Tubulopapillary hidradenoma-like tumor of the mandible: Two case reports of an underrecognized entity.

abstract：OBJECTIVES:Chemoradiation is the treatment of choice for carcinomas of the pharynx and larynx with imminent loss of organ or function. However, the prognosis after CRT decreases when salvage surgery becomes necessary. Single-cycle induction chemotherapy is therefore performed to identify patients who would benefit more...

journal_title：Oral oncology

authors： Semrau S,Schmidt D,Lell M,Waldfahrer F,Lettmaier S,Kuwert T,Iro H,Fietkau R

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Nasopharyngeal carcinoma (NPC) is common in Southeast Asia. Due to the influx of immigrants from this region, the incidence in British Columbia is increasing. Current literature from non-endemic populations encompasses heterogeneous cohorts. This study examines NPC in a North American population, with a high ...

journal_title：Oral oncology

authors： Howlett J,Hamilton S,Ye A,Jewett D,Riou-Green B,Prisman E,Thamboo A

更新日期：2021-01-24 00:00:00

abstract：:Betel quid (BQ) and matrix metalloproteinase-8 (MMP-8) play roles in oral diseases. Here, we analyzed the regulation of MMP-8 by BQ and its effect on cell migration. We found that BQ extract (BQE) increased the secretion of an 85kDa caseinolytic proteinase, specifically precipitated by an anti-MMP-8 antibody, in the c...

journal_title：Oral oncology

authors： Liu SY,Liu YC,Huang WT,Huang GC,Chen TC,Lin MH

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Hypothesizing that neck-level specific locations of residual lymph node metastases following chemoradiation for head and neck cancer are highly predictable, the efficacy of the more targeted lymphadenectomy procedure called super-selective neck dissection (SSND) was evaluated. METHODS:A retrospective analys...

journal_title：Oral oncology

authors： Robbins KT,Dhiwakar M,Vieira F,Rao K,Malone J

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:Feeding tubes are placed unnecessarily in a proportion of head and neck cancer (HNC) patients treated with chemoradiotherapy (CRT) when prophylactic tube placement protocols are used. This may have a negative impact on the risk of long-term dysphagia. Reactive tube placement protocols, on the other hand, mig...

journal_title：Oral oncology

authors： Karsten RT,Stuiver MM,van der Molen L,Navran A,de Boer JP,Hilgers FJM,Klop WMC,Smeele LE

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:To assess the effect of the histological margins (HM) upon locoregional failure (LRF) and overall survival (OS) for oral tongue squamous cell carcinoma (OTSCC). MATERIALS AND METHODS:We undertook a retrospective review of 258 patients, across two institutions, treated for OTSCC between 2007 and 2016. A Cox-...

journal_title：Oral oncology

authors： Daniell J,Udovicich C,Rowe D,McDowell L,Vital D,Bressel M,Magarey MJR,Iseli TA,Wong T,Lekgabe E,Cavanagh K,Fua T,Rischin D,Wiesenfeld D

更新日期：2020-12-01 00:00:00

abstract：:The submental artery island flap (SIF) is gaining acceptance as a simple and reliable option in selected oral oncologic reconstructions. The present study aims to assess the usefulness of submental artery flap in oral reconstruction with respect to flap reliability, cosmesis, function, donor site morbidity and oncolog...

journal_title：Oral oncology

authors： Sebastian P,Thomas S,Varghese BT,Iype EM,Balagopal PG,Mathew PC

更新日期：2008-11-01 00:00:00

abstract：:The etiology of oral squamous cell carcinoma has been linked to environmental carcinogens, such as activated aromatic heterocyclic radicals and epoxides. Our previous work on implantable and 7,12-dimethylbenz[a]anthracene (DMBA)-induced breast cancer showed that oral glutamine (GLN) inhibited tumor growth possibly thr...

journal_title：Oral oncology

authors： Lim V,Korourian S,Todorova VK,Kaufmann Y,Klimberg VS

更新日期：2009-02-01 00:00:00

abstract：:Over the years, several tumor biomarkers have been suggested to foresee the prognosis oral squamous cell carcinoma (OSCC) patients. Here, we present a systematic review to identify, evaluate and summarize the evidence for OSCC reported markers. Eligible studies were identified through a literature search of MEDLINE/Pu...

journal_title：Oral oncology

authors： Rivera C,Oliveira AK,Costa RAP,De Rossi T,Paes Leme AF

更新日期：2017-09-01 00:00:00

abstract：:To examine the influence of smoking on observer based morbidity scores and patient assessed health related quality of life after treatment for head and neck cancer. The results of EORTC C30 and H&N35 questionnaires and DAHANCA morbidity scores were studied according to smoking status in 114 recurrence free head and ne...

journal_title：Oral oncology

authors： Jensen K,Jensen AB,Grau C

更新日期：2007-02-01 00:00:00

abstract：:Emerging evidence suggests the existence of a tumorigenic population of cancer cells that demonstrate stem cell-like properties such as self-renewal and multipotency. These cells, termed cancer stem cells (CSC), are able to both initiate and maintain tumor formation and progression. Studies have shown that CSC are res...

journal_title：Oral oncology

authors： Adams A,Warner K,Nör JE

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVES:Intact cell peptidome profiling (ICPP) with MALDI-ToF Mass Spectrometry holds promise as a non-invasive method to detect head and neck squamous cell carcinoma (HNSCC) objectively, which may significantly improve the early diagnosis of oral cancer. The present study was designed to discriminate between tumour...

journal_title：Oral oncology

authors： Maurer K,Eschrich K,Schellenberger W,Bertolini J,Rupf S,Remmerbach TW

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:The use of transoral robotic surgery (TORS) and laser microsurgery (TLM) in the diagnosis and identification of the site of the unknown primary has become increasingly common. This systematic review and meta-analysis aims to assess the use and efficacy of TORS and TLM for this indication. METHOD:Systematic ...

journal_title：Oral oncology

authors： Farooq S,Khandavilli S,Dretzke J,Moore D,Nankivell PC,Sharma N,Almeida JR,Winter SC,Simon C,Paleri V,De M,Siddiq S,Holsinger C,Ferris RL,Mehanna H

更新日期：2019-04-01 00:00:00

abstract：:The recently identified single nucleotide polymorphism in the MDM2 promoter (SNP 309) may contribute to the early onset of both sporadic and hereditary malignancies in patients with defective p53. We tested this hypothesis by examining the effects of combined MDM2 polymorphisms and somatic p53 mutations on 351 oral sq...

journal_title：Oral oncology

authors： Huang SF,Chen IH,Liao CT,Wang HM,Liou SH,Hsieh LL

更新日期：2009-01-01 00:00:00

abstract：:The epidemiological link between human papillomavirus (HPV) DNA and basaloid squamous cell carcinoma (BSCC) of the pharynx was studied. The expression of p53 protein was evaluated by immunohistochemical analysis. The presence of HPV DNA was evaluated by polymerase chain reaction amplification and "in situ" hybridizati...

journal_title：Oral oncology

authors： Cabanillas R,Rodrigo JP,Ferlito A,Rinaldo A,Fresno MF,Aguilar C,Alvarez ME,Suárez C

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVES:Head and neck squamous cell carcinomas (HNSCCs) exhibit great biological heterogeneity and relatively poor prognosis. Tobacco and alcohol consumption is involved in the cause of the majority of these cancers, but over the last several years, Human Papilloma Virus (HPV) infection has increased specifically in...

journal_title：Oral oncology

authors： Kindt N,Descamps G,Seminerio I,Bellier J,Lechien JR,Pottier C,Larsimont D,Journé F,Delvenne P,Saussez S

更新日期：2016-11-01 00:00:00

abstract：:A unique case of bilateral mucoepidermoid carcinoma arising in pre-existing bilateral Warthin's tumours of the parotid glands is presented. Reports of carcinomas arising in pre-existing unilateral Warthin's tumours are likewise rare with only 3 cases of concern mucoepidermoid carcinoma. This is the first report of bil...

journal_title：Oral oncology

authors： Seifert G

更新日期：1997-07-01 00:00:00

abstract：:Yeasts that are resistant to azole antifungal drugs are increasingly isolated from the mouths of cancer patients suffering from oral fungal infections. Tea tree oil is an agent possessing antimicrobial properties that may prove useful in the prevention and management of infections caused by these organisms. In this st...

journal_title：Oral oncology

authors： Bagg J,Jackson MS,Petrina Sweeney M,Ramage G,Davies AN

更新日期：2006-05-01 00:00:00

abstract：:Oral cancer has become one of the most aggressive types of cancer, killing 140,000 people worldwide every year. Current treatments for oral cancer include surgery and radiation therapies. These procedures can be very effective; however, they can also drastically decrease the quality of life for survivors. New chemothe...

journal_title：Oral oncology

authors： Retzbach EP,Sheehan SA,Nevel EM,Batra A,Phi T,Nguyen ATP,Kato Y,Baredes S,Fatahzadeh M,Shienbaum AJ,Goldberg GS

更新日期：2018-03-01 00:00:00

abstract：:Tumor-infiltrating lymphocytes (TILs) are considered to represent immune reactions of the host to a malignant tumor. Programmed death receptor ligand-1 (PD-L1) is a surface protein that blocks the function of T lymphocytes and is expressed on cancer cells. Tumor-associated fibroblasts (TAFs), which influence tumor gro...

journal_title：Oral oncology

authors： Cho YA,Yoon HJ,Lee JI,Hong SP,Hong SD

更新日期：2011-12-01 00:00:00

abstract：:Oral cavity and oropharyngeal carcinomas (oral cancer) represents a significant cause of morbidity and mortality. Despite efforts in improving early diagnosis and treatment, the 5-year survival rate of advanced stage of the disease is less than 63%. The field of nanomedicine has offered promising diagnostic and therap...

journal_title：Oral oncology

authors： Marcazzan S,Varoni EM,Blanco E,Lodi G,Ferrari M

更新日期：2018-01-01 00:00:00

abstract：:The Wnt pathway is involved in carcinogenesis and three regulatory genes of the Wnt pathway, APC (adenomatous polyposis coli), beta-catenin and Axin are frequently mutated in some primary human cancers. This study was conducted to clarify the relation of beta-catenin accumulation and the mutation of the CTNNB1 (beta-c...

journal_title：Oral oncology

authors： Siriwardena BS,Kudo Y,Ogawa I,Tilakaratne WM,Takata T

更新日期：2009-02-01 00:00:00

abstract：:Prophylactic internal fixation (PIF), with a bone plate in either the anterior (over the section defect) or posterior (on intact cortex) position, has substantially reduced the incidence of fracture at the donor site of the radial osteocutaneous free flap. This study uses the sheep tibia model to compare the effective...

journal_title：Oral oncology

authors： Avery CM,Skidmore M,Peden A,Pan J

更新日期：2011-04-01 00:00:00

abstract：:To understand the role of 70 kDa heat shock protein (HSP70) in the pathogenesis of oral cancer, its expression was studied in human normal, premalignant and malignant oral mucosa. Cell surface expression of HSP70 was assessed in oral tissue specimens by flow cytometric analysis using a mouse monoclonal antibody agains...

journal_title：Oral oncology

authors： Kaur J,Das SN,Srivastava A,Ralhan R

更新日期：1998-03-01 00:00:00

abstract：:Immunotherapy (IO) with anti-PD1 inhibitors is available for the treatment of recurrent/metastatic squamous cell carcinomas of the head and neck (SCCHD) since 2016. Both nivolumab and pembrolizumab were tested in phase 3 randomized trials in adults progressing on or after platinum-based therapy and were found to confe...

journal_title：Oral oncology

authors： Kokkali S,Ntokou A,Drizou M,Perdikari K,Makaronis P,Katsarou E,Koufopoulos N,Tzovaras A,Ardavanis A

更新日期：2020-02-01 00:00:00

abstract：:The history of mucositis is as old as radiation- and chemotherapy. Despite being regularly reported and documented as one of the worst side effects of cancer therapy, relatively little was appreciated about the complexities of mucositis' pathogenesis until relatively recently. More frustrating for patients and clinici...

journal_title：Oral oncology

authors： Sonis ST

更新日期：2009-12-01 00:00:00

abstract：:Vocal process granulomas are benign lesions involved in the healing of posterior glottis injuries. Here, we report the results of our conservative treatment of vocal process granulomas. Fifty-three patients with 54 occurrences of granulomas between 1998 and 2007 were enrolled. All patients were observed without surgic...

journal_title：Oral oncology

authors： Wang CP,Ko JY,Wang YH,Hu YL,Hsiao TY

更新日期：2009-09-01 00:00:00

abstract：:We investigated the knowledge and behaviors of a random sample of 500 primary care physicians (PCPs) regarding oral cancer in Calabria (Italy). 87.6% and 64% indicated tobacco and alcohol use as risk factors, only 31.5% and 2.8% having a prior oral cancer lesion and older age. 60.9% knew that squamous-cell carcinoma i...

journal_title：Oral oncology

authors： Nicotera G,Di Stasio SM,Angelillo IF

更新日期：2004-05-01 00:00:00

abstract：:Forty-four patients with head and neck malignancies were included in a prospective, randomized, double-blind, placebo-controlled study for evaluation of sucralfate in prevention of oral mucositis induced by radiation therapy. Patients were randomized to receive oral suspensions of either sucralfate (n = 23) or placebo...

journal_title：Oral oncology

authors： Etiz D,Erkal HS,Serin M,Küçük B,Hepari A,Elhan AH,Tulunay O,Cakmak A

更新日期：2000-01-01 00:00:00

abstract：:Squamous cell carcinoma of the pharynx and larynx (SCCPL) is a genetically complex disease and is frequently associated with nonrandom chromosomal alterations. Fifty primary SCC of the pharynx (oropharynx, n=11): see and hypopharynx, n=11) and larynx ( n=28) were examined for numerical aberrations of chromosomes 8, 9,...

journal_title：Oral oncology

authors： Hardisson D,Alvarez-Marcos C,Salas-Bustamante A,Alonso-Guervós M,Sastre N,Sampedro A

更新日期：2004-04-01 00:00:00