Incidence and impact of false-positive urine pneumococcal antigen testing in hospitalized patients.

Abstract:

OBJECTIVES:Immunochromatographic urine pneumococcal antigen testing (ICT) has become a common diagnostic tool for those presenting with possible invasive pneumococcal disease. The incidence and clinical impact of ICT false-positivity on hospitalized patients has not been assessed outside of specific patient subpopulations. ICT performance needs to be assessed in a real-world clinical setting. This study aims to describe the incidence and clinical impact of ICT false-positivity in a hospital setting over a 19-month period. METHODS:A retrospective cohort study was performed to assess the incidence of false-positive (FP) ICT among hospitalized patients from November 21, 2007 to June 30, 2009. The primary objective was to describe the incidence of FP ICT results. The secondary objective was to describe what clinical impact, if any, could be attributed to FP ICT results. RESULTS:During the study period, 52 positive ICT results were obtained, of which 5 (9.6%) were deemed falsely positive. Interestingly, two of the 5 FP results were from patients who had received 23-valent pneumococcal vaccine (PPV) in the 2 days prior to ICT. The management of all 5 patients was impacted by the FP results through unnecessary antimicrobial treatment and/or deferral of further clinical evaluation. CONCLUSION:Health care providers should be aware of the potential for ICT FP and should order and interpret these tests within an informed clinical framework.

journal_name

South Med J

journal_title

Southern medical journal

authors

Ryscavage PA,Noskin GA,Bobb A,Bardowski L,Zembower TR

doi

10.1097/SMJ.0b013e3182273b82

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

593-7

issue

8

eissn

0038-4348

issn

1541-8243

pii

00007611-201108000-00011

journal_volume

104

pub_type

杂志文章
  • Effect of physician education and patient counseling on inpatient nonsurgical percutaneous feeding tube placement rate, indications, and outcome.

    abstract:BACKGROUND:The decision to place a percutaneous feeding tube (PFT) in patients who are at the end of life is multidimensional and often complicated. We assessed the effect of physician education and counseling for patients and their surrogates on inpatient nonsurgical (endoscopic and radiologic) PFT placement rates, in...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/SMJ.0b013e3181c9800f

    authors: Swaminath A,Longstreth GF,Runnman EM,Yang SJ

    更新日期:2010-02-01 00:00:00

  • Legislators' views on tobacco policy: are there regional differences in Kentucky?

    abstract:BACKGROUND:Tobacco-growing states have few tobacco control laws, which are relatively weak compared with those in non-tobacco-growing states. Region of the country has been shown to be a predictor of legislators' intentions to vote for cigarette tax increases. METHODS:A total of 116 lawmakers (84%) participated in fac...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:

    authors: Hahn EJ,Rayens MK

    更新日期:2002-03-01 00:00:00

  • Hyperammonemia: the silent killer.

    abstract::Nitrogen, derived from breakdown of dietary amino acids as ammonia, is normally converted to urea and excreted. Impairment in the conversion process (called the urea cycle) can occur, either as a consequence of primary genetic defects or through secondary suppression of enzyme activity. Either process results in hyper...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199307000-00004

    authors: Miga DE,Roth KS

    更新日期:1993-07-01 00:00:00

  • Excessive fetal activity: another worrisome sign?

    abstract::Documented fetal inactivity is strongly suggestive of fetal jeopardy, but the significance of excessive activity over a prolonged period has not been reported. Using data gathered from fetal movement charts recorded by 931 patients, fetal hyperactivity was defined statistically as 40 or more movements perceived per ho...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198302000-00005

    authors: Rayburn WF,Rayburn PR,Gabel LL

    更新日期:1983-02-01 00:00:00

  • Rickets in premature infants fed different formulas.

    abstract::To study the role of formula as a cause of rickets, we randomly assigned 46 very-low-birth-weight (VLBW) infants (less than or equal to 1,500 gm) to one of three groups receiving either Isomil, a soy isolate formula, Similac with Iron, a common milk-based formula, or Similac 24 LBW, a hypercaloric milk-based formula d...

    journal_title:Southern medical journal

    pub_type: 临床试验,杂志文章

    doi:10.1097/00007611-198401000-00005

    authors: Kulkarni PB,Dorand RD,Bridger WM,Payne JH 3rd,Montiel DC,Hill JG

    更新日期:1984-01-01 00:00:00

  • Patient with markedly elevated CA 19-9 not associated with malignancy.

    abstract::A 66-year-old white male presented with jaundice, pruritus, and a 30-pound weight loss over two months. Physical examination revealed scleral icterus. Laboratory evaluation revealed ALT 161 U/L, AST 290 U/L, alkaline phosphatase 2004 U/L, GGT 2,552 U/L, total bilirubin 10.2 mg/dL, and a carbohydrate antigen 19-9 (CA 1...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/01.smj.0000202695.97123.2b

    authors: Lowe D,Lee J,Schade R,Chaudhary A

    更新日期:2006-03-01 00:00:00

  • Detecting ductal shunting in premature infants by range-gated Doppler echocardiography.

    abstract::Range-gated pulsed Doppler echocardiography has been reported to be a useful noninvasive bedside technic for detecting ductal left-to-right shunting in premature infants. We studied 30 premature infants with a birth weight of less than 1,500 gm, using a 5 MHz system developed by Advanced Technology Laboratories. An um...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198109000-00023

    authors: Rees A,Elbl F,Solinger R,Gattinella J,Lambert L,Cook L

    更新日期:1981-09-01 00:00:00

  • Water sanitation practices on the Texas-Mexico border: implications for physicians on both sides.

    abstract::With the epidemic of cholera in South and Central America and reports of cholera in the Northern Hemisphere in Mexico, increasing concern focuses on sanitation problems along the border between the United States and Mexico. It is feared that binationally shared water supplies are threatened or contaminated by sewage a...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199211000-00003

    authors: Cech I,Essman A

    更新日期:1992-11-01 00:00:00

  • Abdominal pain resulting from cerebrospinal fluid pseudocyst and cholelithiasis.

    abstract::Patients treated with ventriculoperitoneal (VP) shunt procedures for hydrocephalus may have abdominal pain related to complications stemming from the shunt tubing itself or to other intra-abdominal disease. In patients with VP shunts, usually children, lack of absorption of cerebrospinal fluid (CSF) may produce a pain...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199208000-00014

    authors: Engelhard HH,Miller FB

    更新日期:1992-08-01 00:00:00

  • Sedimentation level in intracerebral hematoma in patients receiving anticoagulation therapy.

    abstract::We have described two cases of spontaneous intracerebral hematoma, characterized by sedimentation level seen on unenhanced cerebral CT, in patients receiving anticoagulation therapy. Anticoagulation or coagulopathy may be important in producing sedimentation levels. The "sedimentation level" is a more accurate term th...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199310000-00020

    authors: Huang TY,Ahn SS

    更新日期:1993-10-01 00:00:00

  • Extra-adrenal myelolipoma: report of two cases.

    abstract::Myelolipomas are benign tumors composed of an admixture of mature adipose tissue and normal hematopoietic cells. The vast majority occur within the adrenal glands, but several extra-adrenal myelolipomas (EAMLs) have been reported. The typical EAML is a solitary, well-defined mass within the abdomen, most commonly in t...

    journal_title:Southern medical journal

    pub_type: 杂志文章,评审

    doi:10.1097/00007611-199506000-00008

    authors: Prahlow JA,Loggie BW,Cappellari JO,Scharling ES,Teot LA,Iskandar SS

    更新日期:1995-06-01 00:00:00

  • Benign familial neonatal convulsions.

    abstract::Two siblings had frequent seizures from the second and third day of life until one week and seven months, respectively. The mother, grandmothers, and three other family members were similarly affected. Known causes of neonatal seizures were excluded. The condition is inherited as an autosomal dominant trait. Its etiol...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198205000-00038

    authors: Giacoia GP

    更新日期:1982-05-01 00:00:00

  • Rocky Mountain spotted fever: gastrointestinal and laboratory manifestations.

    abstract::Sixty-six cases of serologically documented Rocky Mountain spotted fever (RMSF) from North Carolina are reviewed. Gastrointestinal manifestations were present in 80% of these patients. Because other common expressions of RMSF occasionally do not accompany severe gastrointestinal dysfunction, improper diagnosis and the...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-197806000-00007

    authors: Middleton DB

    更新日期:1978-06-01 00:00:00

  • Factors Affecting Patient Adherence to Lung Cancer Screening.

    abstract:OBJECTIVES:The National Lung Screening Trial (NLST) demonstrated a 20% reduction in mortality with low-dose computed tomography (CT) for lung cancer screening (LCS). The NLST found the greatest benefit to LCS for patients who underwent annual screening for a full 3-year follow-up period. The adherence to serial imaging...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.14423/SMJ.0000000000001167

    authors: Bellinger C,Foley K,Genese F,Lampkin A,Kuperberg S

    更新日期:2020-11-01 00:00:00

  • Surgical treatment of anterior diaphragmatic hernia.

    abstract::Of ten patients with anterior diaphragmatic hernia treated by operation, only three had shortness of breath and chest pain. The remainder of the patients were referred to us because of a roentgenographic abnormality. All patients have had follow-up of between six months and 11 years without recurrence. Surgical repair...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198203000-00008

    authors: Saha SP,Mayo P,Long GA

    更新日期:1982-03-01 00:00:00

  • Use of statins in patients with chronic hepatitis C.

    abstract::Hepatitis C is a leading cause of liver failure and transplantation in the United States and a major public health issue. Studies have shown that patients with hepatitis C are at an increased risk of cardiovascular disease, which make statins of particular benefit in this patient population. However, the National Chol...

    journal_title:Southern medical journal

    pub_type: 杂志文章,评审

    doi:10.1097/SMJ.0b013e3181f0c6b4

    authors: Andrus MR,East J

    更新日期:2010-10-01 00:00:00

  • Grip strength before and after carpal tunnel decompression.

    abstract::We prospectively studied preoperative and postoperative grip and pinch strength in 21 patients having 30 consecutive median nerve decompressions for carpal tunnel syndrome. All procedures were done by one surgeon. Each hand operated on served as its own control and was studied by the same therapist preoperatively and ...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199209000-00009

    authors: Young VL,Logan SE,Fernando B,Grasse P,Seaton M,Young AE

    更新日期:1992-09-01 00:00:00

  • Small bowel obstruction and previous gynecologic surgery.

    abstract::We reviewed the cases of women admitted to LSU Medical Center in Shreveport with the diagnosis of "small bowel obstruction" from Jan 1, 1975 to June 30, 1981. Review of the charts of patients who had exploratory laparotomy for relief of the obstruction showed that 83% of them had had previous abdominal surgery. Furthe...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198311000-00005

    authors: Ratcliff JB,Kapernick P,Brooks GG,Dunnihoo DR

    更新日期:1983-11-01 00:00:00

  • Scleroderma: developments from Osler to the present.

    abstract::The clinical entity of progressive systemic sclerosis (PSS, or scleroderma) has remained unchanged since Osler's first description in 1892. Several related or overlap syndromes have now been recognized, which may afford some insight into etiologic events in the development of PSS. As yet, the cause of PSS remains elus...

    journal_title:Southern medical journal

    pub_type: 杂志文章,评审

    doi:10.1097/00007611-198006000-00027

    authors: Cunningham PH,Andrews BS,Davis JS 4th

    更新日期:1980-06-01 00:00:00

  • Prevalence of lead intoxication in urban, adult medical inpatients.

    abstract::Medical inpatients in inner-city hospitals have both potentially lead-related disorders and potential lead exposure. To see whether there is substantial unexpected lead intoxication in this population, we did a cross-sectional study of 117 consecutively admitted patients to a general medical ward of an inner-city univ...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199605000-00003

    authors: Kilmarx PH,Allen DW,Brancati FL

    更新日期:1996-05-01 00:00:00

  • Treatments for Alzheimer disease.

    abstract::As our population ages, the incidence and prevalence of Alzheimer disease (AD) will increase dramatically. A number of therapies have been investigated for the treatment and prevention of AD. Clinicians should be prepared to provide evidence-based answers to inquiries regarding AD treatment. There is insufficient evid...

    journal_title:Southern medical journal

    pub_type: 杂志文章,评审

    doi:10.1097/01.SMJ.0000166671.86815.C1

    authors: Potyk D

    更新日期:2005-06-01 00:00:00

  • Influenza vaccination acceptance and refusal rates among health care personnel.

    abstract:OBJECTIVES:The primary aim of this study was to determine reasons why health care personnel (HCP) in a public health department chose or refused free influenza vaccinations offered at the worksite. METHODS:In an internal review board-approved study, we offered, through a health nurse at the site, self-administered sur...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/SMJ.0b013e3181eda3d5

    authors: Millner VS,Eichold BH 2nd,Franks RD,Johnson GD

    更新日期:2010-10-01 00:00:00

  • Hemorrhagic tamponade due to cardiac angiosarcoma.

    abstract::Prognosis of angiosarcoma, the most common primary malignant cardiac tumor, is very poor. An early detection and treatment may extend survival beyond one year. Newer imaging modalities, including magnetic resonance imaging (MRI), play an important role in the evaluation of cardiac masses. The case of a man admitted to...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/SMJ.0b013e3181ecfb64

    authors: Vautrin E,Barone-Rochette G,Thony F,Lantuejoul S,Towie DH,Bach V,Baguet JP

    更新日期:2010-10-01 00:00:00

  • Mobile Health (mHealth) Use or Non-Use by Residents of West Virginia.

    abstract:OBJECTIVE:To compare mobile health (mHealth) usage by residents of West Virginia with national estimates. METHODS:Pew Research Center data from its Internet and American Life Project were accessed for secondary data analysis. These data, available to the public, are a probability sample of Internet use in the United S...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.14423/SMJ.0000000000000879

    authors: Giacobbi P Jr,Cushing P,Popa A,Haggerty T,Hansell A,Sedney C

    更新日期:2018-10-01 00:00:00

  • Splenoportography--a valuable diagnostic technic, revisited.

    abstract::The value of splenoportography in evaluating patients with portal hypertension was assessed. The technic was found to be useful in estimating portal-venous pressure, ruling out portal vein thrombosis, evaluating the superior mesenteric and portal veins as to their suitability for shunt procedures, and defining anatomy...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-197710000-00017

    authors: Kogutt MS,Jander HP

    更新日期:1977-10-01 00:00:00

  • Microbiologic basis for the rational use of prophylactic antibiotics.

    abstract::Appropriate use of antibiotics is enhanced by the effective application of data on antimicrobial susceptibility. A number of methods are currently available for routine determination of susceptibilities, including agar dilution, broth dilution, agar diffusion, and several semiautomated methods. If susceptibility testi...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:

    authors: Moellering RC Jr,Kunz LJ,Poitras JW,Cameron M,Mercier BA

    更新日期:1977-10-01 00:00:00

  • Acetaminophen hepatotoxicity in the alcoholic.

    abstract::In a retrospective review from 1987 to 1989, we identified seven alcoholics who had severe acute hepatocellular injury soon after using acetaminophen for therapeutic purposes and who had no suicidal intent. All had markedly elevated serum transaminase values (aspartate aminotransferase greater than 4000 U/L) and prolo...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199009000-00017

    authors: Wootton FT,Lee WM

    更新日期:1990-09-01 00:00:00

  • Malignant fibrous histiocytoma arising from the superficial femoral artery.

    abstract::Primary sarcomatous arterial tumors are rare. We have reported a case of malignant fibrous histiocytoma in an elderly woman successfully treated by resection of the involved femoral vessel and reconstruction with a PTFE graft. The long-term result in this patient is presently uncertain. ...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199202000-00030

    authors: Feldtman RW,Cox CS Jr,Nirgiotis J,Guarjardo M

    更新日期:1992-02-01 00:00:00

  • Rhegmatogenous retinal detachment complicating diabetic retinopathy.

    abstract::Retinal detachment complicating proliferative diabetic retinopathy is being recognized with increasing frequency. Although one type of detachment is tractional and requires vitrectomy for hopeful repair, the other variety of detachment is rhegmatogenous. The rhegmatogenous form of retinal detachment does not generally...

    journal_title:Southern medical journal

    pub_type: 杂志文章,评审

    doi:10.1097/00007611-197810000-00007

    authors: Humphrey WT

    更新日期:1978-10-01 00:00:00

  • Hypothyroidism with coexistent asthma: problems in management.

    abstract::This case study illustrates the relationship between hypothyroidism and bronchial asthma. As seen here, even slow and cautious restoration of the euthyroid state may lead to problems in the management of asthma. Thus routine or aggressive replacement therapy for thyroid hypofunction in the asthmatic population is not ...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198403000-00037

    authors: Rowe MS,MacKechnie HL

    更新日期:1984-03-01 00:00:00