Abstract:
:Nanoparticles have gained ground in several fields. However, it is important to consider their potentially hazardous effects on humans, flora, and fauna. Human exposure to nanomaterials can occur unintentionally in daily life or in industrial settings, and the continuous exposure of the biological components (cells, receptors, proteins, etc.) of the immune system to these particles can trigger an unwanted immune response (activation or suppression). Here, we present different studies that have been carried out to evaluate the response of immune cells in the presence of nanoparticles and their possible applications in the biomedical field.
journal_name
Curr Pharm Desjournal_title
Current pharmaceutical designauthors
Mitarotonda R,Giorgi E,Desimone MF,De Marzi MCdoi
10.2174/1381612825666190926161209subject
Has Abstractpub_date
2019-01-01 00:00:00pages
3960-3982issue
37eissn
1381-6128issn
1873-4286pii
CPD-EPUB-101044journal_volume
25pub_type
杂志文章,评审abstract::The beneficial effect of antihypertensive treatment on the risk of major vascular events is well established. Several trials comparing older and newer drugs in the treatment of primary hypertension suggested that it is the blood pressure achieved, rather than choice of the drug that determines most of the primary outc...
journal_title:Current pharmaceutical design
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journal_title:Current pharmaceutical design
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journal_title:Current pharmaceutical design
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journal_title:Current pharmaceutical design
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journal_title:Current pharmaceutical design
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journal_title:Current pharmaceutical design
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journal_title:Current pharmaceutical design
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journal_title:Current pharmaceutical design
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abstract::Over the last several years, it has become increasingly clear that dendritic cells (DC) are not only critical for the initiation of T cell immunity, but these cells also determine the course of the subsequent immune response (i.e. tolerance vs. immunity, Th1 vs. Th2). However, the mechanisms by which DC can influence ...
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journal_title:Current pharmaceutical design
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journal_title:Current pharmaceutical design
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doi:10.2174/1381612826666200701151403
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journal_title:Current pharmaceutical design
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abstract::The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a cAMP-regulated Cl- channel whose major function is to facilitate epithelial fluid secretion. Loss-of-function mutations in CFTR cause the genetic disease cystic fibrosis. CFTR is required for transepithelial fluid transport in certain secretor...
journal_title:Current pharmaceutical design
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更新日期:2015-01-01 00:00:00
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