Acute myocardial infarction severity, complications, and mortality associated with lack of magnesium intake through consumption of desalinated seawater.

Abstract:

:Drinking water (DW) is an important dietary source of magnesium. Israel has recently increased desalinated seawater (DSW) production for DW, but negligible magnesium content in DSW may pose a risk of hypomagnesemia and consequential adverse cardiovascular effects. Consecutive acute myocardial infarction (AMI) patients (n = 380, age 35-75 years), hospitalized in 2015-2017 with ST-segment elevation myocardial infarction (STEMI), were divided into two groups based on their domicile region having a major supply of DSW (n = 250, 65%) or not (non-DSW; n = 130, 35%). We evaluated admission serum magnesium concentrations in patients, magnesium levels in tap water, 1-year all-cause mortality, and major adverse cardiovascular events (MACE), including all-cause mortality, nonfatal myocardial infarction, rehospitalization for heart failure or angina pectoris, stroke, coronary artery bypass grafting, and percutaneous coronary interventions. Multivariate analyses were adjusted for age and sex. Serum magnesium concentrations (mean ± SD) were significantly higher among patients in the non-DSW group compared with the DSW group (1.95 ± 0.20 mg/dL and 1.81 ± 0.20 mg/dL, P < 0.001; respectively). Additionally, the mean residential DW magnesium level in the DSW group was 5.4 ± 2.2 mg/L compared with 25.1 ± 3.4 mg/L, P < 0.01 in the non-DSW group. Fewer patients (although not statistically significant) in the non-DSW group experienced major adverse cardiovascular events (MACE) or 1-year-all-cause mortality compared with the patients in the DSW group (12.4% and 20%, P = 0.065; respectively). In conclusion, in post AMI patients, we found nonsignificant higher MACE and 1-year mortality with the use of DSW.

journal_name

Magnes Res

journal_title

Magnesium research

authors

Shlezinger M,Amitai Y,Goldenberg I,Atar S,Shechter M

doi

10.1684/mrh.2019.0449

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

39-50

issue

2

eissn

0953-1424

issn

1952-4021

pii

mrh.2019.0449

journal_volume

32

pub_type

杂志文章
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    authors: Kurita T

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    authors: Michailova A,McCulloch AD

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    authors: Kenney MA,McCoy H

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    doi:

    authors: Fleckenstein-Grün G,Matyas S,Dumont L

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  • Association between low serum magnesium concentration and hyperuricemia.

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    更新日期:2015-06-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Howarth FC,Singh J,Waring JJ,Hustler BI,Bailey M

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  • Bone histomorphometry of ovariectomized or orchiectomized rats fed a moderately magnesium-deficient fructose diet and treated with exogenous oestrogen or testosterone.

    abstract::To investigate the effects of sex hormones on bone histomorphometry, and bone density (BMD), 10 week old ovariectomized (OVX), orchiectomized (ORX), and sham-operated (SHAM) rats fed a moderately magnesium-deficient fructose diet were studied. One third of the OVX and ORX rats were injected with beta-oestradiol-3-benz...

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    pub_type: 杂志文章

    doi:

    authors: Koh ET,Yeh JK,Bourdeau JE,Chen MM,Om AS

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    pub_type: 杂志文章,评审

    doi:

    authors: Zeana CD

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    pub_type: 杂志文章

    doi:

    authors: Hughes MS,Crow DR,Birch NJ

    更新日期:1992-06-01 00:00:00

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    doi:

    authors: Scheibe F,Haupt H,Ising H,Cherny L

    更新日期:2002-03-01 00:00:00

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    doi:

    authors: Nishio A,Ishiguro S,Ikegaki I,Matsumoto S,Yoshimitsu F,Miyazaki A

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    pub_type: 杂志文章,评审

    doi:

    authors: Billard JM

    更新日期:2006-09-01 00:00:00

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    authors: Korycińska A,Dabrowski W,Rzecki Z,Dragan M,Pozarowski P,Wrońska J,Stazka J,Pasternak K,Roliński J

    更新日期:2005-12-01 00:00:00

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    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Lukácsi L,Lintner F,Gimes G,Zsolnai B,Somogyi J

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  • Magnesium and selected parameters of the non-enzymatic antioxidant and immune systems and oxidative stress intensity in the seminal plasma of fertile males.

    abstract:INTRODUCTION:The present study investigated associations between environmental exposure to magnesium (Mg) and the levels of oxidative stress parameters and selected cytokines, and the antioxidant defense system in the seminal plasma of fertile males. MATERIALS AND METHODS:The study population consisted of 57 healthy, ...

    journal_title:Magnesium research

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    doi:10.1684/mrh.2015.0377

    authors: Kasperczyk A,Dobrakowski M,Zalejska-Fiolka J,Horak S,Birkner E

    更新日期:2015-01-01 00:00:00

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    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Iezhitsa IN,Onishchenko NV,Churbakova NV,Parshev VV,Petrov VI,Spasov AA

    更新日期:2002-12-01 00:00:00

  • Triamterene may preserve lymphocyte magnesium and potassium in patients with congestive heart failure.

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    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

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  • Correlations between feeding type and blood ionized magnesium levels in Japanese preterm infants.

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    pub_type: 杂志文章

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    journal_title:Magnesium research

    pub_type: 杂志文章,随机对照试验

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    authors: Messeha MM,Boshra V

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    doi:

    authors: Rondón LJ,Rayssiguier Y,Mazur A

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    pub_type: 杂志文章

    doi:10.1684/mrh.2010.0198

    authors: Rosanoff A

    更新日期:2010-03-01 00:00:00

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    doi:

    authors: Pakfetrat M,Malekmakan L,Roozbeh J,Haghpanah S

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  • Magnesium deficiency reduces fear-induced conditional lick suppression in mice.

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    pub_type: 杂志文章

    doi:

    authors: Bardgett ME,Schultheis PJ,Muzny A,Riddle MD,Wagge JR

    更新日期:2007-03-01 00:00:00

  • Magnesium and the inflammatory response: potential pathophysiological implications in the management of patients with aneurysmal subarachnoid hemorrhage?

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    pub_type: 临床试验,杂志文章

    doi:

    authors: Muroi C,Burkhardt JK,Hugelshofer M,Seule M,Mishima K,Keller E

    更新日期:2012-07-01 00:00:00

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    pub_type: 杂志文章,评审

    doi:

    authors: Durlach J,Durlach V,Rayssiguier Y,Ricquier D,Goubern M,Bertin R,Bara M,Guiet-Bara A,Olive G,Mettey R

    更新日期:1991-09-01 00:00:00

  • Angiotensin converting enzyme inhibitors, thiazide diuretics and magnesium balance. A preliminary study.

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    pub_type: 杂志文章

    doi:

    authors: Malini PL,Strocchi E,Valtancoli G,Ambrosioni E

    更新日期:1990-09-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Pasternak K,Kiełczykowska M,Sztanke M,Borzecki A

    更新日期:2003-06-01 00:00:00