Abstract：
PURPOSE:Postoperative spinal cord injury is a devastating complication after aortic arch replacement. The purpose of this study was to determine the predictors of this complication. METHODS:A group of 254 consecutive patients undergoing aortic arch replacement via median sternotomy, with (n = 78) or without (n = 176) extended replacement of the upper descending aorta, were included in a risk analysis. The frozen elephant trunk technique was used in 46 patients. The patients' atherothrombotic lesions (extensive intimal thickening of > 4 mm) were identified from computed tomography images. RESULTS:Complete paraplegia (n = 7) and incomplete paraparesis (n = 4) occurred immediately after the operation (permanent spinal cord injury rate, 1.97%; transient spinal cord injury rate, 2.36%). A multivariable logistic regression analysis identified the use of the frozen elephant trunk technique (odds ratio 36.3), previous repair of thoracoabdominal aorta or descending aorta (odds ratio 29.4), proximal atherothrombotic aorta (odds ratio 9.6), chronic obstructive lung disease (odds ratio 7.1) and old age (odds ratio 1.1) as predictors of spinal cord injury (p < 0.0001, area under curve 0.93). CONCLUSIONS:Spinal cord injury occurs with a non-negligible incidence following aortic arch replacement. The full objective assessment of the morphology of the whole aorta and the recognition of the risk factors are mandatory.
journal_name
Surg Todayjournal_title
Surgery todayauthors
Tokuda Y,Fujimoto K,Narita Y,Mutsuga M,Terazawa S,Ito H,Matsumura Y,Uchida W,Munakata H,Ashida S,Ono T,Nishi T,Yano D,Ishida S,Kuwabara F,Akita T,Usui Adoi
10.1007/s00595-019-01853-2subject
Has Abstractpub_date
2020-02-01 00:00:00pages
106-113issue
2eissn
0941-1291issn
1436-2813pii
10.1007/s00595-019-01853-2journal_volume
50pub_type
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