[Intensity modulated radiotherapy treatment for prostate cancer, first experience in Chile].

Abstract:

BACKGROUND:Intensity modulated radiotherapy (IMRT) is an important step forward in cancer treatment. AIM:To report the first experience in Chile with IMRT for prostate cancer and compare the results obtained with different doses. PATIENTS AND METHODS:From January 1997 through June 2008, 156 patients with a mean age of 70 years, were treated with radiotherapy and 121 with IMRT. Patients were staged according to American Commission on Cancer Staging. Their biochemical relapse risk was classified according to the MD Anderson classification. Patients were routinely checked during and after therapy to evaluate side effects and relapse. RESULTS:Median follow up was 46 months (4-120). Overall five years survival was 85%. Biochemical relapse free five years survival for low, intermediate and high risk patients was 100, 82 and 70%, respectively. Biochemical relapse free survival for patients receiving radiotherapy doses over 76 Gy was 83%, compared to 30% for those receiving lower doses (p < 0.05). Urinary and gastrointestinal acute toxicity was low in 80% and 90% of patients respectively. Late toxicity developed in less than 3% of patients. CONCLUSIONS:IMRT for prostate cancer is readily available and safe in Chile. Biochemical disease free survival improved with higher doses with low toxicity rates.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Besa D C P,Rosso A R,Bustos C M,Borghero Y,Trucco B C,Mac-Namara H M

doi

/S0034-98872011001100009

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

1451-7

issue

11

eissn

0034-9887

issn

0717-6163

pii

S0034-98872011001100009

journal_volume

139

pub_type

杂志文章
  • [Istanbul declaration on organ trafficking and transplant tourism].

    abstract::This is a translation into Spanish, done by Mario Uribe, M.D., F.A.C.S., and authorized by the Conference Organization, of the official statements signed by The Transplantation Society, The International Society of Nephrology and the representatives who participated at a WHO sponsored Conference held in Istambul, Turk...

    journal_title:Revista medica de Chile

    pub_type: 共识发展会议,杂志文章

    doi:10.4067/S0034-98872009000800019

    authors: Transplantation Society.,International Society of Nephrology.

    更新日期:2009-08-01 00:00:00

  • [Long-term results of mitral valve repair for ischemic mitral insufficiency].

    abstract:BACKGROUND:The preferred treatment for ischemic mitral insufficiency is mitral valve repair with a prosthetic ring, because it does not deteriorate left ventricular function, allowing better immediate and long-term results. AIM:To assess long-term results of mitral annuloplasty with a prosthetic ring for ischemic mitr...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872011001200003

    authors: Zalaquett S R,Flores A E,Cartajena de la M F,Bächler S P,Córdova A S,Becker R P,Morán V S,Irarrázabal Ll M,Muñoz C C,González F R

    更新日期:2011-12-01 00:00:00

  • [Epithelial lesions associated with gallbladder carcinoma. A methodical study of 32 cases].

    abstract::Using mapping techniques, 32 consecutive gallbladder carcinomas diagnosed in our department were studied. The defined lesions were dysplasia, carcinoma in situ and superficial spreading carcinoma. A total of 2257 lesions were recorded from 1072 inclusions. All the defined lesions were present in about 10% of all secti...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Roa I,Araya JC,Wistuba I,Villaseca M,de Aretxabala X,Busel D,Burgos L

    更新日期:1993-01-01 00:00:00

  • [Current management strategies for pulmonary hypertension in surgical patients].

    abstract::Pulmonary hypertension is a clinical condition with a low prevalence, but carries high morbidity and mortality. Important advances in the understanding of this disease and in its therapy have occurred. A particular scenario is pulmonary hypertension in patients undergoing non-cardiac as well as cardiac surgery. The ai...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:/S0034-98872010000400016

    authors: Fermandois C M,López B R,León S P,Lema F G

    更新日期:2010-04-01 00:00:00

  • [Proportion of patients with heart failure in a specialized clinic eligible for novel therapies].

    abstract:BACKGROUND:Pharmacological treatment improves survival in patients with heart failure with reduced ejection fraction. The use of sacubutril/valsartan and ivabradine has been recently approved and incorporated in the latest guidelines. AIM:To identify candidates eligible for these therapies among patients treated in a ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872019000300330

    authors: Rossel V,Duarte M,Muñoz P,Bravo C,Bobadilla G,Verdugo F,Guardamagna C

    更新日期:2019-03-01 00:00:00

  • [Efficacy of two gene species in the serological diagnosis of Borrelia burgdorferi infections].

    abstract:BACKGROUND:There is phenotypic and genetic variability among the species Borrelia burgdorferi that produces Lyme disease. Three gene species and seven serotypes have been defined. AIM:To study the efficacy of two gene species in the serological diagnosis of Borrelia burgdorferi infections in Granada, Spain. MATERIAL ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Gutiérrez J,Núñez F,Piédrola G,Maroto C

    更新日期:1998-06-01 00:00:00

  • [Renal scintigraphy with captopril in the evaluation of renovascular hypertension].

    abstract::The administration of an angiotensin-converting enzyme (ACE) inhibitor transitorily reduces the GFR in a kidney with renal artery stenosis, effect that can be ascertained with scintigraphic studies using ACE inhibitors. We evaluated the clinical usefulness of captopril renography (CR) in the diagnosis of renovascular ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Orellana P,Jalil R,Valdés F,Fava M,Olea E,Fernández MS,Valdés G,Contreras O,Fontbote C

    更新日期:1993-07-01 00:00:00

  • [Controversies in massive pulmonary embolism].

    abstract::Massive pulmonary embolism (PE) is associated with high mortality. There is still a broad assortment of severity classifications for patients with PE, which affects the choice of therapies to use. The main clinical criteria for defining a PE as massive is systemic arterial hypotension, which depends on the extent of v...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/S0034-98872013000400010

    authors: Mercado M,Aizman A,Andresen M

    更新日期:2013-04-01 00:00:00

  • [Mycotic aneurysms and multiple peripheral embolisms in a patient with infectious endocarditis].

    abstract::Sepsis from an infected cardiac valve can lead to bacterial seeding and destruction of the arterial wall with formation of a mycotic aneurysm. The natural history of these lesions is the rupture. We report the case of a 20 year old female who was admitted to our institution with massive mitral regurgitation and emboli...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Mertens R,Krämer A,Valdés F,Garayar B,Irarrázaval M

    更新日期:1997-06-01 00:00:00

  • [Association between chronic periodontitis and rheumatoid arthritis. A systematic review].

    abstract::Rheumatoid arthritis (RA) and chronic periodontitis (CP) may be related due to a bidirectional etiology. The evidence shows that CP could alter the clinical course of RA. We performed a systematic search to determine if CP alters the morbidity of RA, analyzing its clinical and molecular aspects. Of 552 initial article...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872019000600762

    authors: Wen S,Beltrán V,Chaparro A,Espinoza F,Riedemann JP

    更新日期:2019-06-01 00:00:00

  • [Effectiveness of oral hypoglycemic drugs in the metabolic control of patients with gestational diabetes].

    abstract::Gestational Diabetes is characterized by different degrees of glucose intolerance that produce a series of fetal and perinatal alterations. During many years, in those cases of gestational diabetes that did not respond to nutritional interventions, the use of insulin was a proven treatment to achieve metabolic control...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:/S0034-98872008000700015

    authors: Valdés R E,Soto-Chacón E,Lahsen M R,Barrera H C,Candía P P

    更新日期:2008-07-01 00:00:00

  • [Evaluation of oral anticoagulation with rivaroxaban, in patients with new onset non valvular atrial fibrillation].

    abstract:BACKGROUND:Atrial fibrillation (AF) generates a hypercoagulable state with an increased thrombin generation and raised levels of thrombin-antithrombin complexes, which results in a high risk of stroke and thromboembolism. AIM:To evaluate the anticoagulant effect of rivaroxaban by anti-Xa factor activity and its correl...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872016000900002

    authors: Neira V,Corbalán R,Pereira J,Panes O,Garayar B,Aizman A,Llevaneras S,Villarroel L

    更新日期:2016-09-01 00:00:00

  • [Application of a system of serological surveillance of Chagas disease in a region of high chagasic endemia. I. Prevalence of Trypanosoma cruzi infection in Salamanca].

    abstract::A serologic study for prevalence of Chagas infection was performed in Salamanca, Northern Chile. Indirect immunofluorescence and indirect hemagglutination reactions were used in samples from 1529 females and 698 males representing 10% of the population. A total of 499 positive results were obtained. The incidence of i...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Lorca M,Reyes V,Muñoz P,Tassara R,Canales M,Mercado R,Atías A

    更新日期:1991-04-01 00:00:00

  • [Characteristics of acute myocardial infarction in patients with diabetes mellitus].

    abstract::We analyzed retrospectively the clinical course and prognosis of 565 consecutive patients with acute myocardial infarction (AMI), 117 of them with a previous history of diabetes mellitus. Male/female ration was 7.9/2.1 in non diabetics and 7.0/3.0 in diabetics (p < 0.03). Incidence of hypertension and hyperlipidemia w...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Kunstmann S,Corbalán R,Rodríguez JA,Casanegra P,Varela ML

    更新日期:1993-06-01 00:00:00

  • [Ménétrier disease. Report of one case].

    abstract:BACKGROUND:Ménétrier disease is a rare disorder of the stomach, characterized by giant hypertrophic folds that usually involve the gastric body and fundus, associated to hypoalbuminemia due to serum protein loss across the gastric mucosa. We report a 55-years-old male presenting with abdominal pain, vomiting, weight lo...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872012000900011

    authors: Gompertz M,Montenegro C,Bufadel ME,Defilippi C,Castillo J,Morales C

    更新日期:2012-09-01 00:00:00

  • [Adrenal hyperplasia of late onset: optimization of therapy by measuring the circadian variation of serum 17-OH-progesterone].

    abstract::A 19 yr-old female patient with the diagnosis of late onset adrenal hyperplasia was treated since age 15 with different glucocorticoid preparations and dosage schedules plus spironolactone. In spite of a very good response in terms of amelioration of their hirsutism she experienced cushingoid manifestations associated...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Contreras P,Rojas A,Vega I

    更新日期:1989-06-01 00:00:00

  • [Echotomographic findings in gastric cancer].

    abstract::Echotomographic studies were performed in 163 patients with gastric cancer from 1984 to 1990. The technical aspects of the examination and the images obtained in different lesions are described. Emphasis is placed on local or diffuse wall infiltration, ulcerations, vegetations or stenotic lesions. Consideration of the...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Arroyo A,Mánquez P,Traipe E

    更新日期:1992-01-01 00:00:00

  • [Measurement of the carbon footprint at a regional hospital].

    abstract:BACKGROUND:Measuring the carbon footprint (CF) makes it possible to estimate the contribution of clinical activity to global warming. AIM:To measure the emitter components of CO2 equivalents (CO2e) at the Hospital Base, Puerto Montt (HBPM). MATERIAL AND METHODS:Descriptive study with data collected retrospectively be...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872018001201384

    authors: Balkenhol M,Castillo A,Soto M,Feijoo M,Merino W

    更新日期:2018-12-01 00:00:00

  • [Prevalence of obesity among Chilean women in childbearing ages].

    abstract:BACKGROUND:Women in childbearing ages (WCBA) represent a strategic intervention group to reverse the global trend of increasing obesity. AIM:To conduct a review of studies reporting obesity prevalence in WCBA in Chile in the last 25 years. MATERIAL AND METHODS:To describe obesity prevalence, we used three approaches,...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/S0034-98872014001100011

    authors: Araya B M,Padilla O,Garmendia ML,Atalah E,Uauy R

    更新日期:2014-11-01 00:00:00

  • [Glucotoxicity and lipotoxicity: factors in the pathogenesis and evolution of type 2 diabetes].

    abstract::Glucose toxicity refers to the structural and functional damage in the beta cells and target tissues of insulin, caused by chronic hyperglycemia. These alterations cause a lower hormonal secretion and action (insulin resistance). Lipid toxicity refers to the damage caused by persistently high free fatty acid levels, a...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Durruty P,García de los Ríos M

    更新日期:2001-06-01 00:00:00

  • [Response rates to first-line treatment in eligible patients to autologous stem transplantation in Chile].

    abstract::Background The treatment of choice of newly diagnosed multiple myeloma (NDMM) is an induction with proteasome inhibitors followed autologous stem cell transplantation (HSCT). Since 2013, the treatment of these patients in the public system is based on CTD (cyclophosphamide, thalidomide, and dexamethasone). Aim To eval...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,多中心研究

    doi:10.4067/S0034-98872019001201561

    authors: Peña C,Rojas-Vallejos J,Espinoza M,Donoso J,Soto P,Cardemil D,Aranda S,Contreras C,Vergara CG,LA Rocca G,Osorio R,López-Vidal H,Chandía M,Rojas C

    更新日期:2019-12-01 00:00:00

  • [An analysis of authorship in articles published in Revista Médica de Chile].

    abstract:BACKGROUND:Multiauthorship and unjustified authorship have been documented in journals with wide international circulation but this has not been thoroughly studied in journals from developing countries. Revista Médica de Chile is published in Spanish and it contains about 40% of the clinical and biomedical manuscripts ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Jacard M,Herskovic V,Hernández I,Reyes H

    更新日期:2002-12-01 00:00:00

  • [Measurement of 17 OH progesterone in blood in Chilean newborns: antecedents for implementing a grogram for the neonatal detection of congenital adrenal hyperplasia].

    abstract:BACKGROUND:The early diagnosis and therapy of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency can prevent adrenal crises and erroneous gender assignment in affected newborns. To achieve this goal neonatal mass-screening programs have been developed, measuring blood 17 alpha-hydroxyprogesterone (17...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Cattani A,Reyes ML,Azócar M,Soto J,Romeo E,Valdivia L,Poggi H,Foradori A

    更新日期:2000-10-01 00:00:00

  • [Delayed hemolytic reaction to transfusion in sickle cell anemia. Report of one case].

    abstract::Sickle cell anemia was a rare disease in Chile, especially in adults, however the recent immigration wave from Haiti is changing this scenario. We report a 29 year old black female from Haiti with a non-disclosed history of sickle cell anemia. She was transfused with two units of red blood cells, found unconscious and...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872018001101347

    authors: Moya F,Rivera M,Araya F,Donoso J,Sandoval P,Varas P

    更新日期:2018-11-01 00:00:00

  • [Tuberculosis and diabetes mellitus: a longitudinal-retrospective study in a teaching hospital].

    abstract::We analyzed 1529 diabetic patients seen between 1959 and 1982 at a teaching hospital in Concepción, Chile. 116 of them were insulin dependent diabetics. Gestational diabetes was excluded. The 10 year actuarial risk of acquiring tuberculosis was 24.2% for insulin-dependent diabetics and 4.8% for the rest (p less than 0...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Olmos P,Donoso J,Rojas N,Landeros P,Schurmann R,Retamal G,Meza M,Martinez C

    更新日期:1989-09-01 00:00:00

  • [Factors associated with the immune response to hepatitis B vaccine in Brazilian hemodialysis patients].

    abstract:BACKGROUND:Patients on chronic hemodialysis have a lower immune response to vaccination against hepatitis B virus (HBV) than the general population. AIM:To identify factors that may interfere with immunization against hepatitis B virus (HBV) in Brazilian hemodialysis patients and analyze the evolution of the level of ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872012000700008

    authors: Pereira ZT,Mendoza-Sassi RA

    更新日期:2012-07-01 00:00:00

  • [Influence of personality and learning styles in the choice of medical specialty].

    abstract:BACKGROUND:Several studies indicate that doctors who work in the same area of the medical profession tend to behave somehow similarly. Thus, it has been suggested that personality relates to the medical specialty choice. However, it is not known whether people self-select into the medical specialties according to their...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872005001000008

    authors: Bitran M,Zúñiga D,Lafuente M,Viviani P,Mena B

    更新日期:2005-10-01 00:00:00

  • [Markers of HIV infection in prostitutes: analysis of preventive and risk factors].

    abstract::We studied 501 prostitutes from the northern and eastern areas of Santiago in november and december, 1987. HIV infection was studied by the HIV antibody and also by HIV antigen. At that time no positive reactors were found. Prostitutes from the northern area were older, of a lower socioeconomic background and less pro...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Quero MS,Suárez M,Uribe J,Cerda P,Espoz H,Arroyave R

    更新日期:1989-06-01 00:00:00

  • [Dr. Alfonso María Thévenot. 2. In Chile and in France].

    abstract::This French physician was hired by the Chilean government in 1867. He was a brilliant surgeon who made significant contributions to Chilean medicine. He returned to France in 1873, where he had a successful career as a professor of obstetrics. ...

    journal_title:Revista medica de Chile

    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Costa-Casaretto C

    更新日期:1990-11-01 00:00:00

  • [Aortic valve multiple papillary fibroelastoma complicated with a cerebrovascular accident: Report of one case].

    abstract::The echocardiographic identification of cardiac tumors as cause of embolic episodes is infrequent, and the finding of multiple papillary fibroelastoma is even less common. We report a 70 years old female with a history of a rheumatic mitral valve lesion, subjected to a commissurotomy in 1970. She was admitted with a c...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Córdova S,Zalaquett R,Chuaqui B,Casanegra P,Chamorro G

    更新日期:2001-09-01 00:00:00