Abstract：
:Calcium (Ca) and phosphorus (P) homeostasis were determined in 18 infants (birth weight, 2,810 +/- 135 g; gestational age, 37.4 +/- 0.5 weeks; mean +/- SEM) who received high or low Ca and P content (Ca, P) parenteral nutrition (PN) with a fixed, low dose of vitamin D (25 IU/dl). Nine infants were randomized into low (standard) Ca, P (20 mg Ca and 15.5 mg P/dl) and nine into high Ca, P (60-80 mg Ca and 46.5-62 mg P/dl) PN, and then were studied for up to 6 weeks. The high Ca, P group had stable serum 1,25 dihydroxyvitamin D [1,25(OH)2D], which consistently remained within the normal range (less than 116 pg/ml). Tubular reabsorption of phosphorus (TRP) also was stable and remained consistently less than 90%. The low Ca, P group had elevated and higher 1,25(OH)2D (p = 0.03) than the high Ca, P group. The mean serum 1,25(OH)2D concentration rose from 32 to 112, 115, and 133 pg/ml over a period of 6 weeks. TRP also was higher (p = 0.02) and remained consistently greater than 90%. There were no significant differences between groups in serum parathyroid hormone, calcitonin, Ca, Mg, P, alkaline phosphatase, vitamin D binding protein, and 25 hydroxyvitamin D concentrations; urine Ca/creatinine and Mg/creatinine ratios, and fractional excretion of sodium (Na). Thus, a "high" Ca (60 mg/dl) and P (46.5 mg/dl) content in PN solutions can result in stable serum 1,25(OH)2D and TRP, presumably reflecting minimal stress to Ca and P homeostatic mechanisms without further increase in urinary Ca excretion.
journal_name
J Pediatr Gastroenterol Nutrjournal_title
Journal of pediatric gastroenterology and nutritionauthors
Koo WW,Tsang RC,Steichen JJ,Succop P,Babcock D,Oestreich AE,Noseworthy J,Horn J,Farrell MKsubject
Has Abstractpub_date
1987-01-01 00:00:00pages
96-104issue
1eissn
0277-2116issn
1536-4801journal_volume
6pub_type
临床试验,杂志文章,随机对照试验abstract：BACKGROUND AND OBJECTIVES:Early microbial colonization has a key impact on infant health through nutritional, immunological, and metabolic programming. The origin of child snoring is multifactorial and complex, and may thereby also generate long-term health problems. The link between child snoring and gut microbes rema...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000002161
更新日期：2019-02-01 00:00:00
abstract：OBJECTIVES:Infant colic (IC), with an estimated prevalence of 5% to 25%, has a high impact on health care costs. Furthermore, reported negative sequelae are disturbed parent-infant interaction, increased susceptibility to abdominal pain, and even child abuse. Its etiology remains unknown, leading to a wide variety in i...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章,评审
doi：10.1097/MPG.0000000000000412
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVES:It is unclear how diagnostic tests for gastroesophageal reflux disease (GERD) in children relate to the course of symptoms during follow-up. METHODS:During 1 year, all children (ages 0-18 years), who underwent pH-metry and/or pH multichannel intraluminal impedance (MII), were included after written informed...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000000582
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:There is a strong genetic influence on the susceptibility to celiac disease but it is also evident that environmental factors play a role in the development of the disease. Diverging studies about adenovirus infection as a possible triggering factor in the pathogenesis have been reported. Our study was under...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 评论,杂志文章
doi：10.1097/00005176-200211000-00011
更新日期：2002-11-01 00:00:00
abstract：:In this prospective study, neonates with clinical congenital syphilis were investigated to determine if penicillin therapy caused a deterioration in liver function. The relationship between circulating immune complexes and liver involvement was monitored, and the efficacy of steroid therapy as an adjunct in the treatm...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00005176-199104000-00003
更新日期：1991-04-01 00:00:00
abstract：OBJECTIVES:We aimed to identify early noninvasive predictors of clinical and endoscopic remission in children with Crohn disease (CD) under infliximab (IFX). METHODS:Prospective observational study conducted in children with moderate-to-severe CD starting IFX. All patients underwent weighted pediatric CD activity inde...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000002262
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:The aim of the present study was to examine the effects of early and high intravenous (IV) amino acid (AA) supplementation on growth, health, and neurodevelopment of extremely-low-birth-weight (ELBW) infants throughout their first 2 years of life. METHODS:Infants were prospectively randomized in a double-mas...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1097/MPG.0b013e31824887a0
更新日期：2012-05-01 00:00:00
abstract：OBJECTIVES:Gastrointestinal (GI) mucositis is an adverse-effect of chemo- and radiotherapy. Oral insulin has been suggested as possible intestinal growth factor and possible intervention for GI mucositis. We aimed to determine the effect of oral insulin on the severity and recovery of mucositis in a methotrexate (MTX)-...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000001237
更新日期：2017-02-01 00:00:00
abstract：:To characterize the mechanisms leading to dietary evoked increases of lactase and sucrase activities by carbohydrates, we performed a quantitative comparison of the effects of lactose and sucrose on the corresponding disaccharidases in the jejunum of 2-month-old rats. For 7-10 days the rats were fed a low-starch (5 ca...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-198512000-00024
更新日期：1985-12-01 00:00:00
abstract：BACKGROUND:Liver transplantation is established treatment for children with end-stage liver disease and has a 5-year survival rate of 80% to 85%, even in infants under 12 months. Long-term outcome in nutritional rehabilitation and normal development is unknown. This study aimed to prospectively evaluate growth and psyc...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-200003000-00011
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:Brain-gut axis signaling modifies gastrointestinal symptomatology. Altered neural processing of intestinal pain signals involves interoceptive brain regions in adults with functional and inflammatory gastrointestinal disorders. Although these disorders frequently present in childhood, there are no published ...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000001390
更新日期：2016-11-01 00:00:00
abstract：:Lactoferrin is an iron-binding protein present in high concentrations in human milk. The efficacy of supplementing iron bound to lactoferrin to iron-deficient and iron-sufficient young mice was evaluated in comparison with supplementation of iron as iron chloride. Mice fed a nonsupplemented milk diet (approximately 1 ...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-198311000-00021
更新日期：1983-11-01 00:00:00
abstract：OBJECTIVES:A large retrospective multicentre study was conducted in Spain to evaluate the efficiency of the new European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) criteria for the diagnosis of coeliac disease (CD). METHODS:The study protocol was approved by the ethics committee of Hos...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章,多中心研究
doi：10.1097/MPG.0000000000000870
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVES:Early amino acid administration has been recommended in preterm neonates to avoid protein catabolism. In the present work, blood urea nitrogen (BUN) was used to evaluate the quantity of protein intake in preterm infants. The aim of the study was to investigate the relation between protein intake and BUN duri...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0b013e3181cd270f
更新日期：2010-08-01 00:00:00
abstract：:Prefeeding plasma amino acid concentrations were higher and glycine-to-valine ratios lower in formula-fed infants as compared to breast-fed infants at 3 months of age. After a human milk meal (true protein, 0.8 g/100 ml) or formula meal (1.5 g/100 ml), all essential and several nonessential amino acids peaked at 30-60...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：
更新日期：1983-05-01 00:00:00
abstract：:Twenty-nine children with acute icteric hepatitis were classified as follows after serological tests for the agents of viral hepatitis: hepatitis B 17 patients, hepatitis A 3 patients, hepatitis A + B 1 patient, possible non-A, non-B hepatitis 8 patients. In four of these cases, hepatitis A or non-A, non-B occurred in...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-198807000-00005
更新日期：1988-07-01 00:00:00
abstract：:Breath methane excretion is uncommon in children compared with adults. Certain intracolonic conditions, however, have been associated with enhanced methane generation. We hypothesized that encopretic and constipated children, who have abnormal colonic transit times, more likely would excrete methane than healthy child...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-199005000-00010
更新日期：1990-05-01 00:00:00
abstract：:We studied the effects of breast milk feeding versus formula feeding during the first 8 weeks of life on the development of local gastrointestinal humoral immune response by measuring fecal secretory immunoglobulin A (SIgA). Forty-four infants were studied and classified into two groups: breast milk (n = 21) and stand...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：OBJECTIVE:The aim of the study is to identify additional celiac disease associated loci in the major histocompatibility complex (MHC) independent from classical HLA risk alleles (HLA-DR3-DQ2) and to characterize their potential functional impact in celiac disease pathogenesis at the intestinal level. METHODS:We perfor...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000001970
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:The dietary intake of 63 children with insulin-dependent diabetes mellitus (IDDM; age 10 to 14 years) was weighed by dietitians for 2 days during a summer camp for youth with diabetes. Data were analyzed for the content of macronutrients with the help of a computer database program. METHODS:The dietary inta...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-199908000-00009
更新日期：1999-08-01 00:00:00
abstract：:We compared conventional measures of disease activity with 24-h fecal alpha 1-antitrypsin clearance in 59 children and adolescents with Crohn's disease and 30 with ulcerative colitis. Among the Crohn's patients clearance was increased significantly in those with abnormal erythrocyte sedimentation rates (ESR) (greater ...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-198611000-00015
更新日期：1986-11-01 00:00:00
abstract：BACKGROUND:Ursodeoxycholic acid (UDCA) has been shown to improve pruritus, alanine aminotransferase (ALT), and cholesterol levels in children with intrahepatic cholestatic liver disease. However, the effect of UDCA on quantitative tests of hepatic function in children is uncertain. METHODS:A 2.5-year, open label, cros...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 临床试验,杂志文章
doi：10.1097/00005176-199801000-00009
更新日期：1998-01-01 00:00:00
abstract：:Lymphocytes from 10 paired colostrum and peripheral blood specimens were examined to determine if the colostral T cell population differs from the peripheral blood T cell population in subset distribution. The percentages of lymphocytes staining with OKT3, OKT4, and OKT8 murine monoclonal antibody were determined. Lym...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-198605000-00018
更新日期：1986-05-01 00:00:00
abstract：:The serum levels of five acute phase proteins (APP) were measured in 18 children with Crohn's Disease (CD) or ulcerative colitis (UC) and in two control groups. The levels of C-reactive protein, alpha 1-acid glycoprotein, alpha 1-antitrypsin, C9, and Factor B were significantly raised in patients with CD and UC with g...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-198201020-00007
更新日期：1982-01-01 00:00:00
abstract：:A new statistical approach to the analysis of laboratory data has been introduced to optimize the use of absorption tests and gliadin antibody measurement for the diagnosis of childhood celiac disease. Serum antigliadin antibodies, as well as blood xylose, iron, and tryglycerides after oral load, were evaluated in 40 ...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-198707000-00008
更新日期：1987-07-01 00:00:00
abstract：:Parasitic infection of the gut is highly prevalent in developing countries and contributes to the severe malnutrition associated with persistent diarrhoea in children. Using random faecal alpha 1-antitrypsin measurements as an index of protein-losing enteropathy, we examined children with and without parasitic infecti...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-199211000-00006
更新日期：1992-11-01 00:00:00
abstract：:Severity scores are used to predict the outcome of acute pancreatitis (AP). Several scores are used in adult patients, but none has been thoroughly validated for specific use in paediatric patients. We retrospectively collected data from 48 children with AP (13 severe and 35 mild). The main causes were trauma (23%), i...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0b013e318254c1c7
更新日期：2012-09-01 00:00:00
abstract：:The plasma endotoxin levels of 16 severely malnourished Thai children were determined by the Limulus amebocyte lysate assay. Endotoxemia was present in seven children (44%) on admission to the hospital and was associated with the coexistence of vitamin A deficiency. Protein-energy malnutrition is associated with the p...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-198803000-00012
更新日期：1988-03-01 00:00:00
abstract：OBJECTIVE:By reviewing the literature, lessons learned and experience regarding the nutrition-related health problems of preschool children, draw conclusions and make recommendations on education and nutrition policies for young children. RESULTS:The most common causes of under-5 mortality in low-income countries have...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 社论
doi：10.1097/01.mpg.0000255851.30400.e7
更新日期：2006-12-01 00:00:00
abstract：:Recurrent bouts of abdominal pain in a 12-year-old patient were diagnosed as due to intermittent obstruction of the choledochus. The condition was corrected by choledochostomy. Incidental liver biopsy showed atypia of intrahepatic histiocytes. However, electron microscopy identified associated foreign bodies suspected...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-198605000-00025
更新日期：1986-05-01 00:00:00
