Abstract：
:There have been several recent studies addressing the genetic architecture of depression. This review serves to take stock of what is known now about the genetics of depression, how it has increased our knowledge and understanding of its mechanisms, and how the information and knowledge can be leveraged to improve the care of people affected. We identify four priorities for how the field of MD genetics research may move forward in future years, namely by increasing the sample sizes available for genome-wide association studies (GWASs), greater inclusion of diverse ancestries and low-income countries, the closer integration of psychiatric genetics with electronic medical records, and the development of the neuroscience toolkit for polygenic disorders.
journal_name
Neuronjournal_title
Neuronauthors
McIntosh AM,Sullivan PF,Lewis CMdoi
10.1016/j.neuron.2019.03.022subject
Has Abstractpub_date
2019-04-03 00:00:00pages
91-103issue
1eissn
0896-6273issn
1097-4199pii
S0896-6273(19)30285-5journal_volume
102pub_type
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