Abstract:
:A review of the selective posterior rhizotomy procedure for reduction of spasticity in cerebral palsy is presented. The history of the procedure, selection of patients, operative technique, and results are described. The neurophysiologic basis for spasticity is considered, as well as the role of spasticity in the complex motor disorder of cerebral palsy. Cerebral palsy is a multifaceted disorder of which spasticity is only one aspect. Reduction of spasticity can be effectively achieved using the current technique of selective posterior rhizotomy, but careful patient selection and establishment of realistic goals are vital to successful outcome. Postoperative physical and occupational therapy are felt to be essential for regaining strength and improving motor function following the rhizotomy procedure. Further study in the areas of spasticity, cerebral palsy, and the effects of rhizotomy is expected to advance our treatment of spastic children.
journal_name
J Child Neuroljournal_title
Journal of child neurologyauthors
Peacock WJ,Staudt LAdoi
10.1177/088307389000500303subject
Has Abstractpub_date
1990-07-01 00:00:00pages
179-85issue
3eissn
0883-0738issn
1708-8283journal_volume
5pub_type
杂志文章,评审abstract::We present 12 cases of males with myalgia and cramps and a normal muscle strength examination. All the patients had muscle dystrophin values consistent with Becker muscular dystrophy. Five of the patients had a normal electromyogram, and five had normal light microscopic muscle biopsy results. Of particular note, four...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389601100105
更新日期:1996-01-01 00:00:00
abstract::We report a case of a neonate with sectional narrowing of the spinal cord on the level of T12 to L2 and a deformed vertebral body on a different level, L4. In previously described cases of sectional spinal dysgenesis, the vertebral and spinal cord malformations are usually found on the same level. Our case may represe...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380101600819
更新日期:2001-08-01 00:00:00
abstract::Neonatal alloimmune thrombocytopenia results from platelet-antigen incompatibility between mother and fetus, leading to antibody-mediated destruction of fetal platelets. With a prevalence of 1 in 1000 births, approximately 4000 infants born in the United States each year develop neonatal alloimmune thrombocytopenia. T...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738010160111001
更新日期:2001-11-01 00:00:00
abstract::The objective of this study was to determine the role of cerebral nitric oxide and its powerful oxidant peroxynitrite following mild birth asphyxia. The cerebrospinal fluid levels of nitric oxide and 3-nitrotyrosine as a marker for peroxynitrite are measured in neonates with mild hypoxic-ischemic encephalopathy. Based...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738020170111101
更新日期:2002-11-01 00:00:00
abstract::Adolescence is an important period, marked by significant changes in biological and psychosocial domains. Epilepsy is a chronic neurologic disorder associated with social stigma and prejudice. The etiology of depression in epilepsy appears to be a complex interplay between psychosocial and neurobiologic factors. This ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073820954060
更新日期:2021-02-01 00:00:00
abstract::Seven school-aged children treated for temporal lobe astrocytomas with surgical resection and irradiation were prospectively tested to evaluate their intellectual, academic, personality, and neurologic status after therapy. At their most recent follow-up examination, neuropsychologic functioning was adequate in only t...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307388800300111
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVES:The objectives were to investigate the relationship between ketogenic diet therapy and neutropenia in children with epilepsy. METHODS:A retrospective chart review of children who initiated ketogenic diet at the Hospital for Sick Children between January 1, 2000, and May 1, 2018 was performed. Factors associ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073820984067
更新日期:2021-01-04 00:00:00
abstract:BACKGROUND:Rufinamide, a triazole derivative, is a new-generation antiseizure medication with a novel mechanism of action. We evaluated the efficacy and safety of rufinamide treatment in children with epilepsy younger than 4 years at our center. METHODS:In this retrospective study, we included children younger than 4 ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073820967159
更新日期:2021-03-01 00:00:00
abstract::Metabolic disorders constitute an important cause of neurologic disease, including infantile epilepsy. The inability to characterize seizures and epilepsy syndromes precisely in infants impedes the recognition of features suggestive of specific underlying metabolic and neurodegenerative etiologies. Classification syst...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:
更新日期:2002-12-01 00:00:00
abstract::Freely available software, derived from the past 2 decades of neuroimaging research, is significantly more flexible for research purposes than presently available clinical tools. Here, we describe and demonstrate the utility of rapidly deployable analysis software to facilitate trainee-driven translational neuroimagin...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073816668113
更新日期:2017-01-01 00:00:00
abstract::A behavior questionnaire was used retrospectively in 21 manic-depressive children to quantitate manic-depressive behaviors before and after treatment with lithium carbonate. The study children were matched with 21 control children for age, race, sex, and socioeconomic status. The study children had significantly more ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307388600100409
更新日期:1986-10-01 00:00:00
abstract::Schilder's myelinoclastic diffuse sclerosis is a rare sporadic demyelinating disease that usually affects children between 5 and 14 years old. The disease often mimics intracranial neoplasm or abscess. We report a 9-year-old girl with Schilder's disease who presented with left hemiparesis. Cranial computed tomography ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738030180011301
更新日期:2003-01-01 00:00:00
abstract::Visual electrophysiological techniques represent excellent means for assessing retinal, optic pathways and visual cortex function. Electroretinograms, visual evoked potentials, and clinical records of 17 patients with mucopolysaccharidosis registered in the neurophysiological database of our institution were reviewed ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073812453322
更新日期:2013-10-01 00:00:00
abstract::Multiple risk factors contribute to cognitive impairment in children with β-thalassemia major. For a more refined understanding of this issue, we attempted to evaluate cognitive function in β-thalassemia major patients and identify the relationship between possible cognitive dysfunction and the following: demography, ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073814550827
更新日期:2015-03-01 00:00:00
abstract::Children and adolescents with the Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) diagnosis of attention-deficit hyperactivity disorder (ADHD) can have comorbid conditions such as conduct disorder, oppositional defiant disorder, and obsessive-compulsive disorder (comorbid type). The purpose of our st...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738040190020201
更新日期:2004-02-01 00:00:00
abstract::A variety of endocrine and metabolic defects, including hypothalamopituitary hypofunction and diabetes mellitus, has been reported in association with mitochondrial disorders. We describe two sisters affected by mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes (MELAS) syndrome in whom DNA anal...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380001501108
更新日期:2000-11-01 00:00:00
abstract::To determine the plasma baclofen concentrations of children undergoing continuous intrathecal baclofen infusion for treatment of cerebral spasticity, we assayed plasma samples from six children, 8 to 18 years of age, who were receiving intrathecal baclofen at constant rates of 77 to 400 micrograms/day. Plasma levels w...
journal_title:Journal of child neurology
pub_type: 临床试验,杂志文章
doi:10.1177/088307389901400611
更新日期:1999-06-01 00:00:00
abstract::Direct perfusion of specific regions of the central nervous system by convection-enhanced delivery is becoming more widely used for the delivery of compounds in the research and treatment of various neural disorders. In contrast to other currently available central nervous system delivery techniques, convection-enhanc...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/0883073808321064
更新日期:2008-10-01 00:00:00
abstract::Actinopathies are defined by missense mutations in the ACTA1 gene coding for sarcomeric actin, of which some 70 families have, so far, been identified. Often, but not always, muscle fibers carry large patches of actin filaments. Many such patients also have nemaline myopathy, qualifying actinopathies as a subgroup of ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738040190021201
更新日期:2004-02-01 00:00:00
abstract::Attention Deficit Hyperactivity Disorder (ADHD) is associated with altered cerebellar volume and cerebellum is associated with cognitive performance. However there are mixed results regarding the cerebellar volume in young patients with ADHD. To clarify the size and direction of this effect, we conducted the analysis ...
journal_title:Journal of child neurology
pub_type: 杂志文章,多中心研究
doi:10.1177/0883073816678550
更新日期:2017-02-01 00:00:00
abstract::The ketogenic diet has traditionally been considered an anticonvulsant therapy of last resort, despite excellent efficacy and limited side effects. We hypothesized that the ketogenic diet would have similar results in patients with new-onset epilepsy. A retrospective study was conducted of patients started on the keto...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738050200010501
更新日期:2005-01-01 00:00:00
abstract::We report the case of a 15-month-old critically ill child with stimulus-induced diffuse voltage attenuation, a previously unreported electroencephalogram pattern. No clinical evidence of seizure activity was associated with these EEG changes. The patient went on to have a full recovery. This case suggests that critica...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073808324532
更新日期:2009-04-01 00:00:00
abstract::Neurofibromatosis 1 is an autosomal dominant, multisystem disorder with myriad clinical manifestations. Between 1991 and 1998, 495 adults and children were diagnosed with neurofibromatosis 1 at a specialized neurogenetics clinic in Sydney, Australia. This review establishes the prevalence of the clinical manifestation...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380201700812
更新日期:2002-08-01 00:00:00
abstract::Sonography of the posterior fontanelle is easily performed and yields exquisite details of the outline of the major structures of the posterior fossa and the tentorium. These structures are more clearly outlined through the posterior fontanelle than via the traditional anterior fontanelle approach, probably because th...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073889004001s10
更新日期:1989-01-01 00:00:00
abstract::Sandhoff's disease is a rare, genetic lysosomal storage disease leading to delayed myelination or demyelination. Although neuroimaging findings in this disease have been reported previously, magnetic resonance spectroscopy findings have not been reported. In this report, we present magnetic resonance imaging and magne...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738030180061201
更新日期:2003-06-01 00:00:00
abstract::Möbius' syndrome is a rare congenital anomaly characterized by paralysis of the 7th and other cranial nerves and musculoskeletal abnormalities. We report a patient with Möbius' syndrome associated with arthrogryposis and mega cisterna magna in addition to the classic components of this syndrome. The case is interestin...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/08830738040190010710
更新日期:2004-01-01 00:00:00
abstract::During the 4-year period, 1982-1986, 18 patients presented to the Children's Hospital, Camperdown, Sydney, with the following features: (1) Recurrent "absences" clinically indistinguishable from childhood absence epilepsy, (2) Normal clinical examination, (3) Electroencephalogram (EEG) demonstrating normal waking back...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389000500403
更新日期:1990-10-01 00:00:00
abstract::To document the impact of Tourette syndrome on the health care needs of children and access to health care among youth with Tourette syndrome, parent-reported data from the 2007-2008 National Survey of Children's Health were analyzed. Children with Tourette syndrome had more co-occurring mental disorders than children...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073812465121
更新日期:2013-12-01 00:00:00
abstract::We retrospectively analyzed the medical documentation of 194 children infected with Epstein-Barr virus. The diagnosis was based on clinical symptoms and the presence of the viral capsid antigen IgM antibody. Patients with severe neurologic complications also underwent neurologic examination, magnetic resonance imaging...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073815613563
更新日期:2016-05-01 00:00:00
abstract::The sphenoid sinus is often referred to as the "neglected sinus." Isolated sphenoid sinusitis is a rare disease with potentially devastating complications. It occurs at an incidence of about 2.7% of all sinus infections. Although headache is the most common presenting symptom, there is no typical headache pattern. Thr...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380101601203
更新日期:2001-12-01 00:00:00