Swelling Gliotransmission by SWELL1 Channels.

Abstract:

:Astrocytes release glutamate, which can modulate nearby synapses, but how this release is accomplished remains debated. In this issue of Neuron, Yang et al. (2019) show that the volume-regulated anion channel Swell1 in astrocytes mediates the release of glutamate and impacts synaptic transmission, learning and memory, and neurotoxicity.

journal_name

Neuron

journal_title

Neuron

authors

Kofuji P,Araque A

doi

10.1016/j.neuron.2019.05.005

subject

Has Abstract

pub_date

2019-05-22 00:00:00

pages

711-713

issue

4

eissn

0896-6273

issn

1097-4199

pii

S0896-6273(19)30430-1

journal_volume

102

pub_type

评论,杂志文章

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