Autoimmune T cells lured to a FASL web of death by MSCs.

Abstract:

:Achieving immune tolerance through cell transplantation is a promising approach for treating autoimmune disease. In this issue of Cell Stem Cell, Akiyama et al. (2012) demonstrate that human and mouse mesenchymal stem cells can induce immune suppression by attracting and killing autoreactive T cells, which stimulates TGFb production by macrophages and generates regulatory T cells.

journal_name

Cell Stem Cell

journal_title

Cell stem cell

authors

Murphy WJ,Nolta JA

doi

10.1016/j.stem.2012.04.013

subject

Has Abstract

pub_date

2012-05-04 00:00:00

pages

485-7

issue

5

eissn

1934-5909

issn

1875-9777

pii

S1934-5909(12)00179-8

journal_volume

10

pub_type

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