Abstract：
:This case report concerns an elderly woman referred with a 6-month history of rising and falling fever in the range 38-40°C. She was examined repeatedly by her family doctor and given various antibiotic treatments before being hospitalized in our geriatric unit. Laboratory tests and microbiological studies led to a diagnosis of chronic Q fever, a zoonosis caused by Coxiella burnetii, a Gram-negative obligate intracellular coccobacillus; humans usually become infected by inhaling infectious airborne particles. The diagnosis of Q fever relies on serology with enzyme immunoassay (EIA). The main feature of Q fever is its clinical polymorphism: clinical signs may be aspecific and, in chronic cases, patients often do not recall having had the acute infection. As the most frequent and severe manifestation of Q fever is endocarditis, severe consequences may ensue. In our patient, broad-spectrum antibiotics were given before the serology results were available and rapid clinical improvement was achieved. This unusual disease should therefore also be considered in differential diagnosis of fever in the elderly, and age should not be considered as a contraindication for not performing all studies, because timely and adequate treatment is important partly to preserve elderly patients' self-sufficiency and to prevent them from becoming bedridden.
journal_name
Aging Clin Exp Resjournal_title
Aging clinical and experimental researchauthors
Ruggiero E,Inelmen EM,Grosso G,Manzato Edoi
10.3275/8179subject
Has Abstractpub_date
2012-10-01 00:00:00pages
552-4issue
5eissn
1594-0667issn
1720-8319pii
8179journal_volume
24pub_type
杂志文章abstract：BACKGROUND:Multiple chronic conditions affect people's health-related quality of life (QoL) and the distributions of the conditions may differ between genders. Our goal was to examine gender differences in chronic conditions and QoL among community-living elderly in Taiwan and to examine whether differences in QoL betw...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-018-1099-2
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:The SarQoL® is a recently developed quality of life questionnaire specific to sarcopenia. AIM:To compare the quality of life (QoL) of subjects identified as sarcopenic with that of non-sarcopenic subjects when using six different operational definitions of sarcopenia. METHODS:Participants of the SarcoPhAge...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-017-0866-9
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND AND AIMS:Bone structure, geometry and mineral content represent complex traits with a significant heritable component. However, the specific contributing genes have not been unambiguously identified. The aim of the present cross-sectional study was to analyse an association between heel ultrasound measuremen...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324584
更新日期：2005-04-01 00:00:00
abstract：INTRODUCTION:Endogenous brain-derived neurotrophic factor (BDNF) is thought to be protective against the neurodegeneration seen in Parkinson's disease (PD), and is thought to increase during exercise. This has been proposed as a possible mechanism by which exercise improves outcomes for people with PD. We conducted a p...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-019-01353-w
更新日期：2020-09-01 00:00:00
abstract：:The aim of the study was to look firstly at the changes that occurred in depressive symptomatology over a 5-year period among originally 75-year-old residents in three Nordic localities: Glostrup in Denmark, Göteborg in Sweden and Jyväskylä in Finland, and secondly, at some selected variables if they predicted depress...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND:Asymmetric vestibular function, decreased plantar sensation, postural control and functional ability have been associated with fall-related wrist fractures. OBJECTIVE:To investigate whether multi-sensory training (MST) improves postural control, vestibular function, foot sensation and functional ability amo...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s40520-019-01143-4
更新日期：2020-01-01 00:00:00
abstract：:Osseointegration is a term that refers to the formation of a direct interface between an implant and bone without intervening soft tissue. Cementless femoral fixation in total hip arthroplasty is dependent on mechanical and biological factors that affect implant stability and long-term outcome. Osteoporosis leads to m...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-013-0103-0
更新日期：2013-10-01 00:00:00
abstract：:Osteoarthritis (OA) is the most common joint condition and, with a burgeoning ageing population, is due to increase in prevalence. Beyond conventional medical and surgical interventions, there are an increasing number of 'alternative' therapies. These alternative therapies may have a limited evidence base and, for thi...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-020-01515-1
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:We define active aging as a striving for activities as per one's goals, capacities and opportunities. AIM:To test the 1-year counselling intervention effects on active aging. METHODS:In this two-arm single-blinded randomized controlled trial, the intervention group received individually tailored counsellin...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-020-01535-x
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:To determine the association between the level of nutritional risk and the mortality of hospitalized patients with atrial fibrillation. METHODS:In a prospective cohort study, we included patients hospitalized with atrial fibrillation in an internal medicine department in 2007. We calculated the nutritional r...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-019-01152-3
更新日期：2019-12-01 00:00:00
abstract：:Neoplastic diseases may be complicated by rheumatic diseases or may be occur with them. Dermatomyositis/polymyositis and polymyalgia rheumatica are described as paraneoplastic syndromes. We report a case with proximal muscular weakness as only symptom of colon cancer in the absence of other symptoms and laboratory abn...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-013-0034-9
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND:Incisional hernia in aged patients represents a challenge even for experienced surgeons. Besides increased risk of complications due to comorbidities, mesh fixation and assuring a sufficient mesh overlap of the defect are the main issues in carrying out the repair. AIMS:In order to assure broader coverage o...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-016-0651-1
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND AND AIMS:Carotid sinus hypersensitivity (CSH) is a common cause of fainting and falls in the older adult population and is diagnosed by carotid sinus massage (CSM). Previous work has suggested that age-related stiffening of blood vessels reduces afferent input from the carotid sinus leading to central upregu...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.3275/6810
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND:Aging has several effects on auditory processing with the most important effect known as speech perception impairment in noise. AIMS:The aim of the present study was to investigate the effects of aging on spatial hearing using quick speech in noise (QSIN) and binaural masking level difference (BMLD) tests a...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-019-01233-3
更新日期：2020-04-01 00:00:00
abstract：:Most visual and cognitive functions are affected by aging over the lifespan. In this study, our aim was to investigate the loss in sensitivity to different classes of second-order stimuli-a class of stimuli supposed to be mainly processed in extrastriate cortex-in the aging population. These stimuli will then allow on...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-018-1018-6
更新日期：2019-05-01 00:00:00
abstract：OBJECTIVE:Attitude of healthcare providers toward older people is very important in the aging world. Neurologists contact older adults very frequently. We aimed to investigate the attitudes of neurologists toward older adults. MEASUREMENTS:We recorded participants age; sex; duration of clinical practice in neurology; ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-016-0606-6
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:Oxidative stress is strongly associated with aging and age-related diseases and plays a crucial role in endothelial dysfunction development. AIM:To better understand the molecular mechanisms of aging and stress response in humans, we examined changes to young and older human endothelial cells over time (72,...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-015-0357-9
更新日期：2015-08-01 00:00:00
abstract：BACKGROUND:Identification of predictive factors on institutionalization provides the basis for the development and application of preadmission assessment. There is a lack of evidence for predictors of institutionalization for older people. AIMS:To examine the effect of predictive factors on institutionalization in hom...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,收录出版
doi：10.1007/s40520-016-0722-3
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND:Frailty is a public health concern in the ageing population. Little is known about the role of gender in the relationship between frailty and health care utilization in older adults. AIMS:The study aims to examine gender differences in the association between different frailty status and health care utiliza...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-019-01410-4
更新日期：2020-10-01 00:00:00
abstract：:Age-related macular disease (AMD) is the leading cause of legal blindness among the elderly in Western nations. The magnitude of the problem will undoubtedly grow, as age is a significant risk factor and the number of people aged 65 and over is projected to increase. The most frequent cause of severe visual loss assoc...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/BF03327409
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND:Alzheimer's disease (AD) research progress is impeded due to participant recruitment challenges. This study seeks to better understand, from the perspective of individuals engaged in clinical trials (CTs), research motivations. METHODS:Participants, or their caregivers, from AD treatment and prevention CTs ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-017-0771-2
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Most studies on atrial fibrillation (AF) epidemiology, treatment, and outcomes have included mainly Caucasians patients. The world literature on AF in other ethnicities is very limited particularly in the elderly. AIMS:The aim of this study was to compare the clinical characteristics, treatment and outcome ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.3275/8757
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:Despite the increase in research on delirium, it remains underdiagnosed and difficult to manage, and the outcome is poor especially in older people. AIMS:To identify the clinically diagnosed rates of delirium, the possible aetiologies, to describe treatment, number and type of psychotropic medication used a...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-014-0227-x
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND AND AIMS:The MDS inter- RAI Acute Care is a comprehensive geriatric assessment tool for hospitalized older persons. The aim was to examine its validity based on test content by use in daily clinical practice. METHODS:Clinical staff of multiple disciplines assessed 256 older persons (83.2±5.2 years; 60% fema...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,多中心研究
doi：10.1007/BF03325244
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The clinical problems and needs of our oldest old (≥85 years) are often substantially different from those of younger patients, and are arguably different from younger elderly patients (age 65-84). With the increasing number of frail oldest olds residing in Nursing Homes (NH), we aim to identi...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-013-0145-3
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND:It is unclear whether motor-cognitive dual tasks predict cognitive decline better than either motor or cognitive tasks alone. AIMS:To examine the utility of the novel motor-cognitive dual-task test [Stepping Trail Making Test (S-TMT)], as a predictor of cognitive decline, and compare its predictive performa...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-020-01714-w
更新日期：2020-09-23 00:00:00
abstract：OBJECTIVES:In the last decade, there has been a rapid increase in the number of elderly patients referred for cardiac surgery. Recent studies have identified risk factors for prolonged intensive care unit (ICU) stay in cardiac surgery patients. The aims of this study was to evaluate pre-operative risk factors for ICU s...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.3275/8521
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:In addition to the normal process of ageing, frailty, defined as a geriatric syndrome, is becoming more prevalent. Around 10% of people over 65 years and 25-50% of those aged over 85 years are frail. Frail elderly are more vulnerable to external stressors and have an increased risk of adverse health outcomes...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-018-0918-9
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND AND AIMS:Functional brain imaging has shown that bilateral brain reorganization may occur after unilateral cerebral damage. The present study searched for evidence of bilateral motor control changes in gait in patients with chronic unilateral stroke. METHODS:Gait variables (temporal and spatial parameters, ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324759
更新日期：2008-04-01 00:00:00
abstract：BACKGROUND:Life-space assessment incorporates all movements in terms of the distance from home, the frequency of movement and the need of assistance for movement. Executive function (EF) is an important higher order cognitive ability that controls and guides people's goal-directed actions. We examined the cross-section...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-017-0762-3
更新日期：2018-02-01 00:00:00
