation

authors： Erra Díaz F,Dantas E,Geffner J

更新日期：2018-12-30 00:00:00