Rate-responsive pacing and atrial high rate episodes in cardiac resynchronization therapy patients: Is low heart rate the key?

abstract：BACKGROUND:In patients with atrial fibrillation (AF), despite adequate anticoagulation, ischemic stroke (IS) is an uncommon yet concerning occurrence. HYPOTHESIS:Specific laboratory parameters may affect the efficacy of warfarin despite therapeutic international normalized ratio (INR) in patient with AF who present wi...

journal_title：Clinical cardiology

authors： Aachi RV,Birnbaum LA,Topel CH,Seifi A,Hafeez S,Behrouz R

更新日期：2017-12-01 00:00:00

abstract：:Lipoprotein(a) [Lp(a)] is independently associated with atherosclerotic cardiovascular disease and calcific aortic valve stenosis. Elevated Lp(a) affects approximately one in five individuals and meaningfully contributes to the residual cardiovascular risk in individuals with otherwise well-controlled risk factors. Wi...

journal_title：Clinical cardiology

authors： Berman AN,Biery DW,Ginder C,Hulme OL,Marcusa D,Leiva O,Wu WY,Singh A,Divakaran S,Hainer J,Turchin A,Januzzi JL,Natarajan P,Cannon CP,Di Carli MF,Bhatt DL,Blankstein R

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Electronic health record systems (EHR) are expected to facilitate higher quality patient care; however, studies evaluating EHR effectiveness in improving care have yielded mixed results. HYPOTHESIS:Implementation of a performance improvement system in outpatient practices with EHR may better demonstrate the...

journal_title：Clinical cardiology

authors： Walsh MN,Albert NM,Curtis AB,Gheorghiade M,Heywood JT,Liu Y,Mehra MR,O'Connor CM,Reynolds D,Yancy CW,Fonarow GC

更新日期：2012-03-01 00:00:00

abstract：:The severity and site of hypertrophy is important in determining the clinical picture and the natural history of hypertrophic cardiomyopathy (HCM). We evaluated left ventricular hypertrophy by means of two-dimensional echocardiographic score and score index, and correlated these findings with symptoms, electrovector-c...

journal_title：Clinical cardiology

authors： Melacini P,Fasoli G,Canciani B,Buja G,Mammola C,Volta SD

更新日期：1989-08-01 00:00:00

abstract：:Warfarin and other 4-hydroxycoumarins are effective antithrombotic agents. They affect four blood coagulation proteins that act sequentially to produce thrombin. Coumarin therapy decreases the biological activity of these proteins, and therefore decreases the rate at which blood clots. As the mechanism by which these ...

journal_title：Clinical cardiology

authors： Suttie JW

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Patients with acute myocardial infarction (AMI) and nonobstructive coronary artery disease (nonobCAD) may be perceived to be at lower risk for cardiac events, relative to those with obstructive CAD (obCAD), and thus less likely to receive optimal preventive medications in the year following AMI. HYPOTHESIS:...

journal_title：Clinical cardiology

authors： Pitts R,Daugherty SL,Tang F,Jones P,Ho PM,Tsai TT,Spertus J,Maddox TM

更新日期：2017-06-01 00:00:00

abstract：:The effects of heparin were studied in a group of 42 patients with preinfarction angina (PA) and acute myocardial infarction (AMI) whose plasma fibrinogen was increased. Plasma fibrinogen was measured by the turbidimetric method in timol turbidimetric units. Statistically significant results proved that heparin reduce...

journal_title：Clinical cardiology

authors： Ruggiero HA,Castellanos H,Caprissi LF,de Caprissi ES,Ruggiero LH

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:Intravenous inotropic intervention in congestive heart failure is generally associated with a poor prognosis and is largely used as a "bridge" to mechanical support or heart transplantation. HYPOTHESIS:We hypothesized that the inotropic support afforded by dobutamine may serve as a bridge to the introductio...

journal_title：Clinical cardiology

authors： Levine TB,Levine AB,Elliott WG,Narins B,Stomel RJ

更新日期：2001-03-01 00:00:00

abstract：:We evaluated the electrophysiological parameters before and after the intravenous infusion of diazepam (0.2 mg/kg) in 20 cardiac patients to investigate the drug's antiarrhythmic effect. Diazepam did not significantly change the arterial pressure. After the intravenous infusion of diazepam, the sinus cycle length sign...

journal_title：Clinical cardiology

authors： Kumagai K,Yamanouchi Y,Matsuo K,Tashiro N,Hiroki T,Arakawa K

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:An acute-phase response in patients with acute myocardial infarction could contribute to the development of anemia. HYPOTHESIS:An association may exist between symptom duration, hemoglobin (Hb) concentration and serum C-reactive protein (CRP) values in patients presenting to an emergency department (ED) wit...

journal_title：Clinical cardiology

authors： Shacham Y,Leshem-Rubinow E,Ben-Assa E,Roth A,Steinvil A

更新日期：2014-02-01 00:00:00

abstract：:A patient with reversible coronary artery spasm superimposed on fixed atherosclerotic coronary disease was treated with percutaneous transluminal angioplasty. The procedure successfully dilated the atherosclerotic lesion. However, 20 minutes later, the patient developed coronary artery spasm at the angioplasty site. S...

journal_title：Clinical cardiology

authors： Kern KB,Temkin LP,Fenster PE

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:While depressed left ventricular ejection fraction is clearly associated with poor long-term outcome in heart failure (HF), the effect of ejection fraction on short-term outcomes and resource utilization following hospitalization for HF remains unclear. HYPOTHESIS:We evaluated the independent effect of depr...

journal_title：Clinical cardiology

authors： Harjai KJ,Nunez E,Turgut T,Shah MP,Humphrey JS,Newman J,Cheirif J,Smart FW,Ventura HO

更新日期：1999-03-01 00:00:00

abstract：:In an open, multicenter extension of a short-term study, 159 patients with mild to moderate hypertension were treated with either ramipril monotherapy or a combination of ramipril and hydrochlorothiazide for up to 1 year. Patients started with either 5 mg ramipril once daily (responders in the short-term study) or a c...

journal_title：Clinical cardiology

authors： Heidbreder D,Froer KL,Bauer B,Cairns V,Breitstadt A,Bender N

更新日期：1993-01-01 00:00:00

abstract：:Diabetes mellitus is a significant condition, affecting major segments of all population groups studied. With the introduction of insulin and oral hypoglycemic therapy, together with better understanding of diet and weight control gained over the past half century, the primary causes of diabetic morbidity and mortalit...

journal_title：Clinical cardiology

authors： van Hoeven KH,Factor SM

更新日期：1989-11-01 00:00:00

abstract：:Individuals age >65 years represent the fastest-growing subpopulation in the United States. Although these individuals with the highest cardiovascular risk profile would be anticipated to be the most aggressively treated, paradoxically, treatment and baseline risk are inversely related. Presumably, the elderly populat...

journal_title：Clinical cardiology

authors： Wilmot KA,Khan A,Krishnan S,Eapen DJ,Sperling L

更新日期：2015-01-01 00:00:00

abstract：:Endothelial dysfunction is increasingly recognized as an early event in the pathogenesis of cardiovascular disease. This observation is consistent with the growing appreciation of the role of endothelium in maintaining cardiovascular health. Endothelial dysfunction and coronary artery disease are both linked to hypert...

journal_title：Clinical cardiology

authors： Pepine CJ

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to investigate the relationship between left atrial (LA) myocardial function and left ventricular (LV) diastolic dysfunction in subjects with preserved LV ejection fraction (LVEF). METHODS:The study included a group of 118 hypertensive patients and normal subjects. LV diastolic...

journal_title：Clinical cardiology

authors： Guan Z,Zhang D,Huang R,Zhang F,Wang Q,Guo S

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:The incidence of congestive heart failure (CHF) has not significantly declined over the past 50 years, and overall survival rates are low at 5 years following diagnosis. Numerous studies have shown low serum sodium to be a poor prognostic indicator of all cause mortality in CHF patients. HYPOTHESIS:The goal...

journal_title：Clinical cardiology

authors： DeWolfe A,Lopez B,Arcement LM,Hebert K

更新日期：2010-12-01 00:00:00

abstract：:Long-acting oral isosorbide dinitrate (ISDN) was replaced by Nitroderm TTS, and the utility of this drug in long-term treatment was assessed in 69 patients with angina pectoris. The frequency of attacks (p < 0.001) and the consumption of sublingual nitrate tablets (p < 0.01) were found to be significantly lower at 2 w...

journal_title：Clinical cardiology

authors： Hayashi H,Ito T,Matsubara T,Watanabe T,Kuzuya F,Mizuno Y,Sotohata I,Fujinami T,Toyama J,Yamada K

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Previously, the high maternal mortality in cardiac patients who became pregnant prompted the assertion: Women with an abnormal heart should not become pregnant. This long-standing notion needs to be revised today. HYPOTHESIS:The study was undertaken to ascertain the experience with a large series of pregnan...

journal_title：Clinical cardiology

authors： Avila WS,Rossi EG,Ramires JA,Grinberg M,Bortolotto MR,Zugaib M,da Luz PL

更新日期：2003-03-01 00:00:00

abstract：:Intracoronary (i.c.) thrombus is a frequent finding in patients with unstable angina (UA). Accordingly, thrombolytic treatment could be beneficial, as resolution of thrombus might result in increased delivery of blood flow to the ischemic regions. To test this hypothesis, we studied 13 patients with active UA and ST-s...

journal_title：Clinical cardiology

authors： Pozzati A,Bugiardini R,Ottani F,Morgagni GL,Puddu P

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Obesity can lead to increased oxidative stress which is one of the proposed mechanisms in the etiopathogenesis of takotsubo cardiomyopathy (TCM). HYPOTHESIS:The presence of obesity adversely impacts clinical outcomes in TCM patients. METHODS:We queried the Nationwide Inpatient Sample database (2010-2014) t...

journal_title：Clinical cardiology

authors： Desai R,Singh S,Baikpour M,Goyal H,Dhoble A,Deshmukh A,Kumar G,Sachdeva R

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Numerous evidence has suggested that either hypertension or atrial fibrillation (AF) is associated with systemic inflammation. Peroxisome proliferator-activated receptor-gamma (PPARgamma) has been proved to have anti-inflammatory effects and is implicated as a molecular pathway involved in many cardiovascula...

journal_title：Clinical cardiology

authors： Chen X,Bing Z,He J,Jiang L,Luo X,Su Y,Kan B,Huang D,Wei Y

更新日期：2009-06-01 00:00:00

abstract：:In addition to the role of the electrophysiological substrate, paroxysmal atrial fibrillation depends on the modulation of the atrial tissues by the autonomic nervous system. Experimentally, models of atrial fibrillation can be based on either adrenergic or vagal stimulations that provoke the arrhythmia by disturbing ...

journal_title：Clinical cardiology

authors： Coumel P

更新日期：1990-03-01 00:00:00

abstract：:Recently, a debate over the merits of statin therapy in primary prevention was published in the Wall Street Journal. The statin opponent claimed that statins should only be used in secondary prevention and never in any primary-prevention patients at risk for cardiovascular events. In this evidence-based rebuttal to th...

journal_title：Clinical cardiology

authors： Joshi PH,Chaudhari S,Blaha MJ,Jones SR,Martin SS,Post WS,Cannon CP,Fonarow GC,Wong ND,Amsterdam E,Hirshfeld JW,Blumenthal RS

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:ECG U-wave inversion can be classified as initial and terminal U inversion according to the phasic relationship to positive U-wave deflection. Initial U inversion is occasionally observed in hypertensive patients while terminal U inversion frequently appears during severe myocardial ischemia. HYPOTHESIS:The...

journal_title：Clinical cardiology

authors： Miwa K

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Assessment of patients with aortic stenosis (AS) and impaired left ventricular function remains challenging. Aortic valve calcium (AVC) scoring with computed tomography (CT) and fluoroscopy has been proposed as means of diagnosing and predicting outcomes in patients with severe AS. HYPOTHESIS:Severity of ao...

journal_title：Clinical cardiology

authors： Aksoy O,Cam A,Agarwal S,Ige M,Yousefzai R,Singh D,Griffin BP,Schoenhagen P,Kapadia SR,Tuzcu ME

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The prognostic ability of cardiac troponin I (TnI) has been demonstrated in general populations and among cardiovascular disease patients, but it has not been evaluated in cancer patients. HYPOTHESIS:This study assumes to have the prognostic ability of cardiac troponin in cancer patients visiting the emerge...

journal_title：Clinical cardiology

authors： Park SH,Kim T,Cha WC,Yoon H,Hwang SY,Shin TG,Sim MS,Jo I,Lee SH,Park HD,Choi JH

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:It is known that exercise-induced ST-segment elevation in lead V1 (V1-E) detects left anterior descending (LAD) stenosis. It was also postulated that ST elevation in aVR and simultaneous ST depression in V5 (aVR-E + V5-D) is a marker of ischemia due to significant stenosis of the LAD in patients with single-...

journal_title：Clinical cardiology

authors： Michaelides AP,Psomadaki ZD,Aigyptiadou MN,Richter DJ,Andrikopoulos GK,Dilaveris PE,Tsioufis K,Tousoulis D,Stefanadis C,Toutouzas PK

更新日期：2003-05-01 00:00:00

abstract：:Flecainide is reported to be effective in patients with paroxysmal tachycardias, but its effect on rapid ventricular response over accessory atrioventricular pathway during atrial fibrillation is not known. The influence of flecainide on various electrophysiological properties of the accessory pathway with special emp...

journal_title：Clinical cardiology

authors： Kappenberger LJ,Fromer MA,Shenasa M,Gloor HO

更新日期：1985-06-01 00:00:00