An automatic wash method for dimethyl sulfoxide removal in autologous hematopoietic stem cell transplantation decreases the adverse effects related to infusion.

abstract：:The development of flexible plastic blood bags has permitted effective blood component production and therapy. However, the plasticizer di(2-ethylhexyl)phthalate (DEHP), whose toxicity in humans is still undefined, is known to leach from the plastic into stored blood. Despite the availability of bags made of plastics ...

journal_title：Transfusion

authors： Rock G,Tocchi M,Ganz PR,Tackaberry ES

更新日期：1984-11-01 00:00:00

abstract：:Transfusion-transmitted cytomegalovirus (TT-CMV) is often asymptomatic, but certain patient populations, such as very low birth weight neonates, fetuses requiring intrauterine transfusion, pregnant women, patients with primary immunodeficiencies, transplant recipients, and patients receiving chemotherapy or transplant...

journal_title：Transfusion

authors： AABB, Clinical Transfusion Medicine Committee.,Heddle NM,Boeckh M,Grossman B,Jacobson J,Kleinman S,Tobian AA,Webert K,Wong EC,Roback JD

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The overall risk of hemolytic transfusion reactions (HTRs) from plasma (minor)-incompatible platelet (PLT) transfusions and the role of a critical anti-A or anti-B titer in predicting and preventing these reactions has not been clearly established. STUDY DESIGN AND METHODS:We evaluated all apheresis PLT (AP...

journal_title：Transfusion

authors： Karafin MS,Blagg L,Tobian AA,King KE,Ness PM,Savage WJ

更新日期：2012-10-01 00:00:00

abstract：:After 30 years of hematopoietic stem cell use for various indications, umbilical cord blood is considered as an established source of cells with marrow and postmobilization peripheral blood. The limited number of cells still remains a problematic element restricting their use, especially in adults who require to be gr...

journal_title：Transfusion

authors： Faivre L,Couzin C,Boucher H,Domet T,Desproges A,Sibony O,Bechard M,Vanneaux V,Larghero J,Cras A

更新日期：2018-02-01 00:00:00

abstract：:Data collected from 50 saline washed units of red blood cells shows that units washed with one liter of 0.9 per cent NaCl on an IBM cell processor have an average hematocrit of 72.2 per cent, with 84.7 per cent of the white blood cells removed, and only 0.6 per cent of the original total protein remaining. The red blo...

journal_title：Transfusion

authors： Wooten MJ

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:A single injection of pegfilgrastim has been shown to be equivalent to daily filgrastim in enhancing neutrophil recovery after chemotherapy, whereas the experiences with pegfilgrastim in mobilization of peripheral blood progenitor cells (PBPCs) are limited. STUDY DESIGN AND METHODS:Forty unselected patients...

journal_title：Transfusion

authors： Kroschinsky F,Hölig K,Platzbecker U,Poppe-Thiede K,Ordemann R,Blechschmidt M,Oelschlaegel U,Schaich M,Hänel M,Bornhäuser M,Ehninger G

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:We evaluate the current prevalence of serologic markers for hepatitis B virus (HBV) and hepatitis C virus (HCV) in blood donors and estimated HCV incidence and residual transfusion-transmitted risk at three large Brazilian blood centers. STUDY DESIGN AND METHODS:Data on whole blood and platelet donations we...

journal_title：Transfusion

authors： de Almeida-Neto C,Sabino EC,Liu J,Blatyta PF,Mendrone-Junior A,Salles NA,Leão SC,Wright DJ,Basques FV,Ferreira JE,Busch MP,Murphy EL,NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component.

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:This study evaluated the effect of routine, uncontrolled, Israeli field storage conditions on the stability and efficacy of Lyo-Plas N freeze-dried plasma (FDP). We evaluated clotting factors V, VIII, and XI; proteins S and C; fibrinogen; partial thromboplastin time (PTT); antithrombin III (ATIII); von Wille...

journal_title：Transfusion

authors： Zur M,Glassberg E,Gorenbein P,Epstein E,Eisenkraft A,Misgav M,Avramovich E

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Hemoglobin (Hb)-based oxygen (O2 ) carriers (HBOCs) are being developed as alternatives to red blood cells and blood when these products are unavailable. Clinical trials of previous HBOC generations revealed side effects, including hypertension and vasoconstriction, that were not observed in preclinical stud...

journal_title：Transfusion

authors： Muller CR,Williams AT,Munoz CJ,Eaker AM,Breton AN,Palmer AF,Cabrales P

更新日期：2020-10-26 00:00:00

abstract：BACKGROUND:Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related mortality. In the past decade blood banks have implemented low-risk TRALI donor strategies, including a male-only donor policy for plasma-containing blood products to prevent onset of TRALI. We performed a meta-analysis...

journal_title：Transfusion

authors： Müller MC,van Stein D,Binnekade JM,van Rhenen DJ,Vlaar AP

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Human platelet antigens (HPAs) are polymorphisms in platelet membrane glycoproteins (GPs) that can stimulate production of alloantibodies once exposed to foreign platelets (PLTs) with different HPAs. These antibodies can cause neonatal alloimmune thrombocytopenia, posttransfusion purpura, and PLT transfusion...

journal_title：Transfusion

authors： Landau M,Rosenberg N

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:To fully evaluate the safety and efficacy of umbilical cord blood (UCB) as a source of hematopoietic progenitor cells, UCB banks are being established worldwide to provide a readily accessible resource of stem and progenitor cells for allogeneic transplantation. Guidelines for UCB donor criteria have been pr...

journal_title：Transfusion

authors： Jefferies LC,Albertus M,Morgan MA,Moolten D

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Iron deficiency leading to low hemoglobin concentration (cHb) is a common problem for blood donors as well as for blood banks. A standardized protocol offering iron supplementation based on P-ferritin determination may help to reduce the problem and retain donors. STUDY DESIGN AND METHODS:This was a prospec...

journal_title：Transfusion

authors： Magnussen K,Bork N,Asmussen L

更新日期：2008-04-01 00:00:00

abstract：:Three examples of an antibody defining a 'new' high frequency red blood cell antigen, Era, are described. Family studies show Era to be inherited, but the mode of inheritance may not be straightforward. ...

journal_title：Transfusion

authors： Daniels GL,Judd WJ,Moore BP,Neitzer G,Ouellet P,Plantos M,Verrette S

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:A reliable, validated method for rapidly determining HPC viability is essential for clinical cell engineering. STUDY DESIGN AND METHODS:A fluorometric cell viability assay using acridine orange and propidium iodide (AO/PI) was compared to the current standard, trypan blue (TB) exclusion. Viable cells staine...

journal_title：Transfusion

authors： Mascotti K,McCullough J,Burger SR

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:QWALYS 2 is a fully automated system for ABO/D grouping, Rh phenotyping, K typing, and antibody screening (ABS). Its new erythrocyte-magnetized technology (EMT) is based on the use of magnetic nanoparticles and avoids centrifugation and washing steps. STUDY DESIGN AND METHODS:Overall 499 blood samples were ...

journal_title：Transfusion

authors： Schoenfeld H,Bulling K,von Heymann C,Neuner B,Kalus U,Kiesewetter H,Pruss A

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Recombinant activated factor VII (rFVIIa) is being tested to improve hemostasis in a variety of bleeding disorders. Clinical indications and efficacy are still being evaluated for this product. CASE REPORT:Over a 17-month period, rFVIIa was used to treat central nervous system hemorrhage in three patients w...

journal_title：Transfusion

authors： Huang WY,Kruskall MS,Bauer KA,Uhl L,Shaz BH

更新日期：2004-11-01 00:00:00

abstract：:This article introduces a new method of component preparation that is capable of producing white cell (WBC)-reduced platelet concentrates (PCs) from whole blood. Whole blood is separated into packed red cells (RBCs) and platelet-rich plasma (PRP) by centrifugation, and the PRP is expressed through a newly designed WBC...

journal_title：Transfusion

authors： Dzik WH,Cusack WF,Gacek MJ

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Studies have demonstrated that immunity against platelet (PLT) transfusions is dependent on recipient antigen-presenting cells (APCs) and their ability to produce nitric oxide (NO). To further analyze this, we focused on NO's major metabolite peroxynitrite (ONOO(-)) and its ability to affect PLT immunity. S...

journal_title：Transfusion

authors： Semple JW,Speck ER,Fabron A Jr,Kim RA,Freedman J

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Transfusion of platelet concentrates (PCs) is the basic treatment for severe platelet disorders. PCs carry the risk of pathogen transmission, especially bacteria. Pathogen reduction (PR) by addition of photochemical reagents and irradiation with visible or ultraviolet (UV) light can significantly reduce this...

journal_title：Transfusion

authors： Mohr H,Steil L,Gravemann U,Thiele T,Hammer E,Greinacher A,Müller TH,Völker U

更新日期：2009-12-01 00:00:00

abstract：:A modification of Greendyke technique for fetal cell typing is described in which incubation time and quantities of antisera are reduced without affecting the sensitivity of the test. ...

journal_title：Transfusion

authors： Bryant NJ,Shanahan LS,Sutton DM

更新日期：1979-03-01 00:00:00

abstract：:The potassium load of transfused blood must be minimized. We have compared the total plasma potassium content of units of CPD-preserved stored whole blood (SWB), stored packed cells (SPC), and packed cells prepared from stored whole blood (WB-PC). Plasma potassium concentrations, unit weights, and hematocrits of 20 un...

journal_title：Transfusion

authors： Michael JM,Dorner I,Bruns D,Ladenson JH,Sherman LA

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:The potential hemostatic effect of infusible platelet membranes (IPM; Cyplex, Cypress Bioscience) prepared from outdated human platelets is investigated. STUDY DESIGN AND METHODS:Increasing concentrations of IPM were added to blood samples anticoagulated with low-molecular-weight heparin, in which platelets...

journal_title：Transfusion

authors： Galán AM,Bozzo J,Hernández MR,Pino M,Reverter JC,Mazzara R,Escolar G,Ordinas A

更新日期：2000-09-01 00:00:00

abstract：:Implementation of routine blood donor screening using anti-hepatitis C virus (HCV) enzyme immunoassay (EIA) has resulted in an urgent need for well-characterized supplemental assays to confirm the presence of HCV antibodies. A comparative study of four commercially available supplemental assays is reported here: first...

journal_title：Transfusion

authors： Evans CS,Tobler L,Polito A,Stewart J,Chien D,Wilber J,Quan S,Delaney S,Kuo G,Busch MP

更新日期：1992-06-01 00:00:00

abstract：:The research process is a balance between the inherent risks of new discoveries and the risks of research participant safety. Conflicts of interest, inherent to the research process, as well as those introduced by emerging cellular therapies, have the potential to compromise safety. The relationship of trust between t...

journal_title：Transfusion

authors： Yim R

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:A new generation of assays for the detection of human T-lymphotropic virus types I and II (HTLV-I/II) antibodies has been released. These assays incorporate HTLV-I- and HTLV-II-specific antigens, and some are based on new assay principles. Comparative evaluation data that include these new as well as previou...

journal_title：Transfusion

authors： Andersson S,Thorstensson R,Ramirez KG,Krook A,von Sydow M,Dias F,Biberfeld G

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Photochemical pathogen inactivation treatment (PCT) of plasma components with amotosalen and UVA has been implemented in Europe. To establish a postapproval safety database, an active hemovigilance (HV) program utilizing an electronic data capture system (EDCS) was initiated. STUDY DESIGN AND METHODS:The re...

journal_title：Transfusion

authors： Cazenave JP,Waller C,Kientz D,Mendel I,Lin L,Jacquet M,Propst M,Liu W,Corash L,Sundin D,Defoin L,Messe N,Osselaer JC

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:JMH is a high-frequency red cell blood group antigen that resides on a 76- to 80-kDa glycosylphosphatidylinositol-linked protein also known as CDw108. Antibodies with JMH specificity are often autoimmune and are usually, if not always, clinically benign. Some individuals with JMH-variant antigen produce allo...

journal_title：Transfusion

authors： Mudad R,Rao N,Issitt PD,Roy RB,Combs MR,Telen MJ

更新日期：1995-11-01 00:00:00

abstract：:After immunization with native human red cells and red cells infected with Plasmodium falciparum, mouse splenocytes were fused with a myeloma cell line to obtain hybridomas. Among the antibodies specific for blood group antigens, four antibodies (iB3C4, F12, MR432, and iB4) directed against epitopes related to the Rh ...

journal_title：Transfusion

authors： Rouger P,Edelman L

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Anti-Tc(a) detects a high-incidence antigen in the Cromer blood group system. Cromer system antibodies have not usually been associated with hemolytic transfusion reactions or hemolytic disease of the newborn. CASE REPORT:Anti-Tc(a) (initially identified in the patient's serum in 1982) was not detected when...

journal_title：Transfusion

authors： Kowalski MA,Pierce SR,Edwards RL,Ethirajan S,Ryan K,Livergood MP

更新日期：1999-09-01 00:00:00