The American self and the long march to legal equality.

abstract：:Obesity is a phenotype resulting from a series of causative factors with a variable risk of complications. Etiologic diversity requires personalized prevention and treatment. Imaging procedures offer the potential to investigate the interplay between organs and pathways underlying energy intake and consumption in an i...

journal_title：Annals of the New York Academy of Sciences

authors： Iozzo P

更新日期：2015-09-01 00:00:00

abstract：:The acquisition of both speech and music uses general principles: learners extract statistical regularities present in the environment. Yet, individuals who suffer from congenital amusia (commonly called tone-deafness) have experienced lifelong difficulties in acquiring basic musical skills, while their language abili...

journal_title：Annals of the New York Academy of Sciences

authors： Peretz I,Saffran J,Schön D,Gosselin N

更新日期：2012-04-01 00:00:00

abstract：:Cowdria ruminantium is an obligate intracellular rickettsial pathogen which is responsible for a tick-borne disease of domestic and wild ruminants called heartwater or cowdriosis. Although several genes have been cloned and partially sequenced, the genome size, gross structure, and organization of the C. ruminantium g...

journal_title：Annals of the New York Academy of Sciences

authors： de Villiers EP,Brayton KA,Zweygarth E,Allsopp BA

更新日期：1998-06-29 00:00:00

abstract：:Hematopoietic development in the mammal can be represented as a numerically expanding hierarchy of cell populations that are progressively restricted in their self-renewal and differentiation abilities. Classical functional studies have now been extended to provide exact physical descriptions of various stages in the ...

journal_title：Annals of the New York Academy of Sciences

authors： Lemischka I

更新日期：1999-04-30 00:00:00

abstract：:This paper examines the frequency of CIND, the profile of early cognitive deficits in stroke patients, the differences in the profile of cognitive impairment in people with CIND and those with vascular dementia, and the MRI associations of CIND in older stroke patients. ...

journal_title：Annals of the New York Academy of Sciences

authors： Ballard C,Stephens S,McLaren A,Wesnes K,Kenny RA,Burton E,O'Brien J,Kalaria R

更新日期：2002-11-01 00:00:00

abstract：:Amyloid precursor proteins (APP) are a member of a larger family of proteins that include the amyloid precursor-like proteins (APLP) APLPI and APLP2. We have examined the expression and metabolism of APLP2 and document that APLP2 is expressed at high levels in the nervous system and in peripheral tissues. Furthermore,...

journal_title：Annals of the New York Academy of Sciences

authors： Sisodia SS,Thinakaran G,Slunt HH,Kitt CA,Von Koch CS,Reed RR,Zheng H,Price DL

更新日期：1996-01-17 00:00:00

abstract：:alpha-Melanocyte stimulating hormone (alpha-MSH) modulates all forms of inflammation by acting on peripheral inflammatory cells, glial inflammatory cells, and on CNS receptors that activate descending antiinflammatory neural pathways. The multiple actions of this ancient peptide suggest that there is no singular bioch...

journal_title：Annals of the New York Academy of Sciences

authors： Lipton JM,Zhao H,Ichiyama T,Barsh GS,Catania A

更新日期：1999-10-20 00:00:00

abstract：:In this paper, the topic of laminar to turbulent flow transition, as applied to the design of gas turbines, is discussed. Transition comes about when a flow becomes sufficiently unstable that the orderly vorticity structure of the laminar layer becomes randomly oriented. Vorticity with a streamwise component leads to ...

journal_title：Annals of the New York Academy of Sciences

authors： Simon TW,Kaszeta RW

更新日期：2001-05-01 00:00:00

abstract：:Regulation of carbohydrate and fat utilization by skeletal muscle at rest and during exercise has been the subject of investigation since the early 1960s when Randle et al. proposed the so-called glucose-fatty acid cycle to explain the reciprocal relationship between carbohydrate and fat metabolism. The suggested mech...

journal_title：Annals of the New York Academy of Sciences

authors： Jeukendrup AE

更新日期：2002-06-01 00:00:00

abstract：:Undernutrition and inadequate stimulation both negatively influence child health and development and have a long-term impact on school attainment and income. This paper reports data from India and Pakistan looking at how families interact, play with, and feed children; their expectations of growth and development; and...

journal_title：Annals of the New York Academy of Sciences

authors： Lingam R,Gupta P,Zafar S,Hill Z,Yousafzai A,Iyengar S,Sikander S,Haq Zu,Mehta S,Skordis-Worrel J,Rahman A,Kirkwood B

更新日期：2014-01-01 00:00:00

abstract：:It is often proposed that quinolinic acid (QUIN) contributes to the pathophysiology of neuroinflammation because this kynurenine pathway metabolite is a selective agonist of N-methyl-D-aspartate (NMDA) receptors, and both its brain tissue and cerebrospinal fluid concentrations increase markedly with inflammation. Howe...

journal_title：Annals of the New York Academy of Sciences

authors： Obrenovitch TP

更新日期：2001-06-01 00:00:00

abstract：:Hereditary adrenal pheochromocytoma is caused by germline mutations in RET, VHL, SDHB, SDHD, and NF1. As these genes differ in function, so may their pheochromocytoma phenotypes, suggesting gene-specific patterns of age-related progression to pheochromocytoma. This possibility was explored for gene carriers with a lif...

journal_title：Annals of the New York Academy of Sciences

authors： Machens A,Brauckhoff M,Gimm O,Dralle H

更新日期：2006-08-01 00:00:00

abstract：:The formation of bone is a continual process in vertebrate development, initiated during fetal development and persisting in adulthood in the form of remodeling and repair. The remarkable capacity of skeletal tissues to regenerate has led to the hypothesis that the molecular signaling pathways regulating skeletogenesi...

journal_title：Annals of the New York Academy of Sciences

authors： Ferguson CM,Miclau T,Hu D,Alpern E,Helms JA

更新日期：1998-10-23 00:00:00

abstract：:Bioterrorism includes possible use of Weapons of Mass Destruction (WMD), preferably biological agents, by non-state terrorist groups as well as criminal clusters. The threat from terrorists to utilize biological agents to achieve goals is not new, but the threshold to realize the threats seems to be lower than previou...

journal_title：Annals of the New York Academy of Sciences

authors： Sandström G

更新日期：2000-01-01 00:00:00

abstract：:The data from our study indicate that the magnitude of occupational disease in New York State is considerable, and that a detailed and comprehensive plan must be initiated and implemented if occupational disease is to be controlled. New York State contains slightly less than 10% of the nation's workforce. A direct lin...

journal_title：Annals of the New York Academy of Sciences

authors： Landrigan PJ,Markowitz S

更新日期：1989-01-01 00:00:00

abstract：:Scleroderma renal crisis (SRC) is a major complication in patients with systemic sclerosis (SSc). SRC occurs during the first 4 years of disease evolution in more than 75% of the cases, almost exclusively in patients with diffuse SSc. Other risk factors, including preceding corticosteroid therapy, have been associated...

journal_title：Annals of the New York Academy of Sciences

authors： Teixeira L,Mahr A,Berezné A,Noël LH,Guillevin L,Mouthon L

更新日期：2007-06-01 00:00:00

abstract：:T cell protein tyrosine phosphatase (TCPTP) dephosphorylates a number of substrates, including JAK-STAT (signal transducer and activator of transcription) signaling proteins, which are activated by interferon (IFN)-γ, a major proinflammatory cytokine involved in conditions such as inflammatory bowel disease. A critica...

journal_title：Annals of the New York Academy of Sciences

authors： Krishnan M,McCole DF

更新日期：2017-10-01 00:00:00

abstract：:Vestibular stimulation by head accelerations always involves multisensory activation of the vestibular, somatosensory, and visual systems. Over the past few years, galvanic vestibular stimulation (GVS) has become increasingly popular for testing vestibular function for clinical and research purposes. Although GVS prov...

journal_title：Annals of the New York Academy of Sciences

authors： Jahn K,Naessl A,Strupp M,Schneider E,Brandt T,Dieterich M

更新日期：2003-10-01 00:00:00

abstract：:In this paper we have reported the results of studies in psychiatric patient groups using the strategy of measuring opioid activity and beta-endorphin (ir) in CSF. Our findings do not lend support to the notion of excess endorphin activity in schizophrenia, but rather suggest the possibility of a decrease in endogenou...

journal_title：Annals of the New York Academy of Sciences

authors： Pickar D,Naber D,Post RM,van Kammen DP,Kaye W,Rubinow DR,Ballenger JC,Bunney WE Jr

更新日期：1982-01-01 00:00:00

abstract：:According to the fetal origin of adult diseases hypothesis, the intrauterine environment through developmental plasticity may permanently influence long-term health and disease. Therefore, intrauterine growth restriction (IUGR), due either to maternal, placental, or genetic factors, may permanently alter the endocrine...

journal_title：Annals of the New York Academy of Sciences

authors： Kanaka-Gantenbein C

更新日期：2010-09-01 00:00:00

abstract：:Fifteen patients with coccidioidal meningitis were treated with high doses of ketoconazole for up to 4 years. Five patients were treated with ketoconazole alone. One clinically failed, one developed hepatotoxicity, and three achieved remission of meningitis. One patient received intrathecal AMB in addition to ketocona...

journal_title：Annals of the New York Academy of Sciences

authors： Graybill JR,Stevens DA,Galgiani JN,Sugar AM,Craven PC,Gregg C,Huppert M,Cloud G,Dismukes WE

更新日期：1988-01-01 00:00:00

abstract：:Insulin resistance has been recognized as the fundamental underlying metabolic defect in the pathogenesis of metabolic syndrome, a clustering of cardiovascular risk factors such as diabetes, hypertension, dyslipidemia, and obesity. Recent studies established that mitochondrial dysfunction is involved in insulin resist...

journal_title：Annals of the New York Academy of Sciences

authors： Lee HK,Park KS,Cho YM,Lee YY,Pak YK

更新日期：2005-05-01 00:00:00

abstract：:The M1 antigens, associated with gastric fucomucin, the early oncofetal precancerous marker for the distal colon, were studied using the immunoperoxidase method in the distal colon. We compared human tumoral mucosa with that of rats during DMH-induced carcinogenesis. In both cases we examined histologically normal muc...

journal_title：Annals of the New York Academy of Sciences

authors： Bara J,Decaens C,Burtin P

更新日期：1983-01-01 00:00:00

abstract：:Chronic purulent rhinosinusitis (CPR) is an inflammatory condition of unknown origin. Although various medical and surgical treatment modalities are available, 5-10% of patients remain refractory. Immune deficiency is one of the underlying risk factors for this disease. Earlier studies demonstrated disturbances in cel...

journal_title：Annals of the New York Academy of Sciences

authors： Dalm VA,de Wit H,Drexhage HA

更新日期：2012-10-01 00:00:00

abstract：:These findings support the hypothesis that a frontal-subcortical abnormality is necessary to produce symptoms of depression (e.g., mood-related signs, behavioral disturbances, neurovegetative signs) in dementia. Behavioral disturbances (e.g., disinhibition, agitation, social withdrawal) were more likely to occur in FL...

journal_title：Annals of the New York Academy of Sciences

authors： Lopez OL,Gonzalez MP,Becker JT,Reynolds CF 3rd,Sudilovsky A,DeKosky ST

更新日期：1995-12-15 00:00:00

abstract：:In recent years, different subphenotypes of obesity have been described, including metabolically healthy obesity (MHO), in which a proportion of obese individuals, despite excess body fat, remain free of metabolic abnormalities and increased cardiometabolic risk. In the absence of a universally accepted set of criteri...

journal_title：Annals of the New York Academy of Sciences

authors： Phillips CM

更新日期：2017-03-01 00:00:00

abstract：:Despite new technological advances in the rehabilitation of audition in profoundly deaf children, auditory training remains a fundamental part of their education. Consequently, it is necessary to learn what kind of stimuli, what kind of auditory tasks, and what kind of learning procedures generate faster and more long...

journal_title：Annals of the New York Academy of Sciences

authors： Rochette F,Bigand E

更新日期：2009-07-01 00:00:00

abstract：:In the pancreatic islets, pituitary adenylate cyclase-activating polypeptide (PACAP) is expressed in beta cells and autonomic nerve terminals; the majority of these nerve terminals are parasympathetic. PACAP binds to three types of G protein-coupled receptors (GPCRs): VPAC1 receptors, VPAC2 receptors, and PAC1 recepto...

journal_title：Annals of the New York Academy of Sciences

authors： Ahrén B

更新日期：2008-11-01 00:00:00

abstract：:I(2) site-selective compounds are known to interact with and inhibit monoamine oxidase (MAO), but it remains unclear as to whether this interaction occurs through an allosteric or competitive interaction. This study used the new selective, irreversible I(2) ligand BU99006, to clarify the relationship between MAO and t...

journal_title：Annals of the New York Academy of Sciences

authors： Paterson LM,Tyacke RJ,Nutt DJ,Hudson AL

更新日期：2003-12-01 00:00:00

abstract：:Indoor air pollution occurs as an undesirable consequence of urbanization, energy conservation, indoor bioaerosol contamination, and use of synthetic materials and new technologies, and has become a worldwide concern. It is important to comprehend not only the diversity of pollutant hazards but also to develop novel m...

journal_title：Annals of the New York Academy of Sciences

authors： Brooks BO,Aldrich FD,Utter GM,DeBroy JA,Schimke RD

更新日期：1992-04-30 00:00:00