Abstract:
:Unfertilized ova from Shad, a North Atlantic herring, contains a cytostatic inhibitor of T lymphocyte blastogenesis. The inhibitor has an estimated molecular weight of 10,000-30,000 Da, is heat stable, non dialyzable, and resistant to protease digestion and periodate oxidation. Although the inhibitor functions at an early metabolic event in T lymphocyte mitogenesis, it does not appear to interfere with thymidine transport, antagonize lectin binding to lymphocyte surface receptors, or interfere with the function of an essential serum component in the cell culture media.
journal_name
Life Scijournal_title
Life sciencesauthors
Sheid B,Nobiletti JB,Prat JCdoi
10.1016/0024-3205(90)90336-psubject
Has Abstractpub_date
1990-01-01 00:00:00pages
1367-72issue
19eissn
0024-3205issn
1879-0631pii
0024-3205(90)90336-Pjournal_volume
46pub_type
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