Abstract：
:The accelerated elucidation of three-dimensional structures of protein complexes, both natural and designed, is providing new examples of large supramolecular assemblies with intriguing shapes. Those with high symmetry - based on the geometries of the Platonic solids - are particularly notable as their innately closed forms create interior spaces with varying degrees of enclosure. We survey known protein assemblies of this type and discuss their geometric features. The results bear on issues of protein function and evolution, while also guiding novel bioengineering applications. Recent successes using high-symmetry protein assemblies for applications in interior encapsulation and exterior display are highlighted.
journal_name
Curr Opin Struct Bioljournal_title
Current opinion in structural biologyauthors
Cannon KA,Ochoa JM,Yeates TOdoi
10.1016/j.sbi.2019.03.008subject
Has Abstractpub_date
2019-04-01 00:00:00pages
77-84eissn
0959-440Xissn
1879-033Xpii
S0959-440X(18)30199-4journal_volume
55pub_type
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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