The evolution of pigeon paramyxovirus type 1 (PPMV-1) in Great Britain: a molecular epidemiological study.

Abstract:

:Newcastle disease (ND), caused by virulent strains of avian paramyxovirus type 1 (APMV-1), is considered throughout the world as one of the most important animal diseases. For over three decades now, there has been a continuing panzootic caused by a variant virulent APMV-1 strain, so-called pigeon paramyxovirus type 1 (PPMV-1), primarily in racing pigeons, which has also spread to wild birds and poultry. PPMV-1 isolations have been made in Great Britain every year since 1983. In this study, we have completed a comparative phylogenetic analysis based on a 374 nucleotide section of the fusion protein gene of 63 isolates of PPMV-1 that were isolated over a 26-year period; 43 of these were sequenced for this study. Phylogenetic analysis of these sequences revealed that all were closely related and placed in the genetic sublineage 4b (VIb), subdivision 4biif.

journal_name

Transbound Emerg Dis

authors

Aldous EW,Fuller CM,Ridgeon JH,Irvine RM,Alexander DJ,Brown IH

doi

10.1111/tbed.12006

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

134-9

issue

2

eissn

1865-1674

issn

1865-1682

journal_volume

61

pub_type

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