Risk factors for prolonged hospitalization after gynecologic laparoscopic surgery.

abstract：OBJECTIVE:This study aimed to validate the preoperative scoring system adopted in the Kanagawa Cancer Center (KCC) to stratify endometrial cancer patients for lymphadenectomy according to the risk of developing lymph node metastasis (LNM). METHODS:The records of 432 and 221 uterine cancer patients treated in the KCC a...

journal_title：Gynecologic oncology

authors： Imai K,Kato H,Katayama K,Nakanishi K,Kawano A,Iura A,Konnai K,Onose R,Hirahara F,Miyagi E

更新日期：2016-08-01 00:00:00

abstract：:Near-infrared (NIR) fluorescence imaging has emerged as a promising complimentary technique for intraoperative visualization of tumor tissue, lymph nodes and vital structures. In this review, the current applications and future opportunities of NIR fluorescence imaging in gynecologic oncology are summarized. Several s...

journal_title：Gynecologic oncology

authors： Handgraaf HJ,Verbeek FP,Tummers QR,Boogerd LS,van de Velde CJ,Vahrmeijer AL,Gaarenstroom KN

更新日期：2014-12-01 00:00:00

abstract：:Endometrial adenocarcinoma in young women below the age of 45 years and in a functioning endometrium is rare. We present the case of a 41-year-old woman, who without clinical risk factors, was found to have a focal well-differentiated endometrial adenocarcinoma in the background of a histologically secretory endometri...

journal_title：Gynecologic oncology

authors： Pai UL,Razi A,Selim MA,Petrelli M

更新日期：1993-05-01 00:00:00

abstract：:Uterine leiomyosarcoma is the most common type of uterine sarcoma. It is an extremely aggressive malignancy associated with a poor overall prognosis. Women affected may vary in age, but are most often diagnosed in their perimenopausal years. Presenting symptoms may be vague and mimic other benign uterine conditions. P...

journal_title：Gynecologic oncology

authors： Roberts ME,Aynardi JT,Chu CS

更新日期：2018-12-01 00:00:00

abstract：:Lymph node sampling is part of the FIGO staging of patients with ovarian carcinoma and is usually part of a meticulous second look operation. We analyzed the primary lymph node status of patients and compared this to the lymph node status at second look operation. From 3/86-3/91, 97 patients with epithelial ovarian tu...

journal_title：Gynecologic oncology

authors： Goldberg GL,Scheiner J,Friedman A,O'Hanlan KA,Davidson SA,Runowicz CD

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:The purpose was to explore whether health education on symptoms of ovarian cancer would aid in early detection, by examining the relationship between symptoms, coping strategies, and timing of presentation in patients with newly diagnosed ovarian cancer. METHODS:Eighty women were included. A questionnaire co...

journal_title：Gynecologic oncology

authors： Chan YM,Ng TY,Lee PW,Ngan HY,Wong LC

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy, feasibility and safety of image-based, inversely and adaptively planned high-dose rate interstitial brachytherapy (HDR-ISBT) to treat advanced primary or recurrent gynecologic malignancy in a single implant, three-consecutive-day regimen. METHODS:Clinical demographics and outcome da...

journal_title：Gynecologic oncology

authors： Hanania AN,Myers P,Yoder AK,Bulut A,Henry Yu Z,Eraj S,Bowers J,Bonnen MD,Echeverria A,Hall TR,Anderson ML,Ludwig M

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were twofold: to prospectively assess whether expressed intention to undergo prophylactic oophorectomy translated into uptake and to evaluate the psychological impact of the procedure in a sample of unaffected women with a strong family history of breast/ovarian cancer. METHODS:...

journal_title：Gynecologic oncology

authors： Tiller K,Meiser B,Butow P,Clifton M,Thewes B,Friedlander M,Tucker K

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVES:Lymph node status is an important prognostic factor in patients with squamous cell carcinoma (SCC) of the vulva. Complete inguinofemoral lymph node dissection (ILND) is accompanied by a high morbidity. Sentinel lymph node biopsy (SLNB) was established for less invasive lymph node (LN) staging. The aim of thi...

journal_title：Gynecologic oncology

authors： Johann S,Klaeser B,Krause T,Mueller MD

更新日期：2008-09-01 00:00:00

abstract：:A case of Stage IIIC primary ovarian leiomyosarcoma in a premenopausal woman with multiple recurrences alive and well 7 years after diagnosis is presented. In addition to the typical light microscopic, immunohistochemical, and electron microscopic features of ovarian leiomyosarcoma, the tumor was progesterone receptor...

journal_title：Gynecologic oncology

authors： Rasmussen CC,Skilling JS,Sorosky JI,Lager DJ,Buller RE

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:We previously reported that plasma levels of total lysophosphatidic acid (LPA) represented a potential biomarker for ovarian cancer and other gynecological cancers [1]. However, total LPA is composed of different LPA species with distinct fatty acid chains. The major objective of the current study, therefore,...

journal_title：Gynecologic oncology

authors： Shen Z,Wu M,Elson P,Kennedy AW,Belinson J,Casey G,Xu Y

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:Ovarian cancer is the leading cause of death from gynecologic malignancies in the Western world. Fibroblast growth factor receptor (FGFR) signaling has been implicated to play a role in ovarian tumorigenesis. Mutational activation of one member of this receptor family, FGFR2, is a frequent event in endometrio...

journal_title：Gynecologic oncology

authors： Byron SA,Gartside MG,Wellens CL,Goodfellow PJ,Birrer MJ,Campbell IG,Pollock PM

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:The current study was undertaken to determine if DNA ploidy is a useful prognostic variable for predicting recurrence in stage I endometrial cancer. For cancer of the endometrium, survival following recurrence may depend on a number of factors, including the pattern of recurrence and the response to second li...

journal_title：Gynecologic oncology

authors： Terada K,Mattson D,Goo D,Shimizu D

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:Preoperative identification of cervical stromal invasion in endometrial carcinoma is important to select patients for primary radical hysterectomy. The objective of this prospective implementation study was to assess if introduction of magnetic resonance imaging (MRI) in addition to the standardly applied end...

journal_title：Gynecologic oncology

authors： Haldorsen IS,Berg A,Werner HM,Magnussen IJ,Helland H,Salvesen OO,Trovik J,Salvesen HB

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:Mismatch repair (MMR) deficiency and Bethesda panel microsatellite instability (MSI) are increasingly analyzed to identify tumors that might benefit from immune checkpoint inhibitors, but tumor heterogeneity is a potential obstacle for such analyses. In ovarian cancer, data on intratumoral heterogeneity of MM...

journal_title：Gynecologic oncology

authors： Fraune C,Rosebrock J,Simon R,Hube-Magg C,Makrypidi-Fraune G,Kluth M,Büscheck F,Höflmayer D,Schmalfeldt B,Müller V,Wölber L,Witzel I,Paluchowski P,Wilke C,Heilenkötter U,von Leffern I,Clauditz TS,Wilczak W,Sauter G,S

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:Our objective was to determine the rate of BRCA1/2 deficiency in platinum-sensitive and platinum-resistant tumors from a cohort of unselect patients with advanced epithelial ovarian cancer (EOH). METHODS:BRCA1/2 mutation analysis was performed in 29 patients with platinum-sensitive EOC and 24 patients with p...

journal_title：Gynecologic oncology

authors： Dann RB,DeLoia JA,Timms KM,Zorn KK,Potter J,Flake DD 2nd,Lanchbury JS,Krivak TC

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study is to determine the impact of obesity on surgical and oncologic outcomes after primary debulking surgery (PDS) in advanced epithelial ovarian cancer (EOC). METHODS:Women with stage IIIC/IV EOC who underwent PDS with curative intent between 1/2/2003 and 12/30/2011 were included. Patient...

journal_title：Gynecologic oncology

authors： Kumar A,Bakkum-Gamez JN,Weaver AL,McGree ME,Cliby WA

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To determine the antitumor activity and toxicity profile of gemcitabine as second-line chemotherapy in patients with recurrent or persistent uterine leiomyosarcoma (LMS). METHODS:Intravenous gemcitabine was administered over 30 min at a dose of 1000 mg/m(2) on days 1, 8, 15, with cycles repeated every 28 day...

journal_title：Gynecologic oncology

authors： Look KY,Sandler A,Blessing JA,Lucci JA 3rd,Rose PG,Gynecologic Oncology Group (GOG) Study.

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of involved-field radiation therapy (IFRT) in patients with locoregionally confined recurrent or persistent epithelial ovarian cancer. METHODS:This study included patients with recurrent epithelial ovarian cancer eligible for IFRT either during diagnosis of the recurrence ...

journal_title：Gynecologic oncology

authors： Chang JS,Kim SW,Kim YJ,Kim JY,Park SY,Kim JH,Jang TK,Kim YB

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:Heredity is a major cause of ovarian cancer and during recent years the contribution from germline mismatch repair (MMR) gene mutations linked to Lynch syndrome has gradually been recognized. METHODS:We characterized clinical features, tumor morphology and mismatch repair defects in all ovarian cancers ident...

journal_title：Gynecologic oncology

authors： Ketabi Z,Bartuma K,Bernstein I,Malander S,Grönberg H,Björck E,Holck S,Nilbert M

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:Benefits of laparoscopy over laparotomy in patients with endometrial cancer (EC) are well known. As many patients with EC carry co-morbid conditions, surgery is exposing them to increased risk of complications. A review of the patients with EC recruited so far in a clinical trial comparing laparoscopy to lapa...

journal_title：Gynecologic oncology

authors： Tozzi R,Malur S,Koehler C,Schneider A

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:The objective was to identify the factors, if any, that may predict long-term results of CIN treatment and HPV clearance/persistence after locally excisional therapy. METHODS:A series of 252 women with CIN lesions treated by conization were subjected to sequential HPV detection by repeated PCR during the pro...

journal_title：Gynecologic oncology

authors： Costa S,De Simone P,Venturoli S,Cricca M,Zerbini ML,Musiani M,Terzano P,Santini D,Cristiani P,Syrjänen S,Syrjänen K

更新日期：2003-08-01 00:00:00

abstract：:Arterial thromboembolic disease almost always occurs in the setting of significant cardiovascular disease. Fewer than 10% of patients have no known etiology and only rarely is malignancy implicated. A review of the literature revealed only one prior report associated with a gynecologic malignancy, and this occurred in...

journal_title：Gynecologic oncology

authors： Minjarez DA,Delorit MA,Davidson SA

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:Comorbidities are known to increase endometrial cancer risk, but the separate and combined impact of these risk factors on endometrial cancer survival remains unclear. This study aimed to determine the associations between metabolic syndrome and its components with disease-free survival, overall survival, end...

journal_title：Gynecologic oncology

authors： Kokts-Porietis RL,McNeil J,Nelson G,Courneya KS,Cook LS,Friedenreich CM

更新日期：2020-09-01 00:00:00

abstract：:Clear cell carcinoma of the ovary accounts for 2 to 3% of all epithelial ovarian neoplasms. Patient profiles, pathological characteristics, and results of treatment are reviewed for 59 patients. The median age was 51. Disease extent at diagnosis was as follows: stage I, 18 patients (31%); stage II, 20 patients (34%); ...

journal_title：Gynecologic oncology

authors： Crozier MA,Copeland LJ,Silva EG,Gershenson DM,Stringer CA

更新日期：1989-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to examine the clinicopathologic correlates of T-regulatory (T(reg)) cell infiltration in serous ovarian cancers and to define gene signatures associated with high T(reg)s. METHODS:Tumor infiltrating T(reg) and cytotoxic T-cells (CTLs) were quantitated in 232 primary serous ov...

journal_title：Gynecologic oncology

authors： Barnett JC,Bean SM,Whitaker RS,Kondoh E,Baba T,Fujii S,Marks JR,Dressman HK,Murphy SK,Berchuck A

更新日期：2010-03-01 00:00:00

abstract：:Approximately 20,000 women are diagnosed with ovarian cancer in the United States each year, and some 12,000 women die because of it. Epithelial ovarian cancer, the most common histopathologic type, is uncommon before age 40 years, after which incidence rates increase steeply until age 70-79 years and then decrease so...

journal_title：Gynecologic oncology

authors： Whittemore AS

更新日期：1994-12-01 00:00:00

abstract：:The treatment of early vulvar carcinoma has moved toward less radical surgery with reconstruction. This report describes our preliminary experience with a mons pubis flap that is simple and appears safe, reliable, and gives excellent cosmetic and functional results following radical hemivulvectomy. Four patients have ...

journal_title：Gynecologic oncology

authors： Potkul RK,Barnes WA,Barter JF,Delgado G,Spear SL

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:To determine the incidence and risk factors for venous thromboembolism (VTE) within six months after primary debulking surgery (PDS) for epithelial ovarian cancer (EOC). METHODS:In a historical cohort, we estimated the cumulative incidence of clinically diagnosed VTE within 6 months among consecutive women w...

journal_title：Gynecologic oncology

authors： Wagner BE,Langstraat CL,McGree ME,Weaver AL,Sarangi S,Mokri B,Dowdy SC,Cliby WA,Kumar A,Bakkum-Gamez JN

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:Molecular chaperone 78 kDa glucose-regulated protein (GRP78) is a residential protein in the endoplasmic reticulum (ER) that is induced by an unfolded-protein response triggered under many kinds of stress against a cell. GRP78 is also known to act as an anti-apoptotic factor by protecting ER-stress-induced ce...

journal_title：Gynecologic oncology

authors： Luvsandagva B,Nakamura K,Kitahara Y,Aoki H,Murata T,Ikeda S,Minegishi T

更新日期：2012-07-01 00:00:00