Abstract:
Background:Functional abdominal pain disorders (FAPD) are prevalent in the paediatric population, however, there is currently no consensus regarding best practices for treatment. The use of probiotics is becoming popular to treat FAPD. The goal of this rapid review is to synthesize the best evidence on the use of probiotics in children with FAPD. Methods:Searches were conducted on five main databases. Randomized controlled trials (RCTs) of probiotic use in children (0 to 18 years) with FAPD were searched. Populations of interest were patients with functional abdominal pain (FAP), irritable bowel syndrome (IBS), and functional dyspepsia (FD), recruited based on Rome criteria. Outcomes of interest were changes in abdominal pain severity, frequency, and duration. Findings:Eleven RCTs with 829 participants with the diagnosis of FAP (n=400), IBS (n=329), FD (n=45), and mixed population (n=55) were included. Of six studies of children with FAP, two (n=103) used Lactobacillus rhamnosus GG (LGG) and reported no significant effects on pain, and four (n=281) used Lactobacillus (L) reuteri DSM 17938, of which three (n=229) reported significant positive effects on either severity or frequency of pain. Of six trials of children with IBS, four (n=219) used LGG, of which three (n=168) reported a positive effect. One (n=48) used bifidobacteria and one used VSL #3 (n=59), both demonstrating positive effects with probiotics. Two studies of FD reported no benefit. No adverse events were attributed to probiotics. Conclusions:There is preliminary evidence for use of probiotics, particularly LGG, in reducing abdominal pain in children with IBS. There are inconsistent positive effects of other probiotics, including L. reuteri DSM 17938, in reducing pain in patients with FAP, IBS, or FD. More RCTs with rigorous methodology using single or combination probiotics are warranted.
journal_name
Paediatr Child Healthjournal_title
Paediatrics & child healthauthors
Ding FCL,Karkhaneh M,Zorzela L,Jou H,Vohra Sdoi
10.1093/pch/pxz036subject
Has Abstractpub_date
2019-09-01 00:00:00pages
383-394issue
6eissn
1205-7088issn
1918-1485pii
pxz036journal_volume
24pub_type
杂志文章,评审abstract:OBJECTIVE:To explore the factors associated with the sex disparity showing a greater prevalence of obesity/overweight in boys compared with girls in Chinese school children. METHODS:Sampled students and their parents were asked to complete a questionnaire. Perceptions of weight status by the parents, grandparents and ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/19.7.e113
更新日期:2014-08-01 00:00:00
abstract::Recreation, globalization, migration, and families visiting friends and relatives (VFRs) overseas have increased the frequency of international travel and potential exposures to tropical diseases. Young infected patients can present a diagnostic challenge to clinicians when they return to Canada, with significant cons...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxy138
更新日期:2018-12-01 00:00:00
abstract::Idiopathic neonatal priapism is a rare and poorly understood phenomenon. The case of an otherwise healthy premature male newborn who was noted to have a persistent penile erection on the first day of life is presented. A Doppler ultrasound of the penis was performed, along with the first-ever cavernous blood gas analy...
journal_title:Paediatrics & child health
pub_type:
doi:10.1093/pch/16.1.e6
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Despite the important role of drug therapy in children, there is often a lack of readily available information regarding the indications and dosing regimens for medications in paediatrics. OBJECTIVE:To collect data on where family physicians obtain this prescribing information. METHOD:A structured question...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/8.4.219
更新日期:2003-04-01 00:00:00
abstract::In the present longitudinal study, the physical growth and health of 36 early-deprived postinstitutionalized Romanian orphans (ROs; 17 boys) adopted by Canadian families are documented. Data were collected for each child at three time points: at 11 months postadoption, at 4.5 years of age and at 10.5 years of age. Dat...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:To describe an approach to history, physical examination and investigation for the developmentally delayed child. METHODS:A review of electronic databases from 1997 to 2001 was done searching for articles relating to the approach to or investigations of children with developmental delay. Five studies, includ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/8.1.16
更新日期:2003-01-01 00:00:00
abstract::While terms such as 'essential' and 'nonessential' used amidst the COVID-19 pandemic may serve a practical purpose, they also pose a risk of obstructing our view of the harmful indirect health consequences of this crisis. SARS-CoV-2 cases and deaths in children are minimal compared to adults, but the pandemic impacts ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxaa077
更新日期:2020-08-01 00:00:00
abstract:Introduction:In June 2012, the government of Canada severely restricted the scope of the Interim Federal Health Program that had hitherto provided coverage for the health care needs of refugee claimants. The Quebec government decided to supplement coverage via the provincial health program. Despite this, we hypothesize...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxx115
更新日期:2017-11-01 00:00:00
abstract:Background:Referrals to paediatric endocrine clinics for short stature are common. Height velocity (HV) is an essential component of the evaluation of short stature as growth deceleration often reflects an underlying paediatric endocrine diagnosis (PED). Access to previous measurements facilitates prompt calculation of...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxy079
更新日期:2019-05-01 00:00:00
abstract::There have been publically expressed concerns about the costs and allocation of neonatal and perinatal health care resources in Canada and elsewhere for the past 15 years. This paper reports information from a symposium held during the 1996 Canadian Paediatric Society (CPS) annual meeting sponsored by the CPS Section ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/4.1.51
更新日期:1999-01-01 00:00:00
abstract::Parents of children with type 1 diabetes commonly worry about the ability of school personnel to respond to their child's diabetes needs, and may feel anxious about the health, safety and inclusion of their child in school. Physicians may be confronted by parents' fears, anxieties and apprehension, and need to know ho...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/10.1.25
更新日期:2005-01-01 00:00:00
abstract::Disability is a major public health concern worldwide and the situation for children with disabilities is even more serious. The present article will focus on the issue of children with disabilities in low-income countries. Approximately one-third of the world's disabled population is children and many of these disabl...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/10.5.269
更新日期:2005-05-01 00:00:00
abstract::Respiratory syncytial virus (RSV) is recognized as an important cause of childhood morbidity and mortality. Vaccine development has been challenging in young infants and has required the advent of molecular technologies to optimize the safety profile, while maintaining immunogenicity of live-attenuated vaccines. Prote...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/8.10.605
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:The importance of the teaching role of residents in medical education is increasingly being recognized. There are little data about how this role is perceived within training programs or how residents develop their teaching skills. The aims of the present study were to explore the perspectives of Canadian pa...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/13.8.675
更新日期:2008-10-01 00:00:00
abstract::There is a growing focus in the medical community on de-escalating medical treatments where appropriate; however, specific efforts to reduce medication burden in patients with polypharmacy has largely been targeted toward adult populations. Polypharmacy increases the risk of adverse drug reactions in children, and tha...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxy188
更新日期:2019-08-01 00:00:00
abstract::[This corrects the article on p. 583 in vol. 12.][This corrects the article on p. 591 in vol. 12.]. ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/12.10.858
更新日期:2007-12-01 00:00:00
abstract::This practice point summarizes the use of antiviral drugs to manage influenza illness in children and youth for the 2012/2013 season. It excerpts a recently published, full-length update of Canadian recommendations for clinicians on the use of antiviral drugs for the prevention and treatment of influenza, with a focus...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:
更新日期:2013-03-01 00:00:00
abstract::In the past three decades, rapidly changing demographic characteristics have been witnessed in western society. Concurrently, numerous culture-related studies have attested to the disparity in health services among different ethnic groups. Reports have shown contributing factors that can render main stream services in...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/9.9.627
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:A checklist that promotes compliance with aseptic technique during line insertion is a component of many care bundles aimed at reducing nosocomial infections among intensive care unit patients. OBJECTIVE:To determine whether the use of bundled interventions that include a checklist during central-line inser...
journal_title:Paediatrics & child health
pub_type: 杂志文章,评审
doi:10.1093/pch/19.4.e20
更新日期:2014-04-01 00:00:00
abstract::Details of an innovative model for providing health education to families and patients using a coordinated series of skill-based educational opportunities are described. The model offers a variety of educational courses for parents of children at each developmental stage. Each course provides transferable skills that ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/5.6.329
更新日期:2000-09-01 00:00:00
abstract::The rate of multiple pregnancy has increased in developed countries, a finding usually attributed to more widespread use of assisted reproductive technologies. Multiple pregnancies are associated with a greater risk of pregnancy complications, including intrauterine growth restriction of one or more of the fetuses, va...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/11.5.283
更新日期:2006-05-01 00:00:00
abstract:Objective:To evaluate the relative incidence of cardiogenic and septic shock in term neonates and identify findings that help differentiate the two entities. Study Design:We conducted a retrospective chart review of term neonates presenting to British Columbia Children's Hospital (BCCH) with decompensated shock of an ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxz078
更新日期:2019-06-24 00:00:00
abstract::Arthropod-borne diseases do not occur commonly in Canada. Nevertheless, Canadians run the risk of contracting certain infections within the country during arthropod season, as well as when travelling abroad. Therefore, it is important that clinicians are aware of the possible occurrence of arthropod-borne diseases, an...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/5.4.206
更新日期:2000-05-01 00:00:00
abstract::Nontyphoidal Salmonella (NTS) infections are primarily transmitted by contaminated food or water or contact with carrier animals (particularly reptiles), and present with diarrhea. Antibiotics do not decrease the severity or duration of diarrhea and may increase the incidence of NTS carriage, so they should only be us...
journal_title:Paediatrics & child health
pub_type: 杂志文章,评审
doi:10.1093/pch/pxy199
更新日期:2019-02-01 00:00:00
abstract::The present article is intended to inform paediatricians about the associations between ambient air pollution and adverse health outcomes in children within the context of current epidemiological evidence.The majority of the current literature pertains to adverse respiratory health outcomes, including asthma, other re...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:
更新日期:2006-10-01 00:00:00
abstract::Sepsis is a systemic inflammatory response to suspected or proven infection. Given its importance in terms of morbidity and mortality, a number of initiatives by several professional societies in recent years have led to the development of guidelines for the recognition and timely management of sepsis. The principal e...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxz178
更新日期:2020-11-02 00:00:00
abstract::Acute otitis media (AOM) continues to be a common infection in young children. Milder disease, usually due to viruses or less virulent bacteria, resolves equally quickly with or without antibiotics. A bulging tympanic membrane, especially if yellow or hemorrhagic, has a high sensitivity for AOM that is likely to be ba...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/21.1.39
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To identify a target group of children with acute immune thrombocytopenic purpura (ITP) that may not require hospitalization for management. METHODS:A retrospective chart review was conducted of all children admitted over a two-year period to a tertiary care paediatric hospital with the diagnosis of acute IT...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/7.6.386
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:Health care professionals (HCPs) may be involved in counselling women after an antenatal diagnosis of various fetal anomalies. Many pregnant women consider termination of pregnancy (TOP) after antenatal diagnosis of various fetal anomalies. Little is known, however, about the attitudes of HCPs regarding TOP ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/17.8.e86
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Current recommendations suggest that routine screening for hypoglycemia should be performed in all term newborns with a birth weight (BW) below the 10th percentile. The impact of updated growth curves on the incidence of hypoglycemia in small-for-gestational-age (SGA) newborns has not been evaluated. OBJECT...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/15.5.271
更新日期:2010-05-01 00:00:00