Experimental characterization of lateral profiles of scanned proton and carbon ion pencil beams for improved beam models in ion therapy treatment planning.

abstract：:By means of a transonic gas jet, gene guns ballistically deliver microparticle formulations of drugs and vaccines to the outer layers of the skin or mucosal tissue to induce unique physiological responses for the treatment of a range of conditions. Reported high-speed imaging experiments show that the mucosa deforms s...

journal_title：Physics in medicine and biology

authors： Hardy MP,Kendall MA

更新日期：2005-10-07 00:00:00

abstract：:A method is described whereby, utilising a biocompatible magnetic glass-ceramic material, effective hysteresis heating in living tissue was accomplished. Initial experiments on mice showed that a significant heating effect can be obtained in the ceramic-impregnated regions. An analysis is also given for the projected ...

journal_title：Physics in medicine and biology

authors： Borrelli NF,Luderer AA,Panzarino JN

更新日期：1984-05-01 00:00:00

abstract：:The temperature sensitivities of absorption and reduced scattering coefficients in the range 700-1000 nm are determined for the liquid phantom Intralipid using spatially resolved continuous wave measurements. The measurements were conducted on a 10 L heated volume of 1% Intralipid subjected to a 40-30 degrees C coolin...

journal_title：Physics in medicine and biology

authors： McGlone VA,Martinsen P,Künnemeyer R,Jordan B,Cletus B

更新日期：2007-05-07 00:00:00

abstract：:Modern Monte Carlo codes allow for the calculation of ion chamber specific beam quality correction factors k(Q), which are needed for dosimetry in radiotherapy. While statistical (type A) uncertainties of the calculated data can be minimized sufficiently, the influence of systematic (type B) uncertainties is mostly un...

journal_title：Physics in medicine and biology

authors： Wulff J,Heverhagen JT,Zink K,Kawrakow I

更新日期：2010-08-21 00:00:00

abstract：:A method is presented for extraction of intra and inter fraction motion of seeds/markers within the patient from cone beam CT (CBCT) projection images. The position of the marker is determined on each projection image and fitted to a function describing the projection of a fixed point onto the imaging panel at differe...

journal_title：Physics in medicine and biology

authors： Marchant TE,Amer AM,Moore CJ

更新日期：2008-02-21 00:00:00

abstract：:There is a need to verify the accuracy of general purpose Monte Carlo codes like EGSnrc, which are commonly employed for investigations of dosimetric problems in radiation therapy. A number of experimental benchmarks have been published to compare calculated values of absorbed dose to experimentally determined values....

journal_title：Physics in medicine and biology

authors： Renner F,Wulff J,Kapsch RP,Zink K

更新日期：2015-10-07 00:00:00

abstract：:Radiochromic films are useful as dosimeters in high-precision radiotherapy owing to their high spatial resolution. However, when a particle beam is measured using a radiochromic film, the dose cannot be estimated accurately because the film darkness varies with variations in linear energy transfer (LET). This paper pr...

journal_title：Physics in medicine and biology

authors： Kawashima M,Matsumura A,Souda H,Tashiro M

更新日期：2020-06-15 00:00:00

abstract：:The aim of this study was to measure entrance skin doses on patients undergoing cone-beam computed tomography (CBCT) examinations, to establish conversion factors between skin and organ doses, and to estimate cancer risk from CBCT exposures. 266 patients (age 8-83) were included, involving three imaging centres. CBCT ...

journal_title：Physics in medicine and biology

authors： Pauwels R,Cockmartin L,Ivanauskaité D,Urbonienė A,Gavala S,Donta C,Tsiklakis K,Jacobs R,Bosmans H,Bogaerts R,Horner K,SEDENTEXCT Project Consortium.

更新日期：2014-07-21 00:00:00

abstract：:A detailed Monte Carlo model of a proton therapy treatment head was commissioned to simulate the delivery of small field proton treatments. Small fields are challenging in the planning and quality assurance process because of aperture scattering and dosimetric disequilibrium. Four patients with small fields used in al...

journal_title：Physics in medicine and biology

authors： Bednarz B,Daartz J,Paganetti H

更新日期：2010-12-21 00:00:00

abstract：:The measurement of output factors (OF) for the small photon beams generated by Leksell Gamma Knife® (LGK) radiotherapy units is a challenge for the physicist due to the under or over estimation of these factors by a vast majority of the detectors commercially available. Output correction factors, introduced in the int...

journal_title：Physics in medicine and biology

authors： Benmakhlouf H,Johansson J,Paddick I,Andreo P

更新日期：2015-05-21 00:00:00

abstract：:The use of deformable image registration methods in the context of adaptive radiotherapy leads to uncertainties in the simulation of the administered dose distributions during the treatment course. Evaluation of these methods is a prerequisite to decide if a plan adaptation will improve the individual treatment. Curre...

journal_title：Physics in medicine and biology

authors： Teske H,Bartelheimer K,Meis J,Bendl R,Stoiber EM,Giske K

更新日期：2017-06-21 00:00:00

abstract：:In CT imaging, a variety of applications exist which are strongly SNR limited. However, in some cases redundant data of the same body region provide additional quanta. Examples in dual energy CT, the spatial resolution has to be compromised to provide good SNR for material decomposition. However, the respective spectr...

journal_title：Physics in medicine and biology

authors： Bruder H,Raupach R,Sunnegardh J,Allmendinger T,Klotz E,Stierstorfer K,Flohr T

更新日期：2015-11-07 00:00:00

abstract：:The feasibility is demonstrated of a numerical method to calculate dose deposition by broad high-energy electron beams in homogeneous matter or in heterogeneous matter in which the heterogeneities are arranged in slabs perpendicular to the beam axis. The method is based only on the basic physical interaction processes...

journal_title：Physics in medicine and biology

authors： Huizenga H,Storchi PR

更新日期：1989-10-01 00:00:00

abstract：:Pinhole SPECT is rapidly gaining popularity for imaging laboratory animals using gamma-emitting molecules. Penetration and scattering of gamma radiation in the pinhole edge material can account for a significant fraction of the total number of photons detected, particularly if the pinholes have small diameters. This s...

journal_title：Physics in medicine and biology

authors： van der Have F,Beekman FJ

更新日期：2004-04-21 00:00:00

abstract：:To investigate the profile measurement capabilities of an IBA-Dosimetry scintillation detector and to assess its feasibility for determining the low-intensity tails of pencil-beam scanning spots, the responses of the scintillation detector and Gafchromic EBT2 film to a 115 MeV proton spot were measured in-air at the i...

journal_title：Physics in medicine and biology

authors： Lin L,Ainsley CG,Mertens T,De Wilde O,Talla PT,McDonough JE

更新日期：2013-06-21 00:00:00

abstract：:An extensive study on specific absorption rate (SAR) covering 720 simulations and 15 voxel models (18-105 kg) has been performed by applying the parallel finite-difference time-domain method. High-resolution whole-body models have been irradiated with plane waves from 300 MHz to 5 GHz by applying various incoming dire...

journal_title：Physics in medicine and biology

authors： Uusitupa T,Laakso I,Ilvonen S,Nikoskinen K

更新日期：2010-02-21 00:00:00

abstract：:Incorrect prediction of skin dose in external beam radiotherapy (EBR) can have normal tissue complication such as acute skin desquamation and skin necrosis. The absorbed dose of skin should be evaluated within basal layer, placed between the epidermis and dermis layers. However, current treatment planning systems (TPS...

journal_title：Physics in medicine and biology

authors： Cheon BW,Yoo DH,Shin WG,Choi HJ,Park HJ,Kim JI,Min CH

更新日期：2019-08-14 00:00:00

abstract：:Numerous studies of early-stage breast cancer treated with breast conserving surgery (BCS) and radiotherapy (RT) have been published in recent years. Both external beam radiotherapy (EBRT) and/or brachytherapy (BT) with different fractionation schemes are currently used. The present RT practice is largely based on emp...

journal_title：Physics in medicine and biology

authors： Guerrero M,Li XA

更新日期：2003-10-21 00:00:00

abstract：:Cavity theories are used to relate the dose in a medium to the dose in a cavity. No satisfactory analytical approach exists for the case of intermediate cavities, such as TLDs, when interface effects are important. Burlin proposed a general cavity theory that accounts for the cavity size but which ignores interface ef...

journal_title：Physics in medicine and biology

authors： Frujinoiu C

更新日期：2001-04-01 00:00:00

abstract：:Deformable image registration is widely used in various radiation therapy applications including daily treatment planning adaptation to map planned tissue or dose to changing anatomy. In this work, a simple and efficient inverse consistency deformable registration method is proposed with aims of higher registration ac...

journal_title：Physics in medicine and biology

authors： Yang D,Li H,Low DA,Deasy JO,El Naqa I

更新日期：2008-11-07 00:00:00

abstract：:Histotripsy is an ultrasound ablation method that depends on the initiation of a cavitation bubble cloud to fractionate soft tissue. Although previous work has provided significant insight into the process of intrinsic threshold histotripsy, the majority of these studies have used highly focused (i.e. f-number  <  0.6...

journal_title：Physics in medicine and biology

authors： Vlaisavljevich E,Gerhardson T,Hall T,Xu Z

更新日期：2017-02-21 00:00:00

abstract：:Recently, there has been an increased interest in flattening-filter-free (FFF) linear accelerators. Removal of the filter results in available dose rates up to 24 Gy min(-1) (for nominal energy 10 MV in depth of maximum dose, a source-surface distance of 100 cm and a field size of 10×10 cm2). To guarantee accurate rel...

journal_title：Physics in medicine and biology

authors： Lang S,Hrbacek J,Leong A,Klöck S

更新日期：2012-05-07 00:00:00

abstract：:The weak absorption of shortwave infrared light by skin tissues between 700 and 1500 nm offers an important window for diagnosis by optical means. The strong scattering of shortwave infrared light by the skin, however, presents a challenge to the modelling of light propagation through the skin and the understanding of...

journal_title：Physics in medicine and biology

authors： Du Y,Hu XH,Cariveau M,Ma X,Kalmus GW,Lu JQ

更新日期：2001-01-01 00:00:00

abstract：:Radiotherapy treatment planning relies on the use of geometrically correct images. This paper presents a fully automatic tool for correcting MR images for the effects of B(0) inhomogeneities. The post-processing method is based on the gradient-reversal technique of Chang and Fitzpatrick (1992 IEEE Trans. Med. Imaging ...

journal_title：Physics in medicine and biology

authors： Reinsberg SA,Doran SJ,Charles-Edwards EM,Leach MO

更新日期：2005-06-07 00:00:00

abstract：:Technical advances towards high resolution PET imaging try to overcome the inherent physical limitations to spatial resolution. Positrons travel in tissue until they annihilate into the two gamma photons detected. This range is the main detector-independent contribution to PET imaging blurring. To a large extent, it c...

journal_title：Physics in medicine and biology

authors： Cal-González J,Herraiz JL,España S,Corzo PM,Vaquero JJ,Desco M,Udias JM

更新日期：2013-08-07 00:00:00

abstract：:Simultaneous dual-radionuclide myocardial perfusion/innervation SPECT imaging can provide important information about the mismatch between scar tissue and denervated regions. The Siemens IQ-SPECT system developed for cardiac imaging uses a multifocal SMARTZOOM collimator to achieve a four-fold sensitivity for the card...

journal_title：Physics in medicine and biology

authors： Du Y,Bhattacharya M,Frey EC

更新日期：2014-06-07 00:00:00

abstract：:Awake and/or freely moving small animal single photon emission imaging allows the continuous study of molecules exhibiting slow kinetics without the need to restrain or anaesthetise the animals. Estimating motion free projections in freely moving small animal planar imaging can be considered as a limited angle tomogra...

journal_title：Physics in medicine and biology

authors： Angelis GI,Ryder WJ,Gillam JE,Boisson F,Kyme AZ,Fulton RR,Meikle SR,Kench PL

更新日期：2017-05-21 00:00:00

abstract：:Measurements of lung nodule volume with multi-detector computed tomography (MDCT) have been shown to be more accurate and precise compared to conventional lower dimensional measurements. Quantifying the size of lesions is potentially more difficult when the object-to-background contrast is low as with lesions in the l...

journal_title：Physics in medicine and biology

authors： Li Q,Gavrielides MA,Zeng R,Myers KJ,Sahiner B,Petrick N

更新日期：2015-01-21 00:00:00

abstract：:To achieve accurate and fast deformable image registration (DIR) for pulmonary CT, we proposed a Multi-scale DIR framework with unsupervised Joint training of Convolutional Neural Network (MJ-CNN). MJ-CNN contains three models at multi-scale levels for a coarse-to-fine DIR to avoid being trapped in a local minimum. It...

journal_title：Physics in medicine and biology

authors： Jiang Z,Yin FF,Ge Y,Ren L

更新日期：2020-01-13 00:00:00

abstract：:The problem of fluorescence diffuse optical tomography consists in localizing fluorescent markers from near-infrared light measurements. Among the different available acquisition modalities, the time-resolved modality is expected to provide measurements of richer information content. To extract this information, the m...

journal_title：Physics in medicine and biology

authors： Ducros N,Hervé L,Da Silva A,Dinten JM,Peyrin F

更新日期：2009-12-07 00:00:00