Desmoplasia in pancreatic cancer. Can we fight it?

abstract：:Background. Little data on directly comparing chemoradiotherapy with observation has yet been published in the setting of adjuvant therapy for resected gastric cancer who underwent D2 lymphadenectomy. The present indirect comparison aims to provide more evidence on comparing the two approaches. Methods. We conducted a...

journal_title：Gastroenterology research and practice

authors： Yang Q,Wei Y,Chen YX,Zhou SW,Jiang ZM,Xie DR

更新日期：2013-01-01 00:00:00

abstract：Background and Aims:Thiopurines are commonly used for treating ulcerative colitis (UC), despite the fact that controlled evidence supporting their efficacy is limited. The aim of this study was to evaluate the long-term outcome of thiopurines as maintenance therapy in a large cohort of UC patients. Methods:All UC pati...

journal_title：Gastroenterology research and practice

authors： Pugliese D,Aratari A,Festa S,Ferraro PM,Monterubbianesi R,Guidi L,Scribano ML,Papi C,Armuzzi A

更新日期：2018-10-03 00:00:00

abstract：:Despite extensive research, alcohol remains one of the most common causes of liver disease in the United States. Alcoholic liver disease (ALD) encompasses a broad spectrum of disorders, including steatosis, steatohepatitis, and cirrhosis. Although many agents and approaches have been tested in patients with ALD and in...

journal_title：Gastroenterology research and practice

authors： Li F,Duan K,Wang C,McClain C,Feng W

更新日期：2016-01-01 00:00:00

abstract：:Laparoscopic appendectomy has become favored over open surgical methods for its association with decreased postoperative pain, more rapid return to daily activities, and improved cosmetic results. Mini-incision appendectomy was being performed in our clinic for a long time especially in patients with noncomplicated ap...

journal_title：Gastroenterology research and practice

authors： Özsan İ,Karabuğa T,Yoldaş Ö,Alpdoğan Ö,Aydın Ü

更新日期：2014-01-01 00:00:00

abstract：Introduction:Abdominal and anorectal disorders may be the cause of clinical decompensation in neutropenic febrile patients, particularly those with hematologic diseases. Infection is a cause for concern for the colorectal surgeon. Some conditions have few manifestations and can lead to death within a short period of ti...

journal_title：Gastroenterology research and practice

authors： Perazzoli C,Parra RS,Feitosa MR,Sfoggia E,Simões BP,Rocha JJR,Féres O

更新日期：2019-03-24 00:00:00

abstract：:Background. The role of endoglin in the Dukes B rectal cancer is still unexplored. The aim of this study was to examine the expression of endoglin (CD105) in resected rectal cancer and to evaluate the relationship between microvessels density (MVD), clinicopathological factors, and survival rates. Methods. The study i...

journal_title：Gastroenterology research and practice

authors： Martinovic Z,Kovac D,Martinovic M

更新日期：2015-01-01 00:00:00

abstract：:Resveratrol is a natural polyphenol studied for its possible protective properties in inflammatory bowel diseases. Moreover, it has been shown to interact with estrogen receptors. In the present study, we aimed to investigate possible diverse effects of resveratrol on female and male mice in DSS-induced colitis. Thirt...

journal_title：Gastroenterology research and practice

authors： Wagnerova A,Babickova J,Liptak R,Vlkova B,Celec P,Gardlik R

更新日期：2017-01-01 00:00:00

abstract：:Background. Apoptotic rates in peripheral blood lymphocytes can predict radiation induced normal tissue toxicity. We studied whether apoptosis in lymphocytes has a prognostic value for therapy outcome. Methods. Lymphocytes of 87 rectal cancer patients were ex vivo irradiated with 2 Gy, 8 Gy, or a combination of 2 Gy i...

journal_title：Gastroenterology research and practice

authors： Winkler S,Hoppe P,Haderlein M,Hecht M,Fietkau R,Distel LV

更新日期：2016-01-01 00:00:00

abstract：:Objective. Here, we aim to investigate the microRNA (miR) profiling in human gastric cancer (GC). Methods. Tumoral and matched peritumoral gastric specimens were collected from 12 GC patients who underwent routine surgery. A high-throughput miR sequencing method was applied to detect the aberrantly expressed miRs in a...

journal_title：Gastroenterology research and practice

authors： Zhang T,Liu C,Huang S,Ma Y,Fang J,Chen Y

更新日期：2017-01-01 00:00:00

abstract：Background:We conducted this meta-analysis to compare the efficacy and safety of simultaneous hepatectomy and splenectomy (HS) with hepatectomy alone (HA) in patients with hepatocellular carcinoma (HCC) and hypersplenism. Materials and Methods:A systematic search was conducted in PubMed, Embase, Cochrane Library, and ...

journal_title：Gastroenterology research and practice

authors： Liu X,Chen Z,Yu M,Zhou W,Zhi X,Li T

更新日期：2019-08-14 00:00:00

abstract：:Background. Single nucleotide polymorphisms (SNPs) in genes encoding microRNAs may play important role in the development of gastric cancer. It has been reported that common SNPs rs2910164 in miR-146a and rs11614913 in miR-196a2 are associated with susceptibility to gastric cancer. The published results remain inconcl...

journal_title：Gastroenterology research and practice

authors： Ni Q,Ji A,Yin J,Wang X,Liu X

更新日期：2015-01-01 00:00:00

abstract：:Purpose. Endoscopic ultrasound (EUS) permits the detailed visualization of clinically significant features of portal hypertension; however, it is an invasive procedure that is not widely available. The aim of this cross-sectional study was to determine whether a correlation exists between the features of portal hypert...

journal_title：Gastroenterology research and practice

authors： Wiechowska-Kozłowska A,Zasada K,Milkiewicz M,Milkiewicz P

更新日期：2012-01-01 00:00:00

abstract：:Introduction. In a previously published article the authors reported the long-term follow-up results in 138 consecutive patients with gallstones and common bile duct (CBD) stones who underwent laparoscopic transverse choledochotomy (TC) with T-tube biliary drainage and laparoscopic cholecystectomy (LC). Aim of this st...

journal_title：Gastroenterology research and practice

authors： Quaresima S,Balla A,Guerrieri M,Lezoche G,Campagnacci R,D'Ambrosio G,Lezoche E,Paganini AM

更新日期：2016-01-01 00:00:00

abstract：:The incidence of inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), has increased in pediatric populations over the last decade. Patients diagnosed during childhood often survive well into adulthood, and therefore their healthcare requires transfer to an adult gastroenterolo...

journal_title：Gastroenterology research and practice

authors： Bollegala N,Nguyen GC

更新日期：2015-01-01 00:00:00

abstract：:This study was aimed at investigating the effect of baicalin on experimental cholesterol gallstones in mice. The mouse gallstone model was induced by feeding with a lithogenic diet, and cholesterol stones were found in the gallbladder. The lithogenic diet caused elevation of triglycerides, cholesterol, and low-density...

journal_title：Gastroenterology research and practice

authors： Chen G,Wu S

更新日期：2020-04-21 00:00:00

abstract：Background:The aim of this study was to evaluate the risk of development of colorectal adenomas in patients with colorectal cancer (CRC) with and without colonic diverticulosis. Methods:We performed a retrospective cohort study that included patients with CRC between 2008 and 2011. All patients underwent preoperative ...

journal_title：Gastroenterology research and practice

authors： Kim YJ,Kim DB,Chung WC,Lee JM

更新日期：2019-05-20 00:00:00

abstract：Background:Nonselective β-blockers (NSBB) have been associated with increased incidence of paracentesis-induced circulatory dysfunction (PICD) and reduced survival in patients with cirrhosis and refractory ascites. Aim:To prospectively evaluate a hemodynamic response to NSBB in cirrhotics listed for liver transplantat...

journal_title：Gastroenterology research and practice

authors： Ferrarese A,Tikhonoff V,Casiglia E,Angeli P,Fasolato S,Faggian D,Zanetto A,Germani G,Russo FP,Burra P,Senzolo M

更新日期：2018-05-09 00:00:00

abstract：:Survival rates among HIV patients have significantly improved since the introduction of antiretroviral therapy (ART) in HIV management. However, persistent disease progression and clinical complications in virally suppressed individuals point to additional contributing factors other than HIV replication; microbial tra...

journal_title：Gastroenterology research and practice

authors： Nwosu FC,Avershina E,Wilson R,Rudi K

更新日期：2014-01-01 00:00:00

abstract：:Activation of innate immunity is associated with the development of liver disease, including non-alcoholic fatty liver disease (NAFLD). In the innate immune system, Toll-like receptors (TLRs) are sensors that recognize bacterial and viral components such as lipopolysaccharide, bacterial DNA, and peptidoglycan. Recent ...

journal_title：Gastroenterology research and practice

authors： Miura K,Seki E,Ohnishi H,Brenner DA

更新日期：2010-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2014/904307.]. ...

journal_title：Gastroenterology research and practice

authors： Müller KE,Lakatos PL,Papp M,Veres G

更新日期：2015-01-01 00:00:00

abstract：Background/Aim:Endoscopic balloon dilation (EBD) has been effective for small-bowel strictures in patients with Crohn's disease (CD). However, its efficacy and indication for small-bowel strictures in non-CD patients have not been established. This study evaluated the clinical efficacy and safety of EBD for small-bowel...

journal_title：Gastroenterology research and practice

authors： Tsuboi A,Oka S,Tanaka S,Iio S,Otani I,Kunihara S,Hayashi R,Chayama K

更新日期：2019-05-06 00:00:00

abstract：:The aim of this study was to use functional magnetic resonance imaging (BOLD-fMRI) to investigate the activated region associated with visceral pain in the brains of infant rats in a model of IBS. Sixteen newborn rats were randomized into an IBS model group and a control group. Those in the IBS group were separated fr...

journal_title：Gastroenterology research and practice

authors： Zhu X,Zhu X,Chen W,Chen J

更新日期：2014-01-01 00:00:00

abstract：:Irritable bowel syndrome (IBS) is a gastrointestinal disorder linked to disturbances in the gut-brain axis. Visceral hypersensitivity and pain are hallmarks of IBS and linked to the physiological and psychological burden and to the nonadaptive coping with stress. Cognitive-behavioral therapy (CBT) for IBS has proven e...

journal_title：Gastroenterology research and practice

authors： Edebol-Carlman H,Ljótsson B,Linton SJ,Boersma K,Schrooten M,Repsilber D,Brummer RJ

更新日期：2017-01-01 00:00:00

abstract：Purpose:To investigate the oncological outcome and survival of patients following a conservative approach on the portal-mesenteric axis, in an intraoperative ultrasound-selected group of pancreatoduodenectomy (PD), performed on patients with primary resectable with vascular contact (prVC) pancreatic ductal adenocarcino...

journal_title：Gastroenterology research and practice

authors： Morelli L,Berchiolli R,Guadagni S,Palmeri M,Furbetta N,Gianardi D,Bianchini M,Funel N,Caprili G,Pollina LE,Di Candio G,Mosca F,Di Franco G,Cuschieri A

更新日期：2018-11-25 00:00:00

abstract：:Primary biliary cirrhosis (PBC) is a chronic cholestatic liver condition characterized by the immune-mediated damage of the intrahepatic bile ducts. Polymorphisms of vitamin D receptor (VDR) are considered to contribute to its pathogenesis however their incidence varies in different populations and their potential ass...

journal_title：Gastroenterology research and practice

authors： Kempińska-Podhorecka A,Wunsch E,Jarowicz T,Raszeja-Wyszomirska J,Loniewska B,Kaczmarczyk M,Milkiewicz M,Milkiewicz P

更新日期：2012-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) ranks second amongst all causes of cancer deaths globally. It is on a rise in Pakistan and might represent the most common cancer in adult males. Pakistan contributes significantly to global burden of hepatitis C, which is a known risk factor for HCC, and has one of the highest prevalenc...

journal_title：Gastroenterology research and practice

authors： Hafeez Bhatti AB,Dar FS,Waheed A,Shafique K,Sultan F,Shah NH

更新日期：2016-01-01 00:00:00

abstract：Background/Aims:The damage of interstitial cells of Cajal and smooth muscle cells has far-reaching implications in the pathogenesis of gastroparesis in diabetic patients. Gastric electrical stimulation (GES) is an efficient therapy for gastric motility disorders, but the mechanisms of GES require clarification. Method...

journal_title：Gastroenterology research and practice

authors： Chen Y,Wang H,Li H,Liu S

更新日期：2018-11-13 00:00:00

abstract：Background and Aims:Balloon-assisted enteroscopy (BAE) can be used to retrieve small intestinal foreign bodies (FBs). Here, we aimed at exploring the clinical usefulness of BAE for the retrieval of small intestinal FBs. Methods:We retrospectively reviewed the medical records of 34 patients who underwent BAE to retriev...

journal_title：Gastroenterology research and practice

authors： Kim J,Lee BJ,Ham NS,Oh EH,Choi KD,Ye BD,Byeon JS,Eun CS,Kim JS,Yang DH

更新日期：2020-05-19 00:00:00

abstract：:The objective of this study was to evaluate the possibility to undertake an ileocolic resection in complex Crohn's disease using a minimal open abdominal access using standard laparoscopic instruments. The incision was carried out over the previous McBurney scar, with a mean length of 6 cm. Seventy-two patients with c...

journal_title：Gastroenterology research and practice

authors： Sica GS,Di Carlo S,D'Ugo S,Arcudi C,Siragusa L,Fazzolari L,Biancone L,Monteleone G,Cardi M,Sibio S

更新日期：2020-02-28 00:00:00

abstract：:Background. Surgical treatment of hydatid liver disease (HLD) is divided into conservative and radical procedures. While conservative techniques are easier and faster to perform, there is an emerging need to reduce their morbidity and recurrence rates. Our aim was to present and evaluate the efficiency and safety of t...

journal_title：Gastroenterology research and practice

authors： Mantonakis E,Papalampros A,Moris D,Dimitrokallis N,Sakarellos P,Griniatsos J,Felekouras E

更新日期：2016-01-01 00:00:00