Studies of the leukemic cell associated antigen(s) in mice with myeloid leukemia (Graffi), using the immunoperoxidase techniques.

Abstract:

:Thymus, spleen and lymph nodes from myeloid leukemic mice (Graffi) were examined by light and electron microscope using immunoperoxidase techniques. As immune sera autologous sera were applied. The percentage of the labeled leukemic cells ranged from 30 to 60. It was established that leukemic cell associated antigen(s) was located mainly on the plasma and nuclear membranes. Occasionally this antigen(s) was observed in some areas of the endoplasmic reticulum, on separate cytoplasmic vesicles, on the budding viruses and on the chromatin. In addition, weakly expressed antigen(s) was located in cytosol. The mature virus particles were not labeled with peroxidase.

journal_name

Neoplasma

journal_title

Neoplasma

authors

Yantchev IK

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

397-404

issue

4

eissn

0028-2685

issn

1338-4317

journal_volume

26

pub_type

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