Abstract:
:Cryo-EM structures of Dot1L in complex with a ubiquitinated nucleosome provide the long-sought-after molecular mechanism of Dot1L-mediated methylation of lysine 79 in histone H3 and explain crosstalk with histone H2B ubiquitination.
journal_name
Mol Celljournal_title
Molecular cellauthors
Zhang Y,Kutateladze TGdoi
10.1016/j.molcel.2019.05.013subject
Has Abstractpub_date
2019-06-06 00:00:00pages
862-863issue
5eissn
1097-2765issn
1097-4164pii
S1097-2765(19)30385-5journal_volume
74pub_type
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