Abstract:
:There is a growing focus in the medical community on de-escalating medical treatments where appropriate; however, specific efforts to reduce medication burden in patients with polypharmacy has largely been targeted toward adult populations. Polypharmacy increases the risk of adverse drug reactions in children, and that risk may be further increased by the use of off-label drugs. The paediatric prescribing community should explore pharmacovigilance strategies and deprescription initiatives that prioritize patients with polypharmacy. Currently, best practices may be extrapolated from the adult literature, including medication review algorithms and patient education tools. Enhancing access to nonpharmacological modalities to address child and youth mental health may mitigate psychotropic polypharmacy. The aim of these initiatives should be to improve patient outcomes and experiences by avoiding adverse drug events and drug-drug interactions.
journal_name
Paediatr Child Healthjournal_title
Paediatrics & child healthauthors
Bogler O,Roth D,Feinstein J,Strzelecki M,Seto W,Cohen Edoi
10.1093/pch/pxy188subject
Has Abstractpub_date
2019-08-01 00:00:00pages
303-305issue
5eissn
1205-7088issn
1918-1485pii
pxy188journal_volume
24pub_type
杂志文章abstract:BACKGROUND:Many intervention studies typically require data from several centres to ensure adequate power. The usual intention is to pool data after testing for heterogeneity. Sites that differ in sample characteristics may, on the one hand, complicate the assessment of the intervention, but on the other hand, they may...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/8.7.433
更新日期:2003-09-01 00:00:00
abstract:Objective:To examine changes in the awareness, use, feasibility, and barriers associated with the Canadian Physical Activity and Sedentary Behaviour Guidelines for Children and Youth ages 0-17 years in a sample of Canadian paediatricians, and to assess tools/resources developed by the Canadian Paediatric Society (CPS)....
journal_title:Paediatrics & child health
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doi:10.1093/pch/pxx006
更新日期:2017-03-01 00:00:00
abstract::The present statement reviews the evidence for universal newborn hearing screening (UNHS). A systematic review of the literature was conducted using Medline and using search dates from 1996 to the third week of August 2009. The following search terms were used: neonatal screening AND hearing loss AND hearing disorders...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/16.5.301
更新日期:2011-05-01 00:00:00
abstract::Sepsis is a systemic inflammatory response to suspected or proven infection. Given its importance in terms of morbidity and mortality, a number of initiatives by several professional societies in recent years have led to the development of guidelines for the recognition and timely management of sepsis. The principal e...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxz178
更新日期:2020-11-02 00:00:00
abstract:Objective:To determine if treatment failure varies based on ROME III classification and adherence to guideline congruent therapy among children diagnosed in an emergency department with functional constipation. Methods:Children aged 1 month to 18 years who were diagnosed with constipation in a paediatric emergency dep...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxy121
更新日期:2019-06-01 00:00:00
abstract::Respiratory syncytial virus (RSV) is recognized as an important cause of childhood morbidity and mortality. Vaccine development has been challenging in young infants and has required the advent of molecular technologies to optimize the safety profile, while maintaining immunogenicity of live-attenuated vaccines. Prote...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/8.10.605
更新日期:2003-12-01 00:00:00
abstract:OBJECTIVE:To assist in the diagnosis of retinopathy of prematurity (ROP) to facilitate treatment in a timely manner to help prevent blindness. DATA SOURCES:Systematic review using MEDLINE including the following key words, "retinopathy of prematurity", "retrolental fibroplasia", "blind", "blindness", "vision screening...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract:Objective:School-based vaccination programs can be a source of distress for many students due to the pain from the needle injection and related fears. We created a multifaceted Knowledge Translation (KT) intervention to address vaccination and pain, fear, and fainting called The CARD™ System. The objectives were to doc...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxz018
更新日期:2019-04-01 00:00:00
abstract::Adolescents who suffer from chronic pain also report complex syndrome-associated disability and distress that can detrimentally affect the quality of their lives and the lives of their family members. Over the past 10 years, there have been significant developments in both methods of assessment and in treatment progra...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/12.2.117
更新日期:2007-02-01 00:00:00
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journal_title:Paediatrics & child health
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doi:10.1093/pch/13.6.499
更新日期:2008-07-01 00:00:00
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journal_title:Paediatrics & child health
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更新日期:2002-07-01 00:00:00
abstract::Nutrition for Healthy Term Infants is the new national statement on nutrition for infants from birth to 24 months, developed collaboratively by the Canadian Paediatric Society, Dietitians of Canada and Health Canada.The document summarizes the existing scientific literature on infant nutrition and presents principles ...
journal_title:Paediatrics & child health
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doi:10.1093/pch/3.2.109
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVE:To describe an approach to history, physical examination and investigation for the developmentally delayed child. METHODS:A review of electronic databases from 1997 to 2001 was done searching for articles relating to the approach to or investigations of children with developmental delay. Five studies, includ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/8.1.16
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:All Canadian jurisdictions require certain professionals to report suspected or observed child maltreatment. The present study examined the types of maltreatment, level of harm and child functioning issues (controlling for family socioeconomic status, age and sex of the child) reported by health care and non...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/15.8.e25
更新日期:2010-10-01 00:00:00
abstract::Arthropod-borne diseases do not occur commonly in Canada. Nevertheless, Canadians run the risk of contracting certain infections within the country during arthropod season, as well as when travelling abroad. Therefore, it is important that clinicians are aware of the possible occurrence of arthropod-borne diseases, an...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/5.4.206
更新日期:2000-05-01 00:00:00
abstract:Introduction:In June 2012, the government of Canada severely restricted the scope of the Interim Federal Health Program that had hitherto provided coverage for the health care needs of refugee claimants. The Quebec government decided to supplement coverage via the provincial health program. Despite this, we hypothesize...
journal_title:Paediatrics & child health
pub_type: 杂志文章
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更新日期:2017-11-01 00:00:00
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journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/10.5.269
更新日期:2005-05-01 00:00:00
abstract::Paediatric restless legs syndrome (RLS) treatment is important because RLS's associated sleep disturbance causes significant developmental-behavioural morbidity and impacts family well-being. RLS is associated with brain iron insufficiency and dopaminergic dysfunction. Diagnosis requires fulfillment of diagnostic crit...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/17.4.193
更新日期:2012-04-01 00:00:00
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journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/5.6.329
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:To determine whether reminder notices would improve the timeliness of toddler-age vaccinations. DESIGN:Prospective, randomized, controlled trial. POPULATION STUDIED:Two convenience cohorts of 320 children due to receive either measles-mumps-rubella (MMR) vaccine (at 12 months of age) or diphtheria-pertussis...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
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journal_title:Paediatrics & child health
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journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxx126
更新日期:2018-02-01 00:00:00
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journal_title:Paediatrics & child health
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更新日期:2014-04-01 00:00:00
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journal_title:Paediatrics & child health
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更新日期:2012-11-01 00:00:00
abstract:OBJECTIVES:To describe the clinical features, diagnosis, treatment and outcome of children with Kawasaki disease (KD) treated at a large tertiary care Canadian paediatric hospital and to try to identify correlations between clinical features and the development of coronary artery abnormalities. METHODS:The charts of 1...
journal_title:Paediatrics & child health
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更新日期:2004-09-01 00:00:00
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journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/15.7.e19
更新日期:2010-09-01 00:00:00
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journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
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journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/17.5.251
更新日期:2012-05-01 00:00:00
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journal_title:Paediatrics & child health
pub_type: 杂志文章
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更新日期:2008-12-01 00:00:00
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journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxy171
更新日期:2019-06-01 00:00:00