Proteomic analysis of the function of spot in Helicobacter pylori anti-oxidative stress in vitro and colonization in vivo.

abstract：:Osteoclasts are highly differentiated terminal cells formed by fusion of hematopoietic stem cells. Previously, osteoprotegerin (OPG) inhibit osteoclast differentiation and bone resorption by blocking receptor activator of nuclear factor-κB ligand (RANKL) binding to RANK indirect mechanism. Furthermore, autophagy plays...

journal_title：Journal of cellular biochemistry

authors： Tong X,Gu J,Song R,Wang D,Sun Z,Sui C,Zhang C,Liu X,Bian J,Liu Z

更新日期：2018-09-06 00:00:00

abstract：:Conservative treatment for invasive bladder cancer (BC) involves a complete transurethral tumor resection combined with chemotherapy (CT) and radiotherapy (RT). The major obstacles of chemo-radiotherapy are the addition of the toxicities of RT and CT, and the recurrence due to RT and CT resistances. The flavonoid Sily...

journal_title：Journal of cellular biochemistry

authors： Prack Mc Cormick B,Langle Y,Belgorosky D,Vanzulli S,Balarino N,Sandes E,Eiján AM

更新日期：2018-07-01 00:00:00

abstract：:We have examined the effect of polyoma virus infection of primary mouse embryo cells on the tyrosyl kinase activity associated with the cellular src gene product, pp60c-src. The results of our studies demonstrate that infection of mouse cells with wild-type polyoma virus or viral mutants capable of transforming rodent...

journal_title：Journal of cellular biochemistry

authors： Bolen JB,Lewis AM Jr,Israel MA

更新日期：1985-01-01 00:00:00

abstract：:Cellular life-span of neonatal human brain microvascular endotheliocytes (HBME) was estimated by population doubling levels (PDLs) for serial subcultivations until spontaneous proliferation stoppage, and was 2.4-fold longer for continuous administration with the 6-O-phosphorylated derivative (TocP) of alpha-tocopherol...

journal_title：Journal of cellular biochemistry

authors： Tanaka Y,Moritoh Y,Miwa N

更新日期：2007-10-15 00:00:00

abstract：:Hepatitis C virus (HCV) is the most prevalent viral pathogen that infects more than 185 million people worldwide. HCV infection leads to chronic liver diseases such as liver cirrhosis and hepatocellular carcinoma. Direct-acting antivirals (DAAs) are the recent combination therapy for HCV infection with reduced side ef...

journal_title：Journal of cellular biochemistry

authors： Venkatesan A,Prabhu Dass J F

更新日期：2019-08-01 00:00:00

abstract：:The spatial and temporal coordination of the many events required for osteogenic cells to create a mineralized matrix are only partially understood. The complexity of this process, and the nature of the final product, demand that these cells have mechanisms to carefully monitor events in the extracellular environment ...

journal_title：Journal of cellular biochemistry

authors： Beck GR Jr

更新日期：2003-10-01 00:00:00

abstract：:All-trans-retinoic acid (ATRA) has been shown to inhibit the growth of a number of ovarian tumor cell lines while others have been found to be resistant to retinoid suppression of growth. Interestingly, two synthetic retinoids, CD437 and 4-HPR, inhibit the growth of both ATRA-sensitive (CA-OV-3) and ATRA-resistant (SK...

journal_title：Journal of cellular biochemistry

authors： Holmes WF,Soprano DR,Soprano KJ

更新日期：2003-05-15 00:00:00

abstract：:Multiple sclerosis (MS) is a highly disabling demyelinating disease, which mainly affects young adults and is difficult to cure. Activated microglia may be involved in the process of neuronal cell damage and release inflammatory cytokines to injure neurons. Rapamycin (RAPA), an immunosuppressant, can induce autophagy ...

journal_title：Journal of cellular biochemistry

authors： Xu L,Zhang C,Jiang N,He D,Bai Y,Xin Y

更新日期：2019-04-01 00:00:00

abstract：:Oral tumors are one of important tumors which could be associated with serious problems in infant and children. It has been showed that a variety of cellular and molecular pathways including genetics and epigenetics mechanisms (eg, chromosomal alterations, and microRNA) involved in pathogenesis events present in oral ...

journal_title：Journal of cellular biochemistry

authors： Khanmohammadi R,Mir F,Baniebrahimi G,Mirzaei H

更新日期：2018-03-01 00:00:00

abstract：:Lysozyme (LYZ) c-like proteins are primarily present in the testis and epididymis of male reproductive tissues. Here, we report a novel member of the c-type LYZ family, the seminal vesicle-secreted LYZ c-like protein (SVLLP). Three forms of SVLLP were purified from mouse seminal vesicle secretions and characterized as...

journal_title：Journal of cellular biochemistry

authors： Ou CM,Lee RK,Lin MH,Lu CH,Yang TH,Yeh LY,Tsai PJ,Li SH

更新日期：2021-01-19 00:00:00

abstract：:The four-subunit protease complex γ-secretase cleaves many single-pass transmembrane (TM) substrates, including Notch and β-amyloid precursor protein to generate amyloid-β (Aβ), central to Alzheimer's disease. Two of the subunits anterior pharynx-defective 1 (APH-1) and presenilin (PS) exist in two homologous forms AP...

journal_title：Journal of cellular biochemistry

authors： Dehury B,Kepp KP

更新日期：2021-01-01 00:00:00

abstract：:Undecylenic acid (UDA), a naturally occurring 11-carbon unsaturated fatty acid, has been used for several years as an economical antifungal agent and a nutritional supplement. Recently, the potential usefulness of UDA as a neuroprotective drug has been suggested based on the ability of this agent to inhibit μ-calpain ...

journal_title：Journal of cellular biochemistry

authors： Jantas D,Piotrowski M,Lason W

更新日期：2015-12-01 00:00:00

abstract：:Isoflavones widely distributed in plants prevent diabetes. This study investigated the in vivo and in vitro effect of 3',4'-dihydroxy-6″,6″,6″',6″'-tetramethylbis(pyrano[2″,3″:5,6::2″',3″':7,8]isoflavone (bis-pyrano prenyl isoflavone) on glucose homeostasis in hyperglycemic rats. The ethyl acetate fraction from aerial...

journal_title：Journal of cellular biochemistry

authors： Altenhofen D,da Luz G,Frederico MJ,Venzke D,Brich M,Vigil S,Fröde TS,Linares CE,Pizzolatti MG,Silva FR

更新日期：2017-01-01 00:00:00

abstract：:Reduced insulin receptor protein levels have been reported in the kidney cortex from diabetic humans and animals. We recently reported that, targeted deletion of insulin receptor (IR) from proximal tubules (PT) resulted in hyperglycemia in non-obese mice. To elucidate the mechanism, we examined human proximal tubule c...

journal_title：Journal of cellular biochemistry

authors： Pandey G,Shankar K,Makhija E,Gaikwad A,Ecelbarger C,Mandhani A,Srivastava A,Tiwari S

更新日期：2017-02-01 00:00:00

abstract：:A series of rapidly dividing epithelial (RDE) cell lines have been isolated from primary cultures of rat ventral prostate (RVP) epithelial cells. Unlike androgen-dependent secretory epithelial cells, the RDE cells in culture do not express the androgen-dependent secretory proteins, nor do they express the androgen-rep...

journal_title：Journal of cellular biochemistry

authors： Montpetit ML,Tenniswood MP

更新日期：1989-03-01 00:00:00

abstract：:In previous studies we have shown that all-trans retinoic acid (atRA)-treatment of the atRA-sensitive ovarian carcinoma cell line CA-OV3 repressed AP-1 activity by about 50%, while a similar effect was not observed in the atRA-resistant ovarian carcinoma cell line, SK-OV3. These results suggested that the repression o...

journal_title：Journal of cellular biochemistry

authors： Ramírez CJ,Haberbusch JM,Soprano DR,Soprano KJ

更新日期：2005-09-01 00:00:00

abstract：:For several decades, cholesterol has been thought to cause ASCVD. Limiting dietary cholesterol intake has been recommended to reduce the risk of the disease. However, several recent epidemiological studies do not support a relationship between dietary cholesterol and/or blood cholesterol and ASCVD. Consequently, the r...

journal_title：Journal of cellular biochemistry

authors： Huang SS,Liu IH,Chen CL,Chang JM,Johnson FE,Huang JS

更新日期：2017-06-01 00:00:00

abstract：:Limited information is available on the expression and role of matrix metalloproteinase (MMP)-12 in chondrocytes. We characterized the expression mechanism of MMP-12 and possible function in chondrocytes. Interleukin (IL)-1beta induced the expression and activation of MMP-12 in primary culture chondrocytes and cartila...

journal_title：Journal of cellular biochemistry

authors： Oh H,Yang S,Park M,Chun JS

更新日期：2008-12-15 00:00:00

abstract：:Fibroblast growth factor-1 (FGF1), a prototypic member of the FGF family, is a potent angiogenic factor. Although FGF-stimulated angiogenesis has been extensively studied, the molecular mechanisms regulating FGF1-induced angiogenesis are poorly understood in vivo. Fumagillin, an antiangiogenic fungal metabolite, has t...

journal_title：Journal of cellular biochemistry

authors： Chen GJ,Weylie B,Hu C,Zhu J,Forough R

更新日期：2007-08-15 00:00:00

abstract：:Male germline stem cells (mGSCs), in charge for the fertility in male testis, are the only kind of adult stem cells that transmit genetic information to next generation, with promising prospects in germplasm resources preservation and optimization, and production of transgenic animals. Mouse male germline stem cell li...

journal_title：Journal of cellular biochemistry

authors： Zhu H,Ma J,Du R,Zheng L,Wu J,Song W,Niu Z,He X,Du E,Zhao S,Hua J

更新日期：2014-09-01 00:00:00

abstract：:Macromolecules are sulfated during the vegetative growth of Dictyostelium discoideum. A characterisation of the structures of sulfated oligosaccharides associated with these macromolecules indicates that the oligosaccharides are heterogeneous. Endoglycosidase and pronase digestion were used with gel-filtration chromat...

journal_title：Journal of cellular biochemistry

authors： Davis SJ

更新日期：1988-10-01 00:00:00

abstract：:We have shown previously that the promotion of myofiber survival by the basement membrane component merosin (laminin-2 [alpha2beta1gamma1]/laminin-4 [alpha2beta2gamma1]) is dependent on the activity of the tyrosine kinase Fyn, whereas myofiber anoikis induced by merosin deficiency is dependent on the stress-activated ...

journal_title：Journal of cellular biochemistry

authors： Laprise P,Vallée K,Demers MJ,Bouchard V,Poirier EM,Vézina A,Reed JC,Rivard N,Vachon PH

更新日期：2003-08-15 00:00:00

abstract：:We have examined the composition and ultrastructure of the nuclear periphery during in vitro myogenesis of the rat myoblast cell line, L6E9. Immunofluorescence labelling and immunoblotting showed that lamins A/C and B were all present in undifferentiated cells, but that they increased significantly before extensive ce...

journal_title：Journal of cellular biochemistry

authors： Chaly N,Munro SB,Swallow MA

更新日期：1996-07-01 00:00:00

abstract：:Growth and differentiation factor 7(GDF7), also later called as bone morphogenetic protein (BMP)12, is a new member of the BMP superfamily, which induces formation of tendon-like tissue formation in the ectopic implantation experiments. We examined the effect of BMP12 on proliferation and expression of phenotype-relat...

journal_title：Journal of cellular biochemistry

authors： Furuya K,Nifuji A,Rosen V,Noda M

更新日期：1999-02-01 00:00:00

abstract：:Poor clinical outcomes of tendon repair, together with limited regenerative capacity of the tissue, have triggered the search for alternative regenerative medicine strategies. Human adipose-derived stem cells (hASCs) are being investigated as a promising cell source in contributing for tendon repopulation and reconstr...

journal_title：Journal of cellular biochemistry

authors： Costa-Almeida R,Berdecka D,Rodrigues MT,Reis RL,Gomes ME

更新日期：2018-04-01 00:00:00

abstract：:We have examined the effect of calcium-dependent adhesion, mediated by N-cadherin, on cell signaling during chondrogenesis of multipotential embryonic mouse C3H10T1/2 cells. The activity of chondrogenic genes, type II collagen, aggrecan, and Sox9 were examined in monolayer (non-chondrogenic), and micromass (chondrogen...

journal_title：Journal of cellular biochemistry

authors： Modarresi R,Lafond T,Roman-Blas JA,Danielson KG,Tuan RS,Seghatoleslami MR

更新日期：2005-05-01 00:00:00

abstract：:Prostate cancer is the second highest caused by cancer-related death among males. microRNAs (miRs) have been reported to participate in carcinogenesis, yet their roles in prostate cancer are rarely studied or investigated. Therefore, the present study attempted to explore the effect of miR-137 in prostate cancer via r...

journal_title：Journal of cellular biochemistry

authors： Wu QQ,Zheng B,Weng GB,Yang HM,Ren Y,Weng XJ,Zhang SW,Zhu WZ

更新日期：2019-06-01 00:00:00

abstract：:Colorectal cancer (CRC) brings more than 600 000 deaths every year around the globe, making itself the third most frequently occurred carcinoma. The great progress human achieved in diagnosis and treatment of various cancers has failed to reverse this trend. Fortunately, growing evidence has implied the relationship b...

journal_title：Journal of cellular biochemistry

authors： Cui G,Zhao H,Li L

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:Hepatocellular carcinoma (HCC) has a high morbidity and mortality around the world, yet the effective therapeutic option for HCC is still limited. NPAC, also known as glyoxylate reductase 1 homolog, is a new nuclear protein recently implicated in tumor biology. However, the role of NPAC in HCC remains unclear...

journal_title：Journal of cellular biochemistry

authors： Zhang J,Sun N,Guo W,Wu X,Yang X,Jin H,Zhang Y,Wu X,Zhang F,Hu L,Hu H,Gao Y

更新日期：2018-11-26 00:00:00

abstract：:We have previously shown that protein kinase Cε (PKCε) is involved in mitochondrial dysfunction in renal proximal tubular cells (RPTC). This study examined mitochondrial targets of active PKCε in RPTC injured by the model oxidant tert-butyl hydroperoxide (TBHP). TBHP exposure augmented the levels of phosphorylated (ac...

journal_title：Journal of cellular biochemistry

authors： Nowak G,Bakajsova-Takacsova D

更新日期：2018-11-01 00:00:00