Effectiveness of pharmaceutical care for drug treatment adherence in women with lupus nephritis in Rio de Janeiro, Brazil: a randomized controlled trial.

abstract：BACKGROUND AND OBJECTIVES:Pregnancies in women with systemic lupus erythematosus (SLE) and lupus nephritis are considered high-risk due to high rates of maternal and fetal complications. However, there has not been a formal analysis addressing the issue of maternal deaths in these women. The aim of this study was to pe...

journal_title：Lupus

authors： Ritchie J,Smyth A,Tower C,Helbert M,Venning M,Garovic V

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:In a previous study performed 9 ± 3.6 years ago, 74 asymptomatic patients with systemic lupus erythematosus (SLE) and/or antiphospholipid syndrome (APS) underwent lung function testing. A significantly low diffusion capacity (DLCO) ranging from 45% to 70% was recorded in 28 of the 74 (37.8%) patients who wer...

journal_title：Lupus

authors： Elalouf O,Fireman E,Levartovsky D,Kaufman I,Rogovski O,Elkayam O,Caspi D,Paran D

更新日期：2015-08-01 00:00:00

abstract：:To determine if neurometabolic changes in the white matter (WM) of systemic lupus erythematosus (SLE) patients may predict the appearance of small hyperintense lesions on T2-weighted magnetic resonance imaging (MRI) inside the magnetic resonance spectroscopy (MRS) region of interest (ROI). We included 30 SLE patients ...

journal_title：Lupus

authors： Appenzeller S,Li LM,Costallat LT,Cendes F

更新日期：2007-01-01 00:00:00

abstract：:Pericardial effusions causing pericardial tamponade are rare in patients with systemic lupus erythematosus (SLE). The goal of this study is to describe in detail the clinical and laboratory characteristics of a group of patients with pericardial effusions and pericardial tamponade secondary to SLE. We retrospectively ...

journal_title：Lupus

authors： Rosenbaum E,Krebs E,Cohen M,Tiliakos A,Derk CT

更新日期：2009-06-01 00:00:00

abstract：:The importance of the immunomodulatory effects of vitamin D has recently been associated with autoimmune and chronic inflammatory diseases. Vitamin D deficiency has been linked to the development of autoimmune conditions. Antiphospholipid syndrome is an autoimmune disease characterized by thrombotic events and obstetr...

journal_title：Lupus

authors： García-Carrasco M,Jiménez-Herrera EA,Gálvez-Romero JL,Mendoza-Pinto C,Méndez-Martínez S,Etchegaray-Morales I,Munguía-Realpozo P,Vázquez de Lara-Cisneros L,Santa Cruz FJ,Cervera R

更新日期：2018-12-01 00:00:00

abstract：:Background and objective African-Americans and Hispanic-Americans with lupus are the two most common minority groups who receive kidney transplants in the USA. It is unknown if African-Americans and Hispanic-Americans with lupus have similar outcomes after kidney transplantation. In this study, we assessed whether Afr...

journal_title：Lupus

authors： Gonzalez-Suarez ML,Contreras G

更新日期：2017-10-01 00:00:00

abstract：:Previous studies in our laboratory showed a dose-dependent and hormone-specific increase in CD154 expression in T cells from females with systemic lupus erythematosus (SLE). This present study investigates if the estrogen-dependent increase in CD154 expression is due to stabilization of the messenger RNA. T cells from...

journal_title：Lupus

authors： Li X,Rider V,Kimler BF,Abdou NI

更新日期：2006-01-01 00:00:00

abstract：:XRCC1 plays a central role in mammalian DNA repair processes. Two polymorphisms of XRCC1, rs1799782 (Arg > Trp at codon 194) and rs25487 (Arg > Gln at codon 399), are common in the Han Chinese population. Our objective was to analyze the relationship between these two functional single-nucleotide polymorphisms (SNPs) ...

journal_title：Lupus

authors： Lin YJ,Wan L,Huang CM,Chen SY,Huang YC,Lai CH,Lin WY,Liu HP,Wu YS,Chen CM,Tsai YH,Tsai CH,Sheu JJ,Tsai FJ

更新日期：2009-12-01 00:00:00

abstract：:Objective The objective of this study was to describe the clinical and immunological pattern and disease outcome in Egyptian systemic lupus erythematosus patients. Patients and methods The medical records of 770 systemic lupus erythematosus patients who were followed from 2002-2015 at Kasr Alainy Hospital, Cairo Unive...

journal_title：Lupus

authors： Mahmoud GA,Shahin AA,Zayed HS,Moghazy A,Eissa BM

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Acute exercise increases IL-6, IL-10 and TNF-α levels in healthy subjects. There is no study evaluating the effect of exercise on cytokines level in systemic lupus erythematosus (SLE) patients. OBJECTIVE:Our aim was to assess IL-10, IL-6 and TNF-α levels at baseline and after acute physical exercise in pati...

journal_title：Lupus

authors： da Silva AE,dos Reis-Neto ET,da Silva NP,Sato EI

更新日期：2013-12-01 00:00:00

abstract：:Peripheral T cell apoptosis is upregulated in active SLE, in parallel with high expression of both membrane-bound and soluble (s) Fas. Previous studies postulated that sFas down-regulates apoptosis in vitro through its blockade of the Fas-L of cytotoxic cells. We have investigated the extent of apoptosis and sFas leve...

journal_title：Lupus

authors： Silvestris F,Grinello D,Tucci M,Cafforio P,Dammacco F

更新日期：2003-01-01 00:00:00

abstract：:The metabolism of radioiodinated mouse IgG was studied in mice with lupus-like syndrome before and after the onset of the disease. Before the onset of the disease, the pharmacokinetic parameters of IgG in MLR-1pr and Pristane-primed Balb/c mice were within the normal range of values. After the onset of the disease a c...

journal_title：Lupus

authors： Zhou J,Pop LM,Ghetie V

更新日期：2005-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder with multiple organ involvement. B-lymphocyte activity plays a pivotal role in the development and course of the disease. A newly developed agent called belimumab has recently been approved to treat active, autoantibody positive SLE as an add-on to st...

journal_title：Lupus

authors： Parodis I,Axelsson M,Gunnarsson I

更新日期：2013-04-01 00:00:00

abstract：:Leukopenia and anaemia are observed in about a fifth of all patients with systemic lupus erythematosus (SLE) and may be due either to the destruction of blood cells or their decreased production. The former may be humoral or cell-mediated or result from apoptosis of peripheral blood cells. Several observations suggest...

journal_title：Lupus

authors： Tiefenthaler M,Bacher N,Linert H,Mühlmann O,Hofer S,Sepp N,Amberger A,Geisen F,Obermoser G,Konwalinka G

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Many studies in adult patients with systemic lupus erythematosus (SLE) have demonstrated that myocardial dysfunction was significantly associated with enhanced disease activity. However, similar studies in paediatric patients with SLE are limited. The aim of this study was to evaluate the role of speckle tra...

journal_title：Lupus

authors： Emara M,Hafez MA,El-Bendary A,Razaky OE

更新日期：2020-10-01 00:00:00

abstract：:Diffuse alveolar hemorrhage (DAH) is a life-threatening complication of systemic lupus erythematosus (SLE). Cases complicated with DAH often have active SLE with multi-organ involvement, especially lupus nephritis. We describe a rare case of DAH as the first presenting manifestation of SLE in the absence of lupus neph...

journal_title：Lupus

authors： Al Rashidi A,Alajmi M,Hegazi MO

更新日期：2011-12-01 00:00:00

abstract：:The antiphospholipid or Hughes syndrome is the association between antiphospholipid antibodies (aPL), venous and arterial thromboses and pregnancy morbidity. Antiphospholipid syndrome (APS) commonly coexists with autoimmune diseases usually systemic lupus erythematosus (SLE), when it is known as secondary APS. When pr...

journal_title：Lupus

authors： Karim MY,Alba P,Tungekar MF,Abbs IC,Khamashta MA,Hughes GR,Hunt BJ

更新日期：2002-01-01 00:00:00

abstract：:Azathioprine-induced aplastic anemia and fatal myelosuppression is a rare occurrence in patients with systemic lupus erythematosus (SLE). We report a case of a 53-year-old female with a normal thiopurine S-methyltransferase (TPMT) level who developed aplastic anemia within 4 weeks of azathioprine initiation, resulting...

journal_title：Lupus

authors： Yeter KC,Afkhami M,Brynes RK,Quismorio FP Jr

更新日期：2013-12-01 00:00:00

abstract：:With an increasing number of international journeys occurring daily, there is also an increase in the need for appropriate medical advice for patients who will undertake such travel. In this context, the lupus patient presents a great challenge to the rheumatologist. However, the demand for such information by patient...

journal_title：Lupus

authors： Oliveira DS,Hillal JPD,Cordova DDP,de Araujo DB

更新日期：2019-12-01 00:00:00

abstract：:Vaccines have undoubtedly brought overwhelming benefits to mankind and are considered safe and effective. Nevertheless, they can occasionally stimulate autoantibody production or even a recently defined syndrome known as autoimmune/inflammatory syndrome induced by adjuvants (ASIA). There is scarce data regarding autoi...

journal_title：Lupus

authors： Perdan-Pirkmajer K,Thallinger GG,Snoj N,Čučnik S,Žigon P,Kveder T,Logar D,Praprotnik S,Tomšič M,Sodin-Semrl S,Ambrožič A

更新日期：2012-02-01 00:00:00

abstract：:Although osteoporosis has traditionally been considered a disease of women, men also incur substantial bone loss with aging, and elderly men have age-specific hip fracture incidence rates and vertebral fracture prevalence rates that are at least half those in women. Early postmenopausal bone loss (which results in the...

journal_title：Lupus

authors： Khosla S,Melton LJ 3rd,Riggs BL

更新日期：1999-01-01 00:00:00

abstract：:We report a case of bilateral choroidopathy in a 35-year-old woman with systemic lupus erythematosus (SLE) diagnosed 3 years previously, and treated with hydroxychloroquine and steroids that ceased 6 months before ocular signs. She complained about rapid bilateral blurred vision with a severe loss of visual acuity. Fl...

journal_title：Lupus

authors： Edouard S,Douat J,Sailler L,Arlet P,Astudillo L

更新日期：2011-10-01 00:00:00

abstract：:The objective of this study was to assess the prevalence, clinical, histological and immunological characteristics, and the long-term outcome of polymyositis- (PM) and dermatomyositis- (DM) associated lung disease, and to define subgroups of lung-associated inflammatory myopathies. This retrospective study included 81...

journal_title：Lupus

authors： Selva-O'Callaghan A,Labrador-Horrillo M,Muñoz-Gall X,Martínez-Gomez X,Majó-Masferrer J,Solans-Laque R,Simeon-Aznar CP,Morell-Brotard F,Vilardell-Tarrés M

更新日期：2005-01-01 00:00:00

abstract：:This is a case report on an uncommon correlation between periodic lateralized epileptiform discharges (PLEDs) and white-matter lesions in cerebral lupus, and with a reduced cerebral blood flow (CBF) in single-photon emission computed tomography (SPECT). A 47-year-old woman with a long-term history of systemic lupus er...

journal_title：Lupus

authors： Aye SM,Lim KS,Ramli NM,Tan CT

更新日期：2013-04-01 00:00:00

abstract：:Autoantibodies to DNA were discovered over 40 years ago following the discovery a few years earlier of the 'LE' cell phenomenon by Hargraves and colleagues in 1948. These investigators noted that, when leucocytes were incubated with serum from lupus patients, changes in the nucleus could be seen together with phagocyt...

journal_title：Lupus

authors： Mageed RA,Zack DJ

更新日期：2002-01-01 00:00:00

abstract：:The disease activity of patients suffering from lupus nephritis usually becomes quiescent after the onset of end stage renal failure. Reactivation of lupus activity, especially after a long period of dialysis, is uncommon. Factors that might trigger off lupus reactivation after dialysis have not been well defined. We ...

journal_title：Lupus

authors： Lui SL,Lam MF,Tse KC,Lo WK

更新日期：2002-01-01 00:00:00

abstract：:High levels of serum and/or plasma circulating DNA (cDNA) have been described in patients with systemic autoimmune diseases (SADs). However, the role of this molecule has not been clarified. Our aim was to evaluate plasma cDNA levels in 48 systemic lupus erythematosus (SLE) and 44 primary Sjögren's syndrome (SS) patie...

journal_title：Lupus

authors： Bartoloni E,Ludovini V,Alunno A,Pistola L,Bistoni O,Crinò L,Gerli R

更新日期：2011-08-01 00:00:00

abstract：:Anti-tumor necrosis factor-alpha (TNF-α) immunotherapy is currently used in the treatment of various inflammatory diseases such as rheumatoid arthritis, psoriasis, psoriatic arthritis, ankylosing spondylitis and Crohn's disease. Infliximab is a chimeric monoclonal antibody that binds to transmembrane-bound and soluble...

journal_title：Lupus

authors： Cemil BC,Atas H,Canpolat F,Akca Y,Sasmaz R

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVES:The objectives of this paper are to prospectively determine the incidence of paediatric systemic lupus erythematosus (pSLE) in Australia as well as describe the demographics, clinical presentation and one-year outcome. STUDY DESIGN:Newly diagnosed cases of pSLE were ascertained prospectively from October 20...

journal_title：Lupus

authors： Mackie FE,Kainer G,Adib N,Boros C,Elliott EJ,Fahy R,Munro J,Murray K,Rosenberg A,Wainstein B,Ziegler JB,Singh-Grewal D

更新日期：2015-01-01 00:00:00

abstract：:A 28-year-old woman with systemic lupus erythematosus (SLE) suffered recent onset fever, headache, encephalopathy followed by severe, repeated generalized seizures. Investigations revealed limbic encephalitis. Tests for Herpes simplex encephalitis and paraneoplastic encephalomyelitis were negative. High titers anti-ri...

journal_title：Lupus

authors： Stübgen JP

更新日期：1998-01-01 00:00:00