Abstract:
:For being a polarized neuron and having a sensory cilium, photoreceptors attract remarkable attention. This is due their highly polarized structure and active visual signal transduction cascades and for the enrichment of complex networks of proteins in the cilium. Structural and functional maintenance of the photoreceptor sensory cilium, also called outer segment, ensures that light signal is received and relayed appropriately to the brain. Any perturbations in the protein content of the outer segment result in photoreceptor dysfunction, degeneration and eventually, blindness. This review focuses on the importance of photoreceptor sensory cilium to carry out signal transduction cascade for vision.
journal_name
Vision Resjournal_title
Vision researchauthors
Yildiz O,Khanna Hdoi
10.1016/j.visres.2012.08.007subject
Has Abstractpub_date
2012-12-15 00:00:00pages
112-6eissn
0042-6989issn
1878-5646pii
S0042-6989(12)00257-Xjournal_volume
75pub_type
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