Genotyping Neisseria gonorrhoeae gyrA and penA antimicrobial genes from remnant Neisseria gonorrhoeae positive Cepheid Xpert® clinical specimens - A feasibility study.

Abstract:

:Neisseria gonorrhoeae (NG) has developed resistance to most antibiotics, making it increasingly difficult to treat. Previous studies have predicted antimicrobial NG susceptibility based on the antimicrobial gene target DNA gyrase subunit A (gyrA) codon serine 91 and the penicillin-binding protein 2 (penA) using Roche Cobas® and Hologic APTIMA™ clinical specimens. We studied whether similar methods could be used on remnant NG-positive Cepheid Xpert® specimens.

journal_name

J Microbiol Methods

authors

Qadir S,Ellis O,Keizur EM,Stafylis C,Cortado R,Klausner JD,Adolescent Trials Network (ATN) CARES Team.

doi

10.1016/j.mimet.2019.105783

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

105783

eissn

0167-7012

issn

1872-8359

pii

S0167-7012(19)30563-9

journal_volume

168

pub_type

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