Reliability of colour perimetry to assess macular pigment optical density in age-related macular degeneration.

Abstract:

BACKGROUND:The aim of this study was to determine the intra-session repeatability and inter-examiner reproducibility of the colour perimetry technique when assessing in vivo macular pigment optical density in age-related macular degeneration patients. METHODS:Age-related macular degeneration patients were classified into four groups: early age-related macular degeneration, intermediate age-related macular degeneration, atrophic age-related macular degeneration and neovascular age-related macular degeneration after undergoing fundus photography (TRC 50DX type IA) and spectral-domain optical coherence tomography analysis (Topcon 3D-2000). Central fixation was confirmed in all patients using the MP-1 microperimeter (Nidek, Padua, Italy). To analyse repeatability, one examiner obtained three consecutive macular pigment optical density measures with MonCV3 device (Metrovision, Perenchies, France). To study agreement between two observers, a second examiner performed another macular pigment optical density measurement in random order. Within-subject standard deviation, coefficient of variation, and intraclass correlation coefficient data were obtained. RESULTS:Fifty two (32 females and 20 males) consecutive age-related macular degeneration patients having a mean age of 71.5 ± 8.2 years were recruited. Six had early age-related macular degeneration, 25 had intermediate age-related macular degeneration, 10 had atrophic age-related macular degeneration and 11 had neovascular age-related macular degeneration. For repeatability, coefficient of variation values ranged from 22.3% (neovascular age-related macular degeneration) to 41.0% (atrophic age-related macular degeneration) and intraclass correlation coefficient values from 0.52 (intermediate age-related macular degeneration) to 0.79 (neovascular age-related macular degeneration). For agreement between two examiners, coefficient of variation values ranged from 20.1% (intermediate age-related macular degeneration) to 37.8% (neovascular age-related macular degeneration) and intraclass correlation coefficient values from 0.61 (neovascular age-related macular degeneration) to 0.80 (atrophic age-related macular degeneration). CONCLUSION:The reliability (intra-session repeatability and inter-examiner reproducibility) of colour perimetry technique to assess macular pigment optical density in age-related macular degeneration patients is only moderate. Thus, it cannot be recommended to be performed when evaluating and monitoring age-related macular degeneration patients in the daily clinic.

journal_name

Eur J Ophthalmol

authors

Coco-Martín RM,Pichel-Mouzo M,Fernández I,Plata-Cordero M,Lopez-Miguel A

doi

10.1177/1120672119870362

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

1480-1486

issue

6

eissn

1120-6721

issn

1724-6016

journal_volume

30

pub_type

杂志文章
  • Intraocular pressure measurements in diabetes mellitus.

    abstract:PURPOSE:To investigate the impact of diabetes mellitus-induced changes on intraocular pressure measurements using Goldmann applanation tonometry, Ocular Response Analyzer, and Corvis ST. METHODS:Measurements were done using Goldmann applanation tonometry, Ocular Response Analyzer, and Corvis ST in 69 diabetic patients...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119890517

    authors: Ramm L,Herber R,Spoerl E,Pillunat LE,Terai N

    更新日期:2020-11-01 00:00:00

  • Recurrent corneal erosion following uneventful IntraLASIK treated by phototherapeutic keratectomy.

    abstract:PURPOSE:To report on phototherapeutic keratectomy (PTK) in myopic patients who developed spontaneous recurrent corneal erosions (RCE) following IntraLASIK. METHODS:Recurrent corneal erosions developed spontaneously 3-6 months following IntraLASIK in 4 eyes of 4 myopic patients. Diffuse lamellar keratitis (DLK) subsequ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000097

    authors: Kremer I

    更新日期:2012-01-01 00:00:00

  • The effect of levodopa and dopamine agonists on optic nerve head in Parkinson disease.

    abstract:PURPOSE:To evaluate the effects of levodopa and dopamine agonists on retinal nerve fiber layer using scanning laser ophthalmoscope. METHODS:Forty-four patients with the diagnosis of Parkinson disease and receiving levodopa or dopamine agonist monotherapy were included in this prospective study. The control group consi...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210701700520

    authors: Yavas GF,Yilmaz O,Küsbeci T,Oztürk F

    更新日期:2007-09-01 00:00:00

  • Surgical removal of subfoveal choroidal neovascularization: visual outcome and prognostic value of fluorescein angiography and optical coherence tomography.

    abstract:PURPOSE:To study the functional results of macular surgery and determine pre-operative features associated with better final visual outcome. METHODS:Forty-two consecutive patients underwent surgical removal of subfoveal choroidal neovascularization (CNV), related to age-related macular degeneration (AMD) in 8 eyes, de...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210101100313

    authors: Brindeau C,Glacet-Bernard A,Coscas F,Mimoun G,Boukhli L,Coscas G,Soubrane G

    更新日期:2001-07-01 00:00:00

  • Induction of controlled wound healing with PMMA segments in the deep stroma in corneas of hens.

    abstract:PURPOSE:Polymethylmethacrylate (PMMA) segments are normally used in additive surgery to treat both corneal ectasia post laser-assisted in situ keratomileusis and keratoconus. The aim of this work was to develop an experimental animal model to induce wound healing in the deep stroma in corneas of hens. METHODS:PMMA seg...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067211002000108

    authors: Merayo-Lloves J,Blanco-Mezquita T,Ibares-Frias L,Fabiani L,Alvarez-Barcia A,Martinez-Garcia C

    更新日期:2010-01-01 00:00:00

  • Timogel® vs timolol 0.5% ophthalmic solution: efficacy, safety, and acceptance.

    abstract:PURPOSE:To evaluate the efficacy, safety, and tolerability of Timogel® preservative-free once daily compared to timolol 0.5% ophthalmic solution bid in patients with ocular hypertension (OHT) and patients with primary open-angle glaucoma (POAG). METHODS:A total of 75 patients with OHT and patients with POAG treated wi...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000006

    authors: Rolle T,Curto D,Alovisi C,Franzone M,Brogliatti B,Grignolo FM

    更新日期:2012-01-01 00:00:00

  • Complications of cataract surgery in eyes filled with silicone oil.

    abstract:INTRODUCTION:The aim of the study was to evaluate complications of cataract surgery in eyes filled with silicone oil. METHODS:This retrospective, noncomparative, consecutive case series analyzed medical files of patients with eyes filled with silicone oil undergoing cataract surgery. Phacoemulsification with posterior...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672117753700

    authors: Kanclerz P,Grzybowski A,Schwartz SG,Lipowski P

    更新日期:2018-07-01 00:00:00

  • Technique for autologous nasal mucosa transplantation in severe ocular surface disease.

    abstract:PURPOSE:To describe the detailed surgical technique used for harvesting and transplantation of autologous nasal mucosa grafts for ocular surface reconstruction, to evaluate the clinical results and utility of autologous nasal mucosa grafts in ocular surface diseases. METHODS:Autologous nasal mucosa was harvested from ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/EJO.2011.6336

    authors: Chun YS,Park IK,Kim JC

    更新日期:2011-09-01 00:00:00

  • Large choroidal excavation in a patient with rubella retinopathy.

    abstract:PURPOSE:To describe a case of rubella retinopathy complicated by bilateral choroidal neovascularization (CNV) and late development of large choroidal excavation (LCE). METHODS:A 19-year-old woman with a diagnosis of rubella retinopathy underwent her annual ophthalmologic examination, including visual acuity testing an...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5001056

    authors: Parodi MB,Romano F,Montagna M,Bandello F

    更新日期:2018-03-01 00:00:00

  • Can intravitreal tissue plasminogen activator and SF6 gas facilitate management of macular degeneration with photodynamic therapy?

    abstract:PURPOSE:To describe the safety and efficacy of intravitreal tissue plasminogen activator (tPA) and sulfur hexafluoride (SF6) gas with sequential photodynamic therapy (PDT) in the management of submacular hemorrhage (SMH) associated with macular degeneration (MD). METHODS:Consecutive case series of five patients presen...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210801800415

    authors: Muqit MM,Ghanchi FD

    更新日期:2008-07-01 00:00:00

  • Silicone oil-induced displacement of subretinal hemorrhage in age-related macular degeneration.

    abstract:PURPOSE:To describe the use of silicone oil (SO) in combination with subretinal recombinant tissue plasminogen activator (rtPA) to achieve dislocation of large subretinal hemorrhage secondary to exudative age-related macular degeneration (AMD). METHODS:A single-eye 81-year-old woman, known for exudative AMD, presented...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120952349

    authors: Corbelli E,Iuliano L,Fogliato G,Bandello F,Codenotti M

    更新日期:2020-08-18 00:00:00

  • Idiopathic sclerosing inflammation of the orbit: a case of steroid-responsive disease in a patient with auto-immune hemolytic anemia.

    abstract:PURPOSE:Idiopathic sclerosing orbital inflammation (ISOI) has been categorized by some authors as a unique clinicopathologic entity, separate from the heterogeneous group of disorders known collectively as nonspecific orbital inflammation. Histologic similarity and clinical association with other fibrosclerosing condit...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210501500214

    authors: Billing KJ,Hsuan J,Selva D

    更新日期:2005-03-01 00:00:00

  • Diurnal variation of corneal biomechanics and intraocular pressure in normal subjects.

    abstract:PURPOSE:To assess and investigate the relationship between diurnal variations in intraocular pressure (IOP) and biomechanical properties of cornea. METHODS:Sixty-two healthy volunteers were recruited. Corneal compensated IOP (IOPcc), Goldmann-correlated IOP (IOPg), corneal resistance factor (CRF), and corneal hysteres...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210901900518

    authors: Oncel B,Dinc UA,Gorgun E,Yalvaç BI

    更新日期:2009-09-01 00:00:00

  • Electrophysiological approaches for early detection of glaucoma.

    abstract:PURPOSE:While elevated intraocular pressure (IOP) is a major risk factor for glaucoma, only about 1% of patients with 25 mmHg develop the condition each year. Since a sizeable proportion of the ganglion cells are already lost when the visual field losses are apparent, the aim is to identify patients with elevated IOP i...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1177/112067210101102s05

    authors: Bach M

    更新日期:2001-07-01 00:00:00

  • Information used to decide on retreatment of exudative age-related macular degeneration with 
anti-VEGF in clinical practice.

    abstract::Purpose. To record the information used in order to make a retreatment decision in patients with exudative age-related macular degeneration (AMD) and to assess if an optical coherence tomography (OCT)-only follow-up clinic would suffice.
Methods. Two hundred patients under treatment with intravitreal anti-vascular end...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000190

    authors: Manousaridis K,Manjunath V,Talks J

    更新日期:2012-08-06 00:00:00

  • Myogenic response reduction by high blood glucose levels in human retinal arterioles.

    abstract:PURPOSE:The effect of elevated blood glucose level on the myogenic response of human retinal arterioles to acute increases in blood pressure is investigated. METHODS:The vascular response to raised blood pressure (Bayliss effect) was measured in 12 healthy volunteers by use of the retinal vessel analyzer (RVA). For a ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210501500109

    authors: Blum M,Brändel C,Müller UA

    更新日期:2005-01-01 00:00:00

  • Two nonsense mutations of PAX6 in two Japanese aniridia families: case report and review of the literature.

    abstract:PURPOSE:To identify PAX6 mutations in patients from four Japanese families with aniridia. METHODS:Polymerase chain reaction (PCR)-single stand conformational polymorphism (SSCP) analysis (SSCA) was performed in probands of the families, and restriction analysis using MaeIII or AvaI was carried out in other affected fa...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1177/112067210001000213

    authors: Kondo-Saitoh A,Matsumoto N,Sasaki T,Egashira M,Saitoh A,Yamada K,Niikawa N,Amemiya T

    更新日期:2000-04-01 00:00:00

  • Unmet visual needs of children with Down syndrome in an African population: implications for visual and cognitive development.

    abstract:PURPOSE:To determine the magnitude and types of ocular disorders in children with Down syndrome in an African population and to assess to what extent these visual needs have been met.
 METHODS:This is a cross-sectional study of children with Down syndrome attending a school for the mentally challenged in Southeastern ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000222

    authors: Aghaji AE,Lawrence L,Ezegwui I,Onwasigwe E,Okoye O,Ebigbo P

    更新日期:2013-05-01 00:00:00

  • Visual acuity, contrast sensitivity, subjective quality of vision, and quality of life with 4 different multifocal IOLs.

    abstract:PURPOSE:This prospective, randomized, double-masked, clinical trial was designed to evaluate visual acuity, contrast sensitivity, subjective quality of vision, and quality of life in 47 patients symmetrically, and randomly, implanted with 4 different IOL designs (SN6AD1, SN60D3, ReZoom NXG1, and Tecnis ZMA00), 3 months...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.5301/EJO.2011.8371

    authors: Gil MA,Varon C,Rosello N,Cardona G,Buil JA

    更新日期:2012-03-01 00:00:00

  • Comparison of 4 techniques for limbal-conjunctival autograft fixation in primary pterygium surgery.

    abstract:PURPOSE:To compare 4 limbal-conjunctival autograft fixation techniques-conventional suture, commercial fibrin glue, autologous fibrin glue, and cautery-in primary nasal pterygium surgery. METHODS:This is a retrospective and descriptive study. The postoperative patient discomfort, graft edema, ocular inflammation, and ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000924

    authors: Mejía LF,Santamaría JP,Cuevas M,Córdoba A,Carvajal SA

    更新日期:2017-06-26 00:00:00

  • Simultaneous bilateral retinal detachment following coronary artery bypass graft: case report.

    abstract:PURPOSE:To present an unusual case of simultaneous bilateral retinal detachment (RD) following a coronary artery bypass graft in a patient with acute myocardial infarction (AMI). METHODS:A 78-year-old man was first seen for bilateral sudden visual loss after surgical treatment of AMI. The patient underwent ultrasound ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210701700530

    authors: Ceruti P,Tosi R,Marchini G

    更新日期:2007-09-01 00:00:00

  • Ocular and orbital complications following the treatment of retinoblastoma.

    abstract:PURPOSE:To investigate the ocular and orbital complications observed in children treated for retinoblastoma. SUBJECTS AND METHODS:We retrospectively studied 73 children (39 boys, 34 girls) suffering from retinoblastoma. Thirty-six had bilateral tumor and 37 unilateral disease for a total of 109 eyes affected. The foll...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Anteby I,Ramu N,Gradstein L,Miskin H,Pe'er J,Benezra D

    更新日期:1998-04-01 00:00:00

  • Ultrasound biomicroscopy findings in peripheral vitreoretinal toxocariasis.

    abstract:PURPOSE:To describe the morphologic alterations in ultrasound biomicroscopy (UBM) present in peripheral vitreoretinal toxocariasis. METHODS:An observational prospective study of case series. Fifteen eyes of 15 patients with clinical and laboratory diagnosis of peripheral vitreoretinal toxocariasis were enrolled. The p...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210401400208

    authors: Cella W,Ferreira E,Torigoe AM,Macchiaverni-Filho N,Balarin V

    更新日期:2004-03-01 00:00:00

  • Retinal and choroidal thicknesses measured with swept-source optical coherence tomography after surgery for idiopathic macular hole.

    abstract:PURPOSE:To evaluate the changes in retinal nerve fiber layer thickness (RNFLT), ganglion cell layer thickness (GCLT), retinal thickness (RT), and subfoveal choroidal thickness (SFCT) in eyes that received pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling for idiopathic macular hole (IMH) and to ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000851

    authors: Bardak H,Gunay M,Bardak Y,Ercalik Y

    更新日期:2017-05-11 00:00:00

  • Endophthalmitis associated with fungal keratitis and penetrating injuries in North China.

    abstract:PURPOSE:To report the laboratory findings, management strategies, and visual outcomes of culture-proven exogenous fungal endophthalmitis in North China. METHODS:The microbiological and treatment records of patients with culture-positive exogenous fungal endophthalmitis who visited the Affiliated Hospital of Qingdao Un...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119833896

    authors: Liu MY,Zhang L,Yin XL,Sun SY

    更新日期:2020-05-01 00:00:00

  • Rituximab in the treatment of Susac's syndrome: Report of a case.

    abstract:SIGNIFICANCE:Susac's syndrome is a rare retinocochleocerebral immune-mediated endotheliopathy and clinically manifests as a pathognomonic triad of encephalopathy, hearing loss, and branch retinal artery occlusion. This triad is rarely present at symptom onset, thus, it is often initially misdiagnosed. To date, Susac's ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120924545

    authors: Monferrer-Adsuara C,Remolí-Sargues L,Hernández-Bel L,Gracia-García A,Hernández-Garfella ML,Cervera-Taulet E

    更新日期:2020-05-07 00:00:00

  • Laser-assisted subepithelial keratectomy (LASEK) without alcohol versus photorefractive keratectomy (PRK).

    abstract:PURPOSE:To evaluate epithelial healing and visual outcome after laser-assisted subepithelial keratectomy (LASEK) without alcohol de-epithelialization and to compare this technique to photorefractive keratectomy (PRK) in myopia. METHODS:In a series of 1953 patients undergoing bilateral myopic PRK, an epithelial flap co...

    journal_title:European journal of ophthalmology

    pub_type: 临床试验,杂志文章

    doi:10.1177/112067210301300802

    authors: Leccisotti A

    更新日期:2003-10-01 00:00:00

  • Spontaneous extrusion of a stainless steel glaucoma drainage implant (Ex-PRESS).

    abstract:PURPOSE:To report a case of spontaneous extrusion of a stainless steel glaucoma drainage implant (Ex-PRESS). METHODS:An Ex-PRESS was implanted under the conjunctiva in a 76-year-old man with primary open-angle glaucoma. RESULTS:Two years after implantation, the Ex-Press extruded spontaneously. Despite this adverse ev...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Tavolato M,Babighian S,Galan A

    更新日期:2006-09-01 00:00:00

  • Single night postoperative prone posturing in idiopathic macular hole surgery.

    abstract:PURPOSE:To evaluate the role of postoperative prone posturing for a single night in the outcome of trans pars plana vitrectomy (TPPV) with internal limiting membrane (ILM) peel and 20% perfluoroethane (C2F6) internal tamponade for idiopathic macular hole. METHODS:This prospective trial enrolled 14 eyes in 14 consecuti...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000039

    authors: Malik A,Dooley I,Mahmood U

    更新日期:2012-05-01 00:00:00

  • Deep sclerectomy in primary open-angle glaucoma and exfoliative glaucoma.

    abstract:PURPOSE:To study the effect of deep sclerectomy (DS) in primary open-angle glaucoma (POAG) and exfoliative glaucoma (EXG). METHODS:We retrospectively analyzed the intraocular pressure (IOP)-lowering effect of DS in 235 consecutive eyes. Eyes were divided into 2 groups according to glaucoma subtype: POAG (127 eyes) and...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000762

    authors: Suominen SM,Harju MP,Vesti ET

    更新日期:2016-11-04 00:00:00