Abstract：
:Cardiac resynchronization therapy (CRT) is an important therapy for patients with heart failure and conduction pathology, but the benefits are heterogeneous between patients and approximately a third of patients do not show signs of clinical or echocardiographic response. This calls for a better understanding of the underlying conduction disease and resynchronization. In this review, we discuss to what extent established and novel animal models can help to better understand the pathophysiology of dyssynchrony and the benefits of CRT.
journal_name
J Cardiovasc Transl Resjournal_title
Journal of cardiovascular translational researchauthors
Strik M,van Middendorp LB,Vernooy Kdoi
10.1007/s12265-011-9336-5subject
Has Abstractpub_date
2012-04-01 00:00:00pages
135-45issue
2eissn
1937-5387issn
1937-5395journal_volume
5pub_type
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