Drosophila male-sterile mutation emmenthal specifically affects the mitochondrial morphogenesis.

Abstract:

:Proper mitochondrial morphogenesis is crucial for successful development of motile sperm. It was known that recessive Drosophila melanogaster mutation emm caused anomalies in the formation of a mitochondrial derivative--nebenkern and led to male sterility. Here we identified primary mutation effect and showed that emm is required for the formation and maintenance of inner mitochondrial structure starting from early spermatocytes. Abnormal mitochondria structure affects subsequent cellular processes in spermatogenesis such as meiotic cytokinesis and spermatid elongation.

journal_name

Protoplasma

journal_title

Protoplasma

authors

Dorogova NV,Bolobolova EU,Akhmetova KA,Fedorova SA

doi

10.1007/s00709-012-0434-2

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

515-20

issue

2

eissn

0033-183X

issn

1615-6102

journal_volume

250

pub_type

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