Abstract:
BACKGROUND:Mineral trioxide aggregate (MTA) has been used in a variety of surgical and non-surgical endodontic applications. The aim of this study was to evaluate the gene expression and protein production of TNF-α, IL-1β and IL-6, as well as the gene expression of RANKL and OPG using both commercial and experimental MTA in macrophage cell cultures. METHODS:Peritoneal macrophage cell culture was performed. Viability, gene expression of cytokines, RANKL and OPG, and protein levels in experimental- and commercial-grey MTA co-cultured with peritoneal macrophages was determined by tryptan blue, real time PCR and ELISA. RESULTS:The expression of TNF-α for both commercial and experimental MTA was higher, while the expression of IL-1β and IL-6 was similar when compared to the negative control. At protein expression level, no differences were observed between the negative control and cements. RANKL did not show a significant improvement in gene expression when compared with the negative control, but OPG expression in cement samples was higher when compared to the negative control. CONCLUSIONS:This study suggests that commercial and experimental MTA promotes anti-inflammatory processes, as well as bone healing capacity.
journal_name
Aust Dent Jjournal_title
Australian dental journalauthors
Pereda GO,Fudinaga AC,Beltrán HS,Peroni LA,Stach-Machado Ddoi
10.1111/j.1834-7819.2012.01701.xsubject
Has Abstractpub_date
2012-09-01 00:00:00pages
284-91issue
3eissn
0045-0421issn
1834-7819journal_volume
57pub_type
杂志文章abstract:BACKGROUND:Easily applied, age-specific standards are useful in assisting clinicians to decide whether the extent of tooth wear observed in a given patient at a specific age is acceptable or whether intervention is indicated. METHOD:A simple method of scoring tooth wear and previously established mathematical relation...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2003.tb00041.x
更新日期:2003-12-01 00:00:00
abstract::It is over 100 years since GV Black gathered together most of the knowledge then current on the caries process and set clear parameters for the discipline of operative dentistry. His four-volume treatise set standards that were relevant for the times and, in fact, were so well described that they remained dominant in ...
journal_title:Australian dental journal
pub_type: 历史文章,杂志文章,评审
doi:10.1111/j.1834-7819.2007.tb00500.x
更新日期:2007-12-01 00:00:00
abstract::The young dental graduate expects to deliver a certain standard of health care to the community. It is likely that both the standard of care required by the Australian people and the proportion of the population seeking treatment will increase in the coming decades. The dental profession has a responsibility to meet t...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1978.tb03537.x
更新日期:1978-08-01 00:00:00
abstract::A biochemical identification scheme has been produced that allows for the differentiation of nine distinct species within the Streptococcus sanguis group. The species are S. sanguis, S. gordonii, S. crista, S. oralis, S. parasanguis, S. defectivus, S. adjacens and S. mitis, which have been previously described, and a ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1996.tb05922.x
更新日期:1996-04-01 00:00:00
abstract::A case of central fibroma involving the mandible in a 58 year old woman is described. There was slight swelling of the left cheek and bone-hard bulging was detected on palpation but the patient had not complained of the swelling. The lesion was removed under general anaesthesia and then examined histopathologically. T...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1999.tb00214.x
更新日期:1999-06-01 00:00:00
abstract:BACKGROUND:The current retrospective cross-sectional study investigated 5-18-year treatment outcomes in subjects who did not complete a recommended course of periodontal therapy. METHODS:Sixty-five subjects who voluntarily discontinued therapy were recalled. The subjects' demographic data and dental history since disc...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/adj.12440
更新日期:2017-06-01 00:00:00
abstract::It is widely accepted that all dentists should have a thorough understanding of the muscles involved in moving or stabilizing the mandible. However, there is still much discussion regarding the influence of the mandibular muscles on normal facial growth and dental development, as well as on orthodontic treatment and p...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/adj.12481
更新日期:2017-03-01 00:00:00
abstract::Electromyographic analysis was carried out prior to occlusal equilibration for patients who had some form of TMJ dysfunction and again after treatment. The results were compared with similar analyses for patients without any symptoms of dysfunction (controls) and for patients who had been wearing some kind of occlusal...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1978.tb03567.x
更新日期:1978-12-01 00:00:00
abstract:BACKGROUND:The use of all-in-one resin-based adhesives in clinical practice has continued to increase. The aim of this study was to evaluate retention and marginal staining of a HEMA-free all-in-one adhesive Go! (SDI, Australia) and Ice resin composite in non-carious cervical lesions (NCCLs). METHODS:Forty-one restora...
journal_title:Australian dental journal
pub_type: 临床试验,杂志文章
doi:10.1111/j.1834-7819.2011.01370.x
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Trismus and jaw pain are not only caused by temporomandibular disorders (TMD), but also by various pathologies, namely infection, trauma, or neoplasms. TMD-like symptoms, as a result of the pathologies, may be confusing to a clinician. This paper reports two cases of chronic dental infection mimicking TMD. ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2002.tb00305.x
更新日期:2002-03-01 00:00:00
abstract::The compressive and tensile (by diametral compression) strengths of amalgams prepared from fifteen conventional and higher copper alloys are compared and the rate at which these amalgams develop strength is investigated. Alloys of the single melt high copper type generally possess the greatest strength at all times of...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1979.tb02933.x
更新日期:1979-08-01 00:00:00
abstract::This article is a review of the recent literature pertaining to the oral sequelae of eating disorders (EDs). Dentists are recognized as being some of the first health care professionals to whom a previously undiagnosed eating disorder patient (EDP) may present. However, despite the prevalence (up to 4 per cent) of suc...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/j.1834-7819.2005.tb00079.x
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND:The aim of this study was to document the three main indicators of severe periodontal destruction and to evaluate factors associated with those indicators in an urban Indigenous population in Australia. METHODS:A cross-sectional survey of a convenience sample of Aboriginal adults from an Australian urban ar...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/adj.12138
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Workforce development is acritical factor allowing delivery on government health priorities. Against a backdrop of increasingdemand for dental therapists being significantly higher than the levels of recruitment, it is widely acknowledged that rural and remote areas (having greater recruitment and retention ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2007.tb00461.x
更新日期:2007-03-01 00:00:00
abstract::The patient in this report is a young boy with hypohydrotic ectodermal dysplasia. His case is exceptional in that anodontia was complete in both deciduous and permanent dentitions. A brief review of this condition is presented along with the prosthetic management of the case which emphasizes the need for regular modif...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1990.tb05873.x
更新日期:1990-04-01 00:00:00
abstract::The radiopacity of 33 commercially available composite materials was measured in terms of their equivalent thickness of an aluminum alloy per unit thickness of material. The theoretical significance of this definition was discussed. The radiopacities were found to vary by more than an order of magnitude. Although near...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1981.tb02443.x
更新日期:1981-04-01 00:00:00
abstract::The F concentrations in plaque and in underlying enamel were determined in a sample of 99 schoolchildren aged 8.4 years (S.D. = 0.37), comprising four groups, exposed life-long to contrasting concentrations of F in the water (range less than or equal to 0.12 ppm to 2.8 ppm) and to supplements of 350 mg F/kg domestic s...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1982.tb02465.x
更新日期:1982-12-01 00:00:00
abstract:BACKGROUND:Psychosomatic factors and their association with dermatological disorders are well recognized, yet their importance in oral lichen planus (OLP) is still debated. This study was done to determine the importance of psychosocial stressors in patients with OLP. METHODS:An analytical age-sex matched double contr...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2004.tb00072.x
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Titanium is generally considered a safe metal to use in implantation but some studies have suggested that particulate titanium may cause health problems either at the site overlying the implant or in distant organs, particularly after frictional wear of a medical prosthesis. It was the purpose of this invest...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2002.tb00331.x
更新日期:2002-09-01 00:00:00
abstract::The aim of this study was to investigate the current published work relating to the clinical benefits of the use of systemic azithromycin as an adjunct to non-surgical periodontal therapy. A published work search of PubMed, EMBASE and Cochrane Register of Controlled Trials up to 27 April 2016 was undertaken. The large...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/adj.12448
更新日期:2017-03-01 00:00:00
abstract::Dental biomaterials are widely used in all areas of routine dental practice. There are mainly two methods for their application. Firstly, dental biomaterials are placed into living tissues, such as teeth, to fill the space. Secondly, dental devices such as crown and bridge restorations and dentures are fabricated usin...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/j.1834-7819.2010.01300.x
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:The cleaning of endodontic and all dental instruments prior to sterilization is a prerequisite for their processing for re-use. This study aimed to develop a clinically practical cleaning protocol for rotary nickel-titanium (NiTi) endodontic files prior to sterilization. METHODS:Cleaning experiments were co...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2004.tb00045.x
更新日期:2004-03-01 00:00:00
abstract::A primary preventive dental programme targeting adolescents living in non-fluoridated areas of Victoria, Australia was evaluated for a three-year period. The programme comprised annual placement or replacement/repair of fissure sealants combined with a weekly 0.2 per cent sodium fluoride mouthrinse and was evaluated i...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1997.tb06082.x
更新日期:1997-12-01 00:00:00
abstract::The effects of a number of factors on creep in dental amalgam was investigated. The factors studied were the delayed time between mixing and packing, the packing technique, the alloy system and the annealing or ageing of specimens at 37 degrees C for one and 190 days. The delayed time and the alloy system factors as w...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1977.tb04490.x
更新日期:1977-06-01 00:00:00
abstract:BACKGROUND:The erosive potential of wine on teeth may be modified by the buffering capacity of saliva. This potential effect was studied for three different wines in vitro and in vivo. METHODS:The buffering capacity was studied in vitro by stepwise addition of small volumes of a dry white wine, a medium sweet white wi...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2009.01124.x
更新日期:2009-09-01 00:00:00
abstract::Malposed mandibular and maxillary premolars and canines often cause great difficulties in removal. The ways in which these procedures are accomplished are described in detail. ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1975.tb04356.x
更新日期:1975-06-01 00:00:00
abstract::The availability of improved ceramic materials, bonding techniques, new technology and issues of amalgam safety have led to a revival of interest in ceramic inlays in dentistry over the past ten years. Clinical studies have been carried out during this time using various evaluation techniques to assess the clinical pe...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/j.1834-7819.1999.tb00217.x
更新日期:1999-09-01 00:00:00
abstract::From records of 32 067 dentate persons from low fluoride communities in South Yorkshire, England, clinical dental caries has been scored at the distal and mesial sites of permanent canines, first and second premolars, and first and second molars, in relation to age. For those teeth with distal or mesial caries or both...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1981.tb05225.x
更新日期:1981-10-01 00:00:00
abstract::Various methods, with a variety of materials, exist for restoring carious primary teeth. Successful restoration of primary teeth is dependent on accurate diagnosis, knowledge of the caries process, knowledge of dental materials, and treatment choice. The purpose of this evidence-based review is to present evidence tha...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/adj.12682
更新日期:2019-06-01 00:00:00
abstract::This paper presents some information, derived by questionnaire, on the social characteristics and background of 1148 first-year dental students at the University of Sydney for the years 1976-1985. Student entry age was 19.4 years; 27 per cent were female; 36 per cent of fathers and 24 per cent of mothers were professi...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1992.tb00764.x
更新日期:1992-10-01 00:00:00