Application of a biomarker response index for ranking the toxicity of five pharmaceutical and personal care products (PPCPs) to the bivalve Dreissena polymorpha.

Abstract:

:Pharmaceuticals and personal care products (PPCPs) have been detected in several aquatic ecosystems during the last two decades, but their potential for biological effects to nontarget organisms is only now being studied. The aim of this study was to compare and rank the cyto-genetic effects induced by 96-hour exposure to an environmental concentration (1 nM) of triclosan (TCS), trimethoprim (TMP), diclofenac (DCF), ibuprofen (IBU), and paracetamol (PCM) on the freshwater bivalve Dreissena polymorpha by integrating biological responses of eight biomarker into a simple biomarker response index (BRI). The application of the BRI decreased the wide biomarker variability and enabled toxicity ranking of the tested PPCPs as follow: TCS > TMP > IBU > DCF = PCM. This approach allowed us to draw an accurate PPCP scale of toxicity of the most dangerous drug and to address further in-depth investigations.

authors

Parolini M,Pedriali A,Binelli A

doi

10.1007/s00244-012-9847-3

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

439-47

issue

3

eissn

0090-4341

issn

1432-0703

journal_volume

64

pub_type

杂志文章
  • Toxic effects produced by microcystins from a natural cyanobacterial bloom and a Microcystis aeruginosa isolated strain on the fish cell lines RTG-2 and PLHC-1.

    abstract::Toxic cyanobacterial blooms are a worldwide problem, causing serious water pollution and public health hazard to humans and livestock. The intact cells as well as the toxins released after cellular lysis can be responsible for toxic effects in both animals and humans and are actually associated with fish kills. Two fi...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-005-0122-8

    authors: Pichardo S,Jos A,Zurita J,Salguero M,Camean AM,Repetto G

    更新日期:2006-07-01 00:00:00

  • Concentrations of selected heavy metals in bones and femoral bone structure of bank (Myodes glareolus) and common (Microtus arvalis) voles from different polluted biotopes in Slovakia.

    abstract::Concentrations of selected heavy metals in the femora and femoral bone structure of bank (Myodes glareolus) and common (Microtus arvalis) voles from different polluted biotopes in Slovakia (Kolíňany and Nováky sites) were investigated. Length, weight, and histological structure of vole bones were also analyzed. We obs...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-010-9545-y

    authors: Martiniaková M,Omelka R,Jančová A,Stawarz R,Formicki G

    更新日期:2011-04-01 00:00:00

  • Effects of the insecticide endosulfan and presence of congeneric tadpoles on Australian treefrog (Litoria freycineti) tadpoles.

    abstract::The organochlorine insecticide endosulfan is extensively used in Australia and can often contaminate aquatic environments. However, its effects on Australian frog species are unknown. We exposed tadpoles of the Australian treefrog Litoria frevcineti to endosulfan for 96 hours. Tadpoles exposed to 0.03 or 1.3 microg/L ...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-003-0172-8

    authors: Broomhall S,Shine R

    更新日期:2003-08-01 00:00:00

  • Content of Trace Elements in Soils of Eastern Antarctica: Variability Across Landscapes.

    abstract::Although Antarctica is considered one of the most pristine areas on Earth, an accelerating human presence in this remote continent, such as scientific operations and functioning of numerous scientific stations, logistics, and tourism activities, has increased the risks of environmental impacts in recent decades. Durin...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-021-00808-4

    authors: Alekseev I,Abakumov E

    更新日期:2021-01-21 00:00:00

  • Baseline trace metals in seagrass, algae, and mollusks in a southern Tyrrhenian ecosystem (Linosa Island, Sicily).

    abstract::Trace elements were analyzed in organisms collected at five sampling stations along coastal areas of Linosa Island, Sicily (southern Tyrrhenian Sea, Italy). Concentrations of Cd, Cr, Cu, Pb, and Zn were measured in Posidonia oceanica L. Delile tissues, the two brown algae Padina pavonica (L.) Thivy and Cystoseira sp.,...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-009-9331-x

    authors: Conti ME,Bocca B,Iacobucci M,Finoia MG,Mecozzi M,Pino A,Alimonti A

    更新日期:2010-01-01 00:00:00

  • Determination of textile dyes in organs of Oncorhynchus mykiss W. after in vitro exposure.

    abstract::The quantitative determination in organs of Oncorhynchus mykiss W. of a premetallized dye (C.I. Acid Violet 66) and the azoic base (C.I. Acid Red 217), used in wool dyeing, is studied in this paper. UV-VIS Spectrophotometry was used for the chromatic quantification and atomic absorption spectrophotometry for the detec...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/BF00212276

    authors: Riva MC,Flos R,Crespi M,Pepió M

    更新日期:1992-08-01 00:00:00

  • An Evaluation of Select Test Variables Potentially Affecting Acute Oil Toxicity.

    abstract::In the wake of the Deepwater Horizon incident (2010) in the Gulf of Mexico, an abundance of research studies have been performed, but the methodologies used have varied making comparisons and replication difficult. In this study, acute toxicity tests with mysids and inland silversides were performed to examine the eff...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-015-0228-6

    authors: Echols BS,Smith A,Gardinali P,Rand G

    更新日期:2016-02-01 00:00:00

  • Oxidative stress biomarkers in the digestive gland of Theba pisana exposed to heavy metals.

    abstract::The in vivo toxic effects of sublethal treatment of 40 and 80% of 48-h LD(50) of topically applied trace metals [copper (Cu), lead (Pb), and zinc (Zn)] on oxidative stress biomarkers in the digestive gland of Theba pisana were examined. Oxidative individual perturbations were assessed by measuring nonenzymatic (glutat...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-009-9380-1

    authors: Radwan MA,El-Gendy KS,Gad AF

    更新日期:2010-04-01 00:00:00

  • Legacy and Emerging Brominated Flame Retardants in Bizerte Lagoon Murex (Hexaplex Trunculus): Levels and Human Health Risk Assessment.

    abstract::Occurrence of traditional (PBDEs) and novel (HBB, PBEB, DBDPE) brominated flame retardants, as well as the natural compounds of MeO-PBDEs, were studied in a shellfish species (Hexaplex trunculus) sampled from Bizerte Lagoon. PBDE and MeO-PBDE mean concentrations in murex soft tissues were 187 and 264 ng g-1 lw respect...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-019-00694-x

    authors: Ameur WB,Annabi A,El Megdiche Y,Mhadhbi T,Hassine SB,Barhoumi B,Touil S,Driss MR,Barceló D,Eljarrat E

    更新日期:2020-04-01 00:00:00

  • Challenges to Oil Spill Assessment for Seabirds in the Deep Ocean.

    abstract::We synthesize impediments for evaluating effects to seabirds from open ocean hydrocarbon releases. Effects on seabirds from ship discharges, spills, and well blowouts often are poorly detected and monitored far from land. Regulatory regimes for ocean spills can result in monitoring efforts that are not entirely transp...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-016-0355-8

    authors: Haney JC,Jodice PGR,Montevecchi WA,Evers DC

    更新日期:2017-07-01 00:00:00

  • Distribution of organic microcontaminants, butyltins, and metals in mussels from the Estuary of Bilbao.

    abstract::Mussels are used as bioindicators of chemical pollution in coastal and estuarine waters. We measured the concentrations of polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), phthalate esters (PEs), butyltins, and metals (Cd, Co, Cr, Cu, Hg, Mn, Ni, Pb, V, and Zn) in mussel tissues collected fro...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-009-9458-9

    authors: Bartolomé L,Etxebarria N,Martínez-Arkarazo I,Raposo JC,Usobiaga A,Zuloaga O,Raingeard D,Ortiz-Zarragoitia M,Cajaraville MP

    更新日期:2010-08-01 00:00:00

  • Accumulation of environmental contaminants in wood duck (Aix sponsa) eggs, with emphasis on polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans.

    abstract::We measured polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs), organochlorine pesticides, and mercury in wood duck (Aix sponsa) eggs collected near a North Carolina (USA) bleached kraft paper mill. Samples were taken a decade after the mill stopped using...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-008-9199-1

    authors: Augspurger TP,Echols KR,Peterman PH,May TW,Orazio CE,Tillitt DE,Di Giulio RT

    更新日期:2008-11-01 00:00:00

  • Distribution, Source Apportionment, and Risk Assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in the Surficial Sediments from the Coastal Areas of Bangladesh.

    abstract::The surficial sediments were collected in winter and summer (2015) from the coastal areas of Bangladesh and analyzed for 16 USEPA priority polycyclic aromatic hydrocarbons (PAHs). The total concentration of PAHs (∑PAHs) were 349.8-11,058.8 and 199.9-17,089.1 ng/g dry weight (dw) in winter and summer, respectively. Sed...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-018-0571-5

    authors: Habibullah-Al-Mamun M,Kawser Ahmed M,Hossain A,Masunaga S

    更新日期:2019-02-01 00:00:00

  • Using matrix solid-phase microextraction (matrix-SPME) to estimate bioavailability of DDTs in soil to both earthworm and vegetables.

    abstract::This study was conducted to find an appropriate approach for the assessment of bioavailability of DDTs in soil to both earthworm and vegetables. Four chemical approaches--Soxhlet extraction with n-hexane, n-butanol agitation extraction, water agitation extraction, and matrix solid-phase microextraction (matrix-SPME)--...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-009-9329-4

    authors: Fang H,Chu X,Wang X,Pang G,Yu Y

    更新日期:2010-01-01 00:00:00

  • Assessment of Ecological Risk and Environmental Behavior of Pesticides in Environmental Compartments of the Formoso River in Tocantins, Brazil.

    abstract::Anthropogenic interference the ecosystem unavoidably changes the physical and biological environment. The biodiversity of the Amazon region has been threatened by increased agricultural production and pesticide use. Considering that monitoring pesticides in environments close to their application is one of the ways to...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-020-00770-7

    authors: Guarda PM,Pontes AMS,Domiciano RS,Gualberto LDS,Mendes DB,Guarda EA,da Silva JEC

    更新日期:2020-11-01 00:00:00

  • Considerations for assessments of wadable drainage systems in the agriculturally dominated deltas of Arkansas and Mississippi.

    abstract::The watershed approach, currently used to assess regional streams in the United States, emphasizes least-disturbed reference conditions. Consideration of extensive wadable drainage systems found in Arkansas and Mississippi deltas challenges concepts of disturbance within a landscape of historic agricultural land use. ...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-008-9136-3

    authors: Stephens WW,Moore MT,Farris JL,Bouldin JL,Cooper CM

    更新日期:2008-10-01 00:00:00

  • Exposure to omethoate during stapling of ornamental plants in intensive cultivation tunnels: influence of environmental conditions on absorption of the pesticide.

    abstract::This report describes a study of exposure to omethoate during manual operations with ornamental plants in two intensive cultivation tunnels (tunnel 8 and tunnel 5). Airborne concentrations of omethoate were in the range 1.48-5.36 nmol/m(3). Total skin contamination in the range 329.94-12,934.46 nmol/day averaged 98.1 ...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-005-8025-2

    authors: Aprea C,Centi L,Santini S,Lunghini L,Banchi B,Sciarra G

    更新日期:2005-11-01 00:00:00

  • Mercury in Morelet's crocodile eggs from northern Belize.

    abstract::Recent studies have examined mercury accumulation in crocodilians. However, though most researchers have focused on tissue concentrations, few have examined mercury levels in crocodilian eggs. In July 1995, we analyzed mercury in 31 nonviable Morelet's crocodile ( Crocodylus moreletii) eggs collected from eight nests ...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-001-0020-7

    authors: Rainwater TR,Adair BM,Platt SG,Anderson TA,Cobb GP,McMurry ST

    更新日期:2002-04-01 00:00:00

  • Distribution of hydrophobic ionizable xenobiotics between water and lipid membranes: pentachlorophenol and pentachlorophenate. A comparison with octanol-water partition.

    abstract::We have studied distribution of pentachlorophenol (PCP)--a major environmental pollutant--between egg-phosphatidylcholine (egg-PC) membranes and water. The objectives were (1) to compare the membrane-water partition of the un-ionized (HA) and ionized (A) PCP, and (2) to establish similarities and differences between t...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/BF00210732

    authors: Smejtek P,Wang S

    更新日期:1993-09-01 00:00:00

  • Liver injury and its molecular mechanisms in mice caused by exposure to cerium chloride.

    abstract::Cerium has been demonstrated to damage liver of mice, but very little is known about the molecular mechanisms underlying the mouse liver apoptosis. In order to understand the liver injury induced by intragastric administration of cerium chloride (CeCl3) for 60 consecutive days, the hepatocyte ultrasrtucture, various o...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-011-9672-0

    authors: Zhao H,Cheng J,Cai J,Cheng Z,Cui Y,Gao G,Hu R,Gong X,Wang L,Hong F

    更新日期:2012-01-01 00:00:00

  • Seasonal and geographical variation of organochlorine residues in birds from northwest Mexico.

    abstract::Eight species of birds (129 individuals) were collected from three agricultural areas with long histories of pesticide use in northwestern Mexico. Plucked carcasses were analyzed for organochlorine (OC) pesticides and polychlorobiphenyls (PCBs). DDE was found in all of the samples and at higher levels than other OCs. ...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/BF01183876

    authors: Mora MA,Anderson DW

    更新日期:1991-11-01 00:00:00

  • Evaluating the Effects of Metals on Microorganisms in Flooded Paddy Soils Using the SEM/AVS-Based Approach and Measurements of Exchangeable Metal Concentrations.

    abstract::We examined possible adverse effects of heavy metals on microbial activity, biomass, and community composition using the simultaneously extracted metals (SEM)/acid-volatile sulfide (AVS)-based approach and measurements of exchangeable metal concentrations in three paddy soils (wastewater-contaminated soil, mine-contam...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-017-0387-8

    authors: Kunito T,Toya H,Sumi H,Ishikawa Y,Toda H,Nagaoka K,Saeki K,Aikawa Y,Matsumoto S

    更新日期:2017-04-01 00:00:00

  • Distribution of selected PCB congeners in the Babcock Street sewer district: a multimedia approach to identify PCB sources in combined sewer overflows (CSOs) discharging to the Buffalo River, New York.

    abstract::To evaluate sources of PCBs in combined sewer overflows (CSOs) to the Buffalo River, New York, combined sewage, sanitary flow, atmospheric wet and dry depositions, and street dust samples were collected from the Babcock Street sewer district and analyzed. Total PCB concentrations (sum of the PCB congeners quantitated)...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s002449900234

    authors: Loganathan BG,Irvine KN,Kannan K,Pragatheeswaran V,Sajwan KS

    更新日期:1997-08-01 00:00:00

  • Dehalogenation of xenobiotics as a consequence of binding to humic materials.

    abstract::Chlorinated phenols and anilines were transformed by oxidoreductive catalysts with release of chloride ions in both the absence and the presence of humic substances (syringaldehyde, catechol, and humic acid). Dehalogenation of these xenobiotics resulted from oxidative coupling reactions occurring at the chlorinated si...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s002449910054

    authors: Park JW,Dec J,Kim JE,Bollag JM

    更新日期:2000-05-01 00:00:00

  • Polycyclic aromatic hydrocarbons and ecotoxicological characterization of seawater, sediment, and mussel Mytilus galloprovincialis from the Gulf of Rijeka, the Adriatic Sea, Croatia.

    abstract::The pattern of spatial distribution of polycyclic aromatic hydrocarbons (PAHs) in seawater, sediment, and mussels, potential toxicity of different matrices, and mussel anoxic survival from six sampling sites of the Gulf of Rijeka, the Adriatic Sea, Croatia was examined. The total concentrations of 10 PAHs vary from be...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-005-0259-5

    authors: Bihari N,Fafandel M,Piskur V

    更新日期:2007-04-01 00:00:00

  • Toxicologic and histopathologic response of the terrestrial salamander Plethodon cinereus to soil exposures of 1,3,5-trinitrohexahydro-1,3,5-triazine.

    abstract::Red-backed salamanders (Plethodon cinereus) were exposed to four different concentrations of 1,3,5-trinitrohexahydro-1,3,5-triazine (RDX) in soil under controlled laboratory conditions for 28 days. Wild-caught P. cinereus (N = 20/treatment) were exposed to target concentrations of 5,000, 1000, 100, 10, and 0 mg RDX/kg...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-004-3242-7

    authors: Johnson MS,Paulus HI,Salice CJ,Checkai RT,Simini M

    更新日期:2004-11-01 00:00:00

  • Laundry parameters as factors in lowering methyl parathion residue in cotton/polyester fabrics.

    abstract::Cotton/polyester fabrics were contaminated with a 1.25% solution of methyl parathion (MeP) emulsifiable concentrate formulation, then laboratory laundered. The laundering variables were detergent type, concentration, water volume, and mechanical agitation. Specimens were unfinished (UN) and soil repellent finished (SR...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/BF01160308

    authors: Hild DN,Laughlin JM,Gold RE

    更新日期:1989-11-01 00:00:00

  • Organochlorine pesticide accumulation and genotoxicity in Mexican free-tailed bats from Oklahoma and New Mexico.

    abstract::The summer population of Mexican free-tailed bats (Tadarida brasiliensis) at Carlsbad Caverns, New Mexico, declined from an estimated 8.7 million in 1936 to 200,000 in 1974; thereafter, it increased to approximately 700,000 in 1991. This decline has been attributed primarily to organochlorine (OC) pesticide contaminat...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/BF00215796

    authors: Thies ML,Thies K,McBee K

    更新日期:1996-02-01 00:00:00

  • Predicting the toxicity of permethrin to Daphnia magna in water using SPME fibers.

    abstract::Multiple factors can influence bioavailability, which can make predictions of toxicity in natural systems difficult. The current study examined the potential use of solid-phase microextraction fibers as a matrix-independent approach to predict the toxicity of permethrin to Daphnia magna across various water sources, i...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-011-9721-8

    authors: Harwood AD,Bunch AR,Flickinger DL,You J,Lydy MJ

    更新日期:2012-04-01 00:00:00

  • Delayed and competitively inhibited excretion of urinary hippuric acid in field workers coexposed to toluene, ethyl benzene, and xylene.

    abstract::The purpose of this study was to investigate whether the metabolic suppression of hippuric acid (HA) occurs in field workers coexposed to toluene, xylene and ethyl benzene. Eleven male spray painters were recruited into this study and monitored for 2 weeks using a repeated-measures study design. The sampling was condu...

    journal_title:Archives of environmental contamination and toxicology

    pub_type: 杂志文章

    doi:10.1007/s00244-006-0084-5

    authors: Mao IF,Chang FK,Chen ML

    更新日期:2007-11-01 00:00:00