The prognostic value of NRF2 in breast cancer patients: a systematic review with meta-analysis.

abstract：BACKGROUND:The Van Nuys Prognostic Index (VNPI) is a simple score for predicting the risk of local recurrence (LR) in patients with Ductal Carcinoma In Situ (DCIS) conservatively treated. This score combines three independent predictors of Local Recurrence. The VNPI has recently been updated with the addition of age as...

journal_title：Breast cancer research and treatment

authors： Di Saverio S,Catena F,Santini D,Ansaloni L,Fogacci T,Mignani S,Leone A,Gazzotti F,Gagliardi S,De Cataldis A,Taffurelli M

更新日期：2008-06-01 00:00:00

abstract：PURPOSE:Estrogen exposure is involved in both breast cancer susceptibility and the prognosis in patients with breast cancer. Aromatase is involved in the production of estrogens, and altered expression of it might be associated with the prognosis. The aim of this study was to examine the effect of single nucleotide pol...

journal_title：Breast cancer research and treatment

authors： Fasching PA,Loehberg CR,Strissel PL,Lux MP,Bani MR,Schrauder M,Geiler S,Ringleff K,Oeser S,Weihbrecht S,Schulz-Wendtland R,Hartmann A,Beckmann MW,Strick R

更新日期：2008-11-01 00:00:00

abstract：:Breast cancer is one of the most frequently diagnosed cancers in women in France, but its aetiology remains unknown. Viruses including Epstein-Barr virus (EBV), a human equivalent of murine mammary tumour virus (MMTV) and human papillomavirus (HPV) have been detected in benign breast tissues and breast tumours and are...

journal_title：Breast cancer research and treatment

authors： de Cremoux P,Thioux M,Lebigot I,Sigal-Zafrani B,Salmon R,Sastre-Garau X,Institut Curie Breast Group.

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:Although quality of life (QoL) improves over time for most breast cancer survivors (BCS), BCS may show different patterns of QoL. This study sought to identify distinct QoL trajectories among BCS and to examine characteristics associated with trajectory group membership. METHODS:BCS (N = 653) completed baselin...

journal_title：Breast cancer research and treatment

authors： Goyal NG,Levine BJ,Van Zee KJ,Naftalis E,Avis NE

更新日期：2018-05-01 00:00:00

abstract：:MicroRNAs play a role in breast cancer development and progression by post-transcriptional repression of the expression of important genes, such as the tumor suppressor gene phosphatase and tensin homolog (PTEN). The focus of the current study was to examine the diagnostic potential of circulating cell-free microRNAs ...

journal_title：Breast cancer research and treatment

authors： Schwarzenbach H,Milde-Langosch K,Steinbach B,Müller V,Pantel K

更新日期：2012-08-01 00:00:00

abstract：:The pharmacokinetics of free and different liposomal formulations of hexadecylphosphocholine (HPC) was investigated in tumor-bearing (human mammary tumor MaTu) and tumor-free mice after intravenous and intraperitoneal administration. The levels of HPC were evaluated at different times in serum, normal tissues, and tum...

journal_title：Breast cancer research and treatment

authors： Arndt D,Zeisig R,Fichtner I,Teppke AD,Fahr A

更新日期：1999-11-01 00:00:00

abstract：:Progression of breast cancer from an estrogen-dependent, slowly growing tumor amenable to tamoxifen treatment to an aggressive, metastatic, estrogen-independent phenotype has been mimicked by the transfection of MCF-7 breast carcinoma cells with fibroblast growth factors 1 or 4. FGF-transfected cells are aggressively ...

journal_title：Breast cancer research and treatment

authors： McLeskey SW,Zhang L,Kharbanda S,Kurebayashi J,Lippman ME,Dickson RB,Kern FG

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:The use of adjuvant radiotherapy (RT) in the management of ductal carcinoma in situ (DCIS) is increasing. Left-sided breast irradiation may involve exposure of the heart to ionising radiation, increasing the risk of ischemic heart disease (IHD). We examined the incidence of IHD in a population-based cohort of w...

journal_title：Breast cancer research and treatment

authors： Wadsten C,Wennstig AK,Garmo H,Nilsson G,Blomqvist C,Holmberg L,Fredriksson I,Wärnberg F,Sund M

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:Breast cancer brain metastases (BCBM) are becoming an increasingly common diagnosis due to improved systemic control and more routine surveillance imaging. Treatment continues to require a multidisciplinary approach managing systemic and intracranial disease burden. Although, improvements have been made in the ...

journal_title：Breast cancer research and treatment

authors： Mills MN,Figura NB,Arrington JA,Yu HM,Etame AB,Vogelbaum MA,Soliman H,Czerniecki BJ,Forsyth PA,Han HS,Ahmed KA

更新日期：2020-04-01 00:00:00

abstract：:Gene fusions have long been considered principally as the oncogenic events of hematologic malignancies, but have recently gained wide attention in solid tumors due to several milestone discoveries and the advancement of deep sequencing technologies. With the progress in deep sequencing studies of breast cancer transcr...

journal_title：Breast cancer research and treatment

authors： Veeraraghavan J,Ma J,Hu Y,Wang XS

更新日期：2016-07-01 00:00:00

abstract：MAIN PURPOSE:Germline BRCA mutations (BRCAm) strongly influence the risk of developing breast cancer. This study aimed to understand the role of BRCAm testing in affected individuals and to assess its impact on the outcome of BRCAm carriers compared to non-carriers (BRCAwt) with breast cancer. RESEARCH QUESTION:The re...

journal_title：Breast cancer research and treatment

authors： Stenehjem DD,Telford C,Unni SK,Bauer H,Sainski A,Deka R,Schauerhamer MB,Ye X,Tak CR,Ma J,Dalvi TB,Gutierrez L,Kaye JA,Tyczynski JE,Brixner DI,Biskupiak JE

更新日期：2021-01-03 00:00:00

abstract：PURPOSE:Cytokine milieu of tumor microenvironment affects tumorigenesis in breast cancer. The aim of the present study was to investigate the potential association of functional single nucleotide polymorphisms (SNPs) in TNF-LTA locus with breast cancer. METHODS:The study included 127 individuals comprising 40 breast c...

journal_title：Breast cancer research and treatment

authors： Kohaar I,Tiwari P,Kumar R,Nasare V,Thakur N,Das BC,Bharadwaj M

更新日期：2009-03-01 00:00:00

abstract：:Genome-Wide Association Studies have identified several loci associated with breast cancer (BC) in populations of different ethnic origins. One of the strongest associations was found in the FGFR2 gene, and MAP3K1 has been proposed as a low-penetrance BC risk factor. In this study, we evaluated the associations among ...

journal_title：Breast cancer research and treatment

authors： Jara L,Gonzalez-Hormazabal P,Cerceño K,Di Capua GA,Reyes JM,Blanco R,Bravo T,Peralta O,Gomez F,Waugh E,Margarit S,Ibañez G,Romero C,Pakomio J,Roizen G

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:Ki-67 has been clinically validated for risk assessment in breast cancer, but the analytical validation and cutpoint-definition remain a challenge. Intraclass correlation coefficients (ICCs) are a statistical parameter for Ki-67 interobserver performance. However, the maximum degree of variance among pathologis...

journal_title：Breast cancer research and treatment

authors： Denkert C,Budczies J,Regan MM,Loibl S,Dell'Orto P,von Minckwitz G,Mastropasqua MG,Solbach C,Thürlimann B,Mehta K,Blohmer JU,Colleoni M,Müller V,Klauschen F,Ataseven B,Engels K,Kammler R,Pfitzner BM,Dietel M,Fasching

更新日期：2019-08-01 00:00:00

abstract：:Aberrant expressions of the neuronal protein synuclein gamma (SNCG) in malignant mammary epithelial cells are strongly associated with the progression of breast cancer. SNCG is not expressed in normal breast tissues but abundantly expressed in a high percentage of invasive and metastatic breast carcinomas. Several stu...

journal_title：Breast cancer research and treatment

authors： Inaba S,Li C,Shi YE,Song DQ,Jiang JD,Liu J

更新日期：2005-11-01 00:00:00

abstract：:Knowledge about long-term consequences of breast cancer treatment on shoulder and arm function and volume in stages I-II breast cancer survivors is limited. The effects of shoulder-arm function shortly after surgery on long-term function are unknown. One hundred and ninety-four women were examined pre-surgery (T0) and...

journal_title：Breast cancer research and treatment

authors： Kootstra JJ,Dijkstra PU,Rietman H,de Vries J,Baas P,Geertzen JH,Hoekstra HJ,Hoekstra-Weebers JE

更新日期：2013-05-01 00:00:00

abstract：:It is common belief among physicians the idea that breast cancer was not diagnosed centuries ago. Nevertheless, there are reports suggesting that old masters and even common people knew this dramatic disease. In the 16th and 17th centuries, famous artists painted things exactly as they saw them. This allows the detect...

journal_title：Breast cancer research and treatment

authors： Grau JJ,Estrach T

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:Radiotherapy (RT) constitutes an important part of breast cancer treatment. However, triple negative breast cancers (TNBC) exhibit remarkable resistance to most therapies, including RT. Developing new ways to radiosensitize TNBC cells could result in improved patient outcomes. The M2 isoform of pyruvate kinase ...

journal_title：Breast cancer research and treatment

authors： Zhang L,Bailleul J,Yazal T,Dong K,Sung D,Dao A,Gosa L,Nathanson D,Bhat K,Duhachek-Muggy S,Alli C,Dratver MB,Pajonk F,Vlashi E

更新日期：2019-11-01 00:00:00

abstract：:Tamoxifen citrate is a synthetic antiestrogen that provides survival benefit when given as adjuvant treatment in postmenopausal women with breast cancer. Venous thrombophlebitis may complicate tamoxifen treatment at a rate of approximately one per 800 treatment-years. To explore the possible procoagulant effects assoc...

journal_title：Breast cancer research and treatment

authors： Mamby CC,Love RR,Feyzi JM

更新日期：1994-01-01 00:00:00

abstract：:Although a wealth of research has focused on the influence of diet on breast cancer risk, the relationships between dietary factors and tumor characteristics of breast cancer, like estrogen receptor (ER) status, are not well characterized. In a case-case study, we evaluated self-reported dietary intake for five indivi...

journal_title：Breast cancer research and treatment

authors： Jakovljevic J,Touillaud MS,Bondy ML,Singletary SE,Pillow PC,Chang S

更新日期：2002-09-01 00:00:00

abstract：:12 women with primary breast cancer underwent somatostatin receptor scintigraphy (SRS) with 111In-DTPA-D-Phe1-octreotide. The tumour sizes varied between 2 and 5 cm and were all, except one, palpable at clinical examination. Tumour biopsies were taken with additional sampling from normal breast tissue, fat, muscle, ax...

journal_title：Breast cancer research and treatment

authors： Skånberg J,Ahlman H,Benjegård SA,Fjälling M,Forssell-Aronsson EB,Hashemi SH,Nilsson O,Suurkula M,Jansson S

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Vinorelbine (Navelbin; N) has proven to be active in patients with advanced breast cancer (ABC) and cyclophosphamide (C) and epirubicin (Epiadriamycin: E) are still among the main cytostatic agents against this tumor. On this basis was carried out a study to determine the activity and toxicity of the combina...

journal_title：Breast cancer research and treatment

authors： Esteban E,de Sande G,Puertas J,Fra J,Palacio I,Vieitez JM,Fernández JL,Muñiz I,Modollel A,Carrasco J,Sala M,Lacave AJ

更新日期：2000-07-01 00:00:00

abstract：:Manganese superoxide dismutase (MnSOD) is known to play a role in cancer. MnSOD exerts a tumor suppressive effect in estrogen-dependent human breast cancer cells. In the present study we investigated the in vitro role of MnSOD in the growth of some aggressive and highly metastatic estrogen-independent breast cancer ce...

journal_title：Breast cancer research and treatment

authors： Kattan Z,Minig V,Leroy P,Dauça M,Becuwe P

更新日期：2008-03-01 00:00:00

abstract：:Metformin may exert anti-cancer effects through indirect (insulin-mediated) or direct (insulin-independent) mechanisms. We report results of a neoadjuvant "window of opportunity" study of metformin in women with operable breast cancer. Newly diagnosed, untreated, non-diabetic breast cancer patients received metformin ...

journal_title：Breast cancer research and treatment

authors： Niraula S,Dowling RJ,Ennis M,Chang MC,Done SJ,Hood N,Escallon J,Leong WL,McCready DR,Reedijk M,Stambolic V,Goodwin PJ

更新日期：2012-10-01 00:00:00

abstract：:Eighty-five breast cancer specimens were processed as part of a program in tumor acquisition, propagation, and preservation for biotherapy. Nine long-term culture cell lines were developed. Four cell lines were from solid tumor metastases, two lines were from pleural fluid specimens, and three were from xenograft tumo...

journal_title：Breast cancer research and treatment

authors： Lewko WM,Vaghmar R,Hubbard D,Moore M,He YJ,Chang L,Husseini S,Wallwork K,Thurman GB,Oldham RK

更新日期：1990-12-01 00:00:00

abstract：:The complexity of breast cancer biology makes it challenging to analyze large datasets of clinicopathologic and molecular attributes, toward identifying the key prognostic features and producing systems capable of predicting which patients are likely to relapse. We applied machine-learning techniques to analyze a set ...

journal_title：Breast cancer research and treatment

authors： Asgarian N,Hu X,Aktary Z,Chapman KA,Lam L,Chibbar R,Mackey J,Greiner R,Pasdar M

更新日期：2010-06-01 00:00:00

abstract：:After more than 100 reported randomized trials of systemic adjuvant therapy in breast cancer, it is clear that this therapy will prolong the time to recurrence and the survival time significantly, at least in some patient subsets. But there is less than complete agreement as to which subsets, which therapies, how much...

journal_title：Breast cancer research and treatment

authors： Henderson IC

更新日期：1989-10-01 00:00:00

abstract：PURPOSE:New biomarkers are emerging to predict recurrence risk in women with early-stage breast cancer. High Oncotype DX Recurrence Score® (RS) is associated with worse disease-free and overall survival. Similarly, circulating tumor cells (CTCs, blood) and disseminated tumor cells (DTCs, bone marrow) have prognostic va...

journal_title：Breast cancer research and treatment

authors： Singh P,Tevis SE,Hall CS,Meas S,Hwang RF,Lucci A

更新日期：2020-12-01 00:00:00

abstract：:The use of molecular components from both normal and neoplastic breast tissue as markers for breast tumors has long been recognized as of major potential for breast cancer diagnosis, and has been an area of active research. Recent developments in immunological approaches have further stimulated this field by permittin...

journal_title：Breast cancer research and treatment

authors： Ceriani R,Anderson EP

更新日期：1985-01-01 00:00:00

abstract：:Transforming growth factor-beta (TGFB) is a potent inhibitor of normal epithelial cell proliferation, and may be one of the regulatory factors that are perturbed during tumor development. While many tumor cell lines no longer respond to the inhibitory effects of TGFB due to a reduction or absence of the type II recept...

journal_title：Breast cancer research and treatment

authors： Barlow J,Yandell D,Weaver D,Casey T,Plaut K

更新日期：2003-05-01 00:00:00