Towards integrating personalized feedback research into clinical practice: Development of the Trier Treatment Navigator (TTN).

Abstract:

:In this study, a computer-based feedback, decision and clinical problem-solving system for clinical practice will be described - the Trier Treatment Navigator (TTN). The paper deals with the underlying research concepts related to personalized pre-treatment recommendations for drop-out risk and optimal treatment strategy selection as well as personalized adaptive recommendations during treatment. The development sample consisted of 1234 patients treated with cognitive behavioral therapy (CBT). Modern statistical machine learning techniques were used to develop personalized recommendations. Drop-out analyses resulted in seven significant predictors explaining 12.0% of variance. The prediction of optimal treatment strategies resulted in differential prediction models substantially improving effect sizes and reliable improvement rates. The dynamic failure boundary reliably identified patients with a higher risk for no improvement or deterioration and indicated the usage of clinical problem-solving tools in risk areas. The probability to be reliably improved for patients identified as at risk for treatment failure was about half of the probability for other patients (35% vs. 62.15%; χ2df=1 = 82.77, p < .001). Results related to the computer-based feedback system are discussed with regard to the implication for clinical applications as well as clinical training and future research possibilities.

journal_name

Behav Res Ther

authors

Lutz W,Rubel JA,Schwartz B,Schilling V,Deisenhofer AK

doi

10.1016/j.brat.2019.103438

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

103438

eissn

0005-7967

issn

1873-622X

pii

S0005-7967(19)30124-X

journal_volume

120

pub_type

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