Abstract:
:We report the complete genome sequence of Pseudomonas aeruginosa siphophage MP1412, which displays synteny to those of P. aeruginosa phages M6 and YuA. However, the presence of two homing endonucleases of the GIY-YIG family is unique to MP1412, suggesting their unique role in the phage life cycle of the bacterial host.
journal_name
J Viroljournal_title
Journal of virologyauthors
Bae HW,Chung IY,Sim N,Cho YHdoi
10.1128/JVI.01403-12subject
Has Abstractpub_date
2012-09-01 00:00:00pages
9537issue
17eissn
0022-538Xissn
1098-5514pii
86/17/9537journal_volume
86pub_type
杂志文章abstract::The major DNA-binding protein encoded by several temperature-sensitive mutants of herpes simplex virus type 1 was thermolabile for binding to intracellular viral DNA. The ability of DNase I to release this protein from isolated nuclei was used as a measure of the amount of protein bound to viral DNA. This assay was ba...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.46.3.909-919.1983
更新日期:1983-06-01 00:00:00
abstract::The vaccinia virus Western Reserve A38L protein is a hydrophobic integral membrane glycoprotein with amino acid similarity to mammalian integrin-associated protein. The protein has an N-terminal immunoglobulin superfamily domain, followed by five membrane-spanning domains and a short cytoplasmic tail. Deletion of the ...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.70.2.905-914.1996
更新日期:1996-02-01 00:00:00
abstract::The 2009 pandemic influenza virus (pdm/09) has been frequently introduced to pigs and has reassorted with other swine viruses. Recently, H3N2 reassortants with pdm/09-like internal genes were isolated in Guangxi and Hong Kong, China. Genetic and epidemiological analyses suggest that these viruses have circulated in sw...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.06824-11
更新日期:2012-02-01 00:00:00
abstract:UNLABELLED:Bluetongue is one of the major infectious diseases of ruminants and is caused by bluetongue virus (BTV), an arbovirus existing in nature in at least 26 distinct serotypes. Here, we describe the development of a vaccine platform for BTV. The advent of synthetic biology approaches and the development of revers...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.02183-14
更新日期:2014-11-01 00:00:00
abstract::Mouse-adapted dengue type 4 virus (DEN4) strain H241 is highly neurovirulent for mice, whereas its non-mouse-adapted parent is rarely neurovirulent. The genetic basis for the neurovirulence of the mouse-adapted mutant was studied by comparing intratypic chimeric viruses that contained the three structural protein gene...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.67.11.6567-6575.1993
更新日期:1993-11-01 00:00:00
abstract::A procedure has been developed for the isolation of Newcastle disease virus (NDV) envelope proteins. The two surface glycoproteins and the non-glycosylated membrane protein were solubilized with 2% Triton X-100 and 1 m KCl. Removal of the KCl by dialysis yielded by precipitation a pure preparation of the non-glycosyla...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.11.2.263-271.1973
更新日期:1973-02-01 00:00:00
abstract::We have investigated the ability of human immunodeficiency virus type 1 (HIV-1) and HIV-2 isolates to infect and replicate in primary human macrophages. Monocytes from blood donors were allowed to differentiate into macrophages by culture in the presence of autologous lymphocytes and human serum for 5 days before infe...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.68.10.6684-6689.1994
更新日期:1994-10-01 00:00:00
abstract::We investigated the synergism between influenza virus and Streptococcus pneumoniae, particularly the role of deletions in the stalk region of the neuraminidase (NA) of H2N2 and H9N2 avian influenza viruses. Deletions in the NA stalk (ΔNA) had no effect on NA activity or on the adherence of S. pneumoniae to virus-infec...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.05809-11
更新日期:2012-04-01 00:00:00
abstract::We have studied protein synthesis in cultured cells infected with the six noncytopathic (nc) mutants of the Australia-Victoria strain (AV-WT) of Newcastle disease virus and their plaque-forming revertants. Virus-specific polypeptides accumulated at 30 to 63% of wild-type levels in nc mutant-infected cells and between ...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.40.3.691-702.1981
更新日期:1981-12-01 00:00:00
abstract::While the facile transmission of chronic wasting disease (CWD) remains incompletely elucidated, studies in rodents suggest that exposure of the respiratory mucosa may be an efficient pathway. The present study was designed to address this question in the native cervid host. Here, we demonstrate aerosol transmission of...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.02852-12
更新日期:2013-02-01 00:00:00
abstract::The required activities of CD4(+) T cells and antibody against the virally encoded oncoprotein simian virus 40 (SV40) Tag have previously been demonstrated by our laboratory to be mediators in achieving antitumor responses and tumor protection through antibody-dependent cell-mediated cytotoxicity (ADCC). In this study...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.01512-09
更新日期:2010-01-01 00:00:00
abstract::The herpes simplex virus (HSV) heterodimer gE/gI and another membrane protein, US9, which has neuron-specific effects, promote the anterograde transport of virus particles in neuronal axons. Deletion of both HSV gE and US9 blocks the assembly of enveloped particles in the neuronal cytoplasm, which explains why HSV vir...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.01113-20
更新日期:2020-11-09 00:00:00
abstract::Several lines of evidence suggest that various cofactors may be required for prion replication. PrP binds to polyanions, and RNAs were shown to promote the conversion of PrP(C) into PrP(Sc) in vitro. In the present study, we investigated strain-specific differences in RNA requirement during in vitro conversion and the...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.01286-12
更新日期:2012-10-01 00:00:00
abstract::Guinea pig antisera and mouse monoclonal antibodies against a 40,000-molecular-weight nucleocapsid protein (p40) of herpes simplex virus types 1 and 2 immunoprecipitated 40,000- and 80,000-molecular-weight classes of soluble proteins from infected cell extracts. The soluble 40,000-molecular-weight protein class (intra...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.35.3.644-652.1980
更新日期:1980-09-01 00:00:00
abstract::Phosphorylation of the βC1 protein encoded by the betasatellite of tomato yellow leaf curl China virus (TYLCCNB-βC1) by SNF1-related protein kinase 1 (SnRK1) plays a critical role in defense of host plants against geminivirus infection in Nicotiana benthamiana However, how phosphorylation of TYLCCNB-βC1 impacts its pa...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.00300-17
更新日期:2017-07-27 00:00:00
abstract::Rift Valley fever (RVF) virus (RVFV) can cause severe human disease characterized by either acute-onset hepatitis, delayed-onset encephalitis, retinitis and blindness, or a hemorrhagic syndrome. The existing nonhuman primate (NHP) model for RVF utilizes an intravenous (i.v.) exposure route in rhesus macaques (Macaca m...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.06190-11
更新日期:2012-02-01 00:00:00
abstract::Adenovirus types 5 and 3 (Ad5 and Ad3), two human adenovirus serotypes of evolutionarily divergent subgroups, show very different levels of E1A gene expression early after infection of permissive cells. Since adenovirus E1A gene expression is known to be transcriptionally autoregulated, we have investigated the differ...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.63.4.1833-1838.1989
更新日期:1989-04-01 00:00:00
abstract::The internal hydrophobic sequence within the flaviviral capsid protein (protein C) plays an important role in the assembly of infectious virions. Here, this sequence was analyzed in a West Nile virus lineage I isolate (crow V76/1). An infectious cDNA clone was constructed and used to introduce deletions into the inter...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.02653-08
更新日期:2009-06-01 00:00:00
abstract::Developing an immunotherapy to keep human immunodeficiency virus type 1 (HIV-1) replication suppressed while discontinuing highly active antiretroviral therapy (HAART) is an important challenge. In the present work, we evaluated in vitro whether dendritic cells (DC) electroporated with gag mRNA can induce HIV-specific...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.02080-07
更新日期:2008-04-01 00:00:00
abstract::Adenoviral RNA sequences synthesized in nuclei isolated during the late phase of productive infection comprise, besides virus-associated, VA, RNA, five major species, ranging in size from approximately 13S to 55S. The latter RNA species is of the length predicted if the major transcriptional unit expressed during the ...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.32.2.394-403.1979
更新日期:1979-11-01 00:00:00
abstract::Hepatitis C virus (HCV) replication in infected patients produces large and diverse viral populations, which give rise to drug-resistant and immune escape variants. Here, we analyzed HCV populations during transmission and diversification in longitudinal and cross-sectional samples using 454/Roche pyrosequencing, in t...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.02271-09
更新日期:2010-06-01 00:00:00
abstract::Adenovirus type 12 (Huie) inoculated into cultures of primary whole rat embryo produced foci of morphologically altered cells. The number and identification of these transformed areas was dependent upon the calcium concentration of the medium; more foci appeared in 0.1 mm than in 1.8 mm calcium. Cell lines derived fro...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.1.2.362-367.1967
更新日期:1967-04-01 00:00:00
abstract::Herpes simplex virus 1 (HSV-1) establishes lifelong latent infections in neurons. Reactivation from latency can lead to serious recurrent disease, including stromal keratitis, corneal scarring, blindness, and encephalitis. Although numerous studies link stress to an increase in the incidence of reactivation from laten...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.00418-19
更新日期:2019-06-14 00:00:00
abstract::Streptomyces coelicolor is a model system for the study of Streptomyces, a genus of bacteria responsible for the production of many clinically important antibiotics. Here we report the genome sequence of ΦCAM, a new S. coelicolor generalized transducing bacteriophage, isolated from a soil sample originating from Linco...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.02681-12
更新日期:2012-12-01 00:00:00
abstract::The two canine adenoviruses, infectious canine hepatitis (ICH) virus and infectious canine laryngotracheitis (ICL) virus (also designated as Toronto A26/61 virus), were studied with respect to their morphology and the biological properties of their soluble components. The two viruses were found to be composed of solub...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.5.4.507-512.1970
更新日期:1970-04-01 00:00:00
abstract::The large-particle fraction from the cytoplasm of chick embryo fibroblasts infected with Semliki Forest virus was found to catalyze the incorporation of the 5'-triphosphates of guanosine, adenine, cytidine, and uridine into an acid-insoluble alkali-labile product. The conditions affecting the preparation and assay of ...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.1.1.97-109.1967
更新日期:1967-02-01 00:00:00
abstract::In search of an anti-transcriptase, antibody was raised in rabbits to partially purified, soluble NS protein present in cytoplasmic extracts of cells infected with the Indiana serotype of vesicular stomatitis (VSInd) virus. This antiserum gave specific reactions of identity by agar immunodiffusion with both cytoplasmi...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.15.6.1357-1366.1975
更新日期:1975-06-01 00:00:00
abstract::Axl, a plasma membrane-associated Tyro3/Axl/Mer (TAM) family member, is necessary for optimal Zaire ebolavirus (ZEBOV) glycoprotein (GP)-dependent entry into some permissive cells but not others. To date, the role of Axl in virion entry is unknown. The focus of this study was to characterize entry pathways that are us...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.01278-09
更新日期:2011-01-01 00:00:00
abstract::Tetherin/BST-2 is a host-encoded protein that restricts a wide diversity of viruses at the stage of virion release. However, viruses have evolved antagonists of Tetherin, including the Vpu and Nef proteins of primate lentiviruses. Like other host genes subject to viral antagonism, primate Tetherin genes have evolved u...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.00468-10
更新日期:2010-07-01 00:00:00
abstract::The envelope glycoprotein (GP) of lymphocytic choriomeningitis virus (LCMV) is posttranslationally cleaved into two subunits. We show here that this endoproteolytic processing is not required for transport to the cell surface but is essential for LCMV GP to mediate infectivity of pseudotyped retroviral vectors. By sys...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/jvi.77.5.2866-2872.2003
更新日期:2003-03-01 00:00:00