Differential predictive value of depressive versus anxiety symptoms in the prediction of 8-year mortality after acute coronary syndrome.

Abstract:

OBJECTIVE:Both depression and anxiety have been associated with poor prognosis in patients with acute coronary syndrome (ACS). However, certain symptoms and how they are measured may be more important than others. We investigated three different scales to determine their predictive validity. METHODS:Patients with ACS (N = 598) completed either the Hospital Anxiety and Depression Scales (HADS-A, HADS-D; n = 316) or the Beck Depression Inventory-Fast Screen (n = 282). Their all-cause mortality status was assessed at 8 years. RESULTS:During follow-up, 20% (121/598) of participants died. Cox proportional hazards modeling showed that the HADS-D was predictive of mortality (hazard ratio [HR] = 1.11, 95% confidence interval [CI] = 1.04-1.19), and this association remained significant after adjustment for major clinical/demographic factors, whereas the HADS-A (HR = 0.96, 95% CI = 0.85-1.09) and the Beck Depression Inventory-Fast Screen (HR = 0.99, 95% CI = 0.91-1.08) were not. The following depression items from the HADS-D predicted mortality: "I still enjoy the things I used to enjoy" (HR = 1.38, 95% CI = 1.05-1.82), "I can laugh and see the funny side of things" (HR = 1.48, 95% CI = 1.11-1.96), "I feel as if I am slowed down" (HR = 1.66, 95% CI = 1.24-2.22), and "I look forward with enjoyment to things" (HR = 1.36, 95% CI = 1.08-1.72). CONCLUSIONS:Depressive symptoms related to lack of enjoyment or pleasure and physical or cognitive slowing, as measured by the HADS-D, predicted all-cause mortality at 8 years ACS patients, whereas other depressive and anxiety symptoms did not. Whether symptoms of distress predict prognosis in ACS seems to be dependent on the measures and items used.

journal_name

Psychosom Med

journal_title

Psychosomatic medicine

authors

Doyle F,Conroy R,McGee H

doi

10.1097/PSY.0b013e318268978e

subject

Has Abstract

pub_date

2012-09-01 00:00:00

pages

711-6

issue

7

eissn

0033-3174

issn

1534-7796

pii

PSY.0b013e318268978e

journal_volume

74

pub_type

杂志文章
  • A follow-up study of thirty hospitalized bulimics.

    abstract::Thirty normal-weight female bulimics were followed up 2-5 years following hospital admission using semistructured interviews and psychometric measures. Inasmuch as bulimia was only recently designated a distinct disorder, questions have emerged with regard to its clinical course and diagnostic validity. Results of thi...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198701000-00004

    authors: Swift WJ,Ritholz M,Kalin NH,Kaslow N

    更新日期:1987-01-01 00:00:00

  • Social interactions, communications, and the coronary-prone behavior pattern: a psychophysiological study.

    abstract::Sixty subjects classified as either Type A or Type B interacted in pairs by pressing buttons which transmitted messages through a television screen while the heart rate and digital blood volume pulse were computer-monitored. Partners could cooperate, compete, punish, reward, or withdraw on each interaction and could s...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197902000-00002

    authors: Van Egeren LF

    更新日期:1979-02-01 00:00:00

  • Sexual orientation and disclosure in relation to psychiatric symptoms, diurnal cortisol, and allostatic load.

    abstract:OBJECTIVES:Lesbian, gay, and bisexual (LGB) individuals-particularly those who have not disclosed their sexual orientation-are believed to experience increased chronic stress in comparison with heterosexuals. This interdisciplinary study assessed whether psychiatric symptoms (self-rated anxiety, depression, and burnout...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3182826881

    authors: Juster RP,Smith NG,Ouellet É,Sindi S,Lupien SJ

    更新日期:2013-02-01 00:00:00

  • Neural correlates of levels of emotional awareness during trauma script-imagery in posttraumatic stress disorder.

    abstract:OBJECTIVE:To examine individual differences in levels of emotional awareness as a predictor of the blood oxygenation level dependent (BOLD) response to trauma script-driven imagery in trauma-exposed individuals with (n = 25) and without (n = 16) posttraumatic stress disorder (PTSD). METHODS:Participants completed the ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31815f66d4

    authors: Frewen P,Lane RD,Neufeld RW,Densmore M,Stevens T,Lanius R

    更新日期:2008-01-01 00:00:00

  • Increased risks of acute organ dysfunction and mortality in intensive care unit patients with schizophrenia: a nationwide population-based study.

    abstract:OBJECTIVE:To investigate the risks of acute organ dysfunction and death in intensive care unit (ICU) patients with schizophrenia. METHODS:Using a retrospective matched cohort design, we compared 203 schizophrenic patients to 2036 demographically matched (1:10) nonschizophrenic patients with first-time ICU admission be...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3182280016

    authors: Shen HN,Lu CL,Yang HH

    更新日期:2011-09-01 00:00:00

  • Negative affectivity and repressive coping: pervasive influence on self-reported mood, health, and coronary-prone behavior.

    abstract::Negative affectivity (NA) and repressive coping (REP) are coping styles characterized by a disposition to either experience or avoid distress. This study investigated the potential influence of NA and REP on self-reported distress and coronary-prone behavior among 178 male cardiac patients undergoing rehabilitation. B...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199109000-00005

    authors: Denollet J

    更新日期:1991-09-01 00:00:00

  • Patterning of cognitive and somatic processes in the self-regulation of anxiety: effects of meditation versus exercise.

    abstract::Davidson and Schwartz (1) have proposed a psychobiological analysis of anxiety that emphasizes the patterning of multiple processes in the generation and self-regulation of this state. The present article specifically reviews recent research on cognitive and somatic components of anxiety. A dual component scale which ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197806000-00004

    authors: Schwartz GE,Davidson RJ,Goleman DJ

    更新日期:1978-06-01 00:00:00

  • Role of depression, stress, and trauma in HIV disease progression.

    abstract::Despite advances in HIV treatment, there continues to be great variability in the progression of this disease. This paper reviews the evidence that depression, stressful life events, and trauma account for some of the variation in HIV disease course. Longitudinal studies both before and after the advent of highly acti...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/PSY.0b013e3181777a5f

    authors: Leserman J

    更新日期:2008-06-01 00:00:00

  • Life events and myocardial infarction revisited: the role of measures of individual impact.

    abstract::This study was conducted to test the hypothesis that patients with MI are distinguished from persons with a less serious illness, more by subjective interpretations of the emotional impact of life events than by exposure to a surfeit of life events that purportedly representative samples of the population have judged ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198001000-00001

    authors: Byrne DG,Whyte HM

    更新日期:1980-01-01 00:00:00

  • Stressful events, pessimism, natural killer cell cytotoxicity, and cytotoxic/suppressor T cells in HIV+ black women at risk for cervical cancer.

    abstract:OBJECTIVE:This study examines whether stressful negative life events and pessimism were associated with lower natural killer cell cytotoxicity (NKCC) and T cytotoxic/suppressor cell (CD8+CD3+) percentage in black women co-infected with human immunodeficiency virus Type 1 (HIV-1) and human papillomavirus (HPV), a viral ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199811000-00009

    authors: Byrnes DM,Antoni MH,Goodkin K,Efantis-Potter J,Asthana D,Simon T,Munajj J,Ironson G,Fletcher MA

    更新日期:1998-11-01 00:00:00

  • The relation between dominance, anger, and hormones in normally aging men: results from the Massachusetts Male Aging Study.

    abstract::This paper examines the relation of two personality characteristics (dominance and anger) to hormones in normally aging men. The relation of the Jackson Personality Research Form E Dominance subscale and the Spielberger Anger Expression scale to serum levels of 17 endocrine variables, including testosterone (T) and di...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199107000-00003

    authors: Gray A,Jackson DN,McKinlay JB

    更新日期:1991-07-01 00:00:00

  • Modeling social influences on human health.

    abstract::Social interactions have long-term physiological, psychological, and behavioral consequences. Social isolation is a well-recognized but little understood risk factor and prognostic marker of disease; it can have profoundly detrimental effects on both mental and physical well-being, particularly during states of compro...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/PSY.0b013e3182002116

    authors: Karelina K,DeVries AC

    更新日期:2011-01-01 00:00:00

  • Higher abnormal leukocyte and lymphocyte counts 20 years after exposure to severe stress: research and clinical implications.

    abstract:OBJECTIVES:Research suggests that individuals with posttraumatic stress disorder (PTSD) are more likely to develop medical conditions and other stress-related psychiatric disorders. Given these findings and others suggesting that PTSD victims may have altered neuroendocrine and immune systems, the hypothesis that Vietn...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006842-199905000-00019

    authors: Boscarino JA,Chang J

    更新日期:1999-05-01 00:00:00

  • Indirect effects of elevated body mass index on memory performance through altered cerebral metabolite concentrations.

    abstract:OBJECTIVE:Elevated body mass index (BMI) at midlife is associated with increased risk of cognitive decline in later life. The goal of the current study was to assess mechanisms of early brain vulnerability by examining if higher BMI at midlife affects current cognitive performance through alterations in cerebral neuroc...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31825ff1de

    authors: Gonzales MM,Tarumi T,Eagan DE,Tanaka H,Vaghasia M,Haley AP

    更新日期:2012-09-01 00:00:00

  • Self-efficacy and health status in patients with coronary heart disease: findings from the heart and soul study.

    abstract:OBJECTIVE:To examine the relationship between cardiac self-efficacy and health status, including symptom burden, physical limitation, quality of life, and overall health among outpatients with stable coronary heart disease (CHD). We hypothesized that lower self-efficacy would predict worse health status, independent of...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3180514d57

    authors: Sarkar U,Ali S,Whooley MA

    更新日期:2007-05-01 00:00:00

  • Behavioral and physiological effects of a beta blocker and relaxation therapy on mild hypertensives.

    abstract::In this industrial-based study we compared the blood pressure (BP)-lowering effectiveness of relaxation, a beta blocker, and the combined use of these two treatments in 47 untreated, mildly hypertensive blue collar steel workers. Using a randomized two by two factorial design, patients received either nadolol or place...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-198909000-00004

    authors: Adsett CA,Bellissimo A,Mitchell A,Wilczynski N,Haynes RB

    更新日期:1989-09-01 00:00:00

  • Cardiovascular-emotional dampening: the relationship between blood pressure and recognition of emotion.

    abstract:OBJECTIVE:Persons with elevated blood pressure (BP) show dampened emotional responses to affect-laden stimuli. We sought to further examine cardiovascular-emotional dampening by examination of the relationship between resting hemodynamic measures and recognition of emotion in an African American community-based sample....

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e318235ed55

    authors: McCubbin JA,Merritt MM,Sollers JJ 3rd,Evans MK,Zonderman AB,Lane RD,Thayer JF

    更新日期:2011-11-01 00:00:00

  • Chronic interpersonal stress predicts activation of pro- and anti-inflammatory signaling pathways 6 months later.

    abstract:OBJECTIVE:To understand the mechanisms underlying chronic interpersonal difficulties and their detrimental influence on mental and physical health. METHODS:A total of 103 healthy young women (mean age = 17 years) were administered a structured interview to assess the degree of chronic interpersonal stress in their liv...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e318190d7de

    authors: Miller GE,Rohleder N,Cole SW

    更新日期:2009-01-01 00:00:00

  • Hypothalamic-pituitary-adrenocortical responses to psychological stress and caffeine in men at high and low risk for hypertension.

    abstract:OBJECTIVE:This study examined pituitary-adrenocortical responses to dietary doses of caffeine (3.3 mg/kg, equivalent to 2 to 3 cups of coffee), alone and combined with behavioral stress, in men at high risk versus low risk for hypertension. A randomized, double-blind, caffeine-placebo crossover design was used. METHOD...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199807000-00021

    authors: al'Absi M,Lovallo WR,McKey B,Sung BH,Whitsett TL,Wilson MF

    更新日期:1998-07-01 00:00:00

  • Neural correlates of giving support to a loved one.

    abstract:OBJECTIVE:Social support may benefit mental and physical well-being, but most research has focused on the receipt, rather than the provision, of social support. We explored the potentially beneficial effects of support giving by examining the neural substrates of giving support to a loved one. We focused on a priori re...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3182359335

    authors: Inagaki TK,Eisenberger NI

    更新日期:2012-01-01 00:00:00

  • Blood pressure reactions to acute mental stress and future blood pressure status: data from the 12-year follow-up of the West of Scotland Study.

    abstract:OBJECTIVE:To test the reactivity hypothesis using blood pressure data collected 12 years after baseline. This study examined whether blood pressure reactions to acute mental stress predicted future blood pressure resting levels, as well as the temporal drift in resting blood pressure, and whether the prediction was aff...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3182359808

    authors: Carroll D,Phillips AC,Der G,Hunt K,Benzeval M

    更新日期:2011-11-01 00:00:00

  • Effects of total sleep deprivation in major depression: overnight improvement of mood is accompanied by increased pain sensitivity and augmented pain complaints.

    abstract:OBJECTIVE:Major depressive disorder (MDD) is associated with more pain complaints and an altered pain perception. Studies regarding the longitudinal relationship between depressive symptoms and pain processing have rarely been performed and have produced inconsistent results. To clarify how short-term alleviation of de...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/PSY.0b013e31815c1b5d

    authors: Kundermann B,Hemmeter-Spernal J,Huber MT,Krieg JC,Lautenbacher S

    更新日期:2008-01-01 00:00:00

  • Intravenous l-DOPA plus carbidopa in depressed patients: average evoked response, learning, and behavioral changes.

    abstract::The peripheral decarboxylase inhibitor carbidopa (L-alphamethyl-dopa-hydrazine) allowed safe intravenous administration of L-DOPA in amounts sufficient to alter cortical average evoked response (AER) and learning function in 13 depressed patients. The apparently rapid conversion of L-DOPA to dopamine, as reported from...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197603000-00003

    authors: Henry GM,Buchsbaum M,Murphy DL

    更新日期:1976-03-01 00:00:00

  • History of modern psychopharmacology: a personal view with an emphasis on antidepressants.

    abstract:OBJECTIVE:This article provides the chemical basis for the molecular modification of H1 antihistamines in the rational development of some antidepressant and antipsychotic drugs. METHODS:A review of the literature and personal experiences have been compiled. CONCLUSIONS:The contributions of many basic scientists, the...

    journal_title:Psychosomatic medicine

    pub_type: 历史文章,杂志文章

    doi:10.1097/00006842-199909000-00002

    authors: Domino EF

    更新日期:1999-09-01 00:00:00

  • Generalized anxiety disorder, major depressive disorder, and their comorbidity as predictors of all-cause and cardiovascular mortality: the Vietnam experience study.

    abstract:OBJECTIVE:To examine whether the 1-year prevalence of major depressive disorder (MDD), generalized anxiety disorder (GAD), and their comorbidity were associated with subsequent all-cause and cardiovascular disease (CVD) mortality during 15 years in Vietnam veterans. METHODS:Participants (N = 4256) were from the Vietna...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31819e6706

    authors: Phillips AC,Batty GD,Gale CR,Deary IJ,Osborn D,MacIntyre K,Carroll D

    更新日期:2009-05-01 00:00:00

  • Cortisol levels and responses to mammography screening in breast cancer survivors: a pilot study.

    abstract:OBJECTIVE:The purpose of this study was to compare baseline levels of salivary cortisol, diurnal cortisol slopes, and cortisol reactivity to a mammogram in breast cancer survivors and women without a history of cancer. METHODS:Participants were 33 breast cancer survivors (3-5 years postdiagnosis) and 21 women with no ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000088595.91705.c5

    authors: Porter LS,Mishel M,Neelon V,Belyea M,Pisano E,Soo MS

    更新日期:2003-09-01 00:00:00

  • Hostility is associated with visceral, but not subcutaneous, fat in middle-aged African American and white women.

    abstract:OBJECTIVE:To examine the cross-sectional association between hostility and measures of abdominal fat (visceral, subcutaneous) in middle-aged African American and white women. Because fat-patterning characteristics are known to differ by race, we were particularly interested in examining whether these associations were ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181ad13a7

    authors: Lewis TT,Everson-Rose SA,Karavolos K,Janssen I,Wesley D,Powell LH

    更新日期:2009-09-01 00:00:00

  • Life stresses and premature labor: real connection or artifactual findings?

    abstract::Three studies on the relationship between life stresses and premature labor were conducted. The first was a retrospective comparison of life events between a group of women who had had premature labor and a group of controls. It was carried out between 3 and 6 months after the premature delivery to neutralize possible...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198605000-00006

    authors: Omer H,Friedlander D,Palti Z,Shekel I

    更新日期:1986-05-01 00:00:00

  • Exhaustion is associated with low macrophage migration inhibitory factor expression in patients with coronary artery disease.

    abstract:OBJECTIVE:Macrophage migration inhibitory factor (MIF), a protein secreted by immune cells and the pituitary gland, may be associated with coronary artery disease (CAD) and the mental state of coronary patients. The first origin of MIF suggests positive, the second negative associations. The aim of this study was to ex...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/PSY.0b013e31802b8750

    authors: Kwaijtaal M,van der Ven AJ,van Diest R,Bruggeman CA,Bär FW,Calandra T,Appels A,Sweep FC

    更新日期:2007-01-01 00:00:00

  • Prospective examination of anxiety and depression before and during confirmed and pseudoexacerbations in patients with multiple sclerosis.

    abstract:OBJECTIVE:This study was designed to determine whether pseudoexacerbations and confirmed MS exacerbations are preceded by or concurrent with increased anxiety or depressive symptoms. METHODS:This was a secondary analysis of 121 patients with MS who were observed for 48 weeks during a randomized controlled trial. Parti...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/PSY.0b013e3182757b2b

    authors: Burns MN,Nawacki E,Siddique J,Pelletier D,Mohr DC

    更新日期:2013-01-01 00:00:00