Chemical components from the twigs of Caesalpinia latisiliqua and their antiviral activity.

Abstract:

:Three new compounds, (3S)-dihydrobonducellin 8-O-β-D-glucopyranoside (1), 3',5'-dimethoxy-jezonolid (2), and latisilinoid (3), along with 16 known compounds, were isolated from the twigs of Caesalpinia latisiliqua (Leguminosae). The known compounds were identified as flavonoids, stilbenes, and phenolics as determined by extensive spectroscopic methods, including 1D and 2D NMR. All the isolated compounds were evaluated for their antiviral activity in HRV1B-, CVB3-, and EV71-infected cells. Among the tested compounds, three flavonoids (4-6) and two stilbenes (12 and 14) exhibited significant antiviral activity. This is the first phytochemical investigation of C. latisiliqua twigs.

journal_name

J Nat Med

authors

Oh M,Park S,Song JH,Ko HJ,Kim SH

doi

10.1007/s11418-019-01335-2

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

26-33

issue

1

eissn

1340-3443

issn

1861-0293

pii

10.1007/s11418-019-01335-2

journal_volume

74

pub_type

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