Hepatitis C virus quantification in serum and saliva of HCV-infected patients.

Abstract:

:The hepatitis C virus (HCV) can be detected in blood and other bodily fluids, such as saliva, semen and gastric juices. The aim of this study was to compare the HCV viral loads in the serum and saliva of infected patients. Twenty-nine patients with detectable HCV RNA in their serum and saliva were included in this study. The HCV viral loads were determined through quantitative real-time polymerase chain reactions. The median viral RNA levels were 5.78 log10 copies in the serum and 3.32 log10 copies in the saliva. We observed that the salivary HCV viral load was significantly lower than the viral load in the serum. Further studies are required to understand the role of saliva in the diagnosis, management and potential transmission of HCV.

journal_name

Mem Inst Oswaldo Cruz

authors

Menezes GB,Pereira FA,Duarte CA,Carmo TM,Silva Filho HP,Zarife MA,Krieger MA,Reis EA,Reis MG

doi

10.1590/s0074-02762012000500016

subject

Has Abstract

pub_date

2012-08-01 00:00:00

pages

680-3

issue

5

eissn

0074-0276

issn

1678-8060

pii

S0074-02762012000500016

journal_volume

107

pub_type

杂志文章
  • Gastropods as intermediate hosts of Angiostrongylus spp. in the Americas: bioecological characteristics and geographical distribution.

    abstract:BACKGROUND:Intermediate hosts are key organisms in maintaining parasite life cycles, because they can act as amplifiers in the transmission from natural reservoirs to humans. One of the most important groups of intermediate hosts for zoonotic nematode infections are gastropods,slugs and snails. These are essential orga...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章,评审

    doi:10.1590/0074-02760200236

    authors: Valente R,Robles MDR,Diaz JI

    更新日期:2020-11-27 00:00:00

  • First paleoparasitological study of an embalming rejects jar found in Saqqara, Egypt.

    abstract::For the first time, a jar of embalming rejects was studied in search for helminth parasite eggs. This kind of jar was used to put discarded material by Egyptian embalmers during mummification process. Ascaris lumbricoides and Taenia saginata eggs were found in the linen and strip fragment contents of the jar, dated of...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762003000900017

    authors: Harter S,Le Bailly M,Janot F,Bouchet F

    更新日期:2003-01-01 00:00:00

  • Monitoring the circulation of rotavirus among children after the introduction of the Rotarix™ vaccine in Goiânia, Brazil.

    abstract::The epidemiological features of rotavirus A (RVA) infection differ between children from developing and developed countries which could result in differences in vaccine efficacy around the world. To evaluate the impact of Rotarix™ on RVA prevalence, we monitored RVA genotypes circulating in Goiânia by monitoring virus...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762011000400018

    authors: Borges AM,Dias e Souza M,Fiaccadori FS,Cardoso Dd

    更新日期:2011-06-01 00:00:00

  • Experimental hepatic fibrosis due to Capillaria hepatica infection (differential features presented by rats and mice).

    abstract::Rats and mice are among the most susceptible hosts for the helminth Capillaria hepatica. More information on the similarities and differences between the hepatic pathology presented by these two parasite hosts are needed, since they may represent good models for the study of hepatic fibrosis. Early changes are similar...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762004000400010

    authors: Andrade SB,Andrade ZA

    更新日期:2004-06-01 00:00:00

  • RS virus diagnosis: comparison of isolation, immunofluorescence and enzyme immunoassay.

    abstract::Two techniques for rapid diagnosis, immunofluorescence (IFAT) and enzyme immunoassay (EIA), have been compared with virus isolation in tissue culture for the detection of respiratory syncytial virus (RSV) in specimens of nasopharyngeal secretions. The specimens were obtained from children under five years of age suffe...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02761986000200013

    authors: Siqueira MM,Ferreira V,Nascimento JP

    更新日期:1986-04-01 00:00:00

  • Actin expression in trypanosomatids (Euglenozoa: Kinetoplastea).

    abstract::Heteroxenic and monoxenic trypanosomatids were screened for the presence of actin using a mouse polyclonal antibody produced against the entire sequence of the Trypanosoma cruzi actin gene, encoding a 41.9 kDa protein. Western blot analysis showed that this antibody reacted with a polypeptide of approximately 42 kDa i...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-0276108052013015

    authors: Souza LC,Pinho RE,Lima CV,Fragoso SP,Soares MJ

    更新日期:2013-08-01 00:00:00

  • Biology of three species of North American Triatominae (Hemiptera: Reduviidae: Triatominae) fed on rabbits.

    abstract::Aspects related to hatching, lifetime, number of blood meals for molting, mortality, feeding time, and postfeeding defecation delay were evaluated and compared in each instar of three North American Triatominae: Triatoma gerstaeckeri, Triatoma lecticularia and Triatoma protracta, all of them fed on rabbits. No signifi...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762007000800006

    authors: Martínez-Ibarra JA,Alejandre-Aguilar R,Paredes-González E,Martínez-Silva MA,Solorio-Cibrián M,Nogueda-Torres B,Trujillo-Contreras F,Novelo-López M

    更新日期:2007-12-01 00:00:00

  • Using a single tablet daily to treat latent tuberculosis infection in Brazil: bioequivalence of two different isoniazid formulations (300 mg and 100 mg) demonstrated by a sensitive and rapid high-performance liquid chromatography-tandem mass spectrometry

    abstract::The recommended treatment for latent tuberculosis (TB) infection in adults is a daily dose of isoniazid (INH) 300 mg for six months. In Brazil, INH was formulated as 100 mg tablets. The treatment duration and the high pill burden compromised patient adherence to the treatment. The Brazilian National Programme for Tube...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章,随机对照试验

    doi:10.1590/0074-02760140458

    authors: Daher A,Pitta L,Santos T,Barreira D,Pinto D

    更新日期:2015-06-01 00:00:00

  • American cutaneous leishmaniasis in Pernambuco, Brazil: eco-epidemiological aspects in 'Zona da Mata' region.

    abstract::American cutaneous leishmaniasis (ACL) has been increasing in Pernambuco, thus becoming an important problem for Public Health. The incindence is predominant in the region called 'Zona da Mata', in the east of this state. This region corresponds geographically to the primitive area of the Atlantic forest. In order to ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02761994000300028

    authors: Brandão-Filho SP,de Carvalho FG,de Brito ME,Almeida Fde A,Nascimento LA

    更新日期:1994-07-01 00:00:00

  • Association between MBL2 haplotypes and dengue severity in children from Rio de Janeiro, Brazil.

    abstract:BACKGROUND:Dengue is an arthropod-borne viral disease with a majority of asymptomatic individuals and clinical manifestations varying from mild fever to severe and potentially lethal forms. An increasing number of genetic studies have outlined the association between host genetic variations and dengue severity. Genes a...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760190004

    authors: Ornelas AMM,Xavier-de-Carvalho C,Alvarado-Arnez LE,Ribeiro-Alves M,Rossi ÁD,Tanuri A,de Aguiar RS,Moraes MO,Cardoso CC

    更新日期:2019-01-01 00:00:00

  • Study of virulence factors in coagulase-negative staphylococci isolated from newborns.

    abstract::Coagulase-negative staphylococci (CNS) have been identified as the etiological agent in various infections and are currently the microorganisms most frequently isolated in nosocomial infections. However, little is known about the virulence factors produced by CNS that contribute to the pathogenesis of infections cause...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762006000600014

    authors: Cunha Mde L,Rugolo LM,Lopes CA

    更新日期:2006-09-01 00:00:00

  • Toxicological and toxicogenetic effects of plants used in popular medicine and in cattle food.

    abstract::Toxicological and toxicogenetic effects of aqueous (tea) and hexanic fruit extract of Indigofera suffruticosa Mill. and hydroalcoholic root extract of Solanum agrarium Stendt. were evaluated in Balb C male mice intraperitoneally exposed. A hepatotoxic effect was observed just for animals treated with aqueous fruit ext...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02761991000600022

    authors: Ribeiro LR,Bautista AR,Silva AR,Sales LA,Salvadori DM,Maia PC

    更新日期:1991-01-01 00:00:00

  • Description of Warileya lumbrerasi n. sp. (Diptera:Psychodidae) from Peru.

    abstract::Warileya lumbrerasi n. sp. is described from the northern Peruvian Andes. This species was collected inside houses, and is the seventh species described within the genus Warileya Hertig, 1948. ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02761996000600010

    authors: Ogusuku E,Perez JE,Davies CR,Villaseca P

    更新日期:1996-11-01 00:00:00

  • Functional complementation of a yeast knockout strain by Schistosoma mansoni Rho1 GTPase in the presence of caffeine, an agent that affects mutants defective in the protein kinase C signal transduction pathway.

    abstract::In a previous study, the Schistosoma mansoni Rho1 protein was able to complement Rho1 null mutant Saccharomyces cerevisiae cells at restrictive temperatures and under osmotic stress (low calcium concentration) better than the human homologue (RhoA). It is known that under osmotic stress, the S. cerevisiae Rho1 trigger...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762006000900051

    authors: Aguiar PH,Santos DN,Lobo FP,Santos TM,Macedo AM,Pena SD,Machado CR,Franco GR

    更新日期:2006-09-01 00:00:00

  • Schistosome vaccine testing: lessons from the baboon model.

    abstract::The high level of protection elicited in rodents and primates by the radiation-attenuated schistosome vaccine gives hope that a human vaccine relying on equivalent mechanisms is feasible. In humans, a vaccine would be undoubtedly administered to previously or currently infected individuals. We have therefore used the ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762006000900061

    authors: Coulson PS,Kariuki TM

    更新日期:2006-09-01 00:00:00

  • Purification and biochemical characterization of four iron superoxide dismutases in Trypanosoma cruzi.

    abstract::Four superoxide dismutase (SOD) activities (SOD I, II, III, and IV) have been characterized in the epimastigote form of Trypanosoma cruzi. The total extract was subjected to two successive ammonium sulphate additions between 35 and 85%, and the resulting fraction was purified using two continuous chromatography proces...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762008000300008

    authors: Mateo H,Marín C,Pérez-Cordón G,Sánchez-Moreno M

    更新日期:2008-05-01 00:00:00

  • Association of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazil.

    abstract::The seroprevalence of toxoplasmosis in 832 pregnant women in Miracema, Rio de Janeiro, was determined and 75.1% (625) and 2.0% (17) were anti-Toxoplasma gondii IgG and IgM positive, respectively. Out of the 17 IgM positive pregnant women, only one had low avidity IgG corresponding to the acute phase of the infection. ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762008000600013

    authors: Ribeiro AC,Mutis MS,Fernandes O

    更新日期:2008-09-01 00:00:00

  • Acanthocefalan eggs in animal coprolites from archaeological sites from Brazil.

    abstract::An important point in paleoparasitology is the correct diagnosis of the origin of coprolites found in archaeological sites. The identification of human and animal coprolites, through the study of the shape, size, characteristics after rehydration, alimentary contents, and the presence of parasites, has proved to be ac...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02761989000200007

    authors: Ferreira LF,Araújo A,Confalonieri U,Chame M

    更新日期:1989-04-01 00:00:00

  • The first record of Lutzomyia longipalpis in the Argentine northwest.

    abstract::In 2004, the urban presence of Lutzomyia longipalpis was recorded for the first time in Formosa province. In 2006, the first autochthonous case of human urban visceral leishmaniasis (VL) was recorded in Misiones in the presence of the vector, along with some canine VL cases. After this first case, the vector began to ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-0276130358

    authors: Bravo AG,Quintana MG,Abril M,Salomón OD

    更新日期:2013-12-01 00:00:00

  • Distribution and Schistosoma mansoni infection of Biomphalaria glabrata in different habitats in a rural area in the Jequitinhonha Valley, Minas Gerais, Brazil: environmental and epidemiological aspects.

    abstract::This paper examines the distribution and infection of Biomphalaria glabrata with Schistosoma mansoni in all aquatic snail habitats in a rural area in the state of Minas Gerais, Brazil, in relation to physico/biotic and behavioral factors. Snail and environmental surveys were carried out semi-annually between July 2001...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762004000700002

    authors: Kloos H,Passos LK,Loverde P,Oliveira RC,Gazzinelli A

    更新日期:2004-11-01 00:00:00

  • Lutzomyia diamantinensis sp. nov., a new phlebotomine species (Diptera: Psychodidae) from a quartzite cave in Diamantina, state of Minas Gerais, Brazil.

    abstract::A new species of Brazilian phlebotomine sandfly found in Brazil, municipality of Diamantina, state of Minas Gerais, is described based on males and females collected in a quartzite cave. The body of spermathecae is continuous to the individual duct, lanky and tapering at the end, with conical shaped, not striated and ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762012000800007

    authors: Barata RA,Serra e Meira PC,Carvalho GM

    更新日期:2012-12-01 00:00:00

  • Increasing the digital repository of DNA barcoding sequences of sand flies (Psychodidae: Phlebotominae).

    abstract::Sand fly identification is complex because it depends on the expertise of the taxonomist. The females show subtle morphological differences and the occurrence of the species complexes are usual in this taxon. Therefore, a fragment of the cytochrome c oxidase subunit I (COI) gene is used for taxon barcoding to resolve ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760190208

    authors: Laurito M,Ontivero IM,Almirón WR

    更新日期:2019-11-28 00:00:00

  • Borrelia-like spirochetes recovered from ticks and small mammals collected in the Atlantic Forest Reserve, Cotia county, State of São Paulo, Brazil.

    abstract::Forty-four marsupials, 77 rodents and 161 ticks were captured in an Atlantic Forest Reserve in Cotia county, State of São Paulo, where human cases of Lyme disease (LD) simile were reported. Twenty-one borrelia-like spirochete isolates were recovered from the mammals' blood and rodent livers or spleens, and triturated ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762000000500006

    authors: Abel IS,Marzagão G,Yoshinari NH,Schumaker TT

    更新日期:2000-09-01 00:00:00

  • The infection of microvascular endothelial cells with ExoU-producing Pseudomonas aeruginosa triggers the release of von Willebrand factor and platelet adhesion.

    abstract::An increased plasma concentration of von Willebrand factor (vWF) is detected in individuals with many infectious diseases and is accepted as a marker of endothelium activation and prothrombotic condition. To determine whether ExoU, a Pseudomonas aeruginosa cytotoxin with proinflammatory activity, enhances the release ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762012000600004

    authors: Freitas C,Assis MC,Saliba AM,Morandi VM,Figueiredo CC,Pereira M,Plotkowski MC

    更新日期:2012-09-01 00:00:00

  • Evolutionary study of potentially zoonotic hepatitis E virus genotype 3 from swine in Northeast Brazil.

    abstract::Hepatitis E virus (HEV), an emerging virus associated with acute hepatic disease, leads to thousands of deaths worldwide. HEV has already been reported in Brazil; however, there is a lack of epidemiological and molecular information on the genetic variability, taxonomy, and evolution of HEV. It is thus unclear whether...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760180585

    authors: Oliveira-Filho EF,Dos Santos DR,Durães-Carvalho R,da Silva A,de Lima GB,Batista Filho AFB,Pena LJ,Gil LH

    更新日期:2019-01-01 00:00:00

  • The type specimens of chewing lice (Insecta, Mallophaga) deposited in the entomological collection of Instituto Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.

    abstract::This paper presents a list of 131 Mallophaga type specimens deposited in the Werneck Collection of Instituto Oswaldo Cruz, Rio de Janeiro, RJ, Brazil. It includes 69 holotypes, 62 allotypes, 683 paratypes, 1 syntype and 2 neoparatypes, distributed among 6 families and 35 genera. The types are listed with their respect...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762003000200012

    authors: Cardozo-de-Almeida M,Linardi PM,Costa J

    更新日期:2003-03-01 00:00:00

  • Sylvatic population of Triatoma infestans from the Bolivian Chaco: from field collection to characterization.

    abstract::A sylvatic Triatoma infestans DM (dark morph) population detected in the Bolivian Chaco was characterized and compared with various domestic ones. The degree of differentiation of DM was clearly within the T. infestans intra-specific level. Nevertheless marked chromatic and morphometric differences as well as differen...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762000000700020

    authors: Noireau F,Bastrenta B,Catalá S,Dujardin JP,Panzera F,Torres M,Perez R,Galvão C,Jurberg J

    更新日期:2000-01-01 00:00:00

  • Remodeling of hepatic vascular changes after specific chemotherapy of schistosomal periportal fibrosis.

    abstract::Hepatosplenic schistosomiasis was the first human disease in which the possibility of extensive long standing hepatic fibrosis being degraded and removed has been demonstrated. When such changes occurred, the main signs of portal hypertension (splenomegaly, esophageal varices) progressively disappeared, implying that ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762006000900041

    authors: Andrade ZA,Baptista AP,Santana TS

    更新日期:2006-09-01 00:00:00

  • Biology of the first generation of a laboratory colony of Nyssomyia intermedia (Lutz & Neiva, 1912) and Nyssomyia neivai (Pinto, 1926) (Diptera: Psychodidae).

    abstract::The phlebotomine sand flies Nyssomyia intermedia (Lutz & Neiva, 1912) and Nyssomyia neivai (Pinto, 1926) are very close and may be involved in the transmission of Leishmania spp. Ross, 1903 in Brazil. The biology of the first laboratory-reared generations of these species, descended from insects captured in Além Paraí...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762004000600011

    authors: Andrade Filho JD,Galati EA,Falcão AL

    更新日期:2004-10-01 00:00:00

  • Effect of angiotensin II and losartan on the phagocytic activity of peritoneal macrophages from Balb/C mice.

    abstract::Angiotensin II (AII), a product of rennin-angiotensin system, exerts an important role on the function of immune system cells. In this study, the effect of AII on the phagocytic activity of mouse peritoneal macrophages was assessed. Mice peritoneal macrophages were cultured for 48 h and the influence of different conc...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/s0074-02762004000200009

    authors: Belline P,da Melo PS,Haun M,Palhares FB,Boer PA,Gontijo JA,Figueiredo JF

    更新日期:2004-03-01 00:00:00