[Effectiveness of nephroprotection by the selection of contrast media used during vascular interventions in patients with chronic renal failure?].

Abstract:

BACKGROUND:The increasing number of endovascular procedures made aware of a kidney disease induced by contrast media (CM). Contrast-induced nephropathy (= CIN) can develop in 0.6-44 % of the treated patients by angiography and / or endovascular intervention. The incidence in high-risk patients ranges from 50 to 70 %. In most cases CIN is inconspicuous and reversible. But pre-existing chronic kidney disease, diabetes mellitus, age and variable different risk factors (e. g., PAOD) can induce irreversible renal impairment. The purpose of the presented trial is to investigate incidence, predictors, and out-come of CIN in chronic renal failure patients using two different CM; one non-ionic isoosmolar -iodixanol and the other non-ionic low-osmolar iopromide. METHODS:To evaluate the incidence of CIN after endovascular diagnostics and intervention two collectives of 100  patients with chronic renal insufficiency were treated with different contrast media (CM). Inclusion followed prospectively in two collectives. One collective received iopromide (Ultravist™, Bayer Health Care, Lever-kusen, Germany), and the second hundred patients received iodixanol (Visipaque™, Nycomed Amersham, Princeton, New Jersey). Demographics, comorbidities, procedure-related data were completed by serum creatinine levels and GFR (= glomerular filtration rate). Inclusion criteria were a serum creatinine level ≥ 1.5 mg% and a GFR ≤ 60 mL / min. Those parameters were measured twice pre-interventionally, and one time 48-72  hours after the endovascular procedure. RESULTS:Collectives were homogenous and comparable concerning pre-existing risk factors, age and gender. Renal function stayed at a constant level and was independent of contrast medium selection, repectively. Average creatinine levels ranged around 1.77 mg% ± 0.75  standard deviation (SD) pre-interventionally; postinterventional measurement exposed a creatinine level of 1.74 mg% ± 0.74 SD as mean of both collectives. GFR (preinterventional 39.64 mL / min ± 12.48 SD) increased non-significantly to 45.48 mL / min ± 16.82 SD. Pre-existing chronic kidney disease had no effect on renal function parameters; no other risk factors could be evaluated. CONCLUSION:According to cost-effectiveness a low-osmolar monomeric contrast medium (LOCM) is a sufficient selection, under careful renal function control.

journal_name

Zentralbl Chir

authors

Schönefeld E,Höwler S,Osada N,Torsello G

doi

10.1055/s-0031-1283759

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

426-30

issue

5

eissn

0044-409X

issn

1438-9592

journal_volume

136

pub_type

杂志文章
  • [Locking plate osteosynthesis for fractures of the proximal humerus].

    abstract:BACKGROUND:Beside non-operative treatment the therapeutic options for proximal fractures of the humerus range from closed reduction and transcutaneous K-wiring to total joint replacement. While the first is regarded as minimally invasive the latter is a rather complex intervention. Plating has been disregarded as combi...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:10.1055/s-2003-37368

    authors: Lungershausen W,Bach O,Lorenz CO

    更新日期:2003-01-01 00:00:00

  • [Selection of the treatment method in rectal cancer].

    abstract::From 1956 to 1982, 4126 patients suffering from rectal cancer underwent surgery, 3229 of them had radical operations. The total postoperative mortality rate came up to 7.1% (n = 295) in the radical operated group it was 6.6% (n = 214). Between 1956 to 1982 continence preserving surgical procedures were constantly on t...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Fedorov VD

    更新日期:1985-01-01 00:00:00

  • [The embolisation of venous malformations].

    abstract:BACKGROUND:The treatment of congenital, vascular malformations is a challenge for physicians and patients. Although different therapeutic options have been described to date, their individual relevance has still to be defined. Â METHODS: We performed a retrospective study of 61 patients with a venous malformation (VM, ...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0030-1262751

    authors: Barbera L,Fiedler HW,Krauss M

    更新日期:2012-10-01 00:00:00

  • [Intraperitoneal infections and immunosuppression (author's transl)].

    abstract::The growing number of patients showing a restricted immune defence, also causes the surgeon to be faced with big problems; particularly in the case of intraperitoneal infections. In case of peritonitis the organism may dispose of various opportunities of immune defence involving the local limitation by adhesions, phag...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Hau T,Lippert H

    更新日期:1982-01-01 00:00:00

  • [Prospective multicenter trial of gastric cancer surgery--a contribution to clinical research on quality control].

    abstract::By the mean of a prospective multicenter observational study (East German Gastric Cancer Study - EGGCS), 1 139 consecutive patients with gastric cancer were enrolled in 80 East German surgical departments from January 1 to December 31, 2002. Out of them, 1,031 (90.5%) underwent surgical intervention. The resection rat...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章,多中心研究

    doi:10.1055/s-2005-836491

    authors: Meyer L,Steinert R,Nowak L,Gellert K,Ludwig K,Saeger D,Gastinger I,Lippert H

    更新日期:2005-04-01 00:00:00

  • [Early death of the severly injured patient--A retrospective analysis].

    abstract::With 44.9 % trauma is the main cause of death in men under 40 years. From September 3(rd) 1997 to June 30(th) 1998 174 patients with severe injuries or polytrauma were treated in our hospital. The mean ISS was 29 (18-75). 15 (8.75 %) patients died within the first 24 hours. The mean age was 34.5 (2-85) years. The mean...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:10.1055/s-2001-19658

    authors: Matthes G,Seifert J,Ostermann PA,Würfel S,Ekkernkamp A,Wich M

    更新日期:2001-12-01 00:00:00

  • [Parenteral or enteral hyperalimentation in the treatment of enterocutaneous fistulas?].

    abstract::Occurrence of postoperative wound dehiscence with fistulae in stomach and small intestine is considered to be a severe surgical complication. The question has been raised, if the problem should be therapeutically tackled by means of surgery or medication in the context of intensive care. Retrospective and prospective ...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Wolf G,Steindorfer P,Pierer G

    更新日期:1988-01-01 00:00:00

  • [Usage of marginal organs for liver transplantation: a way around the critical organ shortage?].

    abstract::The transplantation of marginal organs or those meeting the so-called extended donor criteria (EDC) is today a significant option to alleviate the low availability or organs and to increase the number of transplantation which in turn is -accompanied by a lower mortality among wait-ing-list patients. However such an ex...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0028-1098880

    authors: Pratschke S,Loehe F,Graeb C,Jauch KW,Angele MK

    更新日期:2009-04-01 00:00:00

  • [The syndrome of the fifth day (author's transl)].

    abstract::After operation of uncomplicated forms of appendicitis in children postoperative complications characterised by sudden vehement stomach-ache, quickly increasing tension of the abdominal wall, rise of temperature, pulse and white blood cells as well as vomitus, mostly on the fifth post-operative day could be observed. ...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Weber B

    更新日期:1978-01-01 00:00:00

  • [Fetoscopic surgery as prenatal intervention for isolated congenital diaphragmatic hernia].

    abstract::Congenital diaphragmatic hernia (CDH) occurs sporadically with an incidence of 1:2,500 live births. Despite the progress in neonatal intensive care, CDH remains associated with a mortality of at least 30 % in isolated cases. The in essence surgically correctable defect of the diaphragm enables the prenatal herniation ...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0029-1224604

    authors: Mayer S,Kluth D,Till H,Deprest J

    更新日期:2009-12-01 00:00:00

  • [Malignant melanomas of fingers and toes (author's transl)].

    abstract::From 1968 to 1978 more than 500 patients suffering from histologically verified malignant melanoma were seen. Only in 12 cases (appr. 2%) the tumour was situated on the tip of the fingers and toes. In such cases nowadays amputation and exarticulation of the whole extremity is no longer practiced. It is sufficient only...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Krauss J,Gstöttner R,Reiss CJ,Hassler N,Erbe H,Müller R

    更新日期:1979-01-01 00:00:00

  • [Osteosynthesis of ipsilateral hip and femoral shaft fractures with the PFN-long].

    abstract:AIM:The paper retrospectively evaluates a set of patients with ipsilateral fractures of the proximal femur and shaft treated with PFN-long. MATERIAL:19 patients (14 males and 5 females), aged 48 in average, were treated from 1998-2003. The fractures included 2 types: combined intraarticular femoral neck and shaft frac...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:10.1055/s-2005-836368

    authors: Pavelka T,Lihart M,Matejka J,Vyskocil V

    更新日期:2005-04-01 00:00:00

  • [The Risks of Perioperative Addiction to Benzodiazepines in the Elderly: What the Surgeon Needs to Know].

    abstract:BACKGROUND:In Germany, more than one million people use benzodiazepines on a regular basis. The majority of them is older than 60 years and take low-dose benzodiazepines for sleep disorders. This does not necessarily induce tolerance, but may result in problems such as falling, seizures or delirium if benzodiazepines a...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0041-107198

    authors: Brinkers M,Pfau G,Schilling T,Meyer F

    更新日期:2016-02-01 00:00:00

  • [The influence of taurolidine on physiological and pathological blood coagulation and implications for its use].

    abstract::Taurolidine is an anti-infective agent with an unusually broad spectrum of effectivity against gram-positive and gram-negative bacteria, anaerobic organisms, and fungi. The effective principle is explained by the decomposition of the substance and the transfer of methylol groups to specific molecular structures of the...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Reinmüller J

    更新日期:1999-01-01 00:00:00

  • [Rahel Hirsch (1870-1953). The first Prussian woman medical professor].

    abstract::Dr. Rahel Hirsch was only the second woman to attain a professional medical position at the Charité Hospital in Berlin. For more than 16 years, she worked in Clinic II Internal Medicine. In 1906, she discovered that solid particles are able to pass from the veins and arteries into urine (Hirsch-Effect). The results of...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Müller-Schubert A,Kox W

    更新日期:1999-01-01 00:00:00

  • [Diagnosis of liver tumors--what is necessary for therapy planning?].

    abstract::For the surgical treatment of liver tumors, two initial steps are necessary: functional operability must be proven and oncological and local inoperability must be ruled out. The diagnostic process consists of a series of steps, beginning with non-invasive procedures such as laboratory findings and sonography, continui...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章,评审

    doi:

    authors: Hinterthaner M,Müller A,Ulrich A,Decker P,Hirner A,Layer G

    更新日期:1998-01-01 00:00:00

  • [The value of blood transfusion in tumor surgery. Experiences from randomized trials].

    abstract::Since the first publication by Tartter in 1982 [3] multiple studies were performed concerning the association between blood transfusion and outcome in surgical oncology. The hypothesis was that blood transfusion-associated immunosuppression influences postoperative infection rates and long-term prognosis. Due to the f...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2000-10045

    authors: Heiss MM

    更新日期:2000-01-01 00:00:00

  • [Laparoscopic therapy of colorectal cancer--wishful thinking or realism?].

    abstract::The laparoscopic resection of the colon and rectum is established for surgery of benign diseases. The main advantages compared to the open-conventional operation technique are reduced postoperative pain, reduced negative influences on pulmonary and gastrointestinal functions as well as a shorter reconvalescence. Minim...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:10.1055/s-2003-44844

    authors: Keller R,Roblick UJ,Schwandner O,Bruch HP

    更新日期:2003-12-01 00:00:00

  • [Anti-infectious regime and bacteriological status].

    abstract::The functioning of our anti-infectious regimen now working over a period of 7 years with 4 checks per year has been controlled. The wound infection rate came up to a percentage of 1.55. Blunders concerning chemical disinfection especially could be detected in spite of check-ups made every 3 months. ...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Siggelkow G

    更新日期:1982-01-01 00:00:00

  • [Internal drainage surgery in pancreatic pseudocysts].

    abstract::60 pancreatic pseudocysts are reported. 29 cystojejunostomies, 22 cystogastrostomies, 2 cystoduodenostomies and 7 external drainages were performed. Most favourable results could be recorded by cystojejunostomy. The total operative mortality was 8.3%, after cystojejunostomie 3.4%. Most dangerous complications were hae...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Schröder H,Friedel R,Pfefferkorn S

    更新日期:1989-01-01 00:00:00

  • [Forgotten Dresden Surgeons (I)].

    abstract::This article describes problems some surgeons of Dresden were confronted with in the time between 1750 and 1850. These surgeons present the transition of the 'Age of Enlightment' and the period of sciences. Special achievements are mentioned: Hedenus as the founder of the modern surgery in Dresden and as a pioneer in ...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 历史文章,杂志文章

    doi:

    authors: Klimpel V

    更新日期:1996-01-01 00:00:00

  • [Postoperative abdominal complications after thoracic surgery (author's transl)].

    abstract::Between 1964 to 1974 2940 patients underwent chest operations. 15 cases with abdominal complications among them are analyzed. 10 patients had bleeding gastric or duodenal ulcers with a high mortality rate. Postoperative gastric distention was one of the most important causes. A gastric tube should be introduced whenev...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Franz WD

    更新日期:1977-01-01 00:00:00

  • [Changes in therapeutic principles in fractures of the extremities with severe soft tissue injuries exemplified by tibial fracture].

    abstract::Functional results after open fractures have been improved during the last decades. Especially the rates of amputation and chronic osteitis after open tibial fractures have been reduced from 30% to less than 5%. The initial management of this type of fracture includes reconstruction of the perfusion of the involved ve...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章,评审

    doi:

    authors: Dávid A,Ostermann PA,Möllenhoff G,Hebebrand D,Muhr G

    更新日期:1997-01-01 00:00:00

  • [The Whipple partial duodenopancreatectomy--its value in the treatment of chronic pancreatitis].

    abstract::The surgical treatment of chronic pancreatitis is indicated only in the complicated disease. The aim is mainly the treatment of pain, of mechanical obstacles and to exclude suspicion of cancer. Between October 1972 and January 1993 713 patients with chronic pancreatitis were treated at the Surgical University Hospital...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Saeger HD,Schwall G,Trede M

    更新日期:1995-01-01 00:00:00

  • [Change in concept--from vascular centre to interdisciplinary organ-oriented clinic for vascular medicine].

    abstract::Demographic developments have led to an exponential increase of cardiovascular illness. Additionally, the technical development of conservative and invasive treatment modalities has added to an increase of differentiated therapy. The development of vascular centres led to optimised processes in diagnostic and therapy ...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0031-1271602

    authors: Diener H,Larena-Avellaneda A,Koelbel T,Tato F,Debus S

    更新日期:2013-10-01 00:00:00

  • [Transplantation and hepatic, pancreatic, and biliary (HPB) surgery fellowship--a pilot project for a structured training in Germany].

    abstract::Currently, there is no structured training plan to become a transplant surgeon in Germany. Similar to the Anglo-Saxonian educational system we have implemented a 3-year fellowship in transplant and hepatic-, pancreatic-, biliary (HPB) surgery. The educational curriculum is based on the guidelines of the European Board...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0032-1328738

    authors: Guba M,Andrassy J,Stangl M,Jauch KW

    更新日期:2014-06-01 00:00:00

  • [Surgery of malignant hepatoma of the cirrhotic liver].

    abstract::The surgical approach to malignant hepatoma in cirrhotic liver has continued to be an unresolved problem. Early diagnosis, differentiated indication, and surgical techniques need further improvement, before adjuvant therapy can be discussed. All surgeons are called upon to verify experience of the past and to integrat...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章,评审

    doi:

    authors: Esser G

    更新日期:1989-01-01 00:00:00

  • [Treatment of unstable thoracolumbar spinal injuries--determination of its present status and a preliminary report on transpedicular stabilization].

    abstract::Follow-up checks were made on 19 patients with instabile injuries of the thoracolumbar spine. Poor late results were recorded from eleven of them who had undergone conservative or inadequate surgical treatment. Axial malposition of severe clinical disorders were among the findings. Transpedicular osteosynthesis of ins...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Wendsche P,Michek J,Unger C

    更新日期:1988-01-01 00:00:00

  • [Aspergillosis in a thoracic surgery patient sample. 20 years' results].

    abstract::40 patients underwent surgery for aspergilloma at the authors' ward of thoracic surgery. Pulmonary defects or cavities were recorded from 95 per cent of them (13 cases of bronchiectasis, eight with tuberculous caverns, and six cysts). Serological methods, 100 per cent in accuracy, were superior to all other diagnostic...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Plate H,Demischew M

    更新日期:1987-01-01 00:00:00

  • [Post-traumatic hemobilia].

    abstract::Diagnosing posttraumatic haemobilia is difficult since the symptoms are neither specific nor early or easy to detect. At present the mortality rate comes up to 20%. Clinical signs and diagnostic procedures are described in detail. Selective ligation of the liver arteries or partial resection of the involved lobes of t...

    journal_title:Zentralblatt fur Chirurgie

    pub_type: 杂志文章

    doi:

    authors: Fleischer GM,Reppin G,Freitag J

    更新日期:1983-01-01 00:00:00