Clinical strategies to enhance nerve regeneration in composite tissue allotransplantation.

Abstract:

:Reinnervation of a hand transplant ultimately dictates functional recovery but provides a significant regenerative challenge. This article highlights interventions to enhance nerve regeneration through acceleration of axonal regeneration or augmentation of Schwann cell support and discuss their relevance to composite tissue allotransplantation. Surgical techniques that may be performed at the time of transplantation to optimize intrinsic muscle recovery--including appropriate alignment of ulnar nerve motor and sensory components, transfer of the distal anterior interosseous nerve to the recurrent motor branch of the median nerve, and prophylactic release of potential nerve entrapment points--are also presented.

journal_name

Hand Clin

journal_title

Hand clinics

authors

Glaus SW,Johnson PJ,Mackinnon SE

doi

10.1016/j.hcl.2011.07.002

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

495-509, ix

issue

4

eissn

0749-0712

issn

1558-1969

pii

S0749-0712(11)00061-8

journal_volume

27

pub_type

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