Abstract:
BACKGROUND:Paroxysmal occipital discharges (PODs) demonstrating the phenomena of fixation-off sensitivity have classically been described in childhood epilepsies with occipital paroxysms. AIM:We attempted to delineate the demographic, clinical and imaging characteristics of patients whose interictal electroencephalograms (EEGs) showed occipital discharges with fixation-off sensitivity at our center. MATERIALS AND METHODS:During the period between 2003 and 2005, patients whose interictal EEGs showed PODs were included in the study. A detailed history, clinical examination and EEG findings along with imaging characteristics were analyzed. RESULTS:Of the 9,104 interictal EEGs screened during the study period, 11 patients (6 females and 5 males) aged between 5 and 17 years were identified to have PODs with fixation-off sensitivity. Five had history of generalized tonic-clonic seizures. Three patients could be classified under Panayiotopoulos syndrome; the remaining 8 (72.2%) patients had symptomatic epilepsy. CONCLUSION:This study suggests that the phenomenon of fixation-off sensitivity is found not only in patients of idiopathic focal epilepsies, but also in a substantial number of patients of symptomatic epilepsy. The high proportion of symptomatic epilepsy with phenomenon of fixation-off sensitivity may be related to the referral pattern.
journal_name
Neurol Indiajournal_title
Neurology Indiaauthors
Kaul B,Shukla G,Goyal V,Srivastava A,Behari Mdoi
10.4103/0028-3886.103183subject
Has Abstractpub_date
2012-09-01 00:00:00pages
461-4issue
5eissn
0028-3886issn
1998-4022pii
ni_2012_60_5_461_103183journal_volume
60pub_type
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