Cost-effectiveness of the introduction of two-dose bi-valent (Cervarix) and quadrivalent (Gardasil) HPV vaccination for adolescent girls in Bangladesh.

abstract：:In HIV vaccine trials, the collection and analysis of participant behavior data associated with risk of acquiring HIV-infection is important for a number of reasons. Although the rationale for behavioral risk assessment in HIV vaccine clinical trials is clear, consistent collection of behavioral data over time and acr...

journal_title：Vaccine

authors： Andrasik MP,Karuna ST,Nebergall M,Koblin BA,Kublin JG,NIAID HIV Vaccine Trials Network.

更新日期：2013-09-13 00:00:00

abstract：:We tested whether pilus proteins of rabbit diarrhoeagenic Escherichia coli (RDEC-1), incorporated into biodegradable microspheres, could function as safe and effective oral immunogens in the rabbit diarrhoea model. The RDEC-1 adhesin, AF/R1, incorporated into poly(D,L-lactide-co-glycolide) microspheres, was administer...

journal_title：Vaccine

authors： McQueen CE,Boedeker EC,Reid R,Jarboe D,Wolf M,Le M,Brown WR

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Streptococcus pyogenes (group A Streptococcus, Strep A) is a widespread pathogen that continues to pose a significant threat to human health. The development of a Strep A vaccine remains an unmet global health need. One of the major vaccine strategies is the use of M protein, which is a primary virulence det...

journal_title：Vaccine

authors： Pastural É,McNeil SA,MacKinnon-Cameron D,Ye L,Langley JM,Stewart R,Martin LH,Hurley GJ,Salehi S,Penfound TA,Halperin S,Dale JB

更新日期：2020-02-05 00:00:00

abstract：:Transmission-blocking vaccines against malaria parasites target molecules expressed by sexual stage parasites to elicit antibodies that prevent the infection of the mosquito vector. Pvs25 and Pvs28, expressed on the surface of ookinetes, are potential candidates for such a vaccine and induce antibodies that block the ...

journal_title：Vaccine

authors： Hisaeda H,Collins WE,Saul A,Stowers AW

更新日期：2001-12-12 00:00:00

abstract：:It has been hypothesized that antibody induced by Plasmodium falciparum circumsporozoite protein vaccine would be effective against endemic human malaria. In a malaria endemic region of Kenya, 76 volunteers, in 38 pairs sleeping adjacently, were immunized with subunit circumsporozoite protein Asn-Ala-Asn-Pro tetrapept...

journal_title：Vaccine

authors： Sherwood JA,Copeland RS,Taylor KA,Abok K,Oloo AJ,Were JB,Strickland GT,Gordon DM,Ballou WR,Bales JD Jr,Wirtz RA,Wittes J,Gross M,Que JU,Cryz SJ,Oster CN,Roberts CR,Sadoff JC

更新日期：1996-06-01 00:00:00

abstract：:Rotavirus vaccine was introduced in El Salvador in 2006 and is recommended to be given concomitantly with DTP-HepB-Haemophilus influenzae type b (pentavalent) vaccine at ages 2 months (upper age limit 15 weeks) and 4 months (upper age limit 8 months) of age. However, rotavirus vaccination coverage continues to lag beh...

journal_title：Vaccine

authors： Suarez-Castaneda E,Burnett E,Elas M,Baltrons R,Pezzoli L,Flannery B,Kleinbaum D,de Oliveira LH,Danovaro-Holliday MC

更新日期：2015-11-27 00:00:00

abstract：OBJECTIVE:To compare timely birth dose (TBD) coverage of hepatitis B vaccine and socio-economic inequality distribution of TBD coverage between 2011 and 2016 in rural areas of western China. METHODS:In western China, using multi-stage probability proportion to size sampling, 2633 and 1929 children aged 0-35 months wit...

journal_title：Vaccine

authors： Liu X,Yang C,Zhong Q,Song Q,Huang X,Yang Y,Huang Y,Wang Y,Zhou H

更新日期：2018-06-22 00:00:00

abstract：:The toxicity of Clostridium difficile large clostridial toxin B (TcdB) can be reduced by many orders of magnitude by a combination of targeted point mutations. However, a TcdB mutant with five point mutations (referred to herein as mTcdB) still has residual toxicity that can be detected in cell-based assays and in-viv...

journal_title：Vaccine

authors： Wang B,Wang S,Rustandi RR,Wang F,Mensch CD,Hong L,Kristopeit A,Secore S,Dornadula G,Kanavage A,Heinrichs JH,Mach H,Blue JT,Thiriot DS

更新日期：2015-01-01 00:00:00

abstract：:It is known that the immunogenicity and efficacy of conventional inactivated influenza vaccines (IIVs) are not completely satisfactory in children. The aim of this prospective, randomised, single-blind study was to compare the immune response to, and the effectiveness and safety of, an IIV (Fluarix, GlaxoSmithKline Bi...

journal_title：Vaccine

authors： Esposito S,Marchisio P,Prada E,Daleno C,Porretti L,Carsetti R,Bosco A,Ierardi V,Scala A,Principi N

更新日期：2014-05-07 00:00:00

abstract：INTRODUCTION:Hepatitis B is a major preventable cause of morbidity and mortality from chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. We aimed to evaluate the performance and outcomes of the Korean Perinatal Hepatitis B Prevention Programme (PHBPP) and to investigate the impact of the current post-exp...

journal_title：Vaccine

authors： Yang TU,Jung CW,Kim D,Park HA,Jee Y

更新日期：2020-07-22 00:00:00

abstract：:A major challenge for poultry vaccination is the design of vaccines that protect against multiple pathogens via a single protective dose delivered through mass vaccination methods. In this investigation, we examined herpesvirus of turkeys (HVT) as a vaccine vector for delivery of haemagglutinin (HA) antigen of highly ...

journal_title：Vaccine

authors： Li Y,Reddy K,Reid SM,Cox WJ,Brown IH,Britton P,Nair V,Iqbal M

更新日期：2011-10-26 00:00:00

abstract：:In order to evaluate in humans the safety and immunogenicity of a Pseudomonas aeruginosa vaccine composed of outer membrane proteins (OMPs), CFC-101, we carried out a phase I/IIa clinical trial in healthy male volunteers. Groups of six volunteers were immunized either subcutaneously (s.c.) or intramuscularly (i.m.) wi...

journal_title：Vaccine

authors： Jang IJ,Kim IS,Park WJ,Yoo KS,Yim DS,Kim HK,Shin SG,Chang WH,Lee NG,Jung SB,Ahn DH,Cho YJ,Ahn BY,Lee Y,Kim YG,Nam SW,Kim HS

更新日期：1999-01-01 00:00:00

abstract：:Recently, it was discovered that sialic acid residues on group B streptococcal (GBS) capsular polysaccharides (CPS) are O-acetylated. Since GBS vaccine development has focused on de-O-acetylated CPS, it became germane to investigate the influence of de-O-acetylated GBS vaccine formulations on functional activity of se...

journal_title：Vaccine

authors： Pannaraj PS,Edwards MS,Ewing KT,Lewis AL,Rench MA,Baker CJ

更新日期：2009-07-16 00:00:00

abstract：:Swine influenza virus (SIV) is not only an important respiratory pathogen in pigs but also a potent threat to human health. Although immunization with recombinant poxviruses expressing protective antigens as vaccines has been widely used for against many infectious diseases, development of recombinant swinepox virus (...

journal_title：Vaccine

authors： Xu J,Huang D,Liu S,Lin H,Zhu H,Liu B,Lu C

更新日期：2012-04-26 00:00:00

abstract：BACKGROUND:Vaccination uptake at the individual level can be assessed in a variety of ways, including traditional measures of being up-to-date (UTD), measures of UTD that consider dose timing, like age-appropriate vaccination, and risk reduction from individual doses. This analysis compared methods of operationalizing ...

journal_title：Vaccine

authors： Goldstein ND,Newbern EC,Evans AA,Drezner K,Welles SL

更新日期：2015-07-31 00:00:00

abstract：:We evaluated a modified HBV regimen in a cohort of HIV-infected subjects in Rio de Janeiro, Brazil. HIV-infected subjects with no serologic evidences of previous hepatitis B infection were immunized with 4 doses (40 microg each) of recombinant hepatitis B vaccine given at 0, 1, 2 and 6 months. Blood samples were colle...

journal_title：Vaccine

authors： Potsch DV,Oliveira ML,Ginuíno C,Miguel JC,Oliveira SA,Silva EF,Moreira RB,Cruz GV,Oliveira AL,Camacho LA,Barroso PF

更新日期：2010-02-10 00:00:00

abstract：:Adult patients with mucosal leishmaniasis (ML) were enrolled in a randomized, double-blind, placebo-controlled, dose-escalating clinical trial and were randomly assigned to receive three injections of either the LEISH-F1+MPL-SE vaccine (consisting of 5, 10, or 20 μg recombinant Leishmania polyprotein LEISH-F1 antigen+...

journal_title：Vaccine

authors： Llanos-Cuentas A,Calderón W,Cruz M,Ashman JA,Alves FP,Coler RN,Bogatzki LY,Bertholet S,Laughlin EM,Kahn SJ,Beckmann AM,Cowgill KD,Reed SG,Piazza FM

更新日期：2010-10-28 00:00:00

abstract：:Chlamydia trachomatis causes respiratory and sexually transmitted infections. Here, we tested a vaccine formulated with the recombinant major outer membrane protein from C. trachomatis mouse pneumonitis (CT-MoPn) for its ability to protect mice against an intranasal (i.n.) challenge. The adjuvants CpG and Montanide we...

journal_title：Vaccine

authors： Ralli-Jain P,Tifrea D,Cheng C,Pal S,de la Maza LM

更新日期：2010-11-10 00:00:00

abstract：INTRODUCTION:One of the goals of the Global Measles and Rubella Strategic Plan is the reduction in global measles mortality, with high measles vaccination coverage as one of its core components. While measles mortality has been reduced more than 79%, the disease remains a major cause of childhood vaccine preventable di...

journal_title：Vaccine

authors： Doshi RH,Eckhoff P,Cheng A,Hoff NA,Mukadi P,Shidi C,Gerber S,Wemakoy EO,Muyembe-Tafum JJ,Kominski GF,Rimoin AW

更新日期：2017-10-27 00:00:00

abstract：:Recombinant replication-defective human adenovirus type 5 (Ad5) vaccines containing capsid-coding regions from foot-and-mouth disease virus (FMDV) have been demonstrated to induce effective immune responses and provide homologous protective immunity against FMDV in cattle. However, basic mechanisms of Ad5-FMDV vaccine...

journal_title：Vaccine

authors： Montiel N,Smoliga G,Arzt J

更新日期：2012-02-21 00:00:00

abstract：:The continuously increasing demand for potent and safe vaccines and the intensifying economic pressure on health care systems underlines the need for further optimization of vaccine manufacturing. Here, we focus on downstream processing of human influenza vaccines, investigating the purification of serum-free cell cul...

journal_title：Vaccine

authors： Fischer LM,Wolff MW,Reichl U

更新日期：2018-05-24 00:00:00

abstract：:To evaluate the safety and immunogenicity of a diphtheria, tetanus, acellular pertussis and Haemophilus infuenzae Type b (DTaP/Hib) combination vaccine first developed by a Chinese manufacturer, a randomized, two-stage, parallel controlled, single center clinical trial was conducted in Dafeng, Jiangsu Province of Chin...

journal_title：Vaccine

authors： Li G,Zhang H,Zhou W,Ye Q,Li F,Wang H,Hou Q,Xu Y,Ma X,Tan Y,Wang L,Li Y,Li H,Meng F,Liang Q,Liu A,Qin C,Wei W,Liu J,Ruan C,Tao W,Zhang S,Zheng H,Zhu F

更新日期：2010-06-07 00:00:00

abstract：:To assess the reactogenicity and immunogenicity of the Biken acellular pertussis vaccine (Pa) following administration of a single vaccine dose to young adults with or without a history of prior pertussis immunization, 104 healthy, male and female adults without primary pertussis immunization were enrolled in Mainz (f...

journal_title：Vaccine

authors： Schmitt HJ,Mohnike K,Zepp F,Herden P,Hosbach P

更新日期：2000-10-15 00:00:00

abstract：:Understanding the mechanisms of generation and maintenance of immunological memory is crucial for rational vaccine design. A hypothesis known as relay hypothesis was earlier proposed which explains the maintenance of immunological memory through interaction of idiotypic and anti-idiotypic lymphocytes. In the present s...

journal_title：Vaccine

authors： Vani J,Nayak R,Shaila MS

更新日期：2007-06-21 00:00:00

abstract：:Respiratory syncytial virus (RSV) infection is the single most important cause of serious acute respiratory illness in children <1 year of age worldwide, and is associated with life-threatening pneumonia or bronchiolitis in the elderly. Current vaccine strategies include live, attenuated virus, subunit and DNA vaccine...

journal_title：Vaccine

authors： Harcourt JL,Brown MP,Anderson LJ,Tripp RA

更新日期：2003-06-20 00:00:00

abstract：:Myxoma virus, a member of the Poxviridae family (genus Leporipoxvirus) is the agent responsible for myxomatosis in the European rabbit. Recombinant myxoma viruses expressing the capsid gene of an F9 strain of feline calicivirus (FCV) were constructed from an apathogenic, laboratory attenuated, isolate of myxoma virus....

journal_title：Vaccine

authors： McCabe VJ,Tarpey I,Spibey N

更新日期：2002-06-07 00:00:00

abstract：:A cost-effectiveness analysis of the introduction of acellular pertussis booster doses at either 4 or 15 years of age was performed. A transmission dynamic model was used to predict the level of indirect protection in those too young to be vaccinated. Multivariate sensitivity analyses were performed. In England and Wa...

journal_title：Vaccine

authors： Edmunds WJ,Brisson M,Melegaro A,Gay NJ

更新日期：2002-01-31 00:00:00

abstract：:Intranasal (i.n.) immunization is an effective regimen for the prophylaxis of respiratory diseases in early life. The aim of this study was to assess the need for nasal-associated lymphoid tissue (NALT) and cervical lymph nodes (CLN) in induction of protective immunity following mucosal vaccination of infant mice. We ...

journal_title：Vaccine

authors： Sabirov A,Metzger DW

更新日期：2008-03-17 00:00:00

abstract：:Peripheral blood mononuclear cells were taken from subjects before and after oral immunization with cholera toxin B-subunit. Cells obtained from naive volunteers before immunization did not proliferate in vitro to B-subunit. Oral immunization induced a proliferative response in all volunteers with a peak stimulation i...

journal_title：Vaccine

authors： Lewis DJ,Castello-Branco LR,Novotny P,Dougan G,Poulton TA,Griffin GE

更新日期：1993-01-01 00:00:00

abstract：:DNA immunization is an attractive form of vaccination, which has shown promising results only in small animal models. There is a need to develop efficient gene delivery systems. We previously demonstrated that oxidized (OM) and reduced mannan (RM) complexed to ovalbumin DNA via poly-l-lysine (PLL), were able to genera...

journal_title：Vaccine

authors： Tang CK,Sheng KC,Pouniotis D,Esparon S,Son HY,Kim CW,Pietersz GA,Apostolopoulos V

更新日期：2008-07-23 00:00:00