Extramedullary disease in multiple myeloma - controversies and future directions.

Abstract:

:Extramedullary disease of multiple myeloma (EM) remains a treatment challenge even in the era of new drugs. While many reports analyzing various aspects of EM have been published, mechanism of EM development has not been clarified yet. This review summarizes current knowledge about this clinical entity, including its history, diagnostics, imaging methods, incidence, prognosis, current treatment options, risk factors and known molecular mechanisms that might be involved in pathogenesis of EM.

journal_name

Blood Rev

journal_title

Blood reviews

authors

Sevcikova S,Minarik J,Stork M,Jelinek T,Pour L,Hajek R

doi

10.1016/j.blre.2019.04.002

subject

Has Abstract

pub_date

2019-07-01 00:00:00

pages

32-39

eissn

0268-960X

issn

1532-1681

pii

S0268-960X(18)30096-1

journal_volume

36

pub_type

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