Post-mortem CT: is coronary angiography required in the presence of a high coronary artery calcium score?

Abstract:

AIM:To test whether a high coronary artery score predicts that the subsequent post-mortem computed tomography (PMCT) with angiography (PMCTA) will diagnose significant coronary artery disease (CAD); to test the diagnostic impact of assuming there is significant CAD based on a high coronary artery calcium (CAC) score alone; and (3) to test whether the clinical CAC score threshold (400) is the most accurate to make this prediction. MATERIALS AND METHODS:CAC scoring and PMCTA were performed in cases of adult sudden natural death. Angiography was reviewed to determine if there was sufficient CAD to give as the cause of death. Data were analysed to test whether high calcium score predicts significant CAD. RESULTS:PMCTA with CAC score was successful in 100/104 PMCT examinations and in 87/100 angiography examinations (87%). Forty-six cases (46%) had a CAC score of >400, the clinical level of severe disease. CAD was given as the cause of death in 31 (67%) of these cases. Angiography was successful in 39 of these cases (84.7%) and showed severe CAD in all but one (97%). Twenty-five (25%) cases were diagnosed with a CAD death without a high CAC score. CONCLUSION:Although CAC score can neither diagnose nor exclude death due to CAD, the addition of angiography adds little diagnostic information to a high CAC score. If PMCT investigation is to exclude trauma and provide a medical cause of death on the "balance of probabilities", angiography is not required when the calcium score >400. This could reduce the number of patients requiring angiography by almost 50%.

journal_name

Clin Radiol

journal_title

Clinical radiology

authors

Robinson C,Deshpande A,Rutty G,Morgan B

doi

10.1016/j.crad.2019.06.034

subject

Has Abstract

pub_date

2019-12-01 00:00:00

pages

926-932

issue

12

eissn

0009-9260

issn

1365-229X

pii

S0009-9260(19)30374-5

journal_volume

74

pub_type

杂志文章
  • Low dose low osmolar intravenous urography.

    abstract::A prospective double blind randomised trial using 25 ml of Hexabrix 320 (ioxaglate, May and Baker), Niopam 370 (iopamidol, Merck) or Omnipaque 350 (iohexol, Nycomed) intravenous urography was carried out. The results showed no perceptible difference in the diagnostic quality of urograms with each of the media. An addi...

    journal_title:Clinical radiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0009-9260(87)80239-8

    authors: Eyes BE,Goldman M,Nixon TE,Scally J,Brown A

    更新日期:1987-07-01 00:00:00

  • Acute transient radiation hepatitis following whole abdominal irradiation.

    abstract::Sporadic cases or radiation hepatitis have been reported following doses above 3500 rad delivered in 3-4 weeks to the liver. The authors report their experience of radiation hepatitis in two out of 117 consecutive lymphoma cases treated with total abdominal irradiation. These two patients developed clinically overt ma...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(76)80107-9

    authors: Kim TH,Panahon AM,Friedman M,Webster JH

    更新日期:1976-10-01 00:00:00

  • Intratumor gas--an ultrasound sign of tumour necrosis.

    abstract::The ultrasound appearances of primary liver tumour in three patients are described. Changes in these appearances following devascularisation of the tumour by transcatheter embolisation are demonstrated. A possible mechanism for the change in appearances is suggested and is discussed in the light of plain radiographic ...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(80)80028-6

    authors: Dubbins P,Nunnerley HB

    更新日期:1980-11-01 00:00:00

  • Retrospective analysis of technical success rate and procedure-related complications of 867 percutaneous CT-guided needle biopsies of lung lesions.

    abstract:AIM:To investigate the technical success rate and procedure-related complications of computed tomography (CT)-guided needle biopsy of lung lesions and to identify the factors that are correlated with the occurrence of procedure-related complications. MATERIALS AND METHODS:This was a single- institution retrospective s...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2017.07.023

    authors: Mills M,Choi J,El-Haddad G,Sweeney J,Biebel B,Robinson L,Antonia S,Kumar A,Kis B

    更新日期:2017-12-01 00:00:00

  • An unusual angiogram in a patient with gastrointestinal bleeding.

    abstract::A patient presenting with upper gastrointestinal bleeding had two visceral angiograms, the second of which demonstrated the hepatic veins in the late phase of the hepatic arterial injection. This observation led to the correct diagnosis of hepatic telangiectasia with arteriovenous shunting and the suspicion, subsequen...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(05)80607-5

    authors: Sackier JM,Dawson P,Allison D,Spencer J

    更新日期:1990-06-01 00:00:00

  • NHSBSP type 1 interval cancers: a scientifically valid grouping?

    abstract:AIM:To assess whether there are differences in the pathological features or survival between the new National Health Service Breast Screening Programme (NHSBSP) interval cancer classification system category of type 1 interval cancers, and the previously used, separate categories of occult, unclassified, and true inter...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2006.10.002

    authors: Porter GJ,Evans AJ,Burrell HC,Lee AH,Chakrabarti J

    更新日期:2007-03-01 00:00:00

  • An assessment of Ultrasound screening for soft tissue lumps referred from primary care.

    abstract:AIMS:To assess the efficacy of ultrasound as a screening tool in the assessment of soft-tissue masses referred from primary care and to investigate the incidence of malignancy in this population. MATERIALS AND METHODS:Retrospective analysis was performed on patients who underwent ultrasound for a suspected soft-tissue...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2018.07.102

    authors: Charnock M,Kotnis N,Fernando M,Wilkinson V

    更新日期:2018-12-01 00:00:00

  • Ultrasound of the pleura: an assessment of its clinical value.

    abstract::In a prospective study, A mode ultrasound scanning contributed to the diagnosis and management of 24 of 50 consecutive patients with pleural disease. In 30% of patients it was superior to radiology in clarifying the solid or fluid nature of a pleural opacity, and in 42% of patients it allowed selection of the most app...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(81)80042-6

    authors: Lipscomb DJ,Flower CD,Hadfield JW

    更新日期:1981-05-01 00:00:00

  • Immediate and long-term CT appearances following radiofrequency ablation of renal tumours.

    abstract::The incidence of renal cell carcinoma is increasing and image-guided radiofrequency ablation (RFA) is emerging as a safe and effective primary treatment. Therefore, it is essential for radiologists to appreciate the varied computed tomography (CT) imaging features following RFA. Prompt recognition of residual or recur...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.crad.2007.07.002

    authors: Rutherford EE,Cast JE,Breen DJ

    更新日期:2008-02-01 00:00:00

  • Reasons underlying negative mammography in patients with palpable breast cancer.

    abstract::It is well recognized that a negative mammogram report does not exclude the presence of breast carcinoma. This study examines the accuracy of mammography in patients with palpable breast cancer. In particular, the study evaluates the reasons underlying negative mammography in breast cancer. All patients with Paget's d...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(05)83454-3

    authors: Coveney EC,Geraghty JG,O'Laoide R,Hourihane JB,O'Higgins NJ

    更新日期:1994-02-01 00:00:00

  • Sonographic demonstration of septicaemia with gas-forming organisms after liver transplantation.

    abstract::Sepsis with gas-forming organisms, e.g. Clostridium perfringens and anaerobic streptococci occurred in three of 120 liver-transplant recipients (2.5%). The diagnosis was made in all three patients by bedside ultrasound, before blood cultures revealed bacterial growth. Floating high amplitude echoes within the extra- a...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(05)80568-9

    authors: Jantsch H,Barton P,Függer R,Lechner G,Graninger W,Waneck R,Winkler M

    更新日期:1991-06-01 00:00:00

  • Radiomic mapping model for prediction of Ki-67 expression in adrenocortical carcinoma.

    abstract:AIM:To determine the value of contrast-enhanced computed tomography (CT)-derived radiomic features in the preoperative prediction of Ki-67 expression in adrenocortical carcinoma (ACC) and to detect significant associations between radiomic features and Ki-67 expression in ACC. MATERIALS AND METHODS:For this retrospect...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2020.01.012

    authors: Ahmed AA,Elmohr MM,Fuentes D,Habra MA,Fisher SB,Perrier ND,Zhang M,Elsayes KM

    更新日期:2020-06-01 00:00:00

  • The clinical importance of axillary lymphadenopathy detected on screening mammography.

    abstract::The aim of this study was to determine the incidence and cause of axillary lymphadenopathy detected by screening mammography and to devise a management protocol for this pathology. In a retrospective study of 95,806 consecutive screening mammograms, 37 cases of 'pathological' axillary nodes were identified using two o...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(97)80008-6

    authors: Murray ME,Given-Wilson RM

    更新日期:1997-06-01 00:00:00

  • Sclerotic changes of the sternal end of the clavicle.

    abstract::Five adult females with swelling, tenderness and similar sclerotic changes of the sternal end of the clavicle are presented. They were recognised during a 10-year period, suggesting that the condition is rare and may be misdiagnosed. In three patients strain of the sternoclavicular joint seemed to be an aetiological f...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(85)80010-6

    authors: Jurik AG,De Carvalho A,Graudal H

    更新日期:1985-01-01 00:00:00

  • The effect of angiographic technique and image quality on the reproducibility of measurement of carotid stenosis and assessment of plaque surface morphology.

    abstract::We studied the reproducibility of measurement of carotid stenosis and assessment of plaque surface morphology on 1001 angiograms from a consecutive series of patients entered into the European Carotid Surgery Trial. Inter-observer agreement (Kappa statistic, 95% confidence interval (CI)) for categorization of carotid ...

    journal_title:Clinical radiology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1016/s0009-9260(98)80273-0

    authors: Rothwell PM,Gibson RJ,Villagra R,Sellar R,Warlow CP

    更新日期:1998-06-01 00:00:00

  • Imaging of the aortic valve with MRI and CT angiography.

    abstract::The aortic valve may be affected by a wide range of congenital and acquired diseases. Echocardiography is the main non-invasive imaging technique for assessing patho-anatomical alterations of the aortic valve and adjacent structures and in many cases is sufficient to establish a diagnosis and/or guide treatment decisi...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.crad.2013.07.014

    authors: Harvey JJ,Hoey ET,Ganeshan A

    更新日期:2013-12-01 00:00:00

  • Combining low tube voltage and iterative reconstruction for contrast-enhanced CT imaging of the chest-initial clinical experience.

    abstract:AIM:To evaluate the image quality of contrast-enhanced chest computed tomography (CT) with low tube voltage settings using an iterative reconstruction algorithm (iDose4) and standard dose filtered back projection (FBP) CT in patients with normal body mass index (BMI). MATERIALS AND METHODS:Eighty patients with normal ...

    journal_title:Clinical radiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.crad.2012.12.009

    authors: Li Q,Yu H,Zhang L,Fan L,Liu SY

    更新日期:2013-05-01 00:00:00

  • The role of imaging in the evaluation of parotid disease.

    abstract::In this review the imaging features of a range of parotid lesions are presented and the roles of ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) in the assessment of parotid disease are discussed. ...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审

    doi:10.1053/crad.2001.0865

    authors: Howlett DC,Kesse KW,Hughes DV,Sallomi DF

    更新日期:2002-08-01 00:00:00

  • There's a hole in my symphysis -- a review of disorders causing widening, erosion, and destruction of the symphysis pubis.

    abstract::The symphysis pubis is demonstrated on many conventional radiographic and cross-sectional examinations and abnormality of the symphysis pubis is a common imaging finding with numerous possible causes. Many significant disorders that affect the symphysis pubis cause it to appear widened, eroded, or destroyed on imaging...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.crad.2012.03.021

    authors: Budak MJ,Oliver TB

    更新日期:2013-02-01 00:00:00

  • Is there an association between mesenteric panniculitis and lymphoma? A case control analysis.

    abstract:AIM:To determine the prevalence and association of mesenteric panniculitis (MP) in a group of patients with non-Hodgkin's lymphoma (NHL) compared to control group. MATERIALS AND METHODS:We retrospectively evaluated computed tomography (CT) and combined positron-emission tomography (PET) with CT examinations of a total...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2017.05.008

    authors: Khasminsky V,Ram E,Atar E,Steinminz A,Issa N,Bachar GN

    更新日期:2017-10-01 00:00:00

  • Postoperative CT in pancreas transplantation.

    abstract:AIM:To examine the usage and value of computed tomography (CT) following simultaneous pancreas and kidney (SPK) transplantation. MATERIALS AND METHODS:Indications for postoperative CT, key findings, and their influence on management were determined by retrospective analysis. RESULTS:Ninety-eight patients underwent 31...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2015.06.086

    authors: Powell FE,Harper SJ,Callaghan CJ,Shaw A,Godfrey EM,Bradley JA,Watson CJ,Pettigrew GJ

    更新日期:2015-11-01 00:00:00

  • Direct comparison of Neuroform and Enterprise stents in the treatment of wide-necked intracranial aneurysms.

    abstract:AIM:To compare the complications and outcomes of Neuroform and Enterprise stents in the treatment of unruptured wide-necked aneurysms. MATERIALS AND METHODS:Under the auspices of the institutional review board, a review of a prospectively collected patient log identified 130 patients who underwent elective stent-assis...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2014.07.015

    authors: Durst CR,Khan P,Gaughen J,Patrie J,Starke RM,Conant P,Liu KC,Jensen ME,Evans AJ

    更新日期:2014-12-01 00:00:00

  • Case report: obstructive jaundice secondary to an intussuscepting duodenal villous adenoma.

    abstract::Small intestinal tumours are rare, forming 1% of all gastrointestinal tumours; most occur in the duodenum. Villous adenomas form only a very small proportion of the duodenal tumours. They usually occur in the periampullary region and show a marked propensity for malignant change. The usual mode of presentation is with...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(05)80040-6

    authors: Vinnicombe S,Grundy A

    更新日期:1992-07-01 00:00:00

  • Marrow outside marrow: imaging of extramedullary haematopoiesis.

    abstract::Extramedullary haematopoiesis (EMH) refers to the formation of non-neoplastic blood cell lines outside the bone marrow and is a common incidental finding when patients with haematological disorders are imaged. EMH presenting as mass (tumefactive EMH) has long been a radiological conundrum as it resembles neoplasms. Se...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.crad.2019.12.016

    authors: Malla S,Razik A,Das CJ,Naranje P,Kandasamy D,Kumar R

    更新日期:2020-08-01 00:00:00

  • 3D CT cerebral angiography technique using a 320-detector machine with a time-density curve and low contrast medium volume: comparison with fixed time delay technique.

    abstract:AIM:To describe a cerebral computed tomography angiography (CTA) technique using a 320-detector CT machine and a small contrast medium volume (35 ml, 15 ml for test bolus). Also, to compare the quality of these images with that of the images acquired using a larger contrast medium volume (90 or 120 ml) and a fixed time...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2013.10.021

    authors: Das K,Biswas S,Roughley S,Bhojak M,Niven S

    更新日期:2014-03-01 00:00:00

  • Correlations between the mammographic features of ductal carcinoma in situ (DCIS) and C-erbB-2 oncogene expression. Nottingham Breast Team.

    abstract:PURPOSE:C-erbB-2 oncogene expression is found in 60% of DCIS cases. C-erbB-2 expression in DCIS has been shown to correlate with comedo subtype, large cell size, lymphoid infiltrate, nuclear pleomorphism, multinucleation and high mitotic rate. These findings have led to the suggestion that the subgroup of DCIS that exp...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(05)82937-x

    authors: Evans AJ,Pinder SE,Ellis IO,Sibbering DM,Elston CW,Poller DN,Wilson AR

    更新日期:1994-08-01 00:00:00

  • Tumour progression or pseudoprogression? A review of post-treatment radiological appearances of glioblastoma.

    abstract::Glioblastoma (GBM) is a common brain tumour in adults, which, despite multimodality treatment, has a poor median survival. Efficacy of therapy is assessed by clinical examination and magnetic resonance imaging (MRI) features. There is now a recognised subset of treated patients with imaging features that indicate "pro...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.crad.2015.06.096

    authors: Abdulla S,Saada J,Johnson G,Jefferies S,Ajithkumar T

    更新日期:2015-11-01 00:00:00

  • Spleen phenotype in autosomal dominant polycystic kidney disease.

    abstract:AIM:To evaluate splenic phenotype in autosomal dominant polycystic kidney disease (ADPKD) including presence of cysts and splenomegaly to determine if these are ADPKD related or represent unrelated incidental findings. MATERIALS AND METHODS:The axial/coronal T2-weighted images of ADPKD patients (n=215) and age/gender-...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2019.08.015

    authors: Yin X,Prince WK,Blumenfeld JD,Zhang W,Donahue S,Bobb WO,Rennert H,Askin G,Barash I,Prince MR

    更新日期:2019-12-01 00:00:00

  • The significance of colonic mucosal lymphoid hyperplasia and aphthoid ulcers in Crohn's disease.

    abstract:OBJECTIVE:To access concordance between radiological severity of aphthae and the more advanced features of Crohn's disease. PATIENTS AND METHODS:In 75 patients with an established diagnosis of Crohn's disease, we evaluated the radiological severity of colonic aphthae by meticulous double-contrast radiography. The degr...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(96)80243-1

    authors: Hizawa K,Iida M,Aoyagi K,Fujishima M

    更新日期:1996-10-01 00:00:00

  • Renal adenomas.

    abstract::In presenting five new cases of renal adenomas the authors describe the general nature of these rare tumours. If the small adenoma corresponding to microscopic forms is frequent, the large adenoma is rare and always solitary. Haematuria and pain are the most common signs. The classic criterion of non-malignancy in a s...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(79)80100-2

    authors: Bruneton JN,Ballanger P,Ballanger R,Delorme G

    更新日期:1979-05-01 00:00:00