Ciliary signaling cascades in photoreceptors.

Abstract:

:For being a polarized neuron and having a sensory cilium, photoreceptors attract remarkable attention. This is due their highly polarized structure and active visual signal transduction cascades and for the enrichment of complex networks of proteins in the cilium. Structural and functional maintenance of the photoreceptor sensory cilium, also called outer segment, ensures that light signal is received and relayed appropriately to the brain. Any perturbations in the protein content of the outer segment result in photoreceptor dysfunction, degeneration and eventually, blindness. This review focuses on the importance of photoreceptor sensory cilium to carry out signal transduction cascade for vision.

journal_name

Vision Res

journal_title

Vision research

authors

Yildiz O,Khanna H

doi

10.1016/j.visres.2012.08.007

subject

Has Abstract

pub_date

2012-12-15 00:00:00

pages

112-6

eissn

0042-6989

issn

1878-5646

pii

S0042-6989(12)00257-X

journal_volume

75

pub_type

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