Branch occlusive disease: clinical and magnetic resonance angiography findings.

abstract：OBJECTIVE:We aimed to create an index to stratify cryptogenic stroke (CS) patients with patent foramen ovale (PFO) by their likelihood that the stroke was related to their PFO. METHODS:Using data from 12 component studies, we used generalized linear mixed models to predict the presence of PFO among patients with CS, a...

journal_title：Neurology

authors： Kent DM,Ruthazer R,Weimar C,Mas JL,Serena J,Homma S,Di Angelantonio E,Di Tullio MR,Lutz JS,Elkind MS,Griffith J,Jaigobin C,Mattle HP,Michel P,Mono ML,Nedeltchev K,Papetti F,Thaler DE

更新日期：2013-08-13 00:00:00

abstract：BACKGROUND:Previous studies have examined the role of APOE variation in multiple sclerosis (MS), but have lacked the statistical power to detect modest genetic influences on risk and disease severity. The meta- and pooled analyses presented here utilize the largest collection, to date, of MS cases, controls, and famili...

journal_title：Neurology

authors： Burwick RM,Ramsay PP,Haines JL,Hauser SL,Oksenberg JR,Pericak-Vance MA,Schmidt S,Compston A,Sawcer S,Cittadella R,Savettieri G,Quattrone A,Polman CH,Uitdehaag BM,Zwemmer JN,Hawkins CP,Ollier WE,Weatherby S,Enzinger C

更新日期：2006-05-09 00:00:00

abstract：OBJECTIVE:To determine the relationship between hippocampal, amygdalar, and entorhinal cortex atrophy and duration of epilepsy, presence of secondary generalized seizures, and prolonged childhood febrile convulsions in patients with pharmacologically intractable temporal lobe epilepsy (TLE). METHODS:Volumetric MRI of ...

journal_title：Neurology

authors： Bernasconi N,Natsume J,Bernasconi A

更新日期：2005-07-26 00:00:00

abstract：OBJECTIVE:To examine the relationship of migraine and other severe headaches with panic disorder. METHODS:Representative samples of persons with migraine, non-migrainous severe headaches, and controls with no history of severe headaches, identified by a telephone survey, were interviewed in person, using a standardize...

journal_title：Neurology

authors： Breslau N,Schultz LR,Stewart WF,Lipton R,Welch KM

更新日期：2001-02-13 00:00:00

abstract：OBJECTIVE:The assessment of behavioral disturbances in amyotrophic lateral sclerosis (ALS) is important because of the overlap with the behavioral variant of frontotemporal dementia (ALS-bvFTD). Motor symptoms and dysarthria are not taken into account in currently used behavioral questionnaires. We examined the clinime...

journal_title：Neurology

authors： Raaphorst J,Beeldman E,Schmand B,Berkhout J,Linssen WH,van den Berg LH,Pijnenburg YA,Grupstra HF,Weikamp JG,Schelhaas HJ,Papma JM,van Swieten JC,de Visser M,de Haan RJ

更新日期：2012-09-25 00:00:00

abstract：:To evaluate when it is possible to discontinue anticonvulsant treatment in children with cryptogenic partial epilepsy, the authors studied 89 epileptic children divided into two groups: Group A, 45 children whose therapy was discontinued after 1 year from the last seizure; and Group B, 44 children whose therapy was st...

journal_title：Neurology

authors： Verrotti A,Morresi S,Basciani F,Cutarella R,Morgese G,Chiarelli F

更新日期：2000-11-14 00:00:00

abstract：OBJECTIVE:To determine the incidence and clinical effects of antibodies that develop during treatment with natalizumab. METHODS:In two randomized, double-blind, placebo-controlled studies (natalizumab safety and efficacy in relapsing remitting multiple sclerosis [MS, AFFIRM] and safety and efficacy of natalizumab in c...

journal_title：Neurology

authors： Calabresi PA,Giovannoni G,Confavreux C,Galetta SL,Havrdova E,Hutchinson M,Kappos L,Miller DH,O'Connor PW,Phillips JT,Polman CH,Radue EW,Rudick RA,Stuart WH,Lublin FD,Wajgt A,Weinstock-Guttman B,Wynn DR,Lynn F,Panzar

更新日期：2007-10-02 00:00:00

abstract：OBJECTIVE:To determine the risk, predictors, and prognosis of independence loss and institutionalization in patients with early Parkinson disease (PD). METHODS:We conducted a prospective population-based 5-year longitudinal study following 189 patients with incident PD and 174 controls matched for age, sex, and comorb...

journal_title：Neurology

authors： Bjornestad A,Tysnes OB,Larsen JP,Alves G

更新日期：2016-10-11 00:00:00

abstract：BACKGROUND:Recent studies demonstrated an excess of winter births in children with brain tumors and in adults with various neurologic or psychiatric diseases relative to the general population. OBJECTIVE:To investigate a possible association between month of birth and risk of brain tumors in adults using data from a l...

journal_title：Neurology

authors： Brenner AV,Linet MS,Shapiro WR,Selker RG,Fine HA,Black PM,Inskip PD

更新日期：2004-07-27 00:00:00

abstract：BACKGROUND:In the late 19th century, a man with a psychogenic movement disorder was evaluated by many of the Philadelphia neurologists associated with Silas Weir Mitchell. In 1885, prior to the development of movie cameras or projectors, the patient was photographed by pioneering photographer Eadweard Muybridge, in col...

journal_title：Neurology

authors： Lanska DJ

更新日期：2015-01-27 00:00:00

abstract：:In a prospective cohort of 124 encephalopathic term infants, six infants had an acute focal stroke. All six encephalopathic patients with strokes presented with seizures. Neurodevelopmental outcome at 30 months was abnormal in all six patients and significantly worse when compared with the entire cohort overall. These...

journal_title：Neurology

authors： Ramaswamy V,Miller SP,Barkovich AJ,Partridge JC,Ferriero DM

更新日期：2004-06-08 00:00:00

abstract：:Endovascular therapy for acute ischemic stroke continues to evolve to improve both efficacy and safety. In the late 1990 s, intra-arterial chemical thrombolysis with prourokinase was shown to be effective in achieving partial recanalization and improving clinical outcome, in comparison with intra-arterial heparin admi...

journal_title：Neurology

authors： Novakovic RL,Toth G,Narayanan S,Zaidat OO

更新日期：2012-09-25 00:00:00

abstract：OBJECTIVE:To compare in the Vertebral Artery Ischaemia Stenting Trial (VIST) the risks and benefits of vertebral angioplasty and stenting with best medical treatment (BMT) alone for symptomatic vertebral artery stenosis. METHODS:VIST was a prospective, randomized, open-blinded endpoint clinical trial performed in 14 h...

journal_title：Neurology

authors： Markus HS,Larsson SC,Kuker W,Schulz UG,Ford I,Rothwell PM,Clifton A,VIST Investigators.

更新日期：2017-09-19 00:00:00

abstract：OBJECTIVE:To evaluate topiramate as monotherapy in adults and children with recently diagnosed, localization-related epilepsy, comparing two dosages of topiramate in a multicenter, randomized, double-blind study. METHODS:Adults and children (>/=3 years of age) were eligible if the maximum interval since epilepsy diagn...

journal_title：Neurology

authors： Gilliam FG,Veloso F,Bomhof MA,Gazda SK,Biton V,Ter Bruggen JP,Neto W,Bailey C,Pledger G,Wu SC

更新日期：2003-01-28 00:00:00

abstract：OBJECTIVES:To evaluate the frequency, clinical and etiologic features, and short- and long-term outcomes of early recurrent TIA. METHODS:This prospective observational cohort study enrolled all consecutive patients with TIA referred to our emergency department and diagnosed by a vascular neurologist. Expedited assessm...

journal_title：Neurology

authors： Foschi M,Pavolucci L,Rondelli F,Spinardi L,Favaretto E,Filippini M,Degli Esposti D,Strocchi E,Faggioli G,Cortelli P,Guarino M,Bologna TIA Study-Group.

更新日期：2020-09-22 00:00:00

abstract：OBJECTIVES:To examine associations between 1H magnetic resonance spectroscopic imaging (1H MRSI)-detected hippocampal creatine to N-acetylaspartate (Cr/NAA) ratios and neuropsychological measures sensitive to mesial temporal lobe function. BACKGROUND:The measurement of 1H MRSI-detected hippocampal metabolites has prov...

journal_title：Neurology

authors： Martin RC,Sawrie S,Hugg J,Gilliam F,Faught E,Kuzniecky R

更新日期：1999-12-10 00:00:00

abstract：:We evaluated the relationship between mesial temporal seizure focus and serum prolactin (PRL) in patients before and after they underwent anterior temporal lobectomy (ATL) for medically intractable temporal lobe epilepsy (TLE). These patients had a confirmed unilateral epileptogenic focus in mesial temporal structures...

journal_title：Neurology

authors： Lin YY,Su MS,Yiu CH,Shih YH,Yen DJ,Kwan SY,Wu ZA,Chan SH

更新日期：1997-08-01 00:00:00

abstract：:The incidence of MS was assessed in a nationwide cohort study of 31,990 employees of Danish utility companies between 1900 and 1993. Overall, 32 cases of MS were diagnosed, as compared with 23.7 expected from national incidence rates, to yield a standardized incidence ratio of 1.35 (95% confidence interval, 0.92 to 1....

journal_title：Neurology

authors： Johansen C,Koch-Henriksen N,Rasmussen S,Olsen JH

更新日期：1999-04-12 00:00:00

abstract：:HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is endemic in the Caribbean basin and Japan. Because of the close proximity of the United States to the Caribbean and the presence of HTLV-I-seropositive persons in the United States, we sought reports of patients who were HTLV-I seropositive and had ...

journal_title：Neurology

authors： Janssen RS,Kaplan JE,Khabbaz RF,Hammond R,Lechtenberg R,Lairmore M,Chiasson MA,Punsalang A,Roberts B,McKendall RR

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVE:To determine whether brain function is altered in cognitively normal individuals at high risk for AD several years before the typical age at onset for this illness. BACKGROUND:Neuropathologic alterations in AD precede cognitive impairment by several years. It is unknown whether functional alterations in neur...

journal_title：Neurology

authors： Smith CD,Andersen AH,Kryscio RJ,Schmitt FA,Kindy MS,Blonder LX,Avison MJ

更新日期：1999-10-22 00:00:00

abstract：OBJECTIVE:Compare the cost and effectiveness of nonbenzodiazepine antiepileptic drugs (non-BZD AEDs) for treatment of BZD-resistant convulsive status epilepticus (SE). METHODS:Decision analysis model populated with effectiveness data from a systematic review and meta-analysis of the literature, and cost data from publ...

journal_title：Neurology

authors： Sánchez Fernández I,Gaínza-Lein M,Lamb N,Loddenkemper T

更新日期：2019-05-14 00:00:00

abstract：:We compared the number of new gadolinium-enhancing and T2-weighted lesions on six monthly MRI scans in eight patients with relapsing multiple sclerosis before and during treatment with weekly intramuscular interferon beta-1a (Avonex; 30 microg). MRI activity was modestly reduced during treatment (p = 0.016). The treat...

journal_title：Neurology

authors： Waubant E,Goodkin DE,Sloan R,Andersson PB

更新日期：1999-09-11 00:00:00

abstract：:The forearm segment of the ulnar nerve is difficult to assess if the nerve has been injured severely at the wrist. A new, simple nerve conduction technique of recording from the sensory dorsal branch of the nerve localizes the lesion and enables easier evaluation of that segment than do other techniques. ...

journal_title：Neurology

authors： Jabre JF

更新日期：1980-08-01 00:00:00

abstract：OBJECTIVE:To describe the clinical features, neuropathology, and genetic studies in a family with autosomal dominant frontotemporal dementia (FTD). BACKGROUND:Clinical Pick's disease, or FTD with parkinsonism, has been described in several families linked to chromosome 17 (FTDP-17). Most of these have shown tau protei...

journal_title：Neurology

authors： Kertesz A,Kawarai T,Rogaeva E,St George-Hyslop P,Poorkaj P,Bird TD,Munoz DG

更新日期：2000-02-22 00:00:00

abstract：:Plasma levels of six short-chain fatty acids (SCFA) were measured in 23 Reye's syndrome patients. In sequential measurements, only propionic acid correlated closely with neurologic severity. Although admission SCFA levels were slightly elevated, there were no significant differences between patients grouped by severit...

journal_title：Neurology

authors： McArthur B,Sarnaik AP,Mitchell RA

更新日期：1984-06-01 00:00:00

abstract：:Eighty-eight multiple sclerosis case-friend pairs were interviewed by telephone to elicit information about early-life exposures. Available mothers were also interviewed. Risk factors included childhood diseases, exposures to animals, and residence. We found a positive association between MS and having measles at a la...

journal_title：Neurology

authors： Sullivan CB,Visscher BR,Detels R

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:Neutralizing antibodies (NAB) to interferon beta (IFNbeta) occur in about one-third of MS patients treated with IFNbeta-1b and there is an association with a loss of clinical and MRI efficacy. However, there are no data regarding the bioavailability of IFNbeta-1b in patients with and without NAB. METHODS:Th...

journal_title：Neurology

authors： Deisenhammer F,Reindl M,Harvey J,Gasse T,Dilitz E,Berger T

更新日期：1999-04-12 00:00:00

abstract：BACKGROUND:The paradoxical phenomenon of relative longevity among obese patients with established diseases has been reported for various disease conditions. The authors sought to investigate whether the obesity paradox also applies to intracerebral hemorrhage (ICH) survivors. METHODS:A total of 1,604 patients with ICH...

journal_title：Neurology

authors： Kim BJ,Lee SH,Ryu WS,Kim CK,Lee J,Yoon BW

更新日期：2011-02-08 00:00:00

abstract：:The syndrome of increased intracranial pressure without hydrocephalus or mass lesion and with normal CSF composition, previously referred to as pseudotumor cerebri, is a diagnosis of exclusion now termed idiopathic intracranial hypertension (IIH). Diagnostic criteria of this disorder have not been updated since the Mo...

journal_title：Neurology

authors： Friedman DI,Jacobson DM

更新日期：2002-11-26 00:00:00

abstract：:Since cytomegalovirus (CMV) has been implicated in the pathogenesis of Rasmussen's syndrome, we treated four patients with ganciclovir, a potent anti-CMV drug. A 7-year-old girl with seizures escalating to 60/day over 3 months despite triple antiepileptic drug therapy became seizure-free 5 days after initiation of tre...

journal_title：Neurology

authors： McLachlan RS,Levin S,Blume WT

更新日期：1996-10-01 00:00:00