Abstract:
:There are four cone morphologies in zebrafish, corresponding to UV (U), blue (B), green (G), and red (R)-sensing types; yet genetically, eight cone opsins are expressed. How eight opsins are physiologically siloed in four cone types is not well understood, and in larvae, cone physiological spectral peaks are unstudied. We use a spectral model to infer cone wavelength peaks, semisaturation irradiances, and saturation amplitudes from electroretinogram (ERG) datasets composed of multi-wavelength, multi-irradiance, aspartate-isolated, cone-PIII signals, as compiled from many 5- to 12-day larvae and 8- to 18-month-old adult eyes isolated from wild-type (WT) or roy orbison (roy) strains. Analysis suggests (in nm) a seven-cone, U-360/B1-427/B2-440/G1-460/G3-476/R1-575/R2-556, spectral physiology in WT larvae but a six-cone, U-349/B1-414/G3-483/G4-495/R1-572/R2-556, structure in WT adults. In roy larvae, there is a five-cone structure: U-373/B2-440/G1-460/R1-575/R2-556; in roy adults, there is a four-cone structure, B1-410/G3-482/R1-571/R2-556. Existence of multiple B, G, and R types is inferred from shifts in peaks with red or blue backgrounds. Cones were either high or low semisaturation types. The more sensitive, low semisaturation types included U, B1, and G1 cones [3.0-3.6 log(quanta·μm-2·s-1)]. The less sensitive, high semisaturation types were B2, G3, G4, R1, and R2 types [4.3-4.7 log(quanta·μm-2·s-1)]. In both WT and roy, U- and B- cone saturation amplitudes were greater in larvae than in adults, while G-cone saturation levels were greater in adults. R-cone saturation amplitudes were the largest (50-60% of maximal dataset amplitudes) and constant throughout development. WT and roy larvae differed in cone signal levels, with lesser UV- and greater G-cone amplitudes occurring in roy, indicating strain variation in physiological development of cone signals. These physiological measures of cone types suggest chromatic processing in zebrafish involves at least four to seven spectral signal processing pools.
journal_name
Vis Neuroscijournal_title
Visual neuroscienceauthors
Nelson RF,Balraj A,Suresh T,Torvund M,Patterson SSdoi
10.1017/S0952523819000075subject
Has Abstractpub_date
2019-07-30 00:00:00pages
E010eissn
0952-5238issn
1469-8714pii
S0952523819000075journal_volume
36pub_type
杂志文章abstract::Adult Japanese quail have an endogenous circadian clock located in their eyes that has been shown to regulate melatonin biosynthesis. We investigated if a circadian oscillator is present in cultures of dispersed embryonic quail retina. Melatonin release in retinal cell culture is modulated by the light cycle, indicati...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523899165040
更新日期:1999-09-01 00:00:00
abstract::Effects of ATP on the activity of cGMP-gated channels from carp cone photoreceptors were studied. In 29% of the patches examined (N = 45), ATP (1 mM) enhanced a current evoked by cGMP (20 microM, up to about 100%), in 33%. ATP suppressed it by up to about 90%, and in the remaining 38%, ATP had no effect. ATP showed si...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800012578
更新日期:1997-07-01 00:00:00
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journal_title:Visual neuroscience
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abstract::Extrastriate areas TEO and V4 have been associated with form and color vision. Area V4 has also been suggested to participate in processes concerned with attention, stimulus salience, and perceptual learning. In a continuing effort to elucidate the connectional interactions and microcircuitry of these areas, we descri...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800002480
更新日期:1994-05-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523806230062
更新日期:2006-09-01 00:00:00
abstract::We have studied the influence of chromatic adaptation upon the perceived visual position of a test stimulus using a Vernier alignment task. Maximum and minimum offsets in spatial position are generated when the adapting and test stimuli lie on the same and orthogonal axes in MBDKL color space, respectively. When the t...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523804213426
更新日期:2004-05-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章,评审
doi:10.1017/S0952523810000313
更新日期:2011-01-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800002182
更新日期:1989-01-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800000079
更新日期:1990-07-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523807070666
更新日期:2007-07-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s095252380000403x
更新日期:1991-09-01 00:00:00
abstract::The outer plexiform layer of the retina contains a neural circuit in which cone synaptic terminals are electrically coupled and release glutamate onto wide-field and narrow-field horizontal cells. These are also electrically coupled and feed back through a GABAergic synapse to cones. In cat this circuit's structure is...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800008440
更新日期:1995-05-01 00:00:00
abstract::This study of the tree shrew, Tupaia belangeri, provides evidence for an intracollicular pathway that arises in the superficial gray layer and terminates in the optic layer. As a first step, Nissl, myelin, and cytochrome oxidase stains were used to identify the layers of the superior colliculus in the tree shrew. Seco...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800008464
更新日期:1995-05-01 00:00:00
abstract::Psychophysical research has documented the existence of three processes in light adaptation: a fast subtractive process, a divisive process that is fast at light onset and slower at light offset, and a very slow subtractive process (Hayhoe et al., 1987). In the neural model developed here, the fast subtractive process...
journal_title:Visual neuroscience
pub_type: 杂志文章,评审
doi:10.1017/s0952523800012098
更新日期:1997-05-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800005964
更新日期:1989-11-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800005009
更新日期:1992-05-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523805225087
更新日期:2005-09-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S095252380808084X
更新日期:2009-01-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523804041045
更新日期:2004-01-01 00:00:00
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journal_title:Visual neuroscience
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800002376
更新日期:1994-05-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800006751
更新日期:1995-11-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
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更新日期:1998-11-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523801191066
更新日期:2002-01-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523808080449
更新日期:2008-05-01 00:00:00
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journal_title:Visual neuroscience
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更新日期:2002-07-01 00:00:00
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journal_title:Visual neuroscience
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更新日期:1996-07-01 00:00:00