Efficacy and Safety of Enoxaparin for Prophylaxis of Postoperative Venous Thromboembolism After Esophagectomy: A Single-center Prospective Randomized Controlled Phase II Study.

abstract：:Human papillomaviruses (HPV) and their role in carcinogenesis have been the subject of extensive investigation Specific types of HPV have been associated with cervical carcinoma HPV 16 and 18 are mainly associated with malignant progression and considered "high risk" viruses Using Southern blot analysis and in situ hy...

journal_title：Anticancer research

authors： Vassilandonopoulou G,Panotopoulou E,Fotiou S,Tserkezoglou A,Machera E,Kottaridis S

更新日期：1997-01-01 00:00:00

abstract：UNLABELLED:The aim of the study was to evaluate the prognostic value of vascular endothelial growth factor C (VEGF-C) and VEGF-D expression in stage II, grade 2 and 3, ductal breast cancer patients. PATIENTS AND METHODS:The immunohistochemical staining of 98 tumor samples and 5- and 10-year overall (OS) and disease-fr...

journal_title：Anticancer research

authors： Gisterek I,Matkowski R,Koźlak J,Duś D,Lacko A,Szelachowska J,Kornafel J

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Chronic lymphocytic leukemia (CLL) is characterized by a clonal accumulation of neoplastic lymphocytes, indicating disruption of apoptosis. PATIENTS AND METHODS:Differential methylation hybridization analysis was performed to identify novel target genes silenced by CpG island methylation in patients with CL...

journal_title：Anticancer research

authors： Schmidt-Wolf IG,Plass C,Byrd JC,Frevel K,Pietsch T,Waha A

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND/AIM:An active metabolite of the anti-leukemia agent clofarabine (Cl-F-ara-A) is an intracellular triphosphate form, Cl-F-ara-ATP. Monitoring this active form could provide crucial information for optimizing treatment regimens based on Cl-F-ara-A. A simple, isocratic HPLC method was developed. MATERIALS AND ...

journal_title：Anticancer research

authors： Yamauchi T,Nishi R,Ueda T

更新日期：2011-09-01 00:00:00

abstract：:The effect of some new antiestrogens (ICI 164384, ICI 182780, Ly 133314 and Ly 117018) on the growth of a panel of breast cancer cell lines (MDA-MB 231, BT20, MCF7 and T47D) was studied. Their antiestrogenic activity was investigated in the presence of a physiologic concentration of estradiol and compared with the eff...

journal_title：Anticancer research

authors： Coradini D,Biffi A,Cappelletti V,Di Fronzo G

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND/AIM:Metabolomics is widely used for biomarker discovery, but conventional mass-spectrometry extraction procedures lose the spatial localization of metabolites. In this study, we directly analyzed breast carcinoma tissues embedded in frozen tissue microarrays (fTMAs) using MALDI mass-spectrometry imaging (MAL...

journal_title：Anticancer research

authors： Torata N,Kubo M,Miura D,Ohuchida K,Mizuuchi Y,Fujimura Y,Hayakawa E,Kai M,Oda Y,Mizumoto K,Hashizume M,Nakamura M

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND/AIM:Since antigenic peptides of the cancer-associated antigens presented on human leukocyte antigen (HLA) molecules are recognized by specific cytotoxic T-lymphocytes, they have the potential to becoming effective peptide vaccines for cancer immunotherapy. MATERIALS AND METHODS:Peptides binding to HLA-A*020...

journal_title：Anticancer research

authors： Kamata Y,Kuhara A,Iwamoto T,Hayashi K,Koido S,Kimura T,Egawa S,Homma S

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The mouse epidermal JB6 cell system is a model for studying tumor promotion. We used the JB6 Cl 41 cell line to examine the mechanism of the anti-tumor-promoting effect of tetrandrine, an alkaloid isolated from Stephania tetrandra S Moore. MATERIALS AND METHODS:The anti-tumor-promoting effect of tetrandrine...

journal_title：Anticancer research

authors： Nomura M,Yamazaki R,Takaya M,Kikuchi M,Takahashi-Nishioka T,Akiyama K,Akiyama N,Moritani S,Kobayashi S

更新日期：2007-09-01 00:00:00

abstract：UNLABELLED:The aim of this study was to evaluate the utility of HER2/neu ECD concentration as a marker of the efficacity of clinical response to Herceptin. PATIENTS AND METHODS:Iterative measurements of HER2/neu ECD (ELISA c-erbB2/c-neu Rapid Format Elisa kit QIA10 Calbiochem) concentrations in 45 patients treated wit...

journal_title：Anticancer research

authors： Gauchez AS,Colonna M,Brand FX,Ravanel N,Pasquier D,Payan R,Mousseau M

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Expression of novel stem cell-associated marker human embryonic stem cell 77 (HES77) was studied in rectal neuroendocrine tumors (NETs), which comprise 10 to 15% of gastroenteropancreatic NETs, some with metastatic potential. MATERIALS AND METHODS:WHO 2010 classification was applied, and immunohistochemical...

journal_title：Anticancer research

authors： Jernman J,Hagström J,Mäenpää H,Välimäki MJ,Haapasalo H,Nilsson O,Fermér C,Haglund C,Arola J

更新日期：2015-07-01 00:00:00

abstract：:The antitumor effects of the somatostatin structural derivative TT-232 in different rodent and xenograft tumor models are summarized in this report. TT-232 had previously been shown to inhibit the proliferation of a large number of cancer cell lines in vitro and reduce the size of different tumors in animal models in ...

journal_title：Anticancer research

authors： Tejeda M,Gaál D,Hullán L,Hegymegi-Barakonyi B,Kéri G

更新日期：2006-09-01 00:00:00

abstract：:The magnetic resonance (MR) findings in malignant melanoma of soft tissues, also called clear cell sarcoma of tendons and aponeuroses, have been described as a focal abnormality with a specific MR pattern of increased signal intensity (relative to normal muscle) on T1 weighted sequences and variably decreased signal i...

journal_title：Anticancer research

authors： Gandolfo N,Martinoli C,Cafiero F,Peressini A,Nicolò M,Dellachà A,Derchi LE

更新日期：2000-09-01 00:00:00

abstract：:The local growth and metastatic potential of colorectal cancer is the outcome of a dynamic balance between cancer cells and the immune system, at both a local and systemic level, summarized as the "seed and soil" hypothesis. Until recently, the staging and treatment approaches for colorectal cancer appeared to be orie...

journal_title：Anticancer research

authors： Seretis F,Seretis C,Youssef H,Chapman M

更新日期：2014-05-01 00:00:00

abstract：AIM:To assess the correlation between advanced non-small cell lung cancer (NSCLC) with or without pulmonary lymphangitic carcinomatosis (PLC) and fluorodeoxyglucose (FDG) uptake and its effect on survival outcomes. PATIENTS AND METHODS:We retrospectively reviewed 157 patients with NSCLC. The mean and maximum standardi...

journal_title：Anticancer research

authors： Ooi H,Chen CY,Hsiao YC,Huang WS,Hsieh BT

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND/AIM:Triple-negative breast cancers (TNBC) lack expression of three important receptors, and have limited treatment options. High expression of junctional adhesion molecule-A (JAM-A) has been linked with aggressive tumor phenotypes including TNBC. This study aimed to evaluate the bioactivity of a JAM-A-down-r...

journal_title：Anticancer research

authors： Vellanki SH,Cruz RGB,Richards CE,Smith YE,Hudson L,Jahns H,Hopkins AM

更新日期：2019-03-01 00:00:00

abstract：:Membrane permeability is a critical parameter which must be assessed in the course of new potential anticancer drug studies. Flow cytometry allows us to monitor the permeability status of living cells through the measurement of fluorochrome retention; conventionally this is done using fluorescein diacetate or Hoechst3...

journal_title：Anticancer research

authors： Leonce S,Cudennec CA

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Genomic imprinting is associated with many human diseases, including various types of cancers, however, no studies on gene imprinting are related to squamous cell carcinoma of the head and neck (SCCHN) directly. MATERIALS AND METHODS:In this study, the expression of a panel of 15 imprinted genes in cancerou...

journal_title：Anticancer research

authors： Hsu CM,Lin PM,Lin HC,Lai CC,Yang CH,Lin SF,Yang MY

更新日期：2016-05-01 00:00:00

abstract：:A universal intracellular factor, the "M phase-promoting factor" (MPF), triggers the G2/M transition of the cell cycle in all organisms. In late G2, it is present as an inactive complex of tyrosine-phosphorylated p34cdc2 and unphosphorylated cyclin Bcdc13. In M phase, its activation as an active MPF displaying histone...

journal_title：Anticancer research

authors： Baratte B,Meijer L,Galaktionov K,Beach D

更新日期：1992-05-01 00:00:00

abstract：:The high glucose consumption of tumour cells has been well known since Warburg's investigations. Nevertheless, the reason for this phenomenon is still a matter of speculation. Glucose uptake of tumour cells is mainly mediated by GLUT1. In this study, the question of whether glucose uptake as well as expression of GLUT...

journal_title：Anticancer research

authors： Hauptmann S,Grünewald V,Molls D,Schmitt WD,Köbel M,Kriese K,Schürmann A

更新日期：2005-09-01 00:00:00

abstract：:We examined the antitumor effect of lipopolysaccharide extracted from Pantoea agglomerans, a Gram-negative bacterium, using intradermal administration on murine syngeneic tumors, Meth A fibrosarcoma, MH134 hepatoma and Lewis lung (LL) carcinoma. The latter two tumors are known to be relatively low in immunogenicity, h...

journal_title：Anticancer research

authors： Inagawa H,Nishizawa T,Noguchi K,Minamimura M,Takagi K,Goto S,Soma G,Mizuno D

更新日期：1997-05-01 00:00:00

abstract：:A sarcomatoid carcinoma cell line (SAR-HCV) was established from a malignant liver lesion of a patient infected with hepatitis C virus. SAR-HCV cells were successfully xenografted in SCID mice. Vimentin was strongly positive in cultured SAR-HCV cells, the primary tumour lesion and the xenografts. Hepatocyte paraffin 1...

journal_title：Anticancer research

authors： Tai DI,Shen YJ,Weng WH,Chen HW,Kang CC,Chen TC,Liao SK

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Human neuroblastoma and medulloblastoma express abnormal ganglioside patterns especially GD2 and GM2 which are important for tumour growth. We tested the effects of L-cycloserine (L-CS), a potent inhibitor of synthesis of glycosphingolipids, on the growth, viability and expression of GD2 and GM2 in neuroblas...

journal_title：Anticancer research

authors： Cinatl J Jr,Cinatl J,Kotchetkov R,Pouckova P,Vogel JU,Rabenau H,Michaelis M,Kornhuber B

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND/AIM:We previously identified that promoter DNA methylation of cysteine dioxygenase type 1 (CDO1) and homeobox only protein homeobox (HOPX) were both cancer specific, and have a clinical potential as prognostic biomarkers in breast cancer (BC). The present study compared the differential prognostic relevance ...

journal_title：Anticancer research

authors： Tanaka Y,Kosaka Y,Waraya M,Yokota K,Harada H,Kaida T,Kikuchi M,Minatani N,Nishimiya H,Katoh H,Sengoku N,Watanabe M,Yamashita K

更新日期：2019-05-01 00:00:00

abstract：:Malignant gliomas are often treated with cisplatin (cis-diamminedichloroplatinum(II), CDDP) and radiation but results remain unsatisfactory. To investigate whether CDDP induces radioresistance in glioma, T98G human glioblastoma cells were pretreated 5 times with 10(-6)M CDDP for 24 hours and then the sensitivity of wi...

journal_title：Anticancer research

authors： Poppenborg H,Münstermann G,Knüpfer MM,Hotfilder M,Hacker-Klom U,Wolff JE

更新日期：1997-03-01 00:00:00

abstract：:This review focuses on the relationship between pre-treatment immune parameter values and outcome of immunotherapy of cancer patients. The evidence presented in this review suggests that there is a relationship between pre-treatment immune parameter values and survival of cancer patients treated with immunotherapy. Tu...

journal_title：Anticancer research

authors： Characiejus D,Jacobs JJ,Pašukonienė V,Kazlauskaitė N,Danilevičiūtė V,Mauricas M,Den Otter W

更新日期：2011-02-01 00:00:00

abstract：:Flunarizine, a calcium-antagonist drug that binds to calmodulin, was found to inhibit the migration of both B16 melanoma cells and M5076 macrophage-like cancer cells. The migration movement, both under agarose and through a polycarbonate filter membrane, was impaired by the drug. In M5076 macrophage-like cells Fc-depe...

journal_title：Anticancer research

authors： Sezzi ML,De Luca G,Materazzi M,Bellelli L

更新日期：1985-05-01 00:00:00

abstract：:Telomeres, the tandem-repeated hexamers at the termini of mammalian chromosomes, form protective complexes in association with specific proteins that together with telomerase, a specialised telomere-synthesizing enzyme, regulate telomere length. Telomere shortening is associated with cellular senescence and is implica...

journal_title：Anticancer research

authors： Bekaert S,De Meyer T,Van Oostveldt P

更新日期：2005-07-01 00:00:00

abstract：:A 70-year-old man with a growing liver tumor had undergone subtotal gastrectomy with pancreaticoduodenectomy for gastric cancer (T4b P0 H0 N1, Stage IIIB) 30 months before admission to our hospital. Enhanced computed tomography revealed two hypervascular nodules in segments 4 and 8. After histological diagnosis of sma...

journal_title：Anticancer research

authors： Kinoshita K,Beppu T,Miyata T,Kuramoto K,Yoshida Y,Umesaki N,Kitano Y,Nakagawa S,Okabe H,Nitta H,Imai K,Hayashi H,Yamashita YI,Komori H,Horino K,Misumi A,Baba H

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Principal caregivers (PCs) of cancer patients experience high levels of stress that may significantly impact their quality of life (QoL). PCs' QoL during early phases of the disease (when patients were still on chemotherapy) were assessed. PATIENTS AND METHODS:The PCs of all patients meeting the inclusion c...

journal_title：Anticancer research

authors： Pellegrino R,Formica V,Portarena I,Mariotti S,Grenga I,Del Monte G,Roselli M

更新日期：2010-11-01 00:00:00

abstract：:Brain tumors were induced in inbred Fischer rats (F344) by administration of methylnitrosourea in the drinking water. One of the induced tumors, a pleomorphic glioma (78-219), was established in vitro and propagated as 78FR-G-219 permanent cell line. The tumorigenicity of the established line was investigated by intra...

journal_title：Anticancer research

authors： Stavrou D,Bilzer T,Anzil AP,Hultén M,Kaldrymidou E

更新日期：1981-01-01 00:00:00